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Gene Ontology Browser
Term Detail
GO term:negative regulation of tumor necrosis factor production
Synonym: down regulation of tumor necrosis factor production
Synonym: down-regulation of tumor necrosis factor production
Synonym: downregulation of tumor necrosis factor production
Synonym: inhibition of tumor necrosis factor production
Synonym: negative regulation TNF-alpha production
Synonym: negative regulation TNF production
Synonym: negative regulation tumor necrosis factor-alpha production
GO id:GO:0032720
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
CommentsNote that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').
Number of paths to term: 21

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of multicellular organismal process
                                                is-anegative regulation of cytokine production
                                                        is-anegative regulation of chemokine production +
                                                        is-anegative regulation of connective tissue growth factor production
                                                        is-anegative regulation of cytokine production involved in immune response +
                                                        is-anegative regulation of cytokine production involved in inflammatory response
                                                        is-anegative regulation of fibroblast growth factor production
                                                        is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                        is-anegative regulation of hepatocyte growth factor production
                                                        is-anegative regulation of interferon-gamma production
                                                        is-anegative regulation of interleukin-1 production +
                                                        is-anegative regulation of interleukin-10 production
                                                        is-anegative regulation of interleukin-11 production
                                                        is-anegative regulation of interleukin-12 production
                                                        is-anegative regulation of interleukin-13 production
                                                        is-anegative regulation of interleukin-14 production
                                                        is-anegative regulation of interleukin-15 production
                                                        is-anegative regulation of interleukin-16 production
                                                        is-anegative regulation of interleukin-17 production
                                                        is-anegative regulation of interleukin-18 production
                                                        is-anegative regulation of interleukin-19 production
                                                        is-anegative regulation of interleukin-2 production
                                                        is-anegative regulation of interleukin-20 production
                                                        is-anegative regulation of interleukin-21 production
                                                        is-anegative regulation of interleukin-22 production
                                                        is-anegative regulation of interleukin-23 production
                                                        is-anegative regulation of interleukin-24 production
                                                        is-anegative regulation of interleukin-25 production
                                                        is-anegative regulation of interleukin-26 production
                                                        is-anegative regulation of interleukin-27 production
                                                        is-anegative regulation of interleukin-3 production
                                                        is-anegative regulation of interleukin-35 production
                                                        is-anegative regulation of interleukin-4 production
                                                        is-anegative regulation of interleukin-5 production
                                                        is-anegative regulation of interleukin-6 production
                                                        is-anegative regulation of interleukin-7 production
                                                        is-anegative regulation of interleukin-8 production
                                                        is-anegative regulation of interleukin-9 production
                                                        is-anegative regulation of lymphotoxin A production
                                                        is-anegative regulation of macrophage colony-stimulating factor production +
                                                        is-anegative regulation of TRAIL production
                                                        is-anegative regulation of transforming growth factor beta production +
                                                        is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        is-anegative regulation of type I interferon production +
                                                        is-anegative regulation of type III interferon production
                                                        is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of multicellular organismal process
                                        is-anegative regulation of multicellular organismal process
                                                is-anegative regulation of cytokine production
                                                        is-anegative regulation of chemokine production +
                                                        is-anegative regulation of connective tissue growth factor production
                                                        is-anegative regulation of cytokine production involved in immune response +
                                                        is-anegative regulation of cytokine production involved in inflammatory response
                                                        is-anegative regulation of fibroblast growth factor production
                                                        is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                        is-anegative regulation of hepatocyte growth factor production
                                                        is-anegative regulation of interferon-gamma production
                                                        is-anegative regulation of interleukin-1 production +
                                                        is-anegative regulation of interleukin-10 production
                                                        is-anegative regulation of interleukin-11 production
                                                        is-anegative regulation of interleukin-12 production
                                                        is-anegative regulation of interleukin-13 production
                                                        is-anegative regulation of interleukin-14 production
                                                        is-anegative regulation of interleukin-15 production
                                                        is-anegative regulation of interleukin-16 production
                                                        is-anegative regulation of interleukin-17 production
                                                        is-anegative regulation of interleukin-18 production
                                                        is-anegative regulation of interleukin-19 production
                                                        is-anegative regulation of interleukin-2 production
                                                        is-anegative regulation of interleukin-20 production
                                                        is-anegative regulation of interleukin-21 production
                                                        is-anegative regulation of interleukin-22 production
                                                        is-anegative regulation of interleukin-23 production
                                                        is-anegative regulation of interleukin-24 production
                                                        is-anegative regulation of interleukin-25 production
                                                        is-anegative regulation of interleukin-26 production
                                                        is-anegative regulation of interleukin-27 production
                                                        is-anegative regulation of interleukin-3 production
                                                        is-anegative regulation of interleukin-35 production
                                                        is-anegative regulation of interleukin-4 production
                                                        is-anegative regulation of interleukin-5 production
                                                        is-anegative regulation of interleukin-6 production
                                                        is-anegative regulation of interleukin-7 production
                                                        is-anegative regulation of interleukin-8 production
                                                        is-anegative regulation of interleukin-9 production
                                                        is-anegative regulation of lymphotoxin A production
                                                        is-anegative regulation of macrophage colony-stimulating factor production +
                                                        is-anegative regulation of TRAIL production
                                                        is-anegative regulation of transforming growth factor beta production +
                                                        is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        is-anegative regulation of type I interferon production +
                                                        is-anegative regulation of type III interferon production
                                                        is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of multicellular organismal process
                                        is-aregulation of cytokine production
                                                is-anegative regulation of cytokine production
                                                        is-anegative regulation of chemokine production +
                                                        is-anegative regulation of connective tissue growth factor production
                                                        is-anegative regulation of cytokine production involved in immune response +
                                                        is-anegative regulation of cytokine production involved in inflammatory response
                                                        is-anegative regulation of fibroblast growth factor production
                                                        is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                        is-anegative regulation of hepatocyte growth factor production
                                                        is-anegative regulation of interferon-gamma production
                                                        is-anegative regulation of interleukin-1 production +
                                                        is-anegative regulation of interleukin-10 production
                                                        is-anegative regulation of interleukin-11 production
                                                        is-anegative regulation of interleukin-12 production
                                                        is-anegative regulation of interleukin-13 production
                                                        is-anegative regulation of interleukin-14 production
                                                        is-anegative regulation of interleukin-15 production
                                                        is-anegative regulation of interleukin-16 production
                                                        is-anegative regulation of interleukin-17 production
                                                        is-anegative regulation of interleukin-18 production
                                                        is-anegative regulation of interleukin-19 production
                                                        is-anegative regulation of interleukin-2 production
                                                        is-anegative regulation of interleukin-20 production
                                                        is-anegative regulation of interleukin-21 production
                                                        is-anegative regulation of interleukin-22 production
                                                        is-anegative regulation of interleukin-23 production
                                                        is-anegative regulation of interleukin-24 production
                                                        is-anegative regulation of interleukin-25 production
                                                        is-anegative regulation of interleukin-26 production
                                                        is-anegative regulation of interleukin-27 production
                                                        is-anegative regulation of interleukin-3 production
                                                        is-anegative regulation of interleukin-35 production
                                                        is-anegative regulation of interleukin-4 production
                                                        is-anegative regulation of interleukin-5 production
                                                        is-anegative regulation of interleukin-6 production
                                                        is-anegative regulation of interleukin-7 production
                                                        is-anegative regulation of interleukin-8 production
                                                        is-anegative regulation of interleukin-9 production
                                                        is-anegative regulation of lymphotoxin A production
                                                        is-anegative regulation of macrophage colony-stimulating factor production +
                                                        is-anegative regulation of TRAIL production
                                                        is-anegative regulation of transforming growth factor beta production +
                                                        is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        is-anegative regulation of type I interferon production +
                                                        is-anegative regulation of type III interferon production
                                                        is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of multicellular organismal process
                                        is-aregulation of cytokine production
                                                is-aregulation of tumor necrosis factor production
                                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        is-apositive regulation of tumor necrosis factor production
                                                        is-aregulation of tumor necrosis factor biosynthetic process +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        negatively-regulatesnegative regulation of cytokine production
                                                is-anegative regulation of chemokine production +
                                                is-anegative regulation of connective tissue growth factor production
                                                is-anegative regulation of cytokine production involved in immune response +
                                                is-anegative regulation of cytokine production involved in inflammatory response
                                                is-anegative regulation of fibroblast growth factor production
                                                is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                is-anegative regulation of hepatocyte growth factor production
                                                is-anegative regulation of interferon-gamma production
                                                is-anegative regulation of interleukin-1 production +
                                                is-anegative regulation of interleukin-10 production
                                                is-anegative regulation of interleukin-11 production
                                                is-anegative regulation of interleukin-12 production
                                                is-anegative regulation of interleukin-13 production
                                                is-anegative regulation of interleukin-14 production
                                                is-anegative regulation of interleukin-15 production
                                                is-anegative regulation of interleukin-16 production
                                                is-anegative regulation of interleukin-17 production
                                                is-anegative regulation of interleukin-18 production
                                                is-anegative regulation of interleukin-19 production
                                                is-anegative regulation of interleukin-2 production
                                                is-anegative regulation of interleukin-20 production
                                                is-anegative regulation of interleukin-21 production
                                                is-anegative regulation of interleukin-22 production
                                                is-anegative regulation of interleukin-23 production
                                                is-anegative regulation of interleukin-24 production
                                                is-anegative regulation of interleukin-25 production
                                                is-anegative regulation of interleukin-26 production
                                                is-anegative regulation of interleukin-27 production
                                                is-anegative regulation of interleukin-3 production
                                                is-anegative regulation of interleukin-35 production
                                                is-anegative regulation of interleukin-4 production
                                                is-anegative regulation of interleukin-5 production
                                                is-anegative regulation of interleukin-6 production
                                                is-anegative regulation of interleukin-7 production
                                                is-anegative regulation of interleukin-8 production
                                                is-anegative regulation of interleukin-9 production
                                                is-anegative regulation of lymphotoxin A production
                                                is-anegative regulation of macrophage colony-stimulating factor production +
                                                is-anegative regulation of TRAIL production
                                                is-anegative regulation of transforming growth factor beta production +
                                                is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                is-anegative regulation of type I interferon production +
                                                is-anegative regulation of type III interferon production
                                                is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        regulatesregulation of cytokine production
                                                is-anegative regulation of cytokine production
                                                        is-anegative regulation of chemokine production +
                                                        is-anegative regulation of connective tissue growth factor production
                                                        is-anegative regulation of cytokine production involved in immune response +
                                                        is-anegative regulation of cytokine production involved in inflammatory response
                                                        is-anegative regulation of fibroblast growth factor production
                                                        is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                        is-anegative regulation of hepatocyte growth factor production
                                                        is-anegative regulation of interferon-gamma production
                                                        is-anegative regulation of interleukin-1 production +
                                                        is-anegative regulation of interleukin-10 production
                                                        is-anegative regulation of interleukin-11 production
                                                        is-anegative regulation of interleukin-12 production
                                                        is-anegative regulation of interleukin-13 production
                                                        is-anegative regulation of interleukin-14 production
                                                        is-anegative regulation of interleukin-15 production
                                                        is-anegative regulation of interleukin-16 production
                                                        is-anegative regulation of interleukin-17 production
                                                        is-anegative regulation of interleukin-18 production
                                                        is-anegative regulation of interleukin-19 production
                                                        is-anegative regulation of interleukin-2 production
                                                        is-anegative regulation of interleukin-20 production
                                                        is-anegative regulation of interleukin-21 production
                                                        is-anegative regulation of interleukin-22 production
                                                        is-anegative regulation of interleukin-23 production
                                                        is-anegative regulation of interleukin-24 production
                                                        is-anegative regulation of interleukin-25 production
                                                        is-anegative regulation of interleukin-26 production
                                                        is-anegative regulation of interleukin-27 production
                                                        is-anegative regulation of interleukin-3 production
                                                        is-anegative regulation of interleukin-35 production
                                                        is-anegative regulation of interleukin-4 production
                                                        is-anegative regulation of interleukin-5 production
                                                        is-anegative regulation of interleukin-6 production
                                                        is-anegative regulation of interleukin-7 production
                                                        is-anegative regulation of interleukin-8 production
                                                        is-anegative regulation of interleukin-9 production
                                                        is-anegative regulation of lymphotoxin A production
                                                        is-anegative regulation of macrophage colony-stimulating factor production +
                                                        is-anegative regulation of TRAIL production
                                                        is-anegative regulation of transforming growth factor beta production +
                                                        is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        is-anegative regulation of type I interferon production +
                                                        is-anegative regulation of type III interferon production
                                                        is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        regulatesregulation of cytokine production
                                                is-aregulation of tumor necrosis factor production
                                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        is-apositive regulation of tumor necrosis factor production
                                                        is-aregulation of tumor necrosis factor biosynthetic process +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        is-atumor necrosis factor superfamily cytokine production
                                                is-atumor necrosis factor production
                                                        negatively-regulatesnegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        positively-regulatespositive regulation of tumor necrosis factor production
                                                        regulatesregulation of tumor necrosis factor production +
                                                        part-oftumor necrosis factor biosynthetic process +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        is-atumor necrosis factor superfamily cytokine production
                                                is-atumor necrosis factor production
                                                        regulatesregulation of tumor necrosis factor production
                                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                                is-apositive regulation of tumor necrosis factor production
                                                                is-aregulation of tumor necrosis factor biosynthetic process +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                negatively-regulatesnegative regulation of multicellular organismal process
                                        is-anegative regulation of cytokine production
                                                is-anegative regulation of chemokine production +
                                                is-anegative regulation of connective tissue growth factor production
                                                is-anegative regulation of cytokine production involved in immune response +
                                                is-anegative regulation of cytokine production involved in inflammatory response
                                                is-anegative regulation of fibroblast growth factor production
                                                is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                is-anegative regulation of hepatocyte growth factor production
                                                is-anegative regulation of interferon-gamma production
                                                is-anegative regulation of interleukin-1 production +
                                                is-anegative regulation of interleukin-10 production
                                                is-anegative regulation of interleukin-11 production
                                                is-anegative regulation of interleukin-12 production
                                                is-anegative regulation of interleukin-13 production
                                                is-anegative regulation of interleukin-14 production
                                                is-anegative regulation of interleukin-15 production
                                                is-anegative regulation of interleukin-16 production
                                                is-anegative regulation of interleukin-17 production
                                                is-anegative regulation of interleukin-18 production
                                                is-anegative regulation of interleukin-19 production
                                                is-anegative regulation of interleukin-2 production
                                                is-anegative regulation of interleukin-20 production
                                                is-anegative regulation of interleukin-21 production
                                                is-anegative regulation of interleukin-22 production
                                                is-anegative regulation of interleukin-23 production
                                                is-anegative regulation of interleukin-24 production
                                                is-anegative regulation of interleukin-25 production
                                                is-anegative regulation of interleukin-26 production
                                                is-anegative regulation of interleukin-27 production
                                                is-anegative regulation of interleukin-3 production
                                                is-anegative regulation of interleukin-35 production
                                                is-anegative regulation of interleukin-4 production
                                                is-anegative regulation of interleukin-5 production
                                                is-anegative regulation of interleukin-6 production
                                                is-anegative regulation of interleukin-7 production
                                                is-anegative regulation of interleukin-8 production
                                                is-anegative regulation of interleukin-9 production
                                                is-anegative regulation of lymphotoxin A production
                                                is-anegative regulation of macrophage colony-stimulating factor production +
                                                is-anegative regulation of TRAIL production
                                                is-anegative regulation of transforming growth factor beta production +
                                                is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                is-anegative regulation of type I interferon production +
                                                is-anegative regulation of type III interferon production
                                                is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                negatively-regulatesnegative regulation of biological process
                        is-anegative regulation of multicellular organismal process
                                is-anegative regulation of cytokine production
                                        is-anegative regulation of chemokine production +
                                        is-anegative regulation of connective tissue growth factor production
                                        is-anegative regulation of cytokine production involved in immune response +
                                        is-anegative regulation of cytokine production involved in inflammatory response
                                        is-anegative regulation of fibroblast growth factor production
                                        is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                        is-anegative regulation of hepatocyte growth factor production
                                        is-anegative regulation of interferon-gamma production
                                        is-anegative regulation of interleukin-1 production +
                                        is-anegative regulation of interleukin-10 production
                                        is-anegative regulation of interleukin-11 production
                                        is-anegative regulation of interleukin-12 production
                                        is-anegative regulation of interleukin-13 production
                                        is-anegative regulation of interleukin-14 production
                                        is-anegative regulation of interleukin-15 production
                                        is-anegative regulation of interleukin-16 production
                                        is-anegative regulation of interleukin-17 production
                                        is-anegative regulation of interleukin-18 production
                                        is-anegative regulation of interleukin-19 production
                                        is-anegative regulation of interleukin-2 production
                                        is-anegative regulation of interleukin-20 production
                                        is-anegative regulation of interleukin-21 production
                                        is-anegative regulation of interleukin-22 production
                                        is-anegative regulation of interleukin-23 production
                                        is-anegative regulation of interleukin-24 production
                                        is-anegative regulation of interleukin-25 production
                                        is-anegative regulation of interleukin-26 production
                                        is-anegative regulation of interleukin-27 production
                                        is-anegative regulation of interleukin-3 production
                                        is-anegative regulation of interleukin-35 production
                                        is-anegative regulation of interleukin-4 production
                                        is-anegative regulation of interleukin-5 production
                                        is-anegative regulation of interleukin-6 production
                                        is-anegative regulation of interleukin-7 production
                                        is-anegative regulation of interleukin-8 production
                                        is-anegative regulation of interleukin-9 production
                                        is-anegative regulation of lymphotoxin A production
                                        is-anegative regulation of macrophage colony-stimulating factor production +
                                        is-anegative regulation of TRAIL production
                                        is-anegative regulation of transforming growth factor beta production +
                                        is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                        is-anegative regulation of type I interferon production +
                                        is-anegative regulation of type III interferon production
                                        is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-anegative regulation of biological process
                                is-anegative regulation of multicellular organismal process
                                        is-anegative regulation of cytokine production
                                                is-anegative regulation of chemokine production +
                                                is-anegative regulation of connective tissue growth factor production
                                                is-anegative regulation of cytokine production involved in immune response +
                                                is-anegative regulation of cytokine production involved in inflammatory response
                                                is-anegative regulation of fibroblast growth factor production
                                                is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                is-anegative regulation of hepatocyte growth factor production
                                                is-anegative regulation of interferon-gamma production
                                                is-anegative regulation of interleukin-1 production +
                                                is-anegative regulation of interleukin-10 production
                                                is-anegative regulation of interleukin-11 production
                                                is-anegative regulation of interleukin-12 production
                                                is-anegative regulation of interleukin-13 production
                                                is-anegative regulation of interleukin-14 production
                                                is-anegative regulation of interleukin-15 production
                                                is-anegative regulation of interleukin-16 production
                                                is-anegative regulation of interleukin-17 production
                                                is-anegative regulation of interleukin-18 production
                                                is-anegative regulation of interleukin-19 production
                                                is-anegative regulation of interleukin-2 production
                                                is-anegative regulation of interleukin-20 production
                                                is-anegative regulation of interleukin-21 production
                                                is-anegative regulation of interleukin-22 production
                                                is-anegative regulation of interleukin-23 production
                                                is-anegative regulation of interleukin-24 production
                                                is-anegative regulation of interleukin-25 production
                                                is-anegative regulation of interleukin-26 production
                                                is-anegative regulation of interleukin-27 production
                                                is-anegative regulation of interleukin-3 production
                                                is-anegative regulation of interleukin-35 production
                                                is-anegative regulation of interleukin-4 production
                                                is-anegative regulation of interleukin-5 production
                                                is-anegative regulation of interleukin-6 production
                                                is-anegative regulation of interleukin-7 production
                                                is-anegative regulation of interleukin-8 production
                                                is-anegative regulation of interleukin-9 production
                                                is-anegative regulation of lymphotoxin A production
                                                is-anegative regulation of macrophage colony-stimulating factor production +
                                                is-anegative regulation of TRAIL production
                                                is-anegative regulation of transforming growth factor beta production +
                                                is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                is-anegative regulation of type I interferon production +
                                                is-anegative regulation of type III interferon production
                                                is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of multicellular organismal process
                                is-anegative regulation of multicellular organismal process
                                        is-anegative regulation of cytokine production
                                                is-anegative regulation of chemokine production +
                                                is-anegative regulation of connective tissue growth factor production
                                                is-anegative regulation of cytokine production involved in immune response +
                                                is-anegative regulation of cytokine production involved in inflammatory response
                                                is-anegative regulation of fibroblast growth factor production
                                                is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                is-anegative regulation of hepatocyte growth factor production
                                                is-anegative regulation of interferon-gamma production
                                                is-anegative regulation of interleukin-1 production +
                                                is-anegative regulation of interleukin-10 production
                                                is-anegative regulation of interleukin-11 production
                                                is-anegative regulation of interleukin-12 production
                                                is-anegative regulation of interleukin-13 production
                                                is-anegative regulation of interleukin-14 production
                                                is-anegative regulation of interleukin-15 production
                                                is-anegative regulation of interleukin-16 production
                                                is-anegative regulation of interleukin-17 production
                                                is-anegative regulation of interleukin-18 production
                                                is-anegative regulation of interleukin-19 production
                                                is-anegative regulation of interleukin-2 production
                                                is-anegative regulation of interleukin-20 production
                                                is-anegative regulation of interleukin-21 production
                                                is-anegative regulation of interleukin-22 production
                                                is-anegative regulation of interleukin-23 production
                                                is-anegative regulation of interleukin-24 production
                                                is-anegative regulation of interleukin-25 production
                                                is-anegative regulation of interleukin-26 production
                                                is-anegative regulation of interleukin-27 production
                                                is-anegative regulation of interleukin-3 production
                                                is-anegative regulation of interleukin-35 production
                                                is-anegative regulation of interleukin-4 production
                                                is-anegative regulation of interleukin-5 production
                                                is-anegative regulation of interleukin-6 production
                                                is-anegative regulation of interleukin-7 production
                                                is-anegative regulation of interleukin-8 production
                                                is-anegative regulation of interleukin-9 production
                                                is-anegative regulation of lymphotoxin A production
                                                is-anegative regulation of macrophage colony-stimulating factor production +
                                                is-anegative regulation of TRAIL production
                                                is-anegative regulation of transforming growth factor beta production +
                                                is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                is-anegative regulation of type I interferon production +
                                                is-anegative regulation of type III interferon production
                                                is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of multicellular organismal process
                                is-aregulation of cytokine production
                                        is-anegative regulation of cytokine production
                                                is-anegative regulation of chemokine production +
                                                is-anegative regulation of connective tissue growth factor production
                                                is-anegative regulation of cytokine production involved in immune response +
                                                is-anegative regulation of cytokine production involved in inflammatory response
                                                is-anegative regulation of fibroblast growth factor production
                                                is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                is-anegative regulation of hepatocyte growth factor production
                                                is-anegative regulation of interferon-gamma production
                                                is-anegative regulation of interleukin-1 production +
                                                is-anegative regulation of interleukin-10 production
                                                is-anegative regulation of interleukin-11 production
                                                is-anegative regulation of interleukin-12 production
                                                is-anegative regulation of interleukin-13 production
                                                is-anegative regulation of interleukin-14 production
                                                is-anegative regulation of interleukin-15 production
                                                is-anegative regulation of interleukin-16 production
                                                is-anegative regulation of interleukin-17 production
                                                is-anegative regulation of interleukin-18 production
                                                is-anegative regulation of interleukin-19 production
                                                is-anegative regulation of interleukin-2 production
                                                is-anegative regulation of interleukin-20 production
                                                is-anegative regulation of interleukin-21 production
                                                is-anegative regulation of interleukin-22 production
                                                is-anegative regulation of interleukin-23 production
                                                is-anegative regulation of interleukin-24 production
                                                is-anegative regulation of interleukin-25 production
                                                is-anegative regulation of interleukin-26 production
                                                is-anegative regulation of interleukin-27 production
                                                is-anegative regulation of interleukin-3 production
                                                is-anegative regulation of interleukin-35 production
                                                is-anegative regulation of interleukin-4 production
                                                is-anegative regulation of interleukin-5 production
                                                is-anegative regulation of interleukin-6 production
                                                is-anegative regulation of interleukin-7 production
                                                is-anegative regulation of interleukin-8 production
                                                is-anegative regulation of interleukin-9 production
                                                is-anegative regulation of lymphotoxin A production
                                                is-anegative regulation of macrophage colony-stimulating factor production +
                                                is-anegative regulation of TRAIL production
                                                is-anegative regulation of transforming growth factor beta production +
                                                is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                is-anegative regulation of type I interferon production +
                                                is-anegative regulation of type III interferon production
                                                is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of multicellular organismal process
                                is-aregulation of cytokine production
                                        is-aregulation of tumor necrosis factor production
                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                is-apositive regulation of tumor necrosis factor production
                                                is-aregulation of tumor necrosis factor biosynthetic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        negatively-regulatesnegative regulation of cytokine production
                                                is-anegative regulation of chemokine production +
                                                is-anegative regulation of connective tissue growth factor production
                                                is-anegative regulation of cytokine production involved in immune response +
                                                is-anegative regulation of cytokine production involved in inflammatory response
                                                is-anegative regulation of fibroblast growth factor production
                                                is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                is-anegative regulation of hepatocyte growth factor production
                                                is-anegative regulation of interferon-gamma production
                                                is-anegative regulation of interleukin-1 production +
                                                is-anegative regulation of interleukin-10 production
                                                is-anegative regulation of interleukin-11 production
                                                is-anegative regulation of interleukin-12 production
                                                is-anegative regulation of interleukin-13 production
                                                is-anegative regulation of interleukin-14 production
                                                is-anegative regulation of interleukin-15 production
                                                is-anegative regulation of interleukin-16 production
                                                is-anegative regulation of interleukin-17 production
                                                is-anegative regulation of interleukin-18 production
                                                is-anegative regulation of interleukin-19 production
                                                is-anegative regulation of interleukin-2 production
                                                is-anegative regulation of interleukin-20 production
                                                is-anegative regulation of interleukin-21 production
                                                is-anegative regulation of interleukin-22 production
                                                is-anegative regulation of interleukin-23 production
                                                is-anegative regulation of interleukin-24 production
                                                is-anegative regulation of interleukin-25 production
                                                is-anegative regulation of interleukin-26 production
                                                is-anegative regulation of interleukin-27 production
                                                is-anegative regulation of interleukin-3 production
                                                is-anegative regulation of interleukin-35 production
                                                is-anegative regulation of interleukin-4 production
                                                is-anegative regulation of interleukin-5 production
                                                is-anegative regulation of interleukin-6 production
                                                is-anegative regulation of interleukin-7 production
                                                is-anegative regulation of interleukin-8 production
                                                is-anegative regulation of interleukin-9 production
                                                is-anegative regulation of lymphotoxin A production
                                                is-anegative regulation of macrophage colony-stimulating factor production +
                                                is-anegative regulation of TRAIL production
                                                is-anegative regulation of transforming growth factor beta production +
                                                is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                is-anegative regulation of type I interferon production +
                                                is-anegative regulation of type III interferon production
                                                is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        regulatesregulation of cytokine production
                                                is-anegative regulation of cytokine production
                                                        is-anegative regulation of chemokine production +
                                                        is-anegative regulation of connective tissue growth factor production
                                                        is-anegative regulation of cytokine production involved in immune response +
                                                        is-anegative regulation of cytokine production involved in inflammatory response
                                                        is-anegative regulation of fibroblast growth factor production
                                                        is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                        is-anegative regulation of hepatocyte growth factor production
                                                        is-anegative regulation of interferon-gamma production
                                                        is-anegative regulation of interleukin-1 production +
                                                        is-anegative regulation of interleukin-10 production
                                                        is-anegative regulation of interleukin-11 production
                                                        is-anegative regulation of interleukin-12 production
                                                        is-anegative regulation of interleukin-13 production
                                                        is-anegative regulation of interleukin-14 production
                                                        is-anegative regulation of interleukin-15 production
                                                        is-anegative regulation of interleukin-16 production
                                                        is-anegative regulation of interleukin-17 production
                                                        is-anegative regulation of interleukin-18 production
                                                        is-anegative regulation of interleukin-19 production
                                                        is-anegative regulation of interleukin-2 production
                                                        is-anegative regulation of interleukin-20 production
                                                        is-anegative regulation of interleukin-21 production
                                                        is-anegative regulation of interleukin-22 production
                                                        is-anegative regulation of interleukin-23 production
                                                        is-anegative regulation of interleukin-24 production
                                                        is-anegative regulation of interleukin-25 production
                                                        is-anegative regulation of interleukin-26 production
                                                        is-anegative regulation of interleukin-27 production
                                                        is-anegative regulation of interleukin-3 production
                                                        is-anegative regulation of interleukin-35 production
                                                        is-anegative regulation of interleukin-4 production
                                                        is-anegative regulation of interleukin-5 production
                                                        is-anegative regulation of interleukin-6 production
                                                        is-anegative regulation of interleukin-7 production
                                                        is-anegative regulation of interleukin-8 production
                                                        is-anegative regulation of interleukin-9 production
                                                        is-anegative regulation of lymphotoxin A production
                                                        is-anegative regulation of macrophage colony-stimulating factor production +
                                                        is-anegative regulation of TRAIL production
                                                        is-anegative regulation of transforming growth factor beta production +
                                                        is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        is-anegative regulation of type I interferon production +
                                                        is-anegative regulation of type III interferon production
                                                        is-asuppression by virus of host cytokine production +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        regulatesregulation of cytokine production
                                                is-aregulation of tumor necrosis factor production
                                                        is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        is-apositive regulation of tumor necrosis factor production
                                                        is-aregulation of tumor necrosis factor biosynthetic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        is-atumor necrosis factor superfamily cytokine production
                                                is-atumor necrosis factor production
                                                        negatively-regulatesnegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                        positively-regulatespositive regulation of tumor necrosis factor production
                                                        regulatesregulation of tumor necrosis factor production +
                                                        part-oftumor necrosis factor biosynthetic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-acytokine production
                                        is-atumor necrosis factor superfamily cytokine production
                                                is-atumor necrosis factor production
                                                        regulatesregulation of tumor necrosis factor production
                                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                                is-apositive regulation of tumor necrosis factor production
                                                                is-aregulation of tumor necrosis factor biosynthetic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                negatively-regulatesnegative regulation of multicellular organismal process
                                        is-anegative regulation of cytokine production
                                                is-anegative regulation of chemokine production +
                                                is-anegative regulation of connective tissue growth factor production
                                                is-anegative regulation of cytokine production involved in immune response +
                                                is-anegative regulation of cytokine production involved in inflammatory response
                                                is-anegative regulation of fibroblast growth factor production
                                                is-anegative regulation of granulocyte macrophage colony-stimulating factor production
                                                is-anegative regulation of hepatocyte growth factor production
                                                is-anegative regulation of interferon-gamma production
                                                is-anegative regulation of interleukin-1 production +
                                                is-anegative regulation of interleukin-10 production
                                                is-anegative regulation of interleukin-11 production
                                                is-anegative regulation of interleukin-12 production
                                                is-anegative regulation of interleukin-13 production
                                                is-anegative regulation of interleukin-14 production
                                                is-anegative regulation of interleukin-15 production
                                                is-anegative regulation of interleukin-16 production
                                                is-anegative regulation of interleukin-17 production
                                                is-anegative regulation of interleukin-18 production
                                                is-anegative regulation of interleukin-19 production
                                                is-anegative regulation of interleukin-2 production
                                                is-anegative regulation of interleukin-20 production
                                                is-anegative regulation of interleukin-21 production
                                                is-anegative regulation of interleukin-22 production
                                                is-anegative regulation of interleukin-23 production
                                                is-anegative regulation of interleukin-24 production
                                                is-anegative regulation of interleukin-25 production
                                                is-anegative regulation of interleukin-26 production
                                                is-anegative regulation of interleukin-27 production
                                                is-anegative regulation of interleukin-3 production
                                                is-anegative regulation of interleukin-35 production
                                                is-anegative regulation of interleukin-4 production
                                                is-anegative regulation of interleukin-5 production
                                                is-anegative regulation of interleukin-6 production
                                                is-anegative regulation of interleukin-7 production
                                                is-anegative regulation of interleukin-8 production
                                                is-anegative regulation of interleukin-9 production
                                                is-anegative regulation of lymphotoxin A production
                                                is-anegative regulation of macrophage colony-stimulating factor production +
                                                is-anegative regulation of TRAIL production
                                                is-anegative regulation of transforming growth factor beta production +
                                                is-anegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
                                                is-anegative regulation of tumor necrosis factor production [GO:0032720] (32 genes, 36 annotations)
                                                is-anegative regulation of type I interferon production +
                                                is-anegative regulation of type III interferon production
                                                is-asuppression by virus of host cytokine production +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory