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Gene Ontology Browser
Term Detail
GO term:antigen processing and presentation
Synonym: antigen presentation
Synonym: antigen processing
GO id:GO:0019882
Definition:The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
CommentsThis term was improved by GO_REF:0000022. It was renamed and redefined.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aactivation of immune response +
                        is-aantigen processing and presentation [GO:0019882] (109 genes, 179 annotations)
                                is-aantigen processing and presentation following phagocytosis +
                                is-aantigen processing and presentation following pinocytosis +
                                is-aantigen processing and presentation initiated by receptor mediated uptake of antigen +
                                is-aantigen processing and presentation of endogenous antigen +
                                is-aantigen processing and presentation of exogenous antigen +
                                is-aantigen processing and presentation of peptide antigen +
                                is-aantigen processing and presentation of peptide or polysaccharide antigen via MHC class II +
                                is-aantigen processing and presentation via MHC class Ib +
                                is-aB cell antigen processing and presentation +
                                is-adendritic cell antigen processing and presentation +
                                is-amacrophage antigen processing and presentation +
                                is-amonocyte antigen processing and presentation +
                                negatively-regulatesnegative regulation of antigen processing and presentation +
                                is-anon-professional antigen presenting cell antigen processing and presentation +
                                positively-regulatespositive regulation of antigen processing and presentation +
                                regulatesregulation of antigen processing and presentation +
                                is-aT cell antigen processing and presentation +
                        is-aantigen sampling in mucosal-associated lymphoid tissue +
                        is-aB cell selection +
                        is-ahemocyte differentiation +
                        is-ahemocyte proliferation +
                        is-aimmune effector process +
                        is-aimmune response +
                        is-aimmune system development +
                        is-aleukocyte activation +
                        is-aleukocyte homeostasis +
                        is-aleukocyte migration +
                        is-alymphocyte costimulation +
                        is-amyeloid cell homeostasis +
                        negatively-regulatesnegative regulation of immune system process +
                        positively-regulatespositive regulation of immune system process +
                        is-aproduction of molecular mediator of immune response +
                        regulatesregulation of immune system process +
                        is-asomatic diversification of immune receptors +
                        is-aT cell selection +
                        is-atolerance induction +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory