| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | alpha thalassemia-X-linked intellectual disability syndrome | ATRX* | Atrx* | 3 models | Alliance of Genome Resources | ||
| aplastic anemia | IFNG* | Ifng* | 1 model | Alliance of Genome Resources | |||
| beta thalassemia | HBB*, HBD | Hbb-b1*, Hbb-b2, Hbb-bh2, Hbb-bs, Hbb-bt | 17 models | Alliance of Genome Resources | |||
| congenital nonspherocytic hemolytic anemia | GPI* | Gpi1* | 2 models | Alliance of Genome Resources | |||
| Diamond-Blackfan anemia 6 | RPL5* | Rpl5* | 1 model | Alliance of Genome Resources | |||
| Diamond-Blackfan anemia 7 | RPL11* | Rpl11* | 1 model | Alliance of Genome Resources | |||
| Fanconi anemia complementation group A | FANCA* | Fanca* | 3 models | Alliance of Genome Resources | |||
| Fanconi anemia complementation group C | FANCC* | Fancc* | 2 models | Alliance of Genome Resources | |||
| Fanconi anemia complementation group D1 | BRCA2* | Brca2* | 1 model | Alliance of Genome Resources | |||
| Fanconi anemia complementation group D2 | FANCD2* | Fancd2* | 6 models | Alliance of Genome Resources | |||
| hereditary spherocytosis type 1 | ANK1* | Ank1* | 4 models | Alliance of Genome Resources | |||
| hereditary spherocytosis type 3 | SPTA1* | Spta1* | 5 models | Alliance of Genome Resources | |||
| pyruvate kinase deficiency of red cells | PKLR* | Pklr* | 2 models | Alliance of Genome Resources | |||
| | aplastic anemia | RASA3 | Rasa3* | 1 model | Alliance of Genome Resources | ||
| autoimmune hemolytic anemia | TSLP | Tslp* | 1 model | Alliance of Genome Resources | |||
| beta thalassemia | KLF1 | Klf1* | 1 model | Alliance of Genome Resources | |||
| congenital dyserythropoietic anemia | MAN2A1 | Man2a1* | 1 model | Alliance of Genome Resources | |||
| congenital dyserythropoietic anemia | DIAPH3 | Diaph3* | 1 model | Alliance of Genome Resources | |||
| Diamond-Blackfan anemia | RPSA | Rpsa* | 1 model | Alliance of Genome Resources | |||
| Diamond-Blackfan anemia | FLVCR1 | Flvcr1* | 2 models | Alliance of Genome Resources | |||
| Fanconi anemia | USP1 | Usp1* | 1 model | Alliance of Genome Resources | |||
| hereditary spherocytosis | KLF1 | Klf1* | 1 model | Alliance of Genome Resources | |||
| hereditary spherocytosis type 1 | ADD2 | Add2* | 1 model | Alliance of Genome Resources | |||
| hereditary spherocytosis type 1 | SPTA1 | Spta1* | 3 models | Alliance of Genome Resources | |||
| hereditary spherocytosis type 1 | EPB42 | Epb42* | 1 model | Alliance of Genome Resources | |||
| hereditary spherocytosis type 4 | SLC4A1 | Slc4a1* | 1 model | Alliance of Genome Resources | |||
| macrocytic anemia | KIT | Kit* | 3 models | Alliance of Genome Resources | |||
| microcytic anemia | DNM2 | Dnm2* | 1 model | Alliance of Genome Resources | |||
| pancytopenia | NUDT15 | Nudt15* | 2 models | Alliance of Genome Resources | |||
| thalassemia | PPP1R15A | Ppp1r15a* | 1 model | Alliance of Genome Resources | |||
| | alpha thalassemia | GPX1* | Gpx1 | Alliance of Genome Resources | |||
| alpha thalassemia | HBA1*, HBA2* | Hba-a1, Hba-a2 | 7 models | Alliance of Genome Resources | |||
| alpha thalassemia | HBB*, HBD | Hbb-b1, Hbb-b2, Hbb-bh2, Hbb-bs, Hbb-bt | Alliance of Genome Resources | ||||
| anemia | ITPA* | Itpa | Alliance of Genome Resources | ||||
| anemia | ACE* | Ace | Alliance of Genome Resources | ||||
| anemia | HK1* | Hk1 | Alliance of Genome Resources | ||||
| anemia | GPX1* | Gpx1 | Alliance of Genome Resources | ||||
| anemia | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
| anemia | G6PD* | G6pd2, G6pdx | Alliance of Genome Resources | ||||
| anemia | ERCC1* | Ercc1 | Alliance of Genome Resources | ||||
| anemia | EPOR* | Epor | Alliance of Genome Resources | ||||
| anemia | ANK1* | Ank1 | Alliance of Genome Resources | ||||
| anemia | EPHX1* | Ephx1 | Alliance of Genome Resources | ||||
| anemia | TF* | Trf | Alliance of Genome Resources | ||||
| anemia | SLC11A2* | Slc11a2 | Alliance of Genome Resources | ||||
| anemia | PON1* | Pon1 | Alliance of Genome Resources | ||||
| anemia | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| aplastic anemia | TNF* | Tnf | Alliance of Genome Resources | ||||
| aplastic anemia | SBDS* | Sbds | Alliance of Genome Resources | ||||
| aplastic anemia | TGFB1* | Tgfb1 | Alliance of Genome Resources | ||||
| aplastic anemia | THPO* | Thpo | Alliance of Genome Resources | ||||
| aplastic anemia | DKC1* | Dkc1 | Alliance of Genome Resources | ||||
| aplastic anemia | EPHX1* | Ephx1 | Alliance of Genome Resources | ||||
| aplastic anemia | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| aplastic anemia | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| aplastic anemia | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| aplastic anemia | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| aplastic anemia | NBN* | Nbn | Alliance of Genome Resources | ||||
| aplastic anemia | PRF1* | Prf1 | Alliance of Genome Resources | ||||
| autoimmune hemolytic anemia | CTLA4* | Ctla4 | Alliance of Genome Resources | ||||
| autosomal dominant beta thalassemia | HBB*, HBD | Hbb-b1, Hbb-b2, Hbb-bh2, Hbb-bs, Hbb-bt | Alliance of Genome Resources | ||||
| autosomal dominant sideroblastic anemia 4 | HSPA9* | Hspa9 | Alliance of Genome Resources | ||||
| autosomal recessive pyridoxine-refractory sideroblastic anemia 2 | SLC25A38* | Slc25a38 | Alliance of Genome Resources | ||||
| autosomal recessive pyridoxine-refractory sideroblastic anemia 3 | GLRX5* | Glrx5 | Alliance of Genome Resources | ||||
| beta thalassemia | HFE* | Hfe | Alliance of Genome Resources | ||||
| beta thalassemia | HBS1L* | Hbs1l | Alliance of Genome Resources | ||||
| beta thalassemia | TNF* | Tnf | Alliance of Genome Resources | ||||
| beta thalassemia | COL1A1* | Col1a1 | Alliance of Genome Resources | ||||
| beta thalassemia | GATA1* | Gata1 | Alliance of Genome Resources | ||||
| beta thalassemia | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
| beta thalassemia | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| beta thalassemia | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| beta thalassemia | BCL11A* | Bcl11a | Alliance of Genome Resources | ||||
| congenital dyserythropoietic anemia | RACGAP1* | Racgap1 | Alliance of Genome Resources | ||||
| congenital dyserythropoietic anemia | CDAN1* | Cdan1 | Alliance of Genome Resources | ||||
| congenital dyserythropoietic anemia type Ia | CDAN1* | Cdan1 | Alliance of Genome Resources | ||||
| congenital dyserythropoietic anemia type Ib | CDIN1* | Cdin1 | Alliance of Genome Resources | ||||
| congenital dyserythropoietic anemia type II | SEC23B* | Sec23b | Alliance of Genome Resources | ||||
| congenital dyserythropoietic anemia type III | KIF23* | Kif23 | 2 "NOT" models | Alliance of Genome Resources | |||
| congenital dyserythropoietic anemia type IV | KLF1* | Klf1 | Alliance of Genome Resources | ||||
| congenital hemolytic anemia | GPI* | Gpi1 | Alliance of Genome Resources | ||||
| congenital hemolytic anemia | HBB*, HBD | Hbb-b1, Hbb-b2, Hbb-bh2, Hbb-bs, Hbb-bt | Alliance of Genome Resources | ||||
| congenital hemolytic anemia | SLC4A1* | Slc4a1 | Alliance of Genome Resources | ||||
| congenital nonspherocytic hemolytic anemia | PKLR* | Pklr | Alliance of Genome Resources | ||||
| congenital nonspherocytic hemolytic anemia | AK1* | Ak1 | Alliance of Genome Resources | ||||
| congenital nonspherocytic hemolytic anemia | G6PD* | G6pd2, G6pdx | Alliance of Genome Resources | ||||
| congenital nonspherocytic hemolytic anemia | HK1* | Hk1 | Alliance of Genome Resources | ||||
| dehydrated hereditary stomatocytosis 1 | PIEZO1* | Piezo1 | Alliance of Genome Resources | ||||
| dehydrated hereditary stomatocytosis 2 | KCNN4* | Kcnn4 | Alliance of Genome Resources | ||||
| delta beta-thalassemia | HBB*, HBD | Hbb-b1, Hbb-b2, Hbb-bh2, Hbb-bs, Hbb-bt | Alliance of Genome Resources | ||||
| delta beta-thalassemia | HBG1*, HBG2*, HBE1 | Hbb-bh0, Hbb-bh1, Hbb-y | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia | GH1*, CSH1, CSH2, CSHL1, GH2 | Gh | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia | HEATR3* | Heatr3 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia | RPS19* | Rps19 | 4 models | Alliance of Genome Resources | |||
| Diamond-Blackfan anemia 1 | RPS19* | Rps19 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 10 | RPS26* | Rps26 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 11 | RPL26* | Rpl26 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 12 | RPL15* | Rpl15 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 13 | RPS29* | Rps29 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 14 with mandibulofacial dysostosis | TSR2* | Tsr2 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 15 with mandibulofacial dysostosis | RPS28* | Rps28 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 16 | RPL27* | Rpl27 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 17 | RPS27* | Rps27, Rps27rt | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 18 | RPL18* | Rpl18 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 19 | RPL35* | Rpl35, Rpl35rt | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 20 | RPS15A* | Rps15a | Alliance of Genome Resources | ||||
| Diamond-blackfan anemia 3 | RPS24* | Rps24 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 4 | RPS17* | Rps17 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 5 | RPL35A* | Rpl35a | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 8 | RPS7* | Rps7 | Alliance of Genome Resources | ||||
| Diamond-Blackfan anemia 9 | RPS10* | Rps10 | Alliance of Genome Resources | ||||
| Fanconi anemia | BRCA1* | Brca1 | Alliance of Genome Resources | ||||
| Fanconi anemia | RFWD3* | Rfwd3 | Alliance of Genome Resources | ||||
| Fanconi anemia | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| Fanconi anemia | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| Fanconi anemia | FANCI* | Fanci | Alliance of Genome Resources | ||||
| Fanconi anemia | FANCG* | Fancg | Alliance of Genome Resources | ||||
| Fanconi anemia | FANCD2* | Fancd2 | Alliance of Genome Resources | ||||
| Fanconi anemia | FANCC* | Fancc | Alliance of Genome Resources | ||||
| Fanconi anemia | FANCA* | Fanca | Alliance of Genome Resources | ||||
| Fanconi anemia | BRCA2* | Brca2 | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group B | FANCB* | Fancb | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group E | FANCE* | Fance | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group F | FANCF* | Fancf | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group G | FANCG* | Fancg | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group I | FANCI* | Fanci | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group J | BRIP1* | Brip1 | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group L | FANCL* | Fancl | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group N | PALB2* | Palb2 | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group O | RAD51C* | Rad51c | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group P | SLX4* | Slx4 | 1 "NOT" model | Alliance of Genome Resources | |||
| Fanconi anemia complementation group Q | ERCC4* | Ercc4 | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group R | RAD51* | Rad51 | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group T | UBE2T* | Ube2t | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group U | XRCC2* | Xrcc2 | Alliance of Genome Resources | ||||
| Fanconi anemia complementation group V | MAD2L2* | Mad2l2 | Alliance of Genome Resources | ||||
| fetal erythroblastosis | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| Heinz body anemia | HBA1*, HBA2* | Hba-a1, Hba-a2 | Alliance of Genome Resources | ||||
| Heinz body anemia | HBB*, HBD | Hbb-b1, Hbb-b2, Hbb-bh2, Hbb-bs, Hbb-bt | Alliance of Genome Resources | ||||
| hemoglobin C disease | HBB*, HBD | Hbb-b1, Hbb-b2, Hbb-bh2, Hbb-bs, Hbb-bt | Alliance of Genome Resources | ||||
| hemoglobin H disease | HBA1*, HBA2* | Hba-a1, Hba-a2 | Alliance of Genome Resources | ||||
| hemoglobinopathy | HBB*, HBD | Hbb-b1, Hbb-b2, Hbb-bh2, Hbb-bs, Hbb-bt | Alliance of Genome Resources | ||||
| hemolytic anemia | AK1* | Ak1 | Alliance of Genome Resources | ||||
| hemolytic anemia | FCGR2A*, FCGR2B, FCGR2C | Fcgr2b, Fcgr3 | Alliance of Genome Resources | ||||
| hemolytic anemia | GCLC* | Gclc | Alliance of Genome Resources | ||||
| hemolytic anemia | HP*, HPR | Hp | Alliance of Genome Resources | ||||
| hemolytic anemia | ITPA* | Itpa | Alliance of Genome Resources | ||||
| hemolytic anemia | PGK1* | Pgk1 | Alliance of Genome Resources | ||||
| hemolytic anemia | RHAG* | Rhag | Alliance of Genome Resources | ||||
| hemolytic anemia | ABO* | Abo | Alliance of Genome Resources | ||||
| hereditary spherocytosis | EPB42* | Epb42 | Alliance of Genome Resources | ||||
| hereditary spherocytosis | ANK1* | Ank1 | Alliance of Genome Resources | ||||
| hereditary spherocytosis | SPTB* | Sptb | Alliance of Genome Resources | ||||
| hereditary spherocytosis | SPTA1* | Spta1 | Alliance of Genome Resources | ||||
| hereditary spherocytosis | SLC4A1* | Slc4a1 | Alliance of Genome Resources | ||||
| hereditary spherocytosis type 2 | SPTB* | Sptb | Alliance of Genome Resources | ||||
| hereditary spherocytosis type 5 | EPB42* | Epb42 | Alliance of Genome Resources | ||||
| hypochromic anemia | SLC11A2* | Slc11a2 | Alliance of Genome Resources | ||||
| hypochromic microcytic anemia | TNF* | Tnf | Alliance of Genome Resources | ||||
| megaloblastic anemia | TCN2* | Tcn2 | Alliance of Genome Resources | ||||
| megaloblastic anemia | AMN* | Amn | Alliance of Genome Resources | ||||
| megaloblastic anemia | SLC19A2* | Slc19a2 | Alliance of Genome Resources | ||||
| methemoglobinemia | CYB5A* | Cyb5a | Alliance of Genome Resources | ||||
| methemoglobinemia | CYB5R3* | Cyb5r3 | Alliance of Genome Resources | ||||
| microcytic anemia | TMPRSS6* | Tmprss6 | Alliance of Genome Resources | ||||
| overhydrated hereditary stomatocytosis | RHAG* | Rhag | Alliance of Genome Resources | ||||
| pancytopenia | FANCC* | Fancc | Alliance of Genome Resources | ||||
| pure red-cell aplasia | HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5 | H2-Eb1, H2-Eb2 | Alliance of Genome Resources | ||||
| pure red-cell aplasia | HLA-DQB1*, HLA-DQB2 | H2-Ab1 | Alliance of Genome Resources | ||||
| Rh deficiency syndrome | RHAG* | Rhag | 2 "NOT" models | Alliance of Genome Resources | |||
| sideroblastic anemia | CALR* | Calr | Alliance of Genome Resources | ||||
| sideroblastic anemia | HSCB* | Hscb | Alliance of Genome Resources | ||||
| sideroblastic anemia | ALAS2* | Alas2 | Alliance of Genome Resources | ||||
| sideroblastic anemia 1 | ALAS2* | Alas2 | Alliance of Genome Resources | ||||
| sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay | TRNT1* | Trnt1 | Alliance of Genome Resources | ||||
| thalassemia | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| X-linked congenital hemolytic anemia | ATP11C* | Atp11c | Alliance of Genome Resources | ||||
| X-linked dyserythropoietic anemia | GATA1* | Gata1 | Alliance of Genome Resources | ||||
| X-linked sideroblastic anemia with ataxia | ABCB7* | Abcb7 | Alliance of Genome Resources | ||||
Excel File
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Transgenes and other genome features developed in mice to model this disease.
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| alpha thalassemia | Hba | 8 models | |
| autoimmune hemolytic anemia | Tg(tetO/CMV-Tslp)#Sfz | 1 model | |
| beta thalassemia | Rr320 | 2 models | |
| beta thalassemia | Hbb | 6 models | |
| Diamond-Blackfan anemia | Tg(CAG-RPS19*R62W)#Dmb | 1 model | |