About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:membrane depolarization
GO id:GO:0051899
Definition:The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane potential
                                        is-aaction potential +
                                        is-amembrane depolarization [GO:0051899] (93 genes, 138 annotations)
                                                is-amembrane depolarization during action potential +
                                                is-amitochondrial depolarization +
                                                negatively-regulatesnegative regulation of membrane depolarization +
                                                positively-regulatespositive regulation of membrane depolarization +
                                                regulatesregulation of membrane depolarization +
                                                is-aregulation of vascular smooth muscle cell membrane depolarization +
                                        is-amembrane hyperpolarization +
                                        is-amembrane repolarization +
                                        is-amodulation of excitatory postsynaptic potential +
                                        is-amodulation of inhibitory postsynaptic potential +
                                        is-anegative regulation of membrane potential +
                                        is-apositive regulation of membrane potential +
                                        is-aregulation of action potential +
                                        is-aregulation of cardiac muscle cell membrane potential
                                        is-aregulation of membrane depolarization +
                                        is-aregulation of membrane hyperpolarization +
                                        is-aregulation of membrane potential in photoreceptor cell +
                                        is-aregulation of membrane repolarization +
                                        is-aregulation of mitochondrial membrane potential +
                                        is-aregulation of postsynaptic membrane potential +
                                        is-aregulation of presynaptic membrane potential
                                        is-aregulation of resting membrane potential
                                        is-aregulation of voltage-gated sodium channel activity +
                                        is-aspike train +
                                        is-astabilization of membrane potential

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.08
The Jackson Laboratory