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Term Detail
GO term:calmodulin-dependent protein kinase activity
Synonym: ATP:caldesmon O-phosphotransferase activity
Synonym: ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity
Synonym: Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity
Synonym: Ca2+/calmodulin-dependent protein kinase 1 activity
Synonym: Ca2+/calmodulin-dependent protein kinase activity
Synonym: Ca2+/calmodulin-dependent protein kinase II activity
Synonym: Ca2+/calmodulin-dependent protein kinase IV activity
Synonym: Ca2+/calmodulin-dependent protein kinase kinase activity
Synonym: Ca2+/calmodulin-dependent protein kinase kinase beta activity
Synonym: Ca2+/CaM-dependent kinase activity
Synonym: calcium- and calmodulin-dependent protein kinase activity
Synonym: calcium/calmodulin-dependent protein kinase activity
Synonym: calcium/calmodulin-dependent protein kinase type II activity
Synonym: caldesmon kinase (phosphorylating) activity
Synonym: calmodulin-dependent kinase II activity
Synonym: calmodulin-dependent protein kinase I activity
Synonym: calmodulin regulated protein kinase activity
Synonym: CaMKI
Synonym: CaMKII
Synonym: CaM kinase activity
Synonym: CaM kinase II activity
Synonym: CaMKIV
Synonym: CaMKKalpha
Synonym: CaMKKbeta
Synonym: CAM PKII
Synonym: CaM-regulated serine/threonine kinase activity
Synonym: microtubule-associated protein 2 kinase activity
Synonym: multifunctional calcium- and calmodulin-regulated protein kinase activity
Synonym: multifunctional calcium/calmodulin regulated protein kinase activity
Synonym: STK20
GO id:GO:0004683
Definition:Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring phosphorus-containing groups
                                        is-akinase activity
                                                is-aprotein kinase activity
                                                        is-aprotein serine/threonine kinase activity
                                                                is-a3-phosphoinositide-dependent protein kinase activity
                                                                is-aAMP-activated protein kinase activity
                                                                is-acalcium-dependent protein serine/threonine kinase activity +
                                                                is-acalmodulin-dependent protein kinase activity [GO:0004683] (25 genes, 33 annotations)
                                                                        is-aelongation factor-2 kinase activity
                                                                        is-amyosin heavy chain kinase activity
                                                                        is-aphosphorylase kinase activity
                                                                is-acyclic nucleotide-dependent protein kinase activity +
                                                                is-acyclin-dependent protein serine/threonine kinase activity
                                                                is-aDNA-dependent protein kinase activity
                                                                is-aeukaryotic translation initiation factor 2alpha kinase activity
                                                                is-aFas-activated serine/threonine kinase activity
                                                                is-aG-protein coupled receptor kinase activity
                                                                is-aGoodpasture-antigen-binding protein kinase activity
                                                                is-aGTP-dependent protein kinase activity
                                                                is-ahistone serine kinase activity +
                                                                is-ahistone threonine kinase activity +
                                                                is-aIkappaB kinase activity
                                                                is-amyosin light chain kinase activity
                                                                is-aprotein kinase C activity +
                                                                is-areceptor signaling protein serine/threonine kinase activity +
                                                                is-aRho-dependent protein serine/threonine kinase activity
                                                                is-aribosomal protein S6 kinase activity
                                                                is-aRNA polymerase II carboxy-terminal domain kinase activity
                                                                is-atransmembrane receptor protein serine/threonine kinase activity +


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring phosphorus-containing groups
                                        is-aphosphotransferase activity, alcohol group as acceptor
                                                is-aprotein kinase activity
                                                        is-aprotein serine/threonine kinase activity
                                                                is-a3-phosphoinositide-dependent protein kinase activity
                                                                is-aAMP-activated protein kinase activity
                                                                is-acalcium-dependent protein serine/threonine kinase activity +
                                                                is-acalmodulin-dependent protein kinase activity [GO:0004683] (25 genes, 33 annotations)
                                                                        is-aelongation factor-2 kinase activity
                                                                        is-amyosin heavy chain kinase activity
                                                                        is-aphosphorylase kinase activity
                                                                is-acyclic nucleotide-dependent protein kinase activity +
                                                                is-acyclin-dependent protein serine/threonine kinase activity
                                                                is-aDNA-dependent protein kinase activity
                                                                is-aeukaryotic translation initiation factor 2alpha kinase activity
                                                                is-aFas-activated serine/threonine kinase activity
                                                                is-aG-protein coupled receptor kinase activity
                                                                is-aGoodpasture-antigen-binding protein kinase activity
                                                                is-aGTP-dependent protein kinase activity
                                                                is-ahistone serine kinase activity +
                                                                is-ahistone threonine kinase activity +
                                                                is-aIkappaB kinase activity
                                                                is-amyosin light chain kinase activity
                                                                is-aprotein kinase C activity +
                                                                is-areceptor signaling protein serine/threonine kinase activity +
                                                                is-aRho-dependent protein serine/threonine kinase activity
                                                                is-aribosomal protein S6 kinase activity
                                                                is-aRNA polymerase II carboxy-terminal domain kinase activity
                                                                is-atransmembrane receptor protein serine/threonine kinase activity +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory