Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nfkbiz

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NFKBIZ
- Mouse genes Nfkbiz
- Rat genes Nfkbiz
- Zfish genes nfkbiz
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfkbiz

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NFKBIZ	IPI	UniProtKB:B1AXD8	Human	PMID:25107474
Molecular Function	GO:0005515	protein binding	Nfkbiz	IPI	UniProtKB:B1AXD8	Mouse	MGI:MGI:5607662\|PMID:25107474
Molecular Function	GO:0005515	protein binding	Nfkbiz	IPI	UniProtKB:Q64669	Mouse	PMID:29934320
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nfkbiz	IDA		Mouse	PMID:20383124
Molecular Function	GO:0003712	transcription coregulator activity	Nfkbiz	IDA		Mouse	PMID:15618216
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	NFKBIZ	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	NFKBIZ	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Nfkbiz	IDA		Mouse	PMID:15618216
Cellular Component	GO:0005634	nucleus	Nfkbiz	IDA		Mouse	PMID:29934320
Cellular Component	GO:0005634	nucleus	Nfkbiz	IDA		Mouse	PMID:11086164
Biological Process	GO:0002250	adaptive immune response	Nfkbiz	IDA		Mouse	PMID:17367755
Biological Process	GO:0042100	B cell proliferation	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:23728777
Biological Process	GO:0042100	B cell proliferation	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:25124037
Biological Process	GO:1990117	B cell receptor apoptotic signaling pathway	Nfkbiz	IDA		Mouse	PMID:23728777
Biological Process	GO:0050853	B cell receptor signaling pathway	Nfkbiz	IDA		Mouse	PMID:17367755
Biological Process	GO:0016049	cell growth	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:28740238
Biological Process	GO:0071345	cellular response to cytokine stimulus	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:26460049
Biological Process	GO:0071345	cellular response to cytokine stimulus	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:30224457
Biological Process	GO:0071345	cellular response to cytokine stimulus	Nfkbiz	IDA		Mouse	PMID:32144162
Biological Process	GO:0071345	cellular response to cytokine stimulus	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31622280
Biological Process	GO:0097398	cellular response to interleukin-17	Nfkbiz	IMP		Mouse	PMID:31164412
Biological Process	GO:0097398	cellular response to interleukin-17	Nfkbiz	IDA		Mouse	PMID:31853061
Biological Process	GO:0097398	cellular response to interleukin-17	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31622280
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:27129283
Biological Process	GO:0071310	cellular response to organic substance	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31853061
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:26019294
Biological Process	GO:0032602	chemokine production	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:15491998
Biological Process	GO:0032602	chemokine production	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:28740238
Biological Process	GO:0032602	chemokine production	Nfkbiz	IMP		Mouse	PMID:26776679
Biological Process	GO:0032602	chemokine production	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:32144162
Biological Process	GO:0006325	chromatin organization	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:18319258
Biological Process	GO:0006325	chromatin organization	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:25124037
Biological Process	GO:0006338	chromatin remodeling	Nfkbiz	IDA		Mouse	PMID:27129283
Biological Process	GO:0006338	chromatin remodeling	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:27129283
Biological Process	GO:0002544	chronic inflammatory response	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31853061
Biological Process	GO:0001816	cytokine production	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:28740238
Biological Process	GO:0001816	cytokine production	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790
Biological Process	GO:0001816	cytokine production	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:32144162
Biological Process	GO:0019221	cytokine-mediated signaling pathway	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:30224457
Biological Process	GO:0019221	cytokine-mediated signaling pathway	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31622280
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790
Biological Process	GO:1904019	epithelial cell apoptotic process	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:23453632
Biological Process	GO:0061436	establishment of skin barrier	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:28740238
Biological Process	GO:0097194	execution phase of apoptosis	Nfkbiz	IMP		Mouse	PMID:26776679
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:15491998
Biological Process	GO:0010467	gene expression	Nfkbiz	IDA		Mouse	PMID:15618216
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:18319258
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:18441309
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:20383124
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:23728777
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:26460049
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:27129283
Biological Process	GO:0010467	gene expression	Nfkbiz	IDA		Mouse	PMID:29934320
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:30224457
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:32144162
Biological Process	GO:0010467	gene expression	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31622280
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:26019294
Biological Process	GO:0016064	immunoglobulin mediated immune response	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:25124037
Biological Process	GO:0002377	immunoglobulin production	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:15491998
Biological Process	GO:0002377	immunoglobulin production	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790
Biological Process	GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:18441309
Biological Process	GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:28740238
Biological Process	GO:0006954	inflammatory response	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:15491998
Biological Process	GO:0006954	inflammatory response	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:18441309
Biological Process	GO:0006954	inflammatory response	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:23453632
Biological Process	GO:0006954	inflammatory response	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:26460049
Biological Process	GO:0006954	inflammatory response	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:28740238
Biological Process	GO:0006954	inflammatory response	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:30224457
Biological Process	GO:0006954	inflammatory response	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31622280
Biological Process	GO:0006954	inflammatory response	Nfkbiz	IDA		Mouse	PMID:11086164
Biological Process	GO:0090594	inflammatory response to wounding	Nfkbiz	IDA		Mouse	PMID:26776679
Biological Process	GO:0032613	interleukin-10 production	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:27129283
Biological Process	GO:0045190	isotype switching	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:25124037
Biological Process	GO:0045190	isotype switching	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790
Biological Process	GO:0032980	keratinocyte activation	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:15491998
Biological Process	GO:0030216	keratinocyte differentiation	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:26460049
Biological Process	GO:0043616	keratinocyte proliferation	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:26460049
Biological Process	GO:0043616	keratinocyte proliferation	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:30224457
Biological Process	GO:0002285	lymphocyte activation involved in immune response	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:23453632
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:27129283
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	Nfkbiz	IDA		Mouse	PMID:27129283
Biological Process	GO:0002317	plasma cell differentiation	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:25124037
Biological Process	GO:0050729	positive regulation of inflammatory response	NFKBIZ	IMP		Human	PMID:23071313
Biological Process	GO:2000321	positive regulation of T-helper 17 cell differentiation	Nfkbiz	IMP		Mouse	MGI:MGI:6142401\|PMID:25282160
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfkbiz	IDA		Mouse	PMID:27129283
Biological Process	GO:0050776	regulation of immune response	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:26019294
Biological Process	GO:0072718	response to cisplatin	Nfkbiz	IDA		Mouse	PMID:26776679
Biological Process	GO:0034097	response to cytokine	Nfkbiz	IMP		Mouse	PMID:26776679
Biological Process	GO:0051593	response to folic acid	Nfkbiz	IDA		Mouse	PMID:26776679
Biological Process	GO:0140459	response to Gram-positive bacterium	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:28740238
Biological Process	GO:0032496	response to lipopolysaccharide	Nfkbiz	IMP		Mouse	PMID:26776679
Biological Process	GO:0010033	response to organic substance	Nfkbiz	IDA		Mouse	PMID:29670287
Biological Process	GO:0010033	response to organic substance	Nfkbiz	IMP		Mouse	PMID:29670287
Biological Process	GO:0009410	response to xenobiotic stimulus	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31622280
Biological Process	GO:0043588	skin development	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:15491998
Biological Process	GO:0043588	skin development	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:26460049
Biological Process	GO:0043588	skin development	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:30224457
Biological Process	GO:0043588	skin development	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:31622280
Biological Process	GO:0098773	skin epidermis development	Nfkbiz	IMP	MGI:MGI:3525252	Mouse	PMID:15491998
Biological Process	GO:0048536	spleen development	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790
Biological Process	GO:0030217	T cell differentiation	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:26019294
Biological Process	GO:0030217	T cell differentiation	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790
Biological Process	GO:0002456	T cell mediated immunity	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790
Biological Process	GO:0050852	T cell receptor signaling pathway	Nfkbiz	IMP		Mouse	MGI:MGI:6142401\|PMID:25282160
Biological Process	GO:0045063	T-helper 1 cell differentiation	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790
Biological Process	GO:0072539	T-helper 17 cell differentiation	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:20383124
Biological Process	GO:0002224	toll-like receptor signaling pathway	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:23728777
Biological Process	GO:0002224	toll-like receptor signaling pathway	Nfkbiz	IDA		Mouse	PMID:23728777
Biological Process	GO:0002224	toll-like receptor signaling pathway	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:25124037
Biological Process	GO:0006366	transcription by RNA polymerase II	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:20383124
Biological Process	GO:0070897	transcription preinitiation complex assembly	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:18319258
Biological Process	GO:0032609	type II interferon production	Nfkbiz	IMP	MGI:MGI:5501251	Mouse	PMID:26019294
Biological Process	GO:0032609	type II interferon production	Nfkbiz	IMP	MGI:MGI:3046930	Mouse	PMID:31182790

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.