Rpl15 MGI Mouse Gene Detail - MGI:1913730

Symbol

Rpl15
Name

ribosomal protein L15
Synonyms

2510008H07Rik

Feature Type

protein coding gene
IDs

MGI:1913730
NCBI Gene: 66480
Alliance

genome feature page
Transcription Start Sites

3 TSS

Sequence Map

Chr14:4198710-4201873 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 7.08 cM
Mapping Data

1 experiment

SNPs within 2kb

139 from dbSNP Build 142
Strain Annotations

25

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913730	protein coding gene	Chr14:4198305-4201873 (+)
129S1/SvImJ	ENSMUSG00200045717	protein coding gene	Chr9:19051402-19066387 (-)
129S1/SvImJ	ENSMUSG00200024250	protein coding gene	Chr14:829802-833369 (+)
A/J	ENSMUSG00195029038	protein coding gene	Chr14:1695521-1699090 (+)
A/J	ENSMUSG00195032222	protein coding gene	Chr9:18888083-18903065 (-)
AKR/J	ENSMUSG00220025436	protein coding gene	Chr9:18890485-18905474 (-)
AKR/J	ENSMUSG00220023027	protein coding gene	Chr14:786368-789936 (+)
BALB/cJ	ENSMUSG00180023206	protein coding gene	Chr14:997376-1000946 (+)
BALB/cJ	ENSMUSG00180041677	protein coding gene	Chr9:19022355-19037339 (-)
C3H/HeJ	ENSMUSG00175039652	protein coding gene	Chr9:18984870-18999854 (-)
C3H/HeJ	ENSMUSG00175009011	protein coding gene	Chr14:987206-990773 (+)
C57BL/6NJ	ENSMUSG00215016200	protein coding gene	Chr14:1231417-1234986 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018973	protein coding gene	Chr14:11067993-11071563 (-)
CAST/EiJ	ENSTCUG00005029566	protein coding gene	Chr14:989505-993074 (+)
CBA/J	ENSMUSG00210043308	protein coding gene	Chr9:18965790-18980773 (-)
CBA/J	ENSMUSG00210009225	protein coding gene	Chr11:18455080-18456954 (-)
CBA/J	ENSMUSG00210032377	protein coding gene	Chr14:1208806-1212373 (+)
DBA/2J	ENSMUSG00185036148	protein coding gene	Chr14:1214261-1217828 (+)
DBA/2J	ENSMUSG00185025150	protein coding gene	Chr9:19080990-19096080 (-)
FVB/NJ	ENSMUSG00205017202	protein coding gene	Chr14:1175355-1178923 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230005899	protein coding gene	Chr14:2343832-2347399 (+)
NOD/ShiLtJ	ENSMUSG00190008126	protein coding gene	Chr11:18611341-18613182 (-)
NOD/ShiLtJ	ENSMUSG00190031563	protein coding gene	Chr14:1216398-1219966 (+)
NZO/HlLtJ	ENSMUSG00225036844	protein coding gene	Chr14:1653238-1656804 (+)
PWK/PhJ	no annotation
SPRET/EiJ	ENSMSPG00010002380	protein coding gene	Chr14:1348296-1350724 (+)
WSB/EiJ	no annotation

Human Ortholog

RPL15, ribosomal protein L15

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPL15, ribosomal protein L15
Synonyms

DBA12, EC45, eL15, L15, RPL10, RPLY10, RPYL10
Links

HGNC:10306

NCBI Gene ID: 6138

UniProt: P61313
Chr Location

3p24.2; chr3:23916545-23924631 (+) GRCh38

MGI Vertebrate Homology

Rpl15 stringent orthology
1 human;1 mouse;2 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPL15
Gene Tree

Rpl15

Diseases

1 with human RPL15 associations

				Human Disease	Mouse Models
				Diamond-Blackfan anemia 12 IDs Diamond-Blackfan anemia 12 DOID:0111882 OMIM:615550

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

3 phenotype references

All Mutations and Alleles

13
Gene trapped

13
Find Mice (IMSR)

7 strains or lines available

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All GO Annotations

40
GO References

12

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

618
Tissues

14
cDNA Data

23
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rpl15

ZFIN rpl15

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All Sequences

86
RefSeq

6
UniProt

4
CCDS

CCDS36812.1

Ensembl

ENSMUSG00000012405 (Evidence)
NCBI Gene

66480

			Length	Strain/Species	Flank
genomic	66480	NCBI Gene Model \| MGI Sequence Detail	3164	C57BL/6J	± kb
transcript	NM_001359897	RefSeq \| MGI Sequence Detail	1989	C57BL/6
polypeptide	Q9CZM2	UniProt \| EBI \| MGI Sequence Detail	204	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000014195 large ribosomal subunit protein eL15

(term hierarchy)
PDB

6SWA, 7CPU, 7CPV, 7LS1, 7LS2, 9H4N, 9QOH, 9QQL, 9QQP, 9QSA, 9QWT
InterPro Domains

IPR000439 Large ribosomal subunit protein eL15

IPR020925 Large ribosomal subunit protein eL15, conserved site

IPR024794 Large ribosomal subunit protein eL15 core domain superfamily

IPR012678 Ribosomal protein uL23/eL15/eS24 core domain superfamily
GlyGen

Q9CZM2 1 site, 1 O-linked glycan (1 site)

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All nucleic 24

cDNA 24

Microarray probesets 11

Summaries

All 37

Developmental Gene Expression 4

Gene Ontology 12

Phenotypes 3
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

TSS for Rpl15:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr127528	Chr14:4198491-4198505 (+)	-212 bp
Tssr127527	Chr14:4198621-4198632 (+)	-83 bp
Tssr127526	Chr14:4198705-4198743 (+)	14 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24