Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Chrna7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CHRFAM7A,CHRNA7
- Mouse genes Chrna7
- Rat genes Chrna7
- Zfish genes chrna7a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chrna7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042166	acetylcholine binding	CHRNA7	IDA		Human	PMID:8145738
Molecular Function	GO:0042166	acetylcholine binding	Chrna7	IDA		Rat	PMID:11297818\|RGD:1643016
Molecular Function	GO:0042166	acetylcholine binding	Chrna7	IMP		Rat	PMID:16186249\|RGD:1600971
Molecular Function	GO:0015464	acetylcholine receptor activity	CHRNA7	IDA		Human	PMID:8906617
Molecular Function	GO:0015464	acetylcholine receptor activity	chrna7a	IDA		Zfish	PMID:22580045
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA7	IDA		Human	PMID:12508119
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA7	IDA		Human	PMID:18387948
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA7	IDA		Human	PMID:21718690
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA7	IDA		Human	PMID:8145738
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA7	IDA		Human	PMID:8906617
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IDA		Mouse	PMID:9495872
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:9364063
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:11834293
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IMP		Mouse	PMID:9037516
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IDA		Rat	PMID:11222635\|RGD:8554133
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IMP		Rat	PMID:11259617\|RGD:8549520
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IMP		Rat	PMID:11297818\|RGD:1643016
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IDA		Rat	PMID:12069582\|RGD:727702
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IMP		Rat	PMID:15760934\|RGD:8554382
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IMP		Rat	PMID:16186249\|RGD:1600971
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrna7	IDA		Rat	PMID:21540349\|RGD:12790638
Molecular Function	GO:0008179	adenylate cyclase binding	Chrna7	IPI	RGD:2035	Rat	PMID:12748066\|RGD:1600980
Molecular Function	GO:0001540	amyloid-beta binding	CHRNA7	IPI	UniProtKB:P05067:PRO_0000000092	Human	PMID:10681545
Molecular Function	GO:0051117	ATPase binding	Chrna7	IDA		Rat	PMID:22593058\|RGD:7205692
Molecular Function	GO:0017081	chloride channel regulator activity	CHRNA7	IDA		Human	PMID:8145738
Molecular Function	GO:0005216	monoatomic ion channel activity	CHRNA7	IDA		Human	PMID:17898229
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:P05067	Human	PMID:10681545
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:P05067:PRO_0000000092	Human	PMID:10681545
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:P55000	Human	PMID:26905431
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:Q86Y78	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:P27824	Human	PMID:32783947
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:Q09028	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:Q13573	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:Q8N5J2-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:Q9NSI6-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CHRNA7	IPI	UniProtKB:Q9UBU7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Chrna7	IPI	PR:Q8BLC3	Mouse	PMID:19246390
Molecular Function	GO:0005515	protein binding	Chrna7	IPI	UniProtKB:Q9WVC2	Mouse	PMID:11906696
Molecular Function	GO:0005515	protein binding	Chrna7	IPI	UniProtKB:P60615	Rat	PMID:10627589\|RGD:10047285
Molecular Function	GO:0005515	protein binding	Chrna7	IPI	UniProtKB:P05067:PRO_0000000092	Rat	PMID:10681545\|RGD:14397579
Molecular Function	GO:0005515	protein binding	Chrna7	IPI	RGD:2123	Rat	PMID:17507554\|RGD:4110128
Molecular Function	GO:0005515	protein binding	Chrna7	IPI	UniProtKB:Q7Z2K8	Rat	PMID:24350810\|RGD:150521630
Molecular Function	GO:0005515	protein binding	Chrna7	IPI	UniProtKB:P05067:PRO_0000000092	Rat	PMID:27460145\|RGD:21201255
Molecular Function	GO:0042803	protein homodimerization activity	CHRNA7	IDA		Human	PMID:8145738
Molecular Function	GO:0019901	protein kinase binding	Chrna7	IPI	RGD:2939	Rat	PMID:12244045\|RGD:633056
Molecular Function	GO:0097110	scaffold protein binding	Chrna7	IDA		Rat	PMID:22593058\|RGD:7205692
Molecular Function	GO:0015643	toxic substance binding	CHRNA7	IDA		Human	PMID:12508119
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Chrna7	EXP		Rat	PMID:15044058\|RGD:1600975
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Chrna7	IDA		Rat	PMID:15044058\|RGD:1600975
Cellular Component	GO:0005892	acetylcholine-gated channel complex	CHRNA7	IDA		Human	PMID:8906617
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrna7	IPI		Mouse	MGI:MGI:6810690\|PMID:22039094
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrna7	IDA		Rat	PMID:11259617\|RGD:8549520
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrna7	IDA		Rat	PMID:12645078\|RGD:704420
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrna7	IDA		Rat	PMID:21540349\|RGD:12790638
Cellular Component	GO:0005892	acetylcholine-gated channel complex	chrna7a	IDA		Zfish	PMID:22580045
Cellular Component	GO:0016324	apical plasma membrane	Chrna7	IDA		Mouse	PMID:16033766
Cellular Component	GO:0032279	asymmetric synapse	Chrna7	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0030673	axolemma	Chrna7	IDA		Mouse	PMID:18458158
Cellular Component	GO:0030424	axon	Chrna7	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0030424	axon	Chrna7	IDA		Rat	PMID:12645078\|RGD:704420
Cellular Component	GO:0098981	cholinergic synapse	Chrna7	IDA		Mouse	PMID:12079404
Cellular Component	GO:0098981	cholinergic synapse	Chrna7	EXP		Rat	PMID:15044058\|RGD:1600975
Cellular Component	GO:0098981	cholinergic synapse	Chrna7	IDA		Rat	PMID:15044058\|RGD:1600975
Cellular Component	GO:0005737	cytoplasm	Chrna7	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0030425	dendrite	Chrna7	IDA		Rat	PMID:11297818\|RGD:1643016
Cellular Component	GO:0030425	dendrite	Chrna7	IDA		Rat	PMID:15179037\|RGD:151676718
Cellular Component	GO:0043198	dendritic shaft	Chrna7	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0043197	dendritic spine	Chrna7	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0009897	external side of plasma membrane	Chrna7	IDA		Mouse	PMID:15963492
Cellular Component	GO:0098690	glycinergic synapse	Chrna7	EXP		Rat	PMID:21762741\|RGD:13702307
Cellular Component	GO:0098690	glycinergic synapse	Chrna7	IDA		Rat	PMID:21762741\|RGD:13702307
Cellular Component	GO:0030426	growth cone	Chrna7	IDA		Rat	PMID:12645078\|RGD:704420
Cellular Component	GO:0016020	membrane	Chrna7	IDA		Mouse	PMID:11834293
Cellular Component	GO:0016020	membrane	Chrna7	IDA		Mouse	PMID:19246390
Cellular Component	GO:0045121	membrane raft	Chrna7	IDA		Rat	PMID:12748066\|RGD:1600980
Cellular Component	GO:0043025	neuronal cell body	Chrna7	IDA		Rat	PMID:11297818\|RGD:1643016
Cellular Component	GO:0043025	neuronal cell body	Chrna7	IDA		Rat	PMID:12645078\|RGD:704420
Cellular Component	GO:0043025	neuronal cell body	Chrna7	IDA		Rat	PMID:15179037\|RGD:151676718
Cellular Component	GO:0005886	plasma membrane	CHRNA7	IDA		Human	PMID:12508119
Cellular Component	GO:0005886	plasma membrane	CHRNA7	IDA		Human	PMID:16280133
Cellular Component	GO:0005886	plasma membrane	CHRNA7	IDA		Human	PMID:21718690
Cellular Component	GO:0005886	plasma membrane	CHRNA7	IDA		Human	PMID:27789755
Cellular Component	GO:0005886	plasma membrane	Chrna7	IDA		Rat	PMID:12748066\|RGD:1600980
Cellular Component	GO:0044853	plasma membrane raft	Chrna7	IDA		Rat	PMID:21540349\|RGD:12790638
Cellular Component	GO:0014069	postsynaptic density	Chrna7	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0045211	postsynaptic membrane	Chrna7	IEP		Mouse	PMID:24607281
Cellular Component	GO:0045211	postsynaptic membrane	Chrna7	IDA		Mouse	PMID:24607281
Cellular Component	GO:0045211	postsynaptic membrane	Chrna7	IDA		Rat	PMID:24607281\|RGD:13702281
Cellular Component	GO:0099634	postsynaptic specialization membrane	Chrna7	IDA		Mouse	PMID:12079404
Cellular Component	GO:0099634	postsynaptic specialization membrane	Chrna7	IDA		Rat	PMID:11588172\|RGD:13702268
Cellular Component	GO:0042734	presynaptic membrane	Chrna7	IEP		Mouse	PMID:24607281
Cellular Component	GO:0042734	presynaptic membrane	Chrna7	IDA		Mouse	PMID:24607281
Cellular Component	GO:0042734	presynaptic membrane	Chrna7	IDA		Rat	PMID:11588172\|RGD:13702268
Cellular Component	GO:0042734	presynaptic membrane	Chrna7	IDA		Rat	PMID:24607281\|RGD:13702281
Cellular Component	GO:0042734	presynaptic membrane	Chrna7	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0098897	spine apparatus membrane	Chrna7	IDA		Rat	PMID:11588172\|RGD:13702268
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Chrna7	IDA		Rat	PMID:21540349\|RGD:12790638
Biological Process	GO:0008306	associative learning	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:15922075
Biological Process	GO:0008306	associative learning	Chrna7	IGI	MGI:MGI:87891	Mouse	PMID:15541879
Biological Process	GO:0042113	B cell activation	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:16253349
Biological Process	GO:0042113	B cell activation	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:15963492
Biological Process	GO:0048149	behavioral response to ethanol	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:15489024
Biological Process	GO:0035095	behavioral response to nicotine	Chrna7	IGI	MGI:MGI:87891	Mouse	PMID:17470777
Biological Process	GO:0006816	calcium ion transport	CHRNA7	IMP		Human	PMID:10771023
Biological Process	GO:0006816	calcium ion transport	CHRNA7	IDA		Human	PMID:8145738
Biological Process	GO:0006816	calcium ion transport	Chrna7	IMP		Rat	PMID:15760934\|RGD:8554382
Biological Process	GO:0050890	cognition	CHRNA7	IMP		Human	PMID:16754836
Biological Process	GO:0140059	dendrite arborization	Chrna7	IMP		Mouse	MGI:MGI:5487905\|PMID:23270857
Biological Process	GO:0097061	dendritic spine organization	Chrna7	IMP		Mouse	MGI:MGI:5487905\|PMID:23270857
Biological Process	GO:0042416	dopamine biosynthetic process	Chrna7	IEP		Rat	PMID:12438507\|RGD:704388
Biological Process	GO:0006897	endocytosis	Chrna7	IMP		Mouse	PMID:16025111
Biological Process	GO:0051649	establishment of localization in cell	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:9364063
Biological Process	GO:0051649	establishment of localization in cell	Chrna7	IMP	MGI:MGI:2155604	Mouse	PMID:10800961
Biological Process	GO:0030317	flagellated sperm motility	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:15944242
Biological Process	GO:0060112	generation of ovulation cycle rhythm	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:15364017
Biological Process	GO:0032611	interleukin-1 beta production	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:12508119
Biological Process	GO:0032635	interleukin-6 production	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:12508119
Biological Process	GO:0006874	intracellular calcium ion homeostasis	CHRNA7	IMP		Human	PMID:16280133
Biological Process	GO:0007611	learning or memory	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4437154\|PMID:20164328
Biological Process	GO:0007611	learning or memory	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4352762\|PMID:19587288
Biological Process	GO:0007611	learning or memory	Chrna7	IGI	ComplexPortal:CPX-1134,UniProtKB:P05067:PRO_0000000092	Mouse	MGI:MGI:5825427\|PMID:19118188
Biological Process	GO:0007611	learning or memory	Chrna7	IMP		Rat	PMID:17055644\|RGD:151708697
Biological Process	GO:0051899	membrane depolarization	Chrna7	IDA		Mouse	MGI:MGI:6810690\|PMID:22039094
Biological Process	GO:0051899	membrane depolarization	Chrna7	IDA		Rat	PMID:19176801\|RGD:150521628
Biological Process	GO:0007613	memory	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:16923147
Biological Process	GO:0007613	memory	Chrna7	IDA		Rat	PMID:17898229\|RGD:12050111
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Chrna7	IGI	UniProtKB:P56818	Mouse	MGI:MGI:5819343\|PMID:20943921
Biological Process	GO:0098815	modulation of excitatory postsynaptic potential	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4889154\|PMID:20974225
Biological Process	GO:0098815	modulation of excitatory postsynaptic potential	Chrna7	IDA		Mouse	MGI:MGI:4889154\|PMID:20974225
Biological Process	GO:0034220	monoatomic ion transmembrane transport	CHRNA7	IDA		Human	PMID:21718690
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Chrna7	IDA		Rat	PMID:16282518\|RGD:1642691
Biological Process	GO:0006811	monoatomic ion transport	Chrna7	IMP	MGI:MGI:2155604	Mouse	PMID:10800961
Biological Process	GO:0006811	monoatomic ion transport	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:9364063
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	CHRNA7	IGI	UniProtKB:P05067	Human	PMID:20708605
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Chrna7	IMP		Rat	PMID:20505147\|RGD:8549538
Biological Process	GO:0050728	negative regulation of inflammatory response	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:16785311
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:12508119
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:12508119
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Chrna7	IDA		Mouse	MGI:MGI:3843740\|PMID:19230830
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	CHRNA7	IDA		Human	PMID:12508119
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	CHRNA7	IMP		Human	PMID:12508119
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:16785311
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:12508119
Biological Process	GO:0019228	neuronal action potential	Chrna7	IMP		Rat	PMID:15044058\|RGD:1600975
Biological Process	GO:0042698	ovulation cycle	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:1400473
Biological Process	GO:1902004	positive regulation of amyloid-beta formation	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4437154\|PMID:20164328
Biological Process	GO:0045766	positive regulation of angiogenesis	CHRNA7	IMP		Human	PMID:12189247
Biological Process	GO:0045766	positive regulation of angiogenesis	CHRNA7	IMP		Human	PMID:16280133
Biological Process	GO:0008284	positive regulation of cell population proliferation	CHRNA7	IMP		Human	PMID:16280133
Biological Process	GO:0008284	positive regulation of cell population proliferation	CHRNA7	IMP		Human	PMID:17498763
Biological Process	GO:1905920	positive regulation of CoA-transferase activity	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4437154\|PMID:20164328
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Chrna7	IDA		Mouse	MGI:MGI:5819349\|PMID:17898229
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4437154\|PMID:20164328
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Chrna7	IMP		Mouse	MGI:MGI:5825438\|PMID:11404397
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Chrna7	IMP		Rat	PMID:11404397\|RGD:12790656
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Chrna7	IDA		Rat	PMID:17898229\|RGD:12050111
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Chrna7	IGI	ComplexPortal:CPX-1134,UniProtKB:P05067:PRO_0000000092	Mouse	MGI:MGI:5825427\|PMID:19118188
Biological Process	GO:0010628	positive regulation of gene expression	Chrna7	IDA		Rat	PMID:17379406\|RGD:151708700
Biological Process	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:10942027
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Chrna7	IGI	ComplexPortal:CPX-1134,UniProtKB:P05067:PRO_0000000092	Mouse	MGI:MGI:5825427\|PMID:19118188
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4889154\|PMID:20974225
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Chrna7	IDA		Mouse	MGI:MGI:4889154\|PMID:20974225
Biological Process	GO:0043410	positive regulation of MAPK cascade	CHRNA7	IDA		Human	PMID:10771023
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	Chrna7	IMP		Mouse	MGI:MGI:3843740\|PMID:19230830
Biological Process	GO:0051247	positive regulation of protein metabolic process	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4437154\|PMID:20164328
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Chrna7	IDA		Mouse	MGI:MGI:5819349\|PMID:17898229
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Chrna7	EXP		Rat	PMID:21762741\|RGD:13702307
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Chrna7	IDA		Rat	PMID:21762741\|RGD:13702307
Biological Process	GO:1905906	regulation of amyloid fibril formation	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4437154\|PMID:20164328
Biological Process	GO:1902991	regulation of amyloid precursor protein catabolic process	CHRNA7	IGI	UniProtKB:P05067	Human	PMID:20708605
Biological Process	GO:0050727	regulation of inflammatory response	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:12508119
Biological Process	GO:0042391	regulation of membrane potential	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:9364063
Biological Process	GO:0042391	regulation of membrane potential	Chrna7	IMP	MGI:MGI:2155604	Mouse	PMID:10800961
Biological Process	GO:0042391	regulation of membrane potential	Chrna7	IDA		Rat	PMID:11222635\|RGD:8554133
Biological Process	GO:0042391	regulation of membrane potential	Chrna7	IMP		Rat	PMID:15760934\|RGD:8554382
Biological Process	GO:1901214	regulation of neuron death	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4437154\|PMID:20164328
Biological Process	GO:0014061	regulation of norepinephrine secretion	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:10942027
Biological Process	GO:2001023	regulation of response to drug	Chrna7	IDA		Rat	PMID:16282518\|RGD:1642691
Biological Process	GO:0032225	regulation of synaptic transmission, dopaminergic	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:16772172
Biological Process	GO:1905144	response to acetylcholine	CHRNA7	IDA		Human	PMID:17898229
Biological Process	GO:1905144	response to acetylcholine	Chrna7	IDA		Rat	PMID:16282518\|RGD:1642691
Biological Process	GO:1905144	response to acetylcholine	Chrna7	IDA		Rat	PMID:17898229\|RGD:12050111
Biological Process	GO:1905144	response to acetylcholine	Chrna7	IDA		Rat	PMID:21540349\|RGD:12790638
Biological Process	GO:1904645	response to amyloid-beta	Chrna7	IMP		Mouse	MGI:MGI:5825427\|PMID:19118188
Biological Process	GO:0046681	response to carbamate	Chrna7	IEP		Rat	PMID:15179037\|RGD:151676718
Biological Process	GO:0009409	response to cold	Chrna7	IDA		Mouse	MGI:MGI:3843740\|PMID:19230830
Biological Process	GO:0045471	response to ethanol	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:15555774
Biological Process	GO:0032094	response to food	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:15922075
Biological Process	GO:0001666	response to hypoxia	CHRNA7	IDA		Human	PMID:12189247
Biological Process	GO:0035094	response to nicotine	CHRNA7	IDA		Human	PMID:12189247
Biological Process	GO:0035094	response to nicotine	CHRNA7	IDA		Human	PMID:8145738
Biological Process	GO:0035094	response to nicotine	Chrna7	IGI	UniProtKB:P63085	Mouse	MGI:MGI:5825438\|PMID:11404397
Biological Process	GO:0035094	response to nicotine	Chrna7	IMP		Mouse	PMID:9495872
Biological Process	GO:0035094	response to nicotine	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:17291692
Biological Process	GO:0035094	response to nicotine	Chrna7	IGI	UniProtKB:P63086	Rat	PMID:11404397\|RGD:12790656
Biological Process	GO:0035094	response to nicotine	Chrna7	IDA		Rat	PMID:15801858\|RGD:1600992
Biological Process	GO:0035094	response to nicotine	chrna7a	IDA		Zfish	PMID:24862365
Biological Process	GO:0050893	sensory processing	Chrna7	IDA		Mouse	MGI:MGI:5819349\|PMID:17898229
Biological Process	GO:0050893	sensory processing	Chrna7	IDA		Rat	PMID:17898229\|RGD:12050111
Biological Process	GO:0007165	signal transduction	CHRNA7	IDA		Human	PMID:8906617
Biological Process	GO:0050808	synapse organization	Chrna7	IGI	UniProtKB:P05067	Mouse	MGI:MGI:4352762\|PMID:19587288
Biological Process	GO:0007271	synaptic transmission, cholinergic	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:9364063
Biological Process	GO:0007271	synaptic transmission, cholinergic	Chrna7	IMP		Rat	PMID:15044058\|RGD:1600975
Biological Process	GO:0042110	T cell activation	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:16253349
Biological Process	GO:0032640	tumor necrosis factor production	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:12508119
Biological Process	GO:0032640	tumor necrosis factor production	Chrna7	IMP	MGI:MGI:1888407	Mouse	PMID:16785311

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.