162 phenotypes from 22 alleles in 36 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Foxn1nu-2J/Foxn1nu-2J B6(SJL)-Foxn1nu-2J/GrsrJ	abnormal hair follicle bulb morphology	J:192383
	abnormal vibrissa morphology	J:192383
	absent vibrissae	J:192383
	athymia	J:192383
	brittle hair	J:192383
	curly vibrissae	J:192383
	decreased body size	J:192383
	decreased litter size	J:192383
	hairless	J:192383
	increased or absent threshold for auditory brainstem response	J:192383
	premature death	J:192383
	reduced female fertility	J:192383
	short vibrissae	J:192383
	sparse vibrissae	J:192383
	underdeveloped hair follicles	J:192383
	wrinkled skin	J:192383
Foxn1nu-Bc/Foxn1nu-Bc involves: SELH/Bc	abnormal hair growth	J:65317
	hairless	J:65317
Foxn1nu-StL/Foxn1nu-StL involves: C57BL/6	absent T cells	J:63313
	athymia	J:63313
	hairless	J:63313
Foxn1nu-StL/Foxn1tm1Tbo involves: 129S1/Sv * C57BL/6	abnormal thymus development	J:63313
	athymia	J:63313
Foxn1nu-str/Foxn1nu-str AKR/J-Foxn1nu-str/J	abnormal humoral immune response	J:30715
	abnormal immune system cell morphology	J:30715
	abnormal immune system morphology	J:24755
	abnormal immune system organ morphology	J:30715
	abnormal immune system physiology	J:30715
	abnormal Peyer's patch germinal center morphology	J:30715
	abnormal Peyer's patch morphology	J:30715
	athymia	J:24755
	cachexia	J:30715
	decreased immunoglobulin level	J:30715
	decreased incidence of tumors by chemical induction	J:43880
	decreased lymphocyte cell number	J:30715
	decreased lymphoma incidence	J:30715
	decreased T cell number	J:30715
	hairless	J:24755
	increased eosinophil cell number	J:30715
	increased granulocyte number	J:30715
	increased length of allograft survival	J:30715
	increased neutrophil cell number	J:30715
	increased sarcoma incidence	J:30715
	lymph node hypoplasia	J:30715
	premature death	J:30715
	spleen hypoplasia	J:30715
Foxn1nu-Y/Foxn1nu-Y 101/HY-Foxn1nu-Y	abnormal thymus development	J:4060
	absent T cells	J:4060
	athymia	J:4060, J:29022
	decreased body weight	J:4060
	hairless	J:4060
	postnatal lethality, incomplete penetrance	J:4060
Foxn1nu/Foxn1+ B6N.Cg-Foxn1nu	small thymus	J:7330
Foxn1nu/Foxn1+ C3N.Cg-Foxn1nu	small thymus	J:7330
Foxn1nu/Foxn1+ C.Cg-Foxn1nu	small thymus	J:7330
Foxn1nu/Foxn1+ involves: BALB/c	blepharitis	J:12543
	corneal vascularization	J:12543
	increased incidence of corneal inflammation	J:12543
	increased susceptibility to Herpesvirales infection	J:12543
Foxn1nu/Foxn1+ NFS.Cg-Foxn1nu	abnormal thymus morphology	J:7330
	small thymus	J:7330
Foxn1nu/Foxn1nu B6.Cg-Foxn1nu	abnormal compact bone morphology	J:145330
	abnormal trabecular bone morphology	J:145330
	increased bone mineral density	J:145330
Foxn1nu/Foxn1nu B6NTac.Cg-Foxn1nu/Tac	decreased susceptibility to parasitic infection	J:64283
Foxn1nu/Foxn1nu involves: BALB/c	abnormal circulating cytokine level	J:50903
	abnormal nail morphology	J:173664
	ascites	J:40405
	blepharitis	J:12543
	chromosomal instability	J:40405
	decreased circulating alanine transaminase level	J:50903
	decreased circulating interleukin-2 level	J:50903
	decreased circulating interleukin-6 level	J:50903
	decreased circulating tumor necrosis factor level	J:50903
	decreased interferon-gamma secretion	J:50903
	decreased susceptibility to bacterial infection	J:50903
	deformed nails	J:173664
	increased plasmacytoma incidence	J:40405
	increased susceptibility to Herpesvirales infection	J:12543
	increased susceptibility to Herpesvirales infection induced morbidity/mortality	J:12543
	short nails	J:173664
Foxn1nu/Foxn1nu involves: C57BL/10	abnormal muscle morphology	J:95776
	decreased skeletal muscle fiber size	J:95776
	decreased skeletal muscle mass	J:95776
Foxn1nu/Foxn1nu involves: C57BL/10Sn * C57BR/cd	abnormal thymus development	J:7898
Foxn1nu/Foxn1nu involves: CBA	abnormal lymph node morphology	J:202808
	abnormal spleen physiology	J:202299
	abnormal T cell activation	J:202299
	decreased leukocyte cell number	J:202299
	decreased lymphocyte cell number	J:202299
	decreased T cell number	J:202808
	increased length of allograft survival	J:202299
Foxn1nu/Foxn1nu involves: CD-1	abnormal circulating gonadotropin level	J:106251
	athymia	J:106251
	decreased circulating follicle stimulating hormone level	J:106251
	decreased circulating luteinizing hormone level	J:106251
	normal endocrine/exocrine gland phenotype	J:106251
Foxn1nu/Foxn1nu involves: NIH Swiss	premature death	J:5583
Foxn1nu/Foxn1nu involves: NMRI	abnormal coat/ hair morphology	J:94187
	abnormal corneocyte morphology	J:466
	abnormal cutaneous collagen fibril morphology	J:466
	abnormal embryonic tissue morphology	J:6363
	abnormal epidermal layer morphology	J:466
	abnormal epidermis stratum basale morphology	J:466
	abnormal epidermis stratum corneum morphology	J:466
	abnormal epidermis stratum granulosum morphology	J:466
	abnormal hair cortex keratinization	J:466
	abnormal hair cortex morphology	J:466
	abnormal hair cuticle	J:466
	abnormal hair follicle inner root sheath morphology	J:466
	abnormal hair follicle morphology	J:466
	abnormal hair shaft morphology	J:466
	abnormal nail matrix morphology	J:94187
	abnormal nail morphology	J:94187
	abnormal nail plate morphology	J:94187
	abnormal thymus development	J:6363
	deformed nails	J:94187
	normal endocrine/exocrine gland phenotype	J:6363
	nail dystrophy	J:94187
	reduced hair shaft melanin granule number	J:466
	short nails	J:94187
Foxn1nu/Foxn1nu Not Specified	abnormal estrous cycle	J:5043
	abnormal liver morphology	J:5043
	abnormal lymph node T cell domain morphology	J:202296
	abnormal Peyer's patch germinal center morphology	J:202296
	abnormal spleen morphology	J:202296
	abnormal splenic cell ratio	J:202296
	abnormal thymus morphology	J:202297
	abnormal venule morphology	J:202296
	absent vibrissae	J:5043
	asthenozoospermia	J:5043
	athymia	J:5059, J:202296
	coiled sperm flagellum	J:5043
	decreased body size	J:5043
	decreased body weight	J:5043
	decreased leukocyte cell number	J:5059
	female infertility	J:5043
	hairless	J:5043, J:30772
	impaired spatial learning	J:90695
	postnatal growth retardation	J:5043
	postnatal lethality, incomplete penetrance	J:5043
	premature death	J:5043, J:30772
	reduced male fertility	J:5043
	short vibrissae	J:5043
	small ovary	J:5043
	small spleen	J:202296
	thin skin	J:5043
	wavy vibrissae	J:5043
Foxn1nu/Foxn1nu NU/J	abnormal nail matrix morphology	J:94187
	abnormal nail morphology	J:94187
	abnormal nail plate morphology	J:94187
	nail dystrophy	J:94187
Foxn1nu/Foxn1nu Tg(Foxn1)E1Hon/0 involves: CD-1	athymia	J:33866
	hairless	J:33866
Foxn1nu/Foxn1nu Tg(Foxn1)G2Hon/0 involves: CD-1	hairless	J:33866
	infertility	J:33866
Foxn1nu/Foxn1tm1.1Dmsu Tg(CAG-cre/Esr1*)5Amc/0 involves: 129/Sv * C57BL/6 * CBA * SJL	abnormal thymus epithelium morphology	J:159773
	decreased thymocyte number	J:159773
	increased thymocyte apoptosis	J:159773
Foxn1sepe/Foxn1sepe BALB/c-Foxn1sepe	athymia	J:227974
	hairless	J:227974
Foxn1tm1.1(KOMP)Vlcg/Foxn1+ C57BL/6N-Foxn1tm1.1(KOMP)Vlcg/Tcp	hydrometra	J:211773
	small superior vagus ganglion	J:211773
Foxn1tm1.1(KOMP)Vlcg/Foxn1tm1.1(KOMP)Vlcg C57BL/6N-Foxn1tm1.1(KOMP)Vlcg/Tcp	abnormal skin morphology	J:211773
	abnormal thymus morphology	J:211773
	athymia	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Foxn1tm1.1Cbln/Foxn1+ involves: 129P2/OlaHsd * C57BL/6	thymus hyperplasia	J:177992
Foxn1tm1.1Cbln/Foxn1+ Tg(Zp3-cre)3Mrt/? involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * FVB/N	normal immune system phenotype	J:177992
Foxn1tm1.1Cbln/Foxn1tm1.1Cbln involves: 129P2/OlaHsd * C57BL/6	abnormal lymphocyte cell number	J:177992
	decreased single-positive T cell number	J:177992
	increased DN1 thymic pro-T cell number	J:177992
	increased double-positive T cell number	J:177992
	thymus hypoplasia	J:177992
Foxn1tm1.1Cbln/Foxn1tm1Tbo involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	abnormal hair growth	J:177992
	absent T cells	J:177992
	small thymus	J:177992
Foxn1tm1.1Cbln/Foxn1tm1Tbo Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+ involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	normal immune system phenotype	J:177992
Foxn1tm1.1Dmsu/Foxn1tm1.1Dmsu involves: 129/Sv * C57BL/6 * SJL	no abnormal phenotype detected	J:159773
Foxn1tm1.1Dmsu/Foxn1tm1.1Dmsu Tg(CAG-cre/Esr1*)5Amc/0 involves: 129/Sv * C57BL/6 * CBA * SJL	abnormal thymus morphology	J:159773
	decreased double-positive T cell number	J:159773
	decreased thymocyte number	J:159773
	small thymus	J:159773
	thymus atrophy	J:159773
Foxn1tm1.1Dmsu/Foxn1tm1.1Dmsu Tg(KRT5-cre/ERT2)2Ipc/0 involves: 129/Sv * C57BL/6 * SJL	abnormal thymus corticomedullary boundary morphology	J:159773
	abnormal thymus medulla morphology	J:159773
	decreased thymocyte number	J:159773
	small thymus	J:159773
	thymus atrophy	J:159773
Foxn1tm1.1Dmsu/Foxn1tm1.1Dmsu Tg(KRT18-cre/ERT2)1Rgo/0 involves: 129/Sv * C57BL/6 * FVB/N * SJL	normal immune system phenotype	J:159773
Foxn1tm1Dmsu/Foxn1tm1Dmsu involves: 129/Sv * C57BL/6	athymia	J:159773
	hairless	J:159773
Foxn1tm1Nrm/Foxn1+ involves: 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:86255
Foxn1tm1Nrm/Foxn1tm1Nrm involves: 129X1/SvJ * C57BL/6J	abnormal CD4-positive, alpha beta T cell morphology	J:86255
	abnormal CD8-positive, alpha beta T cell morphology	J:86255
	abnormal T cell differentiation	J:86255
	abnormal thymus development	J:86255
	abnormal thymus epithelium morphology	J:86255
	absent thymus cortex	J:86255
	absent thymus medulla	J:86255
	decreased CD4-positive, alpha-beta T cell number	J:86255
	decreased double-negative T cell number	J:86255
	decreased double-positive T cell number	J:86255
	decreased T cell number	J:86255
	decreased thymocyte number	J:86255
	normal integument phenotype	J:86255
	small thymus	J:86255
	thymus cyst	J:86255
Foxn1tm1Tbo/Foxn1tm1Tbo involves: 129S1/Sv	abnormal hair follicle development	J:61394
	abnormal leukocyte cell number	J:33796
	abnormal thymus development	J:33796
	abnormal thymus epithelium morphology	J:177992
	abnormal thymus morphology	J:33796
	absent T cells	J:33796
	athymia	J:33796
	hairless	J:33796
	increased B cell number	J:33796
Foxn1tm2Nrm/Foxn1tm2Nrm either: (involves: 129/Sv) or (involves: C57BL/6)	normal immune system phenotype	J:125817
Foxn1tm2Tbo/Foxn1tm2Tbo involves: 129S1/Sv * 129X1/SvJ * C57BL/6	hairless	J:110046
Foxn1tm2Tbo/Foxn1tm2Tbo Tg(KRT14-cre/ERT2)1Ipc/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	increased T cell number	J:110046
Foxn1tm3(cre)Nrm/Foxn1tm3(cre)Nrm either: (involves: 129/Sv) or (involves: C57BL/6)	normal immune system phenotype	J:125817
Foxn1tw/Foxn1tw involves: 129 * C57BL/6	abnormal skin pigmentation	J:85194
	hairless	J:85194
	underdeveloped hair follicles	J:85194
Gt(ROSA)26Sortm1(CAG-Foxn1/ERT2,-GFP)Cbln/Gt(ROSA)26Sor+ Foxn1tm3(cre)Nrm/Foxn1+ involves: 129P2/OlaHsd * C57BL/6	abnormal thymus involution	J:208852
	normal endocrine/exocrine gland phenotype	J:208852
	increased T cell number	J:208852
Tg(Foxn1)1Jlb/0 involves: C57BL/6 * DBA	absent eyelids	J:56641
	decreased body size	J:56641
	flaky skin	J:56641
	impaired skin barrier function	J:56641
	neonatal lethality, complete penetrance	J:56641
	shiny skin	J:56641
	tight skin	J:56641
Tg(Foxn1)6Jlb/0 involves: C57BL/6 * DBA	alopecia	J:56641
	curly vibrissae	J:56641
	decreased birth body size	J:56641
	delayed hair appearance	J:56641
	hydronephrosis	J:56641
	kinked vibrissae	J:56641
	loss of vibrissae	J:56641
	premature death	J:56641
	scaly muzzle	J:56641
	short hair	J:56641
	sparse hair	J:56641
	underdeveloped hair follicles	J:56641
	ureter urothelium hyperplasia	J:56641
	waved hair	J:56641