Excel File Text File All mouse models of bone remodeling disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      autosomal dominant hypophosphatemic rickets Fgf23tm1.1Kew/Fgf23tm1.1Kew B6.129-Fgf23tm1.1Kew J:180061 View
autosomal dominant hypophosphatemic rickets Fgf23tm1Blan/Fgf23tm1Blan
PhexHyp/Y
Not Specified J:94041 View
autosomal dominant osteopetrosis 2 Clcn7tm1.1Aros/Clcn7tm1.1Aros involves: 129P2/OlaHsd * C57BL/6N J:273179 View
autosomal dominant osteopetrosis 2 Clcn7tm1.1Mawa/Clcn7+ involves: C57BL/6J * C57BL/6N * CD-1 J:254787 View
autosomal dominant osteopetrosis 2 Clcn7tm1.1Mjec/Clcn7+ involves: 129 * 129S/SvEv * C57BL/6 J:203761 View
autosomal dominant osteopetrosis 2 Clcn7tm1.1Mjec/Clcn7+ involves: 129S/SvEv * C57BL/6 * DBA/2J J:203761 View
autosomal dominant osteopetrosis 2 Clcn7tm1.1Teti/Clcn7+ involves: 129S2/SvPas * C57BL/6 J:203761 View
autosomal dominant osteopetrosis 2 Clcn7tm1.1Teti/Clcn7tm1.1Teti involves: 129S2/SvPas * C57BL/6 J:203761 View
autosomal dominant osteopetrosis 2 Clcn7tm1.1Teti/Clcn7tm1.1Teti involves: 129S2/SvPas * CD-1 J:203761 View
autosomal recessive osteopetrosis 1 Tcirg1oc/Tcirg1oc B6C3Fe a/a-Tcirg1oc/J J:61295 View
autosomal recessive osteopetrosis 1 Tcirg1tm1Ypl/Tcirg1tm1Ypl involves: 129S4/SvJae * C57BL/6J J:58795 View
autosomal recessive osteopetrosis 2 Tnfsf11gum/Tnfsf11gum STOCK Tnfsf11gum/GrsrJ J:223062 View
autosomal recessive osteopetrosis 2 Tnfsf11tles/Tnfsf11tles involves: 129S6/SvEvTac * C57BL/6J J:179743 View
autosomal recessive osteopetrosis 2 Tnfsf11tm1Ywc/Tnfsf11tm1Ywc involves: 129P2/OlaHsd J:233265 View
autosomal recessive osteopetrosis 3 Car2n/Car2n involves: C57BL/6J * DBA/2J J:19268 View
autosomal recessive osteopetrosis 4 Clcn7tm1Tjj/Clcn7tm1Tjj involves: 129P2/OlaHsd * C57BL/6 J:67273 View
autosomal recessive osteopetrosis 4 Clcn7tm2Tjj/Clcn7tm2Tjj involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:67273 View
autosomal recessive osteopetrosis 5 Ostm1gl/Ostm1gl GL/Le Edardl-J +/+ Ostm1gl/J J:5561 View
autosomal recessive osteopetrosis 6 Ctsktm1(cre)Ska/Ctsk+
Plekhm1tm1.1Hzhao/Plekhm1tm1.1Hzhao
involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj J:236517 View
autosomal recessive osteopetrosis 6 Plekhm1tm1.2Hzhao/Plekhm1tm1.2Hzhao involves: 129S1/Sv * C57BL/6J J:236517 View
autosomal recessive osteopetrosis 8 Snx10em1Ael/Snx10em1Ael involves: 129 * C57BL/6J * C57BL/6JOlaHsd J:289051 View
autosomal recessive osteopetrosis 8 Snx10em2Ael/Snx10em2Ael involves: 129 * C57BL/6J * C57BL/6JOlaHsd J:289051 View
craniotubular dysplasia Ikegawa type Tmem53em1Ikeg/Tmem53em1Ikeg Not Specified J:306057 View
hereditary hypophosphatemic rickets with hypercalciuria Slc34a1tm1Hten/Slc34a1tm1Hten involves: 129S2/SvPas * C57BL/6J J:47637 View
hereditary hypophosphatemic rickets with hypercalciuria Slc34a1tm1Hten/Slc34a1tm1Hten
Slc34a3tm1Kimi/Slc34a3tm1Kimi
B6.129-Slc34a3tm1Kimi Slc34a1tm1Hten J:152195 View
hereditary multiple exostoses Ext1tm1.1Vcs/Ext1tm1.1Vcs
Tg(Col2a1-cre/ERT)KA3Smac/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N J:242977 View
hereditary multiple exostoses Ext1tm1.1Vcs/Ext1tm1.1Vcs
Tg(Col2a1-rtTA,tetO-cre)22Pjro/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL J:157599 View
hereditary multiple exostoses Ext1tm1Vcs/Ext1tm1Vcs
Tg(Col2a1-rtTA,tetO-cre)22Pjro/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:157599 View
hereditary multiple exostoses Ext1tm1Yama/Ext1tm1Yama
Acantm1(cre/ERT2)Crm/Acan+
involves: 129S5/SvEvBrd * 129S6/SvEvTac * C57BL/6NCrl J:242977 View
hereditary multiple exostoses Ext1tm1Yama/Ext1tm1Yama
Tg(Col2a1-cre/ERT)KA3Smac/0
involves: 129S5/SvEvBrd * FVB/N J:161395 View
osteopathia striata with cranial sclerosis Amer1tm1.1Nbar/Y
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJae * C57BL/6 * SJL J:173242 View
osteopathia striata with cranial sclerosis Amer1tm1.2Nbar/Y involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL J:173242 View
osteoporosis Tg(APCS-Tnfsf11*)#aKhs/0 C57BL/6J-Tg(APCS-Tnfsf11*)#aKhs J:264357 View
Paget's disease of bone Sqstm1tm1.1Sral/Sqstm1+ involves: 129/Sv * 129P2/OlaHsd * C57BL/6 J:173755 View
Paget's disease of bone Sqstm1tm1.1Sral/Sqstm1tm1.1Sral involves: 129/Sv * 129P2/OlaHsd * C57BL/6 J:173755 View
Paget's disease of bone Sqstm1tm1Keta/Sqstm1tm1Keta involves: 129 * C57BL/6N J:264183 View
Paget's disease of bone Tnfrsf11atm1.1Sral/Tnfrsf11a+ B6.129P2(Cg)-Tnfrsf11atm1.1Sral J:312215 View
rickets Cyp27b1tm1Dgo/Cyp27b1tm1Dgo involves: 129S1/Sv * 129X1/SvJ * BALB/c J:70030 View
rickets Cyp27b1tm1Star/Cyp27b1tm1Star involves: 129S1/Sv * 129X1/SvJ J:71928, J:71937, J:78635, J:90983, J:90984 View
rickets Tg(VDR*L233S,luc)T807Pike/0
Vdrtm1Mbd/Vdrtm1Mbd
involves: 129S4/SvJae * C57BL/6 J:218709 View
rickets Vdrtm1Mbd/Vdrtm1Mbd involves: 129S4/SvJae J:42815 View
rickets Vdrtm1Mbd/Vdrtm1Mbd involves: 129S4/SvJae * C57BL/6J J:99866 View
rickets Vdrtm1Ska/Vdrtm1Ska involves: C57BL/6NCrlj * CBA/JNCrlj J:42054, J:83237 View
sclerosteosis 1 Sosttm1Paz/Sosttm1Paz involves: 129/Sv * Black Swiss J:213541 View
sclerosteosis 2 Lrp4mdig-3J/Lrp4mdig-3J B6.Cg-Lrp4mdig-3J/GrsrJ J:224655 View
sclerosteosis 2 Lrp4tm1.1Pg/Lrp4tm1.1Pg involves: C57BL/6N J:277372 View
X-linked dominant hypophosphatemic rickets Fgf23tm1Blan/Fgf23+
PhexHyp/Y
Not Specified J:94041 View
X-linked dominant hypophosphatemic rickets Fgf23tm1Sliu/Fgf23+
PhexHyp/Y
involves: 129S/SvEv * C57BL/6 J:110579 View
X-linked dominant hypophosphatemic rickets Fgf23tm1Sliu/Fgf23tm1Sliu
PhexHyp/Y
involves: 129S/SvEv * C57BL/6 J:110579 View
X-linked dominant hypophosphatemic rickets Gy/Y involves: C3H/Sn * C57BL/6Ei J:38621, J:88352 View
X-linked dominant hypophosphatemic rickets PhexHyp-2J/Phex+ C57BL/6-PhexHyp-2J/J J:88352 View
X-linked dominant hypophosphatemic rickets PhexHyp-2J/Y C57BL/6-PhexHyp-2J/J J:88352 View
X-linked dominant hypophosphatemic rickets PhexHyp-Duk/Phex+ involves: BALB/cAnBomUrd J:88352 View
X-linked dominant hypophosphatemic rickets PhexHyp-Duk/Y involves: BALB/cAnBomUrd J:88352 View
X-linked dominant hypophosphatemic rickets PhexHyp/? involves: C57BL/6J J:99866 View
X-linked dominant hypophosphatemic rickets PhexHyp/Phex+ B6.Cg-PhexHyp/J J:88352 View
X-linked dominant hypophosphatemic rickets PhexHyp/Y B6.Cg-PhexHyp/J J:38621, J:67356, J:88352 View
X-linked dominant hypophosphatemic rickets Phexm1Jrt/Phex+ B6.129S1-PhexM1Jrt J:196537 View
X-linked dominant hypophosphatemic rickets Phexm1Jrt/Y B6.129S1-PhexM1Jrt J:196537 View
X-linked dominant hypophosphatemic rickets PhexMhdabap012/PhexMhdabap012 C3HeB/FeJ-PhexMhdabap012 J:183993 View
X-linked dominant hypophosphatemic rickets PhexMhdabap024/Phex+ C3HeB/FeJ-PhexMhdabap024 J:264682 View
X-linked dominant hypophosphatemic rickets PhexMhdabap024/PhexMhdabap024 C3HeB/FeJ-PhexMhdabap024 J:183993 View
X-linked dominant hypophosphatemic rickets PhexMhdabap024/Y C3HeB/FeJ-PhexMhdabap024 J:264682 View
X-linked dominant hypophosphatemic rickets PhexPug/Y involves: C57BL/6J J:136463 View
X-linked dominant hypophosphatemic rickets PhexSka1/Phex+ C57BL/6-PhexSka1 J:79953 View
X-linked dominant hypophosphatemic rickets PhexSka1/Y C57BL/6-PhexSka1 J:79953 View
      autosomal recessive hypophosphatemic rickets Dmp1tm1Mis/Dmp1tm1Mis involves: 129S7/SvEvBrd * CD-1 J:184352 View
autosomal recessive osteopetrosis 1 Ccdc154ntl/Ccdc154ntl involves: 129S7/SvEvBrd * C57BL/6J J:226596 View
bone remodeling disease Idh2tm1Jwpk/Idh2tm1Jwpk involves: 129S4/SvJae * C57BL/6 J:272241 View
Camurati-Engelmann disease Mitfmi-ew/Mitfmi-ew involves: C57BL/6Bn * NAW J:89821 View
craniometaphyseal dysplasia Anktm1.1Ejr/Anktm1.1Ejr B6.129-Anktm1.1Ejr J:168526 View
hereditary multiple exostoses Ext2tm1Werb/Ext2+ involves: C57BL/6 J:103125 View
osteopetrosis Csf1op/Csf1op B6C3Fe a/a-Csf1op/J J:26978 View
osteopetrosis Lrrk1tm1.1Smo/Lrrk1tm1.1Smo involves: 129S/Sv J:208677 View
osteopetrosis MitfMi-Or/MitfMi-Or involves: 101/Rl * C3H/Rl J:30149 View
osteoporosis Ciitatm1Wrth/Ciitatm1Wrth involves: 129P2/OlaHsd * C57BL/6 J:233241 View
osteoporosis Id4tm1Fsky/Id4tm1Fsky involves: 129P2/OlaHsd J:162236 View
osteoporosis Ifngr1tm1Agt/Ifngr1tm1Agt B6.129S7-Ifngr1tm1Agt/J J:233116 View
osteoporosis Irak3tm1Flv/Irak3tm1Flv involves: 129S1/Sv * C57BL/6 J:98035 View
osteoporosis Ly6atm1Pmf/Ly6atm1Pmf C.129P2-Ly6atm1Pmf J:83409 View
osteoporosis Pls3em2Bult/Pls3em2Bult C57BL/6J-Pls3em2Bult/BultJ J:341714 View
osteoporosis Pls3em2Bult/Y C57BL/6J-Pls3em2Bult/BultJ J:341714 View
osteoporosis Terctm1Rdp/Terctm1Rdp B6J.Cg-Terctm1Rdp J:213181 View
osteoporosis Terctm1Rdp/Terctm1Rdp
Wrntm1Lgu/Wrntm1Lgu
involves: 129/Sv * BALB/c * C57BL/6 * SLJ J:213181 View
osteoporosis Tnfrsf11btm1Khs/Tnfrsf11btm1Khs involves: 129P2/OlaHsd * C57BL/6 J:48325 View
osteoporosis Vdrtm1Ska/Vdrtm1Ska involves: C57BL/6NCrlj * CBA/JNCrlj J:83237 View
Paget's disease of bone Inpp5dtm1Rkh/Inpp5dtm1Rkh involves: 129S1/Sv * 129X1/SvJ J:78771 View
rickets Fam20ctm1.1Cqi/Fam20ctm1.1Cqi
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA J:185208 View
SOST-related sclerosing bone dysplasia Sosttm1(KOMP)Vlcg/Sosttm1(KOMP)Vlcg involves: C57BL/6NTac J:188586 View
Transgenes and
Other Mutations
     autosomal dominant hypophosphatemic rickets Tg(APOE-FGF23*R176Q)#Ack/0 involves: C57BL/6J * CBA J:93981 View
autosomal recessive hypophosphatemic rickets Tg(APOE-FGF23*R176Q)#Ack/0 involves: C57BL/6J * CBA J:192371 View
osteoporosis Tg(CD4-CIITA)357Ccum/? involves: C57BL/6 * C57BL/6J * SJL J:233241 View
osteoporosis Tg(TNFSF11)5519Edou/0 involves: C57BL/6J * CBA/J J:233240 View
SOST-related sclerosing bone dysplasia Rr20tm1.1Vlcg/Rr20tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac J:188586 View
SOST-related sclerosing bone dysplasia Tg(RP11-209M4)AGglo/0 FVB-Tg(RP11-209M4)4Gglo J:99965 View
SOST-related sclerosing bone dysplasia Tg(RP11-209M4)AGglo/Tg(RP11-209M4)AGglo FVB-Tg(RP11-209M4)4Gglo J:99965 View
X-linked dominant hypophosphatemic rickets Tg(APOE-FGF23*R176Q)#Ack/0 involves: C57BL/6J * CBA J:93981 View
X-linked dominant hypophosphatemic rickets Tg(Col1a1-FGF2*,-Sapphire)203Mmh/Tg(Col1a1-FGF2*,-Sapphire)203Mmh involves: FVB/N J:240777 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      Paget's disease of bone Sqstm1tm1Jjw/Sqstm1tm1Jjw involves: 129 * C57BL/6 J:141179 View