Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PSAP
  • Mouse genes Psap
  • Rat genes Psap
  • Zfish genes psap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Psap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	Psap	IPI	UniProtKB:O15354|UniProtKB:O60883	Mouse	MGI:MGI:5586790|PMID:23690594
Molecular Function	GO:1905573	ganglioside GM1 binding	PSAP	IDA		Human	PMID:1454804
Molecular Function	GO:1905574	ganglioside GM2 binding	PSAP	IDA		Human	PMID:1454804
Molecular Function	GO:1905575	ganglioside GM3 binding	PSAP	IDA		Human	PMID:1454804
Molecular Function	GO:1905577	ganglioside GP1c binding	PSAP	IDA		Human	PMID:1454804
Molecular Function	GO:1905576	ganglioside GT1b binding	PSAP	IDA		Human	PMID:1454804
Molecular Function	GO:0042802	identical protein binding	Psap	IPI	PR:Q61207	Mouse	PMID:12867159
Molecular Function	GO:0030882	lipid antigen binding	Psap	IDA		Mouse	PMID:14684827
Molecular Function	GO:0005543	phospholipid binding	PSAP	IDA		Human	PMID:14674747
Molecular Function	GO:0002020	protease binding	PSAP	IPI	UniProtKB:P31944	Human	PMID:24872419
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:O96006	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:P08F94	Human	PMID:20709014
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:Q99523	Human	PMID:22431521
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:P31944	Human	PMID:24872419
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:P24668	Human	PMID:26370502
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:P28799	Human	PMID:26370502
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:O96006	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:P50542-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:Q92624	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:P07948	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PSAP	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Psap	IPI	UniProtKB:P28798	Mouse	MGI:MGI:5701557|PMID:26370502
Molecular Function	GO:0005515	protein binding	Psap	IPI	UniProtKB:P28799,UniProtKB:Q99523	Mouse	MGI:MGI:5920379|PMID:28541286
Molecular Function	GO:0005515	protein binding	Psap	IPI	MGI:MGI:3609260	Mouse	PMID:17167097
Molecular Function	GO:0005515	protein binding	Psap	IPI	PR:P11609	Mouse	PMID:14684827
Molecular Function	GO:0042803	protein homodimerization activity	PSAP	IDA		Human	PMID:18462685
Molecular Function	GO:0097110	scaffold protein binding	PSAP	IPI	UniProtKB:Q8NDB2	Human	PMID:23555801
Cellular Component	GO:0016235	aggresome	Psap	IDA		Mouse	PMID:20498017
Cellular Component	GO:0062023	collagen-containing extracellular matrix	PSAP	HDA		Human	PMID:27559042
Cellular Component	GO:0005737	cytoplasm	Psap	IDA		Mouse	PMID:19732768
Cellular Component	GO:0005737	cytoplasm	Psap	IDA		Mouse	PMID:22326583
Cellular Component	GO:0070062	extracellular exosome	PSAP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PSAP	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	PSAP	HDA		Human	PMID:27068509
Cellular Component	GO:0005576	extracellular region	Psap	IDA		Mouse	MGI:MGI:5920379|PMID:28541286
Cellular Component	GO:0005576	extracellular region	Psap	IDA		Mouse	PMID:19732768
Cellular Component	GO:0005615	extracellular space	PSAP	IDA		Human	PMID:1454804
Cellular Component	GO:0005615	extracellular space	PSAP	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	PSAP	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	Psap	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PSAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005770	late endosome	PSAP	IDA		Human	PMID:26370502
Cellular Component	GO:0005764	lysosome	PSAP	IDA		Human	PMID:22431521
Cellular Component	GO:0005764	lysosome	PSAP	IDA		Human	PMID:26370502
Cellular Component	GO:0005764	lysosome	PSAP	IDA		Human	PMID:28541286
Cellular Component	GO:0005764	lysosome	Psap	IDA		Mouse	PMID:19732768
Cellular Component	GO:0005764	lysosome	Psap	IDA		Mouse	PMID:12867159
Cellular Component	GO:0005764	lysosome	Psap	IDA		Mouse	PMID:29514215
Cellular Component	GO:0005739	mitochondrion	Psap	HDA		Mouse	PMID:14651853
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Psap	IDA		Mouse	MGI:MGI:5586790|PMID:23690594
Biological Process	GO:0019882	antigen processing and presentation	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:14684827
Biological Process	GO:0071310	cellular response to organic substance	Psap	IMP	MGI:MGI:3802531	Mouse	PMID:18480170
Biological Process	GO:0071310	cellular response to organic substance	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:18480170
Biological Process	GO:0006672	ceramide metabolic process	Psap	IMP		Mouse	PMID:17353235
Biological Process	GO:0006672	ceramide metabolic process	Psap	IMP	MGI:MGI:3521746	Mouse	PMID:15345707
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Psap	IMP	MGI:MGI:3521746	Mouse	PMID:15345707
Biological Process	GO:0090102	cochlea development	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:17167097
Biological Process	GO:0003335	corneocyte development	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:24872419
Biological Process	GO:0003335	corneocyte development	Psap	IMP	MGI:MGI:2183897	Mouse	PMID:24872419
Biological Process	GO:1903575	cornified envelope assembly	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:24872419
Biological Process	GO:0048589	developmental growth	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:11105903
Biological Process	GO:0060742	epithelial cell differentiation involved in prostate gland development	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:11105903
Biological Process	GO:0006683	galactosylceramide catabolic process	Psap	IMP	MGI:MGI:2183897	Mouse	PMID:11371512
Biological Process	GO:1905572	ganglioside GM1 transport to membrane	PSAP	IDA		Human	PMID:1454804
Biological Process	GO:0010467	gene expression	Psap	IMP		Mouse	PMID:27356620
Biological Process	GO:0010467	gene expression	Psap	IDA		Mouse	PMID:27356620
Biological Process	GO:0006678	glucosylceramide metabolic process	Psap	IMP		Mouse	PMID:17353235
Biological Process	GO:0006664	glycolipid metabolic process	Psap	IMP		Mouse	PMID:12810822
Biological Process	GO:0070841	inclusion body assembly	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:9678511
Biological Process	GO:0006886	intracellular protein transport	Psap	IMP		Mouse	PMID:17353235
Biological Process	GO:1905146	lysosomal protein catabolic process	Psap	IMP		Mouse	PMID:12813057
Biological Process	GO:0007041	lysosomal transport	PSAP	IDA		Human	PMID:26370502
Biological Process	GO:0007041	lysosomal transport	PSAP	IMP		Human	PMID:28541286
Biological Process	GO:0007041	lysosomal transport	PSAP	IMP		Human	PMID:28835281
Biological Process	GO:0006643	membrane lipid metabolic process	Psap	IDA		Mouse	PMID:14684827
Biological Process	GO:0060073	micturition	Psap	IMP	MGI:MGI:2183897	Mouse	PMID:11371512
Biological Process	GO:0042552	myelination	Psap	IMP	MGI:MGI:2183897	Mouse	PMID:11371512
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	Psap	IDA		Mouse	MGI:MGI:5586790|PMID:23690594
Biological Process	GO:0050877	nervous system process	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:9678511
Biological Process	GO:0050877	nervous system process	Psap	IMP		Mouse	PMID:17353235
Biological Process	GO:0050885	neuromuscular process controlling balance	Psap	IMP	MGI:MGI:3711720	Mouse	PMID:22326583
Biological Process	GO:0001865	NK T cell differentiation	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:14684827
Biological Process	GO:1903771	positive regulation of beta-galactosidase activity	PSAP	IDA		Human	PMID:1454804
Biological Process	GO:0051345	positive regulation of hydrolase activity	Psap	IMP	MGI:MGI:2183897	Mouse	PMID:11371512
Biological Process	GO:0043410	positive regulation of MAPK cascade	Psap	IDA		Mouse	MGI:MGI:5586790|PMID:23690594
Biological Process	GO:0060736	prostate gland growth	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:11105903
Biological Process	GO:0009306	protein secretion	Psap	IMP		Mouse	PMID:17353235
Biological Process	GO:0019216	regulation of lipid metabolic process	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:18480170
Biological Process	GO:0019216	regulation of lipid metabolic process	Psap	IMP	MGI:MGI:3802531	Mouse	PMID:18480170
Biological Process	GO:0043408	regulation of MAPK cascade	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:11105903
Biological Process	GO:0072001	renal system development	Psap	IMP	MGI:MGI:3521746	Mouse	PMID:15345707
Biological Process	GO:0007605	sensory perception of sound	Psap	IMP	MGI:MGI:1888378	Mouse	PMID:17167097
Biological Process	GO:0007605	sensory perception of sound	Psap	IMP	MGI:MGI:3711720	Mouse	PMID:22326583
Biological Process	GO:0006665	sphingolipid metabolic process	Psap	IMP	MGI:MGI:2183897	Mouse	PMID:11371512
Biological Process	GO:0090659	walking behavior	Psap	IMP	MGI:MGI:3711720	Mouse	PMID:22326583

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern