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Gene Ontology Browser
Term Detail
GO term:myelination
Synonym: myelinogenesis
GO id:GO:0042552
Definition:The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-aensheathment of neurons
                                        is-aaxon ensheathment
                                                is-aaxon ensheathment in central nervous system +
                                                is-amyelination [GO:0042552] (122 genes, 157 annotations)
                                                        is-acentral nervous system myelination +
                                                        part-ofmyelin assembly +
                                                        part-ofmyelin maintenance +
                                                        is-amyelination in peripheral nervous system +
                                                        is-amyelination of lateral line nerve axons +
                                                        negatively-regulatesnegative regulation of myelination
                                                        positively-regulatespositive regulation of myelination
                                                        regulatesregulation of myelination +
                                                is-anon-myelinated axon ensheathment +
                                                is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-anervous system development
                                                part-ofensheathment of neurons
                                                        is-aaxon ensheathment
                                                                is-aaxon ensheathment in central nervous system +
                                                                is-amyelination [GO:0042552] (122 genes, 157 annotations)
                                                                        is-acentral nervous system myelination +
                                                                        part-ofmyelin assembly +
                                                                        part-ofmyelin maintenance +
                                                                        is-amyelination in peripheral nervous system +
                                                                        is-amyelination of lateral line nerve axons +
                                                                        negatively-regulatesnegative regulation of myelination
                                                                        positively-regulatespositive regulation of myelination
                                                                        regulatesregulation of myelination +
                                                                is-anon-myelinated axon ensheathment +
                                                                is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (122 genes, 157 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (122 genes, 157 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (122 genes, 157 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-aensheathment of neurons
                                        is-aaxon ensheathment
                                                is-aaxon ensheathment in central nervous system +
                                                is-amyelination [GO:0042552] (122 genes, 157 annotations)
                                                        is-acentral nervous system myelination +
                                                        part-ofmyelin assembly +
                                                        part-ofmyelin maintenance +
                                                        is-amyelination in peripheral nervous system +
                                                        is-amyelination of lateral line nerve axons +
                                                        negatively-regulatesnegative regulation of myelination
                                                        positively-regulatespositive regulation of myelination
                                                        regulatesregulation of myelination +
                                                is-anon-myelinated axon ensheathment +
                                                is-aperipheral nervous system axon ensheathment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofensheathment of neurons
                                                                is-aaxon ensheathment
                                                                        is-aaxon ensheathment in central nervous system +
                                                                        is-amyelination [GO:0042552] (122 genes, 157 annotations)
                                                                                is-acentral nervous system myelination +
                                                                                part-ofmyelin assembly +
                                                                                part-ofmyelin maintenance +
                                                                                is-amyelination in peripheral nervous system +
                                                                                is-amyelination of lateral line nerve axons +
                                                                                negatively-regulatesnegative regulation of myelination
                                                                                positively-regulatespositive regulation of myelination
                                                                                regulatesregulation of myelination +
                                                                        is-anon-myelinated axon ensheathment +
                                                                        is-aperipheral nervous system axon ensheathment +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/28/2015
MGI 5.21
The Jackson Laboratory