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Term Detail
GO term:T cell differentiation
Synonym: T cell development
Synonym: T-cell differentiation
Synonym: T lymphocyte differentiation
Synonym: T-lymphocyte differentiation
GO id:GO:0030217
Definition:The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
CommentsThis term was improved by GO_REF:0000022. It was moved. Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Number of paths to term: 24

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-aT cell activation
                                                                is-aalpha-beta T cell activation +
                                                                part-ofestablishment of T cell polarity
                                                                is-agamma-delta T cell activation +
                                                                is-amemory T cell activation +
                                                                negatively-regulatesnegative regulation of T cell activation +
                                                                positively-regulatespositive regulation of T cell activation +
                                                                regulatesregulation of T cell activation +
                                                                is-aT cell activation involved in immune response +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +
                                                                is-aT cell proliferation +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aleukocyte differentiation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aorgan development
                                        is-ahematopoietic or lymphoid organ development
                                                is-ahemopoiesis
                                                        part-ofleukocyte differentiation
                                                                is-alymphocyte differentiation
                                                                        is-aB cell differentiation +
                                                                        is-anatural killer cell differentiation +
                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                        regulatesregulation of lymphocyte differentiation +
                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                is-aalpha-beta T cell differentiation +
                                                                                is-acytotoxic T cell differentiation +
                                                                                is-aextrathymic T cell differentiation +
                                                                                is-agamma-delta T cell differentiation +
                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                part-ofpro-T cell differentiation +
                                                                                regulatesregulation of T cell differentiation +
                                                                                is-aregulatory T cell differentiation +
                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                is-aT cell differentiation in thymus +
                                                                                is-aT cell differentiation involved in immune response +
                                                                                part-ofT cell lineage commitment +
                                                                                part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-aimmune system development
                                                part-ofhematopoietic or lymphoid organ development
                                                        is-ahemopoiesis
                                                                part-ofleukocyte differentiation
                                                                        is-alymphocyte differentiation
                                                                                is-aB cell differentiation +
                                                                                is-anatural killer cell differentiation +
                                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                regulatesregulation of lymphocyte differentiation +
                                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                        is-aalpha-beta T cell differentiation +
                                                                                        is-acytotoxic T cell differentiation +
                                                                                        is-aextrathymic T cell differentiation +
                                                                                        is-agamma-delta T cell differentiation +
                                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                                        part-ofpro-T cell differentiation +
                                                                                        regulatesregulation of T cell differentiation +
                                                                                        is-aregulatory T cell differentiation +
                                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                                        is-aT cell differentiation in thymus +
                                                                                        is-aT cell differentiation involved in immune response +
                                                                                        part-ofT cell lineage commitment +
                                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-oforgan development
                                                is-ahematopoietic or lymphoid organ development
                                                        is-ahemopoiesis
                                                                part-ofleukocyte differentiation
                                                                        is-alymphocyte differentiation
                                                                                is-aB cell differentiation +
                                                                                is-anatural killer cell differentiation +
                                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                regulatesregulation of lymphocyte differentiation +
                                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                        is-aalpha-beta T cell differentiation +
                                                                                        is-acytotoxic T cell differentiation +
                                                                                        is-aextrathymic T cell differentiation +
                                                                                        is-agamma-delta T cell differentiation +
                                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                                        part-ofpro-T cell differentiation +
                                                                                        regulatesregulation of T cell differentiation +
                                                                                        is-aregulatory T cell differentiation +
                                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                                        is-aT cell differentiation in thymus +
                                                                                        is-aT cell differentiation involved in immune response +
                                                                                        part-ofT cell lineage commitment +
                                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aleukocyte differentiation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-ahematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                part-ofleukocyte differentiation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-alymphocyte differentiation
                                                                                        is-aB cell differentiation +
                                                                                        is-anatural killer cell differentiation +
                                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                        regulatesregulation of lymphocyte differentiation +
                                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                                is-aalpha-beta T cell differentiation +
                                                                                                is-acytotoxic T cell differentiation +
                                                                                                is-aextrathymic T cell differentiation +
                                                                                                is-agamma-delta T cell differentiation +
                                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                                part-ofpro-T cell differentiation +
                                                                                                regulatesregulation of T cell differentiation +
                                                                                                is-aregulatory T cell differentiation +
                                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                                is-aT cell differentiation in thymus +
                                                                                                is-aT cell differentiation involved in immune response +
                                                                                                part-ofT cell lineage commitment +
                                                                                                part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-alymphocyte differentiation
                                                                                        is-aB cell differentiation +
                                                                                        is-anatural killer cell differentiation +
                                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                        regulatesregulation of lymphocyte differentiation +
                                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                                is-aalpha-beta T cell differentiation +
                                                                                                is-acytotoxic T cell differentiation +
                                                                                                is-aextrathymic T cell differentiation +
                                                                                                is-agamma-delta T cell differentiation +
                                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                                part-ofpro-T cell differentiation +
                                                                                                regulatesregulation of T cell differentiation +
                                                                                                is-aregulatory T cell differentiation +
                                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                                is-aT cell differentiation in thymus +
                                                                                                is-aT cell differentiation involved in immune response +
                                                                                                part-ofT cell lineage commitment +
                                                                                                part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune system development
                                part-ofhematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                part-ofleukocyte differentiation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aleukocyte activation
                                is-alymphocyte activation
                                        is-alymphocyte differentiation
                                                is-aB cell differentiation +
                                                is-anatural killer cell differentiation +
                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                regulatesregulation of lymphocyte differentiation +
                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                        is-aalpha-beta T cell differentiation +
                                                        is-acytotoxic T cell differentiation +
                                                        is-aextrathymic T cell differentiation +
                                                        is-agamma-delta T cell differentiation +
                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                        positively-regulatespositive regulation of T cell differentiation +
                                                        part-ofpro-T cell differentiation +
                                                        regulatesregulation of T cell differentiation +
                                                        is-aregulatory T cell differentiation +
                                                        part-ofsomatic diversification of T cell receptor genes +
                                                        is-aT cell differentiation in thymus +
                                                        is-aT cell differentiation involved in immune response +
                                                        part-ofT cell lineage commitment +
                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aleukocyte activation
                                is-alymphocyte activation
                                        is-aT cell activation
                                                is-aalpha-beta T cell activation +
                                                part-ofestablishment of T cell polarity
                                                is-agamma-delta T cell activation +
                                                is-amemory T cell activation +
                                                negatively-regulatesnegative regulation of T cell activation +
                                                positively-regulatespositive regulation of T cell activation +
                                                regulatesregulation of T cell activation +
                                                is-aT cell activation involved in immune response +
                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                        is-aalpha-beta T cell differentiation +
                                                        is-acytotoxic T cell differentiation +
                                                        is-aextrathymic T cell differentiation +
                                                        is-agamma-delta T cell differentiation +
                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                        positively-regulatespositive regulation of T cell differentiation +
                                                        part-ofpro-T cell differentiation +
                                                        regulatesregulation of T cell differentiation +
                                                        is-aregulatory T cell differentiation +
                                                        part-ofsomatic diversification of T cell receptor genes +
                                                        is-aT cell differentiation in thymus +
                                                        is-aT cell differentiation involved in immune response +
                                                        part-ofT cell lineage commitment +
                                                        part-ofT cell selection +
                                                is-aT cell proliferation +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-alymphocyte differentiation
                                                                                        is-aB cell differentiation +
                                                                                        is-anatural killer cell differentiation +
                                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                        regulatesregulation of lymphocyte differentiation +
                                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                                is-aalpha-beta T cell differentiation +
                                                                                                is-acytotoxic T cell differentiation +
                                                                                                is-aextrathymic T cell differentiation +
                                                                                                is-agamma-delta T cell differentiation +
                                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                                part-ofpro-T cell differentiation +
                                                                                                regulatesregulation of T cell differentiation +
                                                                                                is-aregulatory T cell differentiation +
                                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                                is-aT cell differentiation in thymus +
                                                                                                is-aT cell differentiation involved in immune response +
                                                                                                part-ofT cell lineage commitment +
                                                                                                part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-alymphocyte differentiation
                                                                                        is-aB cell differentiation +
                                                                                        is-anatural killer cell differentiation +
                                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                        regulatesregulation of lymphocyte differentiation +
                                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                                is-aalpha-beta T cell differentiation +
                                                                                                is-acytotoxic T cell differentiation +
                                                                                                is-aextrathymic T cell differentiation +
                                                                                                is-agamma-delta T cell differentiation +
                                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                                part-ofpro-T cell differentiation +
                                                                                                regulatesregulation of T cell differentiation +
                                                                                                is-aregulatory T cell differentiation +
                                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                                is-aT cell differentiation in thymus +
                                                                                                is-aT cell differentiation involved in immune response +
                                                                                                part-ofT cell lineage commitment +
                                                                                                part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-alymphocyte differentiation
                                                                                        is-aB cell differentiation +
                                                                                        is-anatural killer cell differentiation +
                                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                        regulatesregulation of lymphocyte differentiation +
                                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                                is-aalpha-beta T cell differentiation +
                                                                                                is-acytotoxic T cell differentiation +
                                                                                                is-aextrathymic T cell differentiation +
                                                                                                is-agamma-delta T cell differentiation +
                                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                                part-ofpro-T cell differentiation +
                                                                                                regulatesregulation of T cell differentiation +
                                                                                                is-aregulatory T cell differentiation +
                                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                                is-aT cell differentiation in thymus +
                                                                                                is-aT cell differentiation involved in immune response +
                                                                                                part-ofT cell lineage commitment +
                                                                                                part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-alymphocyte differentiation
                                                                                        is-aB cell differentiation +
                                                                                        is-anatural killer cell differentiation +
                                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                        regulatesregulation of lymphocyte differentiation +
                                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                                is-aalpha-beta T cell differentiation +
                                                                                                is-acytotoxic T cell differentiation +
                                                                                                is-aextrathymic T cell differentiation +
                                                                                                is-agamma-delta T cell differentiation +
                                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                                part-ofpro-T cell differentiation +
                                                                                                regulatesregulation of T cell differentiation +
                                                                                                is-aregulatory T cell differentiation +
                                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                                is-aT cell differentiation in thymus +
                                                                                                is-aT cell differentiation involved in immune response +
                                                                                                part-ofT cell lineage commitment +
                                                                                                part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-aT cell activation
                                                                is-aalpha-beta T cell activation +
                                                                part-ofestablishment of T cell polarity
                                                                is-agamma-delta T cell activation +
                                                                is-amemory T cell activation +
                                                                negatively-regulatesnegative regulation of T cell activation +
                                                                positively-regulatespositive regulation of T cell activation +
                                                                regulatesregulation of T cell activation +
                                                                is-aT cell activation involved in immune response +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +
                                                                is-aT cell proliferation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aleukocyte differentiation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-aleukocyte differentiation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-ahematopoietic or lymphoid organ development
                                        is-ahemopoiesis
                                                part-ofleukocyte differentiation
                                                        is-alymphocyte differentiation
                                                                is-aB cell differentiation +
                                                                is-anatural killer cell differentiation +
                                                                negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                positively-regulatespositive regulation of lymphocyte differentiation +
                                                                regulatesregulation of lymphocyte differentiation +
                                                                is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-acytotoxic T cell differentiation +
                                                                        is-aextrathymic T cell differentiation +
                                                                        is-agamma-delta T cell differentiation +
                                                                        negatively-regulatesnegative regulation of T cell differentiation +
                                                                        positively-regulatespositive regulation of T cell differentiation +
                                                                        part-ofpro-T cell differentiation +
                                                                        regulatesregulation of T cell differentiation +
                                                                        is-aregulatory T cell differentiation +
                                                                        part-ofsomatic diversification of T cell receptor genes +
                                                                        is-aT cell differentiation in thymus +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        part-ofT cell lineage commitment +
                                                                        part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-aimmune system development
                                                        part-ofhematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-alymphocyte differentiation
                                                                                        is-aB cell differentiation +
                                                                                        is-anatural killer cell differentiation +
                                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                        regulatesregulation of lymphocyte differentiation +
                                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                                is-aalpha-beta T cell differentiation +
                                                                                                is-acytotoxic T cell differentiation +
                                                                                                is-aextrathymic T cell differentiation +
                                                                                                is-agamma-delta T cell differentiation +
                                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                                part-ofpro-T cell differentiation +
                                                                                                regulatesregulation of T cell differentiation +
                                                                                                is-aregulatory T cell differentiation +
                                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                                is-aT cell differentiation in thymus +
                                                                                                is-aT cell differentiation involved in immune response +
                                                                                                part-ofT cell lineage commitment +
                                                                                                part-ofT cell selection +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        is-ahematopoietic or lymphoid organ development
                                                                is-ahemopoiesis
                                                                        part-ofleukocyte differentiation
                                                                                is-alymphocyte differentiation
                                                                                        is-aB cell differentiation +
                                                                                        is-anatural killer cell differentiation +
                                                                                        negatively-regulatesnegative regulation of lymphocyte differentiation +
                                                                                        positively-regulatespositive regulation of lymphocyte differentiation +
                                                                                        regulatesregulation of lymphocyte differentiation +
                                                                                        is-aT cell differentiation [GO:0030217] (206 genes, 355 annotations)
                                                                                                is-aalpha-beta T cell differentiation +
                                                                                                is-acytotoxic T cell differentiation +
                                                                                                is-aextrathymic T cell differentiation +
                                                                                                is-agamma-delta T cell differentiation +
                                                                                                negatively-regulatesnegative regulation of T cell differentiation +
                                                                                                positively-regulatespositive regulation of T cell differentiation +
                                                                                                part-ofpro-T cell differentiation +
                                                                                                regulatesregulation of T cell differentiation +
                                                                                                is-aregulatory T cell differentiation +
                                                                                                part-ofsomatic diversification of T cell receptor genes +
                                                                                                is-aT cell differentiation in thymus +
                                                                                                is-aT cell differentiation involved in immune response +
                                                                                                part-ofT cell lineage commitment +
                                                                                                part-ofT cell selection +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory