Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DAPK1
  • Mouse genes Dapk1
  • Rat genes Dapk1
  • Zfish genes dapk1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dapk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	DAPK1	IDA		Human	PMID:10629061
Molecular Function	GO:0005524	ATP binding	Dapk1	IDA		Mouse	MGI:MGI:2152512|PMID:11485996
Molecular Function	GO:0005516	calmodulin binding	DAPK1	IDA		Human	PMID:10629061
Molecular Function	GO:0005516	calmodulin binding	Dapk1	IDA		Mouse	MGI:MGI:2152512|PMID:11485996
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	DAPK1	IDA		Human	PMID:10629061
Molecular Function	GO:0042802	identical protein binding	DAPK1	IPI	UniProtKB:P53355	Human	PMID:19180116
Molecular Function	GO:0042802	identical protein binding	DAPK1	IPI	UniProtKB:P53355	Human	PMID:19712061
Molecular Function	GO:0042802	identical protein binding	DAPK1	IPI	UniProtKB:P53355	Human	PMID:21738225
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:P27361	Human	PMID:15616583
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:O75340	Human	PMID:16132846
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q14457	Human	PMID:19180116
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q38SD2	Human	PMID:19712061
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q5S007	Human	PMID:19712061
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:P63151	Human	PMID:20220139
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q9Y2M5	Human	PMID:20389280
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:P14618	Human	PMID:21725354
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:P14618-1	Human	PMID:21725354
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:P27361	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:O95816	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:O95185	Human	PMID:27068745
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q96C12	Human	PMID:28169274
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:O95816	Human	PMID:29513927
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q9UHB6	Human	PMID:29513927
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q9UNE7	Human	PMID:29513927
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:P63151	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q9UHB6	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	DAPK1	IPI	UniProtKB:Q9UNE7	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Dapk1	IPI	UniProtKB:Q01097	Mouse	MGI:MGI:4457467|PMID:20141836
Molecular Function	GO:0005515	protein binding	Dapk1	IPI	PR:Q3TNL8	Mouse	PMID:20053891
Molecular Function	GO:0004672	protein kinase activity	DAPK1	IDA		Human	PMID:12730201
Molecular Function	GO:0004672	protein kinase activity	DAPK1	IDA		Human	PMID:7828849
Molecular Function	GO:0004672	protein kinase activity	Dapk1	IDA		Mouse	PMID:20053891
Molecular Function	GO:0017075	syntaxin-1 binding	DAPK1	IPI	UniProtKB:Q16623	Human	PMID:12730201
Cellular Component	GO:0015629	actin cytoskeleton	DAPK1	IDA		Human	PMID:10629061
Cellular Component	GO:0005737	cytoplasm	DAPK1	IDA		Human	PMID:12730201
Cellular Component	GO:0005737	cytoplasm	Dapk1	IDA		Mouse	PMID:15010850
Cellular Component	GO:1990722	DAPK1-calmodulin complex	DAPK1	IPI		Human	PMID:20103772
Cellular Component	GO:0098978	glutamatergic synapse	Dapk1	IPI		Mouse	PMID:20141836
Cellular Component	GO:0098978	glutamatergic synapse	Dapk1	IDA		Mouse	PMID:20141836
Cellular Component	GO:0005886	plasma membrane	DAPK1	IDA		Human	PMID:12730201
Cellular Component	GO:0014069	postsynaptic density	Dapk1	IDA		Mouse	PMID:20141836
Cellular Component	GO:0014069	postsynaptic density	Dapk1	IPI		Mouse	PMID:20141836
Biological Process	GO:0006915	apoptotic process	DAPK1	IGI	UniProtKB:P01579	Human	PMID:7828849
Biological Process	GO:0006915	apoptotic process	DAPK1	IMP		Human	PMID:10629061
Biological Process	GO:0097190	apoptotic signaling pathway	DAPK1	IMP		Human	PMID:7828849
Biological Process	GO:0071447	cellular response to hydroperoxide	DAPK1	IMP		Human	PMID:22095288
Biological Process	GO:0071346	cellular response to type II interferon	DAPK1	IDA		Human	PMID:18995835
Biological Process	GO:0071346	cellular response to type II interferon	Dapk1	IMP		Mouse	MGI:MGI:5466658|PMID:23071094
Biological Process	GO:0002357	defense response to tumor cell	DAPK1	IMP		Human	PMID:30429596
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Dapk1	IMP	MGI:MGI:3052030	Mouse	PMID:15010850
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Dapk1	IGI	MGI:MGI:3042776	Mouse	PMID:20053891
Biological Process	GO:0035556	intracellular signal transduction	DAPK1	IDA		Human	PMID:10629061
Biological Process	GO:0035556	intracellular signal transduction	Dapk1	IDA		Mouse	MGI:MGI:2152512|PMID:11485996
Biological Process	GO:0043066	negative regulation of apoptotic process	Dapk1	IMP		Mouse	MGI:MGI:2152512|PMID:11485996
Biological Process	GO:0017148	negative regulation of translation	DAPK1	IDA		Human	PMID:18995835
Biological Process	GO:0043065	positive regulation of apoptotic process	DAPK1	IMP		Human	PMID:10629061
Biological Process	GO:1904094	positive regulation of autophagic cell death	DAPK1	IMP		Human	PMID:11980920
Biological Process	GO:0010508	positive regulation of autophagy	DAPK1	IMP		Human	PMID:22095288
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	DAPK1	IDA		Human	PMID:16132846
Biological Process	GO:0046777	protein autophosphorylation	DAPK1	IDA		Human	PMID:10629061
Biological Process	GO:0046777	protein autophosphorylation	DAPK1	IDA		Human	PMID:12730201
Biological Process	GO:0006468	protein phosphorylation	DAPK1	IDA		Human	PMID:10629061
Biological Process	GO:0006468	protein phosphorylation	Dapk1	IDA		Mouse	MGI:MGI:2152512|PMID:11485996
Biological Process	GO:2000310	regulation of NMDA receptor activity	Dapk1	IMP		Mouse	MGI:MGI:4457467|PMID:20141836
Biological Process	GO:0002834	regulation of response to tumor cell	DAPK1	IDA		Human	PMID:11573098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern