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Gene Ontology Browser
Term Detail
GO term:membrane depolarization
GO id:GO:0051899
Definition:The process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-acellular homeostasis
                                                is-acellular chemical homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-amembrane depolarization [GO:0051899] (84 genes, 125 annotations)
                                                                                is-amembrane depolarization involved in regulation of action potential +
                                                                                is-amitochondrial depolarization +
                                                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                                                regulatesregulation of membrane depolarization +
                                                                        is-amembrane hyperpolarization +
                                                                        is-amembrane repolarization +
                                                                        is-anegative regulation of membrane potential +
                                                                        is-apositive regulation of membrane potential +
                                                                        is-aregulation of action potential +
                                                                        is-aregulation of cardiac muscle cell membrane potential +
                                                                        is-aregulation of membrane potential in photoreceptor cell +
                                                                        is-aregulation of membrane repolarization +
                                                                        is-aregulation of mitochondrial membrane potential +
                                                                        is-aregulation of postsynaptic membrane potential +
                                                                        is-aregulation of resting membrane potential
                                                                        is-astabilization of membrane potential


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-achemical homeostasis
                                                is-acellular chemical homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-amembrane depolarization [GO:0051899] (84 genes, 125 annotations)
                                                                                is-amembrane depolarization involved in regulation of action potential +
                                                                                is-amitochondrial depolarization +
                                                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                                                regulatesregulation of membrane depolarization +
                                                                        is-amembrane hyperpolarization +
                                                                        is-amembrane repolarization +
                                                                        is-anegative regulation of membrane potential +
                                                                        is-apositive regulation of membrane potential +
                                                                        is-aregulation of action potential +
                                                                        is-aregulation of cardiac muscle cell membrane potential +
                                                                        is-aregulation of membrane potential in photoreceptor cell +
                                                                        is-aregulation of membrane repolarization +
                                                                        is-aregulation of mitochondrial membrane potential +
                                                                        is-aregulation of postsynaptic membrane potential +
                                                                        is-aregulation of resting membrane potential
                                                                        is-astabilization of membrane potential


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-ahomeostatic process
                                        is-achemical homeostasis
                                                is-aion homeostasis
                                                        is-acellular ion homeostasis
                                                                is-aregulation of membrane potential
                                                                        is-amembrane depolarization [GO:0051899] (84 genes, 125 annotations)
                                                                                is-amembrane depolarization involved in regulation of action potential +
                                                                                is-amitochondrial depolarization +
                                                                                is-aregulation of excitatory postsynaptic membrane potential +
                                                                                regulatesregulation of membrane depolarization +
                                                                        is-amembrane hyperpolarization +
                                                                        is-amembrane repolarization +
                                                                        is-anegative regulation of membrane potential +
                                                                        is-apositive regulation of membrane potential +
                                                                        is-aregulation of action potential +
                                                                        is-aregulation of cardiac muscle cell membrane potential +
                                                                        is-aregulation of membrane potential in photoreceptor cell +
                                                                        is-aregulation of membrane repolarization +
                                                                        is-aregulation of mitochondrial membrane potential +
                                                                        is-aregulation of postsynaptic membrane potential +
                                                                        is-aregulation of resting membrane potential
                                                                        is-astabilization of membrane potential


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular homeostasis
                                        is-acellular chemical homeostasis
                                                is-acellular ion homeostasis
                                                        is-aregulation of membrane potential
                                                                is-amembrane depolarization [GO:0051899] (84 genes, 125 annotations)
                                                                        is-amembrane depolarization involved in regulation of action potential +
                                                                        is-amitochondrial depolarization +
                                                                        is-aregulation of excitatory postsynaptic membrane potential +
                                                                        regulatesregulation of membrane depolarization +
                                                                is-amembrane hyperpolarization +
                                                                is-amembrane repolarization +
                                                                is-anegative regulation of membrane potential +
                                                                is-apositive regulation of membrane potential +
                                                                is-aregulation of action potential +
                                                                is-aregulation of cardiac muscle cell membrane potential +
                                                                is-aregulation of membrane potential in photoreceptor cell +
                                                                is-aregulation of membrane repolarization +
                                                                is-aregulation of mitochondrial membrane potential +
                                                                is-aregulation of postsynaptic membrane potential +
                                                                is-aregulation of resting membrane potential
                                                                is-astabilization of membrane potential


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular homeostasis
                                        is-acellular chemical homeostasis
                                                is-acellular ion homeostasis
                                                        is-aregulation of membrane potential
                                                                is-amembrane depolarization [GO:0051899] (84 genes, 125 annotations)
                                                                        is-amembrane depolarization involved in regulation of action potential +
                                                                        is-amitochondrial depolarization +
                                                                        is-aregulation of excitatory postsynaptic membrane potential +
                                                                        regulatesregulation of membrane depolarization +
                                                                is-amembrane hyperpolarization +
                                                                is-amembrane repolarization +
                                                                is-anegative regulation of membrane potential +
                                                                is-apositive regulation of membrane potential +
                                                                is-aregulation of action potential +
                                                                is-aregulation of cardiac muscle cell membrane potential +
                                                                is-aregulation of membrane potential in photoreceptor cell +
                                                                is-aregulation of membrane repolarization +
                                                                is-aregulation of mitochondrial membrane potential +
                                                                is-aregulation of postsynaptic membrane potential +
                                                                is-aregulation of resting membrane potential
                                                                is-astabilization of membrane potential


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/22/2013
MGI 5.13
The Jackson Laboratory