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Gene Ontology Browser
Term Detail
GO term:myelination
GO id:GO:0042552
Definition:The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
Number of paths to term: 16

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-aaction potential
                                                is-aneuronal action potential
                                                        regulatesensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-oftransmission of nerve impulse
                                                part-ofneuronal action potential
                                                        regulatesensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-aensheathment of neurons
                                        is-aaxon ensheathment
                                                is-aaxon ensheathment in central nervous system +
                                                is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                        is-acentral nervous system myelination +
                                                        part-ofmyelin assembly +
                                                        part-ofmyelin maintenance +
                                                        is-amyelination in peripheral nervous system +
                                                        is-amyelination of lateral line nerve axons +
                                                        negatively-regulatesnegative regulation of myelination
                                                        positively-regulatespositive regulation of myelination
                                                        regulatesregulation of myelination +
                                                is-anon-myelinated axon ensheathment +
                                                is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-anervous system development
                                                part-ofensheathment of neurons
                                                        is-aaxon ensheathment
                                                                is-aaxon ensheathment in central nervous system +
                                                                is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                        is-acentral nervous system myelination +
                                                                        part-ofmyelin assembly +
                                                                        part-ofmyelin maintenance +
                                                                        is-amyelination in peripheral nervous system +
                                                                        is-amyelination of lateral line nerve axons +
                                                                        negatively-regulatesnegative regulation of myelination
                                                                        positively-regulatespositive regulation of myelination
                                                                        regulatesregulation of myelination +
                                                                is-anon-myelinated axon ensheathment +
                                                                is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal signaling
                                        is-atransmission of nerve impulse
                                                part-ofneuronal action potential
                                                        regulatesensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-aneurological system process
                                                is-atransmission of nerve impulse
                                                        part-ofneuronal action potential
                                                                regulatesensheathment of neurons
                                                                        is-aaxon ensheathment
                                                                                is-aaxon ensheathment in central nervous system +
                                                                                is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                        is-acentral nervous system myelination +
                                                                                        part-ofmyelin assembly +
                                                                                        part-ofmyelin maintenance +
                                                                                        is-amyelination in peripheral nervous system +
                                                                                        is-amyelination of lateral line nerve axons +
                                                                                        negatively-regulatesnegative regulation of myelination
                                                                                        positively-regulatespositive regulation of myelination
                                                                                        regulatesregulation of myelination +
                                                                                is-anon-myelinated axon ensheathment +
                                                                                is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                is-amulticellular organismal signaling
                                        is-atransmission of nerve impulse
                                                part-ofneuronal action potential
                                                        regulatesensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                is-amulticellular organismal signaling
                                        is-atransmission of nerve impulse
                                                part-ofneuronal action potential
                                                        regulatesensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal signaling
                                        is-atransmission of nerve impulse
                                                part-ofneuronal action potential
                                                        regulatesensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-aneurological system process
                                                is-atransmission of nerve impulse
                                                        part-ofneuronal action potential
                                                                regulatesensheathment of neurons
                                                                        is-aaxon ensheathment
                                                                                is-aaxon ensheathment in central nervous system +
                                                                                is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                        is-acentral nervous system myelination +
                                                                                        part-ofmyelin assembly +
                                                                                        part-ofmyelin maintenance +
                                                                                        is-amyelination in peripheral nervous system +
                                                                                        is-amyelination of lateral line nerve axons +
                                                                                        negatively-regulatesnegative regulation of myelination
                                                                                        positively-regulatespositive regulation of myelination
                                                                                        regulatesregulation of myelination +
                                                                                is-anon-myelinated axon ensheathment +
                                                                                is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-oftransmission of nerve impulse
                                                part-ofneuronal action potential
                                                        regulatesensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-aensheathment of neurons
                                        is-aaxon ensheathment
                                                is-aaxon ensheathment in central nervous system +
                                                is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                        is-acentral nervous system myelination +
                                                        part-ofmyelin assembly +
                                                        part-ofmyelin maintenance +
                                                        is-amyelination in peripheral nervous system +
                                                        is-amyelination of lateral line nerve axons +
                                                        negatively-regulatesnegative regulation of myelination
                                                        positively-regulatespositive regulation of myelination
                                                        regulatesregulation of myelination +
                                                is-anon-myelinated axon ensheathment +
                                                is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (117 genes, 152 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory