Pdgfratm1.1(cre/Esr1*)Nshk/Pdgfra+
Runx1tm1Medv/Runx1tm1Medv
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj
|
abnormal hematopoietic cell number |
J:193389
|
|
anemia |
J:193389
|
|
embryonic lethality during organogenesis, complete penetrance |
J:193389
|
|
pallor |
J:193389
|
Runx1tm1(cre/Esr1*)Ims/Runx1+
either: (involves: C57BL/6 * CBA) or (involves: C57BL/6 * CBA * ICR)
|
normal
hematopoietic system phenotype |
J:121435
|
Runx1tm1(cre/Esr1*)Ims/Runx1tm1(cre/Esr1*)Ims
involves: C57BL/6 * CBA
|
neonatal lethality |
J:182232
|
Runx1tm1(RUNX1)Gcg/Runx1tm1(RUNX1)Gcg
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA
|
abnormal granulocyte differentiation |
J:106800
|
|
abnormal myelopoiesis |
J:106801
|
|
abnormal T cell differentiation |
J:106800
|
|
anemia |
J:106800
|
|
decreased CD4-positive, alpha-beta T cell number |
J:106800
|
|
decreased double-positive T cell number |
J:106800
|
|
increased CD8-positive, alpha-beta T cell number |
J:106800
|
|
increased metastatic potential |
J:106800
|
|
increased T cell derived lymphoma incidence |
J:106800
|
Runx1tm1.1Glac/Runx1tm1.1Glac
involves: 129P2/OlaHsd * C57BL/6 * ICR
|
normal
embryo phenotype |
J:155698
|
|
normal
hematopoietic system phenotype |
J:155698
|
|
normal
mortality/aging |
J:155698
|
Runx1tm1.1Gss/Runx1tm1.1Gss
involves: 129S4/SvJae * C57BL/6
|
abnormal definitive hematopoiesis |
J:157660
|
|
decreased hematopoietic stem cell number |
J:157660
|
|
embryonic lethality during organogenesis, complete penetrance |
J:157660
|
|
hemorrhage |
J:157660
|
|
pale liver |
J:157660
|
Runx1tm1.1Medv/Runx1tm1.1Medv
involves: 129P2/OlaHsd
|
no abnormal phenotype detected |
J:106769
|
Runx1tm1.1Stkd/Runx1tm1.1Stkd
Tg(Col2a1-cre)1Star/0
involves: C57BL/6
|
normal
skeleton phenotype |
J:158761
|
Runx1tm1.1Stkd/Runx1tm1.1Stkd
Tg(Prrx1-cre)1Cjt/0
involves: C57BL/6J * SJL/J
|
abnormal bone mineralization |
J:158761
|
|
abnormal skeleton development |
J:158761
|
|
abnormal sternum morphology |
J:158761
|
|
abnormal xiphoid process morphology |
J:158761
|
Runx1tm1Buch/Runx1tm1Buch
involves: 129P2/OlaHsd
|
no abnormal phenotype detected |
J:68499
|
Runx1tm1Dow/Runx1+
involves: 129P2/OlaHsd * C57BL/6
|
no abnormal phenotype detected |
J:31130
|
Runx1tm1Dow/Runx1tm1Dow
involves: 129P2/OlaHsd * C57BL/6
|
abnormal embryonic hematopoiesis |
J:31130
|
|
embryonic lethality during organogenesis, complete penetrance |
J:31130
|
|
hemopericardium |
J:31130
|
|
hemoperitoneum |
J:31130
|
|
internal hemorrhage |
J:31130
|
|
intraventricular hemorrhage |
J:31130
|
|
pale liver |
J:31130
|
Runx1tm1Itan/Runx1tm1Itan
involves: 129P2/OlaHsd
|
normal
hematopoietic system phenotype |
J:132661
|
|
normal
immune system phenotype |
J:132661
|
Runx1tm1Medv/Runx1tm1Medv
involves: 129P2/OlaHsd
|
anemia |
J:106769
|
|
embryonic lethality during organogenesis, complete penetrance |
J:106769
|
|
hemorrhage |
J:106769
|
|
impaired hematopoiesis |
J:106769
|
Runx1tm1Sata/Runx1tm1Sata
involves: 129S4/SvJae * C57BL/6J
|
abnormal angiogenesis |
J:63424
|
|
abnormal definitive hematopoiesis |
J:50937,
J:63424
|
|
abnormal erythropoiesis |
J:63424
|
|
abnormal vascular branching morphogenesis |
J:63424
|
|
abnormal vitelline vascular remodeling |
J:63424
|
|
aneurysm |
J:63424
|
|
embryonic lethality during organogenesis, complete penetrance |
J:50937
|
|
hemopericardium |
J:63424
|
|
internal hemorrhage |
J:63424
|
|
intraventricular hemorrhage |
J:63424
|
Runx1tm1Sata/Runx1tm1Sata
Tg(Rr438-Runx1)#Mym/0
involves: 129S4/SvJae * C57BL/6 * DBA/2
|
abnormal nasal septum morphology |
J:145189
|
|
abnormal palatal shelf fusion at midline |
J:145189
|
|
abnormal palatal shelf morphology |
J:145189
|
|
abnormal primary and secondary palatal fusion |
J:145189
|
|
anterior cleft palate |
J:145189
|
|
lethality throughout fetal growth and development |
J:145189
|
Runx1tm1Soga/Runx1tm1.1Soga
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA
|
abnormal B cell differentiation |
J:88511
|
|
abnormal common myeloid progenitor cell morphology |
J:88511
|
|
abnormal definitive hematopoiesis |
J:88511
|
|
abnormal megakaryocyte differentiation |
J:88511
|
|
abnormal megakaryocyte morphology |
J:88511
|
|
abnormal megakaryocyte progenitor cell morphology |
J:88511
|
|
abnormal T cell differentiation |
J:88511
|
|
normal
hematopoietic system phenotype |
J:88511
|
|
thrombocytopenia |
J:88511
|
Runx1tm1Spe/Runx1+
either: (involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA/Ca) or (involves: 129S4/SvJae * C57BL/6 * CBA/Ca)
|
increased T cell derived lymphoma incidence |
J:80829
|
Runx1tm1Spe/Runx1+
either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)
|
abnormal embryonic hematopoiesis |
J:120100
|
|
decreased CD4-positive, alpha-beta T cell number |
J:120100
|
|
normal
neoplasm |
J:80829
|
Runx1tm1Spe/Runx1tm1Spe
either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)
|
abnormal erythropoiesis |
J:35115
|
|
embryo tissue necrosis |
J:35115
|
|
embryonic lethality during organogenesis, complete penetrance |
J:35115
|
|
hemopericardium |
J:35115
|
|
hemorrhage |
J:35115
|
|
impaired hematopoiesis |
J:35115
|
|
impaired myelopoiesis |
J:35115
|
|
increased nucleated erythrocyte cell number |
J:35115
|
|
internal hemorrhage |
J:35115
|
Runx1tm1Spe/Runx1tm1Yg
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
|
anemia |
J:160791
|
|
embryonic lethality |
J:160791
|
|
internal hemorrhage |
J:160791
|
Runx1tm1Spe/Runx1tm2Spe
either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)
|
abnormal embryonic hematopoiesis |
J:56184
|
Runx1tm1Spe/Runx1tm3Itan
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
normal
hematopoietic system phenotype |
J:160791
|
|
normal
mortality/aging |
J:160791
|
Runx1tm1Tani/Runx1tm1Tani
Tg(Cd4-cre)1Cwi/?
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal CD4-positive T cell differentiation |
J:125959
|
|
abnormal CD8-positive, alpha-beta T cell differentiation |
J:125959
|
|
abnormal double-positive T cell morphology |
J:125959
|
|
decreased CD4-positive, alpha-beta T cell number |
J:125959
|
Runx1tm1Tani/Runx1tm1Tani
Tg(Lck-cre)1Cwi/?
involves: 129P2/OlaHsd
|
arrested T cell differentiation |
J:125959
|
|
decreased double-positive T cell number |
J:125959
|
|
decreased thymocyte number |
J:125959
|
|
increased double-negative T cell number |
J:125959
|
Runx1tm1Yg/Runx1+
Tg(Runx1-GFP)#Itan/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal dorsal aorta morphology |
J:160791
|
|
abnormal hematopoietic system morphology/development |
J:160791
|
Runx1tm1Yg/Runx1tm1Yg
either: (involves: 129/Sv * 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1)
|
abnormal definitive hematopoiesis |
J:125830
|
|
abnormal leukopoiesis |
J:125830
|
|
abnormal T cell differentiation |
J:125830
|
|
abnormal thymus corticomedullary boundary morphology |
J:125830
|
|
abnormal thymus lobule morphology |
J:125830
|
|
decreased body size |
J:125830
|
|
decreased single-positive T cell number |
J:125830
|
|
decreased thymocyte number |
J:125830
|
|
increased double-positive T cell number |
J:125830
|
|
increased thymocyte apoptosis |
J:125830
|
|
postnatal lethality, complete penetrance |
J:125830
|
|
slow postnatal weight gain |
J:125830
|
|
small thymus |
J:125830
|
|
thymus cyst |
J:125830
|
|
thymus hypoplasia |
J:125830
|
Runx1tm1Yg/Runx1tm1Yg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal bone marrow cell morphology/development |
J:160791
|
Runx1tm1Yg/Runx1tm1Yg
Tg(Lck-cre)1Jtak/?
either: (involves: 129/Sv * 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1)
|
decreased T cell number |
J:125830
|
Runx1tm1Yg/Runx1tm1Yg
Tg(Runx1-GFP)#Itan/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal dorsal aorta morphology |
J:160791
|
|
abnormal hematopoietic system morphology/development |
J:160791
|
Runx1tm1Yg/Runx1tm2Spe
either: (involves: 129/Sv) or (involves: 129/Sv * ICR) or (involves: 129/Sv * MF1)
|
embryonic lethality during organogenesis, complete penetrance |
J:125830
|
|
internal hemorrhage |
J:125830
|
|
intracranial hemorrhage |
J:125830
|
|
spinal hemorrhage |
J:125830
|
Runx1tm2.1(cre/Esr1*)Ims/Runx1tm1Medv
involves: 129P2/OlaHsd * C57BL/6
|
abnormal hematopoietic system morphology/development |
J:182232
|
|
anemia |
J:182232
|
|
embryonic lethality during organogenesis, complete penetrance |
J:182232
|
|
normal
hematopoietic system phenotype |
J:182232
|
|
hemorrhage |
J:182232
|
|
neonatal lethality |
J:182232
|
Runx1tm2.1(cre/Esr1*)Ims/Runx1tm2.1(cre/Esr1*)Ims
involves: C57BL/6
|
anemia |
J:182232
|
|
embryonic lethality during organogenesis, complete penetrance |
J:182232
|
|
hemorrhage |
J:182232
|
Runx1tm2.1Gss/Runx1tm2.1Gss
involves: 129S4/SvJae * C57BL/6
|
abnormal definitive hematopoiesis |
J:214025
|
|
abnormal erythrocyte morphology |
J:214025
|
|
abnormal erythroid progenitor cell morphology |
J:214025
|
|
abnormal erythropoiesis |
J:214025
|
|
abnormal leukocyte morphology |
J:214025
|
|
abnormal megakaryocyte differentiation |
J:214025
|
|
abnormal megakaryocyte morphology |
J:214025
|
|
abnormal spleen white pulp morphology |
J:214025
|
|
anemia |
J:214025
|
|
decreased CD8-positive, alpha-beta T cell number |
J:214025
|
|
decreased hematocrit |
J:214025
|
|
decreased immature B cell number |
J:214025
|
|
decreased mean corpuscular volume |
J:214025
|
|
decreased pre-pro B cell number |
J:214025
|
|
enlarged spleen |
J:214025
|
|
normal
hematopoietic system phenotype |
J:214025
|
|
increased erythrocyte cell number |
J:214025
|
|
increased granulocyte number |
J:214025
|
|
increased hemoglobin content |
J:214025
|
|
increased macrophage cell number |
J:214025
|
|
increased mature B cell number |
J:214025
|
|
increased mean platelet volume |
J:214025
|
|
increased monocyte cell number |
J:214025
|
|
increased pro-B cell number |
J:214025
|
|
increased red blood cell distribution width |
J:214025
|
|
normal
mortality/aging |
J:214025
|
|
myeloid hyperplasia |
J:214025
|
|
thrombocytosis |
J:214025
|
Runx1tm2Buch/Runx1tm2Buch
involves: 129P2/OlaHsd * C57BL/6
|
no abnormal phenotype detected |
J:105709
|
Runx1tm2Buch/Runx1tm2Buch
Tg(Mx1-cre)1Cgn/?
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
abnormal common myeloid progenitor cell morphology |
J:105709
|
|
abnormal immune system organ morphology |
J:105709
|
|
abnormal leukocyte morphology |
J:105709
|
|
abnormal lymph node size |
J:105709
|
|
abnormal megakaryocyte morphology |
J:105709
|
|
abnormal thymus lobule morphology |
J:105709
|
|
decreased CD4-positive, alpha-beta T cell number |
J:105709
|
|
decreased CD8-positive, alpha-beta T cell number |
J:105709
|
|
decreased double-positive T cell number |
J:105709
|
|
decreased lymphocyte cell number |
J:105709
|
|
decreased mature B cell number |
J:105709
|
|
decreased megakaryocyte cell number |
J:105709
|
|
decreased spleen white pulp amount |
J:105709
|
|
decreased T cell number |
J:105709
|
|
decreased thymus weight |
J:105709
|
|
impaired myelopoiesis |
J:105709
|
|
increased hematopoietic stem cell number |
J:105709
|
|
increased lymphoma incidence |
J:105709
|
|
increased mast cell number |
J:105709
|
|
increased monocyte cell number |
J:105709
|
|
increased neutrophil cell number |
J:105709
|
|
increased number of Howell-Jolly bodies |
J:105709
|
|
increased spleen red pulp amount |
J:105709
|
|
increased spleen weight |
J:105709
|
|
increased T cell derived lymphoma incidence |
J:105709
|
|
small Peyer's patches |
J:105709
|
|
thrombocytopenia |
J:105709
|
Runx1tm2Dow/Runx1+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal embryonic hematopoiesis |
J:79160
|
|
embryonic lethality during organogenesis, complete penetrance |
J:79160
|
|
hemopericardium |
J:79160
|
|
intraventricular hemorrhage |
J:79160
|
|
pale liver |
J:79160
|
Runx1tm2Itan/Runx1tm2Itan
involves: 129P2/OlaHsd
|
normal
hematopoietic system phenotype |
J:132661
|
|
normal
immune system phenotype |
J:132661
|
Runx1tm2Spe/Runx1tm3Spe
Tg(KRT5-cre)5132Jlj/0
either: (involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2J) or (involves: 129S4/SvJae * C57BL/6 * DBA/2J)
|
abnormal coat appearance |
J:116050
|
|
abnormal zigzag hair morphology |
J:116050
|
|
decreased curvature of zigzag hairs |
J:116050
|
|
increased curvature of auchene hairs |
J:116050
|
Runx1tm3.1Spe/Runx1tm3.1Spe
involves: 129S4/SvJae * C57BL/6
|
no abnormal phenotype detected |
J:152374
|
Runx1tm3Itan/Runx1tm3Itan
involves: 129P2/OlaHsd
|
abnormal axillary lymph node morphology |
J:168918
|
|
abnormal inguinal lymph node morphology |
J:168918
|
|
abnormal lymph organ development |
J:168918
|
|
abnormal Peyer's patch morphology |
J:168918
|
|
decreased CD4-positive, alpha-beta T cell number |
J:168918
|
|
decreased Peyer's patch number |
J:168918
|
|
decreased thymocyte number |
J:168918
|
|
small Peyer's patches |
J:168918
|
Runx1tm3Itan/Runx1tm3Itan
involves: 129P2/OlaHsd * C57BL/6
|
abnormal bone marrow cell morphology/development |
J:160791
|
|
decreased leukocyte cell number |
J:160791
|
|
increased hematopoietic stem cell number |
J:160791
|
|
normal
mortality/aging |
J:160791
|
|
thrombocytopenia |
J:160791
|
Runx1tm3Itan/Runx1tm3Itan
Tg(Runx1-GFP)#Itan/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
abnormal dorsal aorta morphology |
J:160791
|
|
abnormal hematopoietic system morphology/development |
J:160791
|
Runx1tm3Spe/Runx1tm3Spe
involves: 129/Sv * C57BL/6
|
no abnormal phenotype detected |
J:90431
|
Runx1tm3Spe/Runx1tm3Spe
Slc17a8tm1(cre)Lowl/Slc17a8+
involves: 129S4/SvJae
|
normal
behavior/neurological phenotype |
J:193903
|
|
hypoalgesia |
J:193903
|
Runx1tm3Spe/Runx1tm3Spe
Tg(Cdh5-cre)1Spe/0
involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6
|
abnormal hematopoietic stem cell morphology |
J:145700
|
|
anemia |
J:145700
|
|
decreased hematopoietic stem cell number |
J:145700
|
|
internal hemorrhage |
J:145700
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:145700
|
|
pale liver |
J:145700
|
Runx1tm3Spe/Runx1tm3Spe
Tg(KRT5-cre)5132Jlj/0
either: (involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2J) or (involves: 129S4/SvJae * C57BL/6 * DBA/2J)
|
abnormal coat appearance |
J:116050
|
|
abnormal zigzag hair morphology |
J:116050
|
|
decreased curvature of zigzag hairs |
J:116050
|
|
increased curvature of auchene hairs |
J:116050
|
Runx1tm3Spe/Runx1tm3Spe
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA
|
abnormal myeloblast morphology/development |
J:151639
|
|
arrested T cell differentiation |
J:131217
|
|
decreased B cell number |
J:151639
|
|
decreased double-negative T cell number |
J:131217
|
|
decreased hematopoietic stem cell number |
J:151639
|
|
decreased thymus weight |
J:131217
|
|
increased double-negative T cell number |
J:131217
|
|
increased hematopoietic stem cell number |
J:151639
|
|
increased incidence of tumors by chemical induction |
J:267082
|
|
increased spleen weight |
J:131217
|
|
increased susceptibility to induced morbidity/mortality |
J:267082
|
|
thrombocytopenia |
J:131217
|
Runx1tm3Spe/Runx1tm3Spe
Tg(VAV1-cre)1Graf/0
involves: 129S4/SvJae
|
abnormal common myeloid progenitor cell morphology |
J:145700
|
|
abnormal platelet morphology |
J:145700
|
|
decreased B cell number |
J:145700
|
|
decreased double-positive T cell number |
J:145700
|
|
decreased lymphocyte cell number |
J:145700
|
|
decreased thymocyte number |
J:145700
|
|
increased granulocyte number |
J:145700
|
|
increased hematopoietic stem cell number |
J:145700
|
|
increased monocyte cell number |
J:145700
|
Runx1tm4Dow/Runx1tm4Dow
involves: 129P2/OlaHsd
|
no abnormal phenotype detected |
J:89055
|
Runx1tm4Spe/Runx1+
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
decreased CD4-positive, alpha-beta T cell number |
J:120100
|
Runx1tm4Spe/Runx1tm4Spe
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
decreased leukocyte cell number |
J:120100
|
|
decreased lymphocyte cell number |
J:120100
|
|
increased monocyte cell number |
J:120100
|
|
postnatal growth retardation |
J:120100
|
|
postnatal lethality, incomplete penetrance |
J:120100
|
|
thrombocytopenia |
J:120100
|
Runx1tm5Spe/Runx1+
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
decreased CD4-positive, alpha-beta T cell number |
J:120100
|
Runx1tm5Spe/Runx1tm5Spe
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
embryonic lethality during organogenesis, complete penetrance |
J:120100
|
|
hemopericardium |
J:120100
|
|
hemoperitoneum |
J:120100
|
|
intraventricular hemorrhage |
J:120100
|
Runx1tm6Spe/Runx1+
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
decreased CD4-positive, alpha-beta T cell number |
J:120100
|
Runx1tm6Spe/Runx1tm6Spe
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
embryonic lethality during organogenesis, complete penetrance |
J:120100
|
|
hemopericardium |
J:120100
|
|
hemoperitoneum |
J:120100
|
|
intraventricular hemorrhage |
J:120100
|
Runx1tm7Spe/Runx1+
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
decreased CD4-positive, alpha-beta T cell number |
J:120100
|
Runx1tm7Spe/Runx1tm7Spe
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
embryonic lethality during organogenesis, complete penetrance |
J:120100
|
|
hemopericardium |
J:120100
|
|
hemoperitoneum |
J:120100
|
|
intraventricular hemorrhage |
J:120100
|
Runx1tm8Spe/Runx1+
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
decreased CD4-positive, alpha-beta T cell number |
J:120100
|
Runx1tm8Spe/Runx1tm8Spe
involves: 129/Sv * C57BL/6
|
abnormal embryonic hematopoiesis |
J:120100
|
|
lung inflammation |
J:120100
|
|
postnatal growth retardation |
J:120100
|
|
postnatal lethality, complete penetrance |
J:120100
|
Slc17a8tm1(cre)Lowl/Slc17a8+
Runx1tm3Spe/Runx1tm3Spe
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6NCr
|
abnormal sensory neuron innervation pattern |
J:193903
|
|
abnormal sympathetic neuron physiology |
J:193903
|
|
decreased sensory neuron number |
J:193903
|
Excel File
Analysis Tools