Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nfe2l2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NFE2L2
- Mouse genes Nfe2l2
- Rat genes Nfe2l2
- Zfish genes nfe2l2a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfe2l2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	NFE2L2	IDA		Human	PMID:18554677
Molecular Function	GO:0003677	DNA binding	Nfe2l2	IDA		Mouse	PMID:14517290
Molecular Function	GO:0003677	DNA binding	Nfe2l2	IDA		Mouse	PMID:12220541
Molecular Function	GO:0003677	DNA binding	Nfe2l2	IDA		Mouse	PMID:15870285
Molecular Function	GO:0003677	DNA binding	nfe2l2a	IPI	UniProtKB:Q7T3H0	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	nfe2l2a	IPI	UniProtKB:Q6I6N0	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	nfe2l2a	IPI	UniProtKB:Q6NW89	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	nfe2l2a	IPI	UniProtKB:Q6I6N2	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	nfe2l2a	IDA		Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	nfe2l2a	IPI	UniProtKB:Q6I6N0	Zfish	PMID:15654768
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nfe2l2	IDA		Mouse	MGI:MGI:1332311\|PMID:10037736
Molecular Function	GO:0003700	DNA-binding transcription factor activity	NFE2L2	IDA		Human	PMID:17015834
Molecular Function	GO:0003700	DNA-binding transcription factor activity	NFE2L2	IDA		Human	PMID:20452972
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nfe2l2	IDA		Mouse	MGI:MGI:894855\|PMID:9240432
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nfe2l2	IDA		Mouse	PMID:12220541
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nfe2l2	IDA		Mouse	PMID:14517290
Molecular Function	GO:0003700	DNA-binding transcription factor activity	nfe2l2a	IGI	ZFIN:ZDB-GENE-040624-7	Zfish	PMID:15207702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	nfe2l2a	IGI	ZFIN:ZDB-GENE-040426-1280	Zfish	PMID:15207702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	nfe2l2a	IGI	ZFIN:ZDB-GENE-040624-9	Zfish	PMID:15207702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	nfe2l2a	IGI	ZFIN:ZDB-GENE-040426-2403	Zfish	PMID:15207702
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:15601839
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:16888629
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:17015834
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P10276	Human	PMID:18048326
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O15525	Human	PMID:18692475
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:18757741
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:19706542
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P29692-2	Human	PMID:21597468
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O15525	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O60675	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O15525	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P18848	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9ULX9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O15525	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P13805	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9BTA9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P18848	Human	PMID:26700459
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P11416	Human	PMID:28777872
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q60953	Human	PMID:28777872
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:29792731
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:A0A0C5B5G6	Human	PMID:29983246
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:31169361
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:31262713
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P13805	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O15525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O60341	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O60675	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P13805-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O00629	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O15144	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O15525	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O60519	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O60675	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O75478	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O75822	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:O94916	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P05412	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P10914	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P15036	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P15408	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P15976	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P18847	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P18848	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P19419	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P20226	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P27695	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P35638	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P40763	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P41212	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P43268	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P50549	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P52292	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P52564	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P53365	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P53539	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P53567	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P55210	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P62993	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:P78545	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q04206	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q04864	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q10587	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q13342	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q14145	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q6P1K2	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q6V702	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q96G23	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9NS37	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9UBW8	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9UJU2	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9UKB1	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9ULD4	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9ULX9	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	NFE2L2	IPI	UniProtKB:Q9Y297	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:P97474	Mouse	MGI:MGI:5800620\|PMID:27251288
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:Q8BWG8	Mouse	MGI:MGI:3688344\|PMID:15102471
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:Q9Z2X8	Mouse	MGI:MGI:3793517\|PMID:17903176
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:Q61827	Mouse	MGI:MGI:894855\|PMID:9240432
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:Q9Z2X8	Mouse	MGI:MGI:6451265\|PMID:31169361
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:Q9Z2X8	Mouse	MGI:MGI:5644008\|PMID:24366543
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:Q9Z2X8	Mouse	MGI:MGI:6368080\|PMID:15282312
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:Q9CPV5	Mouse	MGI:MGI:3688011\|PMID:11583586
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	PR:Q9Z2B5	Mouse	PMID:14517290
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	PR:Q9Z2X8	Mouse	PMID:24486487
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	PR:Q9Z2X8	Mouse	PMID:14517290
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	PR:Q9WU42	Mouse	PMID:15870285
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	PR:Q9Z2X8	Mouse	PMID:12193649
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	RGD:1310293	Rat	PMID:15870285\|RGD:5688307
Molecular Function	GO:0005515	protein binding	Nfe2l2	IPI	UniProtKB:Q8TD26	Rat	PMID:16314513\|RGD:8655528
Molecular Function	GO:0019904	protein domain specific binding	NFE2L2	IPI	UniProtKB:Q6P1K2	Human	PMID:11256947
Molecular Function	GO:0046982	protein heterodimerization activity	nfe2l2a	IPI	UniProtKB:Q6NW89	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	nfe2l2a	IPI	UniProtKB:Q6I6N2	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	nfe2l2a	IPI	UniProtKB:Q7T3H0	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	nfe2l2a	IPI	UniProtKB:Q6I6N0	Zfish	PMID:15654768
Molecular Function	GO:0046982	protein heterodimerization activity	nfe2l2a	IPI	UniProtKB:Q6I6N0	Zfish	PMID:15207702
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nfe2l2	IDA		Mouse	MGI:MGI:1332311\|PMID:10037736
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	NFE2L2	IPI	UniProtKB:Q13164	Human	PMID:23043106
Molecular Function	GO:0043565	sequence-specific DNA binding	NFE2L2	IDA		Human	PMID:20452972
Molecular Function	GO:0043565	sequence-specific DNA binding	Nfe2l2	IDA		Mouse	MGI:MGI:894855\|PMID:9240432
Molecular Function	GO:0043565	sequence-specific DNA binding	Nfe2l2	IDA		Rat	PMID:19735445\|RGD:6893328
Molecular Function	GO:0000976	transcription cis-regulatory region binding	NFE2L2	IDA		Human	PMID:20452972
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Nfe2l2	IDA		Mouse	MGI:MGI:894855\|PMID:9240432
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Nfe2l2	IDA		Rat	PMID:16314513\|RGD:8655528
Molecular Function	GO:0000976	transcription cis-regulatory region binding	nfe2l2a	IDA		Zfish	PMID:24652768
Molecular Function	GO:0001221	transcription coregulator binding	Nfe2l2	IPI	UniProtKB:Q6IRI7	Rat	PMID:16314513\|RGD:8655528
Molecular Function	GO:0008134	transcription factor binding	Nfe2l2	IPI	UniProtKB:O95718-3	Mouse	MGI:MGI:5897755\|PMID:17920186
Cellular Component	GO:0005813	centrosome	NFE2L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000785	chromatin	Nfe2l2	IDA		Mouse	MGI:MGI:4850200\|PMID:20978343
Cellular Component	GO:0005737	cytoplasm	NFE2L2	IDA		Human	PMID:15601839
Cellular Component	GO:0005737	cytoplasm	NFE2L2	IDA		Human	PMID:22492997
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IDA		Mouse	MGI:MGI:4850200\|PMID:20978343
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IDA		Mouse	MGI:MGI:3793517\|PMID:17903176
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IDA		Mouse	MGI:MGI:5897755\|PMID:17920186
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IDA		Mouse	MGI:MGI:5616326\|PMID:14978030
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IDA		Mouse	MGI:MGI:6368086\|PMID:15367669
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IPI	PR:Q9Z2X8	Mouse	PMID:14517290
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IDA		Rat	PMID:18787991\|RGD:5134971
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IDA		Rat	PMID:26637559\|RGD:11344212
Cellular Component	GO:0005737	cytoplasm	Nfe2l2	IDA		Rat	PMID:31089916\|RGD:155882543
Cellular Component	GO:0005737	cytoplasm	nfe2l2a	IDA		Zfish	PMID:22174413
Cellular Component	GO:0005829	cytosol	NFE2L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	NFE2L2	IDA		Human	PMID:23043106
Cellular Component	GO:0005829	cytosol	Nfe2l2	IDA		Mouse	MGI:MGI:5487481\|PMID:23043106
Cellular Component	GO:0005794	Golgi apparatus	NFE2L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NFE2L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NFE2L2	IDA		Human	PMID:15601839
Cellular Component	GO:0005634	nucleus	NFE2L2	IDA		Human	PMID:18202225
Cellular Component	GO:0005634	nucleus	NFE2L2	IDA		Human	PMID:18554677
Cellular Component	GO:0005634	nucleus	NFE2L2	IDA		Human	PMID:22492997
Cellular Component	GO:0005634	nucleus	NFE2L2	IDA		Human	PMID:23043106
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Mouse	MGI:MGI:5616326\|PMID:14978030
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Mouse	MGI:MGI:5897755\|PMID:17920186
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Mouse	MGI:MGI:5487481\|PMID:23043106
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Mouse	PMID:14517290
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Mouse	PMID:15870285
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Mouse	PMID:15087497
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Rat	PMID:16314513\|RGD:8655528
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Rat	PMID:18787991\|RGD:5134971
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Rat	PMID:20554019\|RGD:11049539
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Rat	PMID:26637559\|RGD:11344212
Cellular Component	GO:0005634	nucleus	Nfe2l2	IDA		Rat	PMID:31089916\|RGD:155882543
Cellular Component	GO:0005634	nucleus	nfe2l2a	IDA		Zfish	PMID:22174413
Cellular Component	GO:0005886	plasma membrane	NFE2L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032993	protein-DNA complex	Nfe2l2	IDA		Mouse	MGI:MGI:2677605\|PMID:14517290
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NFE2L2	IPI		Human	PMID:23661758
Cellular Component	GO:0005667	transcription regulator complex	nfe2l2a	IDA		Zfish	PMID:15207702
Biological Process	GO:0046223	aflatoxin catabolic process	Nfe2l2	IMP		Rat	PMID:27071940\|RGD:12910550
Biological Process	GO:0007568	aging	Nfe2l2	IEP		Rat	PMID:16155909\|RGD:11049544
Biological Process	GO:0045454	cell redox homeostasis	NFE2L2	IMP		Human	PMID:29018201
Biological Process	GO:0045454	cell redox homeostasis	Nfe2l2	IMP		Mouse	MGI:MGI:5616326\|PMID:14978030
Biological Process	GO:0045454	cell redox homeostasis	Nfe2l2	IMP		Rat	PMID:16314513\|RGD:8655528
Biological Process	GO:1904385	cellular response to angiotensin	Nfe2l2	IDA		Rat	PMID:26637559\|RGD:11344212
Biological Process	GO:0071280	cellular response to copper ion	Nfe2l2	IMP	MGI:MGI:2385925	Mouse	PMID:24462598
Biological Process	GO:0071498	cellular response to fluid shear stress	NFE2L2	IDA		Human	PMID:25190803
Biological Process	GO:0042149	cellular response to glucose starvation	Nfe2l2	IMP		Mouse	MGI:MGI:5616326\|PMID:14978030
Biological Process	GO:0070301	cellular response to hydrogen peroxide	NFE2L2	IMP		Human	PMID:23043106
Biological Process	GO:0071456	cellular response to hypoxia	Nfe2l2	IEP		Rat	PMID:23904790\|RGD:10412703
Biological Process	GO:0071499	cellular response to laminar fluid shear stress	NFE2L2	IMP		Human	PMID:23043106
Biological Process	GO:0034599	cellular response to oxidative stress	Nfe2l2	IDA		Mouse	MGI:MGI:4850200\|PMID:20978343
Biological Process	GO:0034599	cellular response to oxidative stress	Nfe2l2	IDA		Mouse	MGI:MGI:894855\|PMID:9240432
Biological Process	GO:0034599	cellular response to oxidative stress	Nfe2l2	IMP	MGI:MGI:2385925	Mouse	PMID:20978266
Biological Process	GO:0034599	cellular response to oxidative stress	nfe2l2a	IMP	ZFIN:ZDB-GENO-210506-5	Zfish	PMID:31858786
Biological Process	GO:0034599	cellular response to oxidative stress	nfe2l2a	IMP	ZFIN:ZDB-GENO-210506-3	Zfish	PMID:31858786
Biological Process	GO:0034599	cellular response to oxidative stress	nfe2l2a	IMP	ZFIN:ZDB-MRPHLNO-050603-1	Zfish	PMID:27671773
Biological Process	GO:0071379	cellular response to prostaglandin stimulus	nfe2l2a	IMP	ZFIN:ZDB-MRPHLNO-050603-1	Zfish	PMID:19001094
Biological Process	GO:0071379	cellular response to prostaglandin stimulus	nfe2l2a	IGI	ZFIN:ZDB-GENE-080508-1	Zfish	PMID:19001094
Biological Process	GO:0071356	cellular response to tumor necrosis factor	NFE2L2	IMP		Human	PMID:18202225
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Nfe2l2	IEP		Rat	PMID:29373037\|RGD:26923905
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Nfe2l2	IMP	MGI:MGI:2386080	Mouse	PMID:24486487
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	nfe2l2a	IMP	ZFIN:ZDB-MRPHLNO-050603-1	Zfish	PMID:19001094
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	nfe2l2a	IGI	ZFIN:ZDB-GENE-030131-556	Zfish	PMID:19001094
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	Nfe2l2	IDA		Mouse	PMID:14517290
Biological Process	GO:0006954	inflammatory response	Nfe2l2	IMP	MGI:MGI:2385925	Mouse	PMID:24486487
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	Nfe2l2	IMP		Rat	PMID:23453443\|RGD:10412713
Biological Process	GO:1900038	negative regulation of cellular response to hypoxia	Nfe2l2	IMP		Rat	PMID:24048861\|RGD:10412727
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	NFE2L2	IMP		Human	PMID:23043106
Biological Process	GO:1902037	negative regulation of hematopoietic stem cell differentiation	Nfe2l2	IMP		Mouse	MGI:MGI:5476857\|PMID:23434824
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	NFE2L2	IGI	UniProtKB:Q99497	Human	PMID:22492997
Biological Process	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	NFE2L2	IMP		Human	PMID:23043106
Biological Process	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	Nfe2l2	IMP		Rat	PMID:23413426\|RGD:10412715
Biological Process	GO:0036499	PERK-mediated unfolded protein response	Nfe2l2	IDA		Mouse	MGI:MGI:2677605\|PMID:14517290
Biological Process	GO:0045766	positive regulation of angiogenesis	Nfe2l2	IMP		Rat	PMID:23904790\|RGD:10412703
Biological Process	GO:0030194	positive regulation of blood coagulation	Nfe2l2	IMP		Mouse	MGI:MGI:4850200\|PMID:20978343
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	Nfe2l2	IMP		Rat	PMID:23904790\|RGD:10412703
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfe2l2	IGI	MGI:MGI:1858732	Mouse	PMID:15087497
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfe2l2	IDA		Mouse	PMID:14517290
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfe2l2	IDA		Mouse	PMID:15870285
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	nfe2l2a	IGI	ZFIN:ZDB-GENE-040426-1280	Zfish	PMID:15207702
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	nfe2l2a	IGI	ZFIN:ZDB-GENE-040624-7	Zfish	PMID:15207702
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	nfe2l2a	IGI	ZFIN:ZDB-GENE-040624-9	Zfish	PMID:15207702
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	nfe2l2a	IGI	ZFIN:ZDB-GENE-040426-2403	Zfish	PMID:15207702
Biological Process	GO:0010628	positive regulation of gene expression	NFE2L2	IGI	UniProtKB:Q99497	Human	PMID:22492997
Biological Process	GO:0010628	positive regulation of gene expression	NFE2L2	IMP		Human	PMID:27155659
Biological Process	GO:0010628	positive regulation of gene expression	Nfe2l2	IGI	UniProtKB:O54790	Mouse	MGI:MGI:5616326\|PMID:14978030
Biological Process	GO:0010628	positive regulation of gene expression	Nfe2l2	IMP		Rat	PMID:26637559\|RGD:11344212
Biological Process	GO:0046326	positive regulation of glucose import	Nfe2l2	IDA		Mouse	MGI:MGI:5619938\|PMID:24024172
Biological Process	GO:1903788	positive regulation of glutathione biosynthetic process	Nfe2l2	IMP		Mouse	MGI:MGI:5616326\|PMID:14978030
Biological Process	GO:0010976	positive regulation of neuron projection development	Nfe2l2	IMP		Rat	PMID:19762340\|RGD:10412684
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	Nfe2l2	IMP		Mouse	MGI:MGI:4850200\|PMID:20978343
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NFE2L2	IDA		Human	PMID:17015834
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NFE2L2	IMP		Human	PMID:18202225
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NFE2L2	IMP		Human	PMID:25190803
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfe2l2	IDA		Mouse	MGI:MGI:1332311\|PMID:10037736
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfe2l2	IMP		Mouse	MGI:MGI:5616326\|PMID:14978030
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfe2l2	IDA		Mouse	MGI:MGI:5905273\|PMID:15574414
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfe2l2	IDA		Mouse	MGI:MGI:4850200\|PMID:20978343
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfe2l2	IDA		Mouse	MGI:MGI:4943400\|PMID:17015834
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfe2l2	IMP	MGI:MGI:2385925	Mouse	PMID:24462598
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfe2l2	IMP		Rat	PMID:16314513\|RGD:8655528
Biological Process	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	NFE2L2	IMP		Human	PMID:24844779
Biological Process	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	NFE2L2	IMP		Human	PMID:23043106
Biological Process	GO:0010499	proteasomal ubiquitin-independent protein catabolic process	NFE2L2	IDA		Human	PMID:19424503
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	NFE2L2	IDA		Human	PMID:15983046
Biological Process	GO:0016567	protein ubiquitination	NFE2L2	IDA		Human	PMID:15983046
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	NFE2L2	EXP		Human	PMID:34299054
Biological Process	GO:0006355	regulation of DNA-templated transcription	Nfe2l2	IDA		Mouse	PMID:12220541
Biological Process	GO:0006355	regulation of DNA-templated transcription	nfe2l2a	IDA		Zfish	PMID:24652768
Biological Process	GO:0006355	regulation of DNA-templated transcription	nfe2l2a	IMP	ZFIN:ZDB-MRPHLNO-050603-1	Zfish	PMID:27671773
Biological Process	GO:0045995	regulation of embryonic development	Nfe2l2	IGI	MGI:MGI:1858732	Mouse	PMID:15087497
Biological Process	GO:0045088	regulation of innate immune response	Nfe2l2	IMP		Mouse	MGI:MGI:3622037\|PMID:16585964
Biological Process	GO:2000121	regulation of removal of superoxide radicals	Nfe2l2	IMP		Mouse	MGI:MGI:4850200\|PMID:20978343
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Nfe2l2	IMP		Mouse	MGI:MGI:5616326\|PMID:14978030
Biological Process	GO:0002931	response to ischemia	Nfe2l2	IEP		Rat	PMID:31089916\|RGD:155882543
Biological Process	GO:0010226	response to lithium ion	Nfe2l2	IEP		Rat	PMID:25224036\|RGD:26923906
Biological Process	GO:0010033	response to organic substance	Nfe2l2	IDA		Mouse	PMID:29670287
Biological Process	GO:0006979	response to oxidative stress	nfe2l2a	IMP	ZFIN:ZDB-GENO-121120-1	Zfish	PMID:22949501
Biological Process	GO:0009410	response to xenobiotic stimulus	Nfe2l2	IEP		Rat	PMID:29091898\|RGD:15090820

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.