Ankmy2tm1b(EUCOMM)Hmgu/Ankmy2tm1b(EUCOMM)Hmgu
Gli2tm1Alj/Gli2tm1Alj
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N
|
abnormal embryonic neuroepithelial layer differentiation |
J:297055
|
|
embryonic lethality prior to organogenesis |
J:297055
|
|
exencephaly |
J:297055
|
|
incomplete rostral neuropore closure |
J:297055
|
Cdk20tm1.1Jegg/Cdk20tm1.1Jegg
Gli2tm1Alj/Gli2tm1Alj
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * FVB/N
|
abnormal dorsal-ventral axis patterning |
J:243907
|
|
abnormal neural tube morphology |
J:243907
|
En1tm2(cre)Gld/En1+
Gli1tm2Alj/Gli1tm2Alj
Gli2tm1Alj/Gli2tm6Alj
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
|
abnormal cerebellar foliation |
J:108507
|
|
abnormal cerebellum development |
J:108507
|
|
abnormal cerebellum morphology |
J:108507
|
Gli1tm1Alj/Gli1+
Gli2tm1Alj/Gli2tm1Alj
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal lung morphology |
J:60986
|
|
small lung |
J:60986
|
Gli1tm1Alj/Gli1tm1Alj
Gli2tm1Alj/Gli2+
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal digestive system morphology |
J:60986
|
|
abnormal external male genitalia morphology |
J:60986
|
|
abnormal floor plate morphology |
J:60986
|
|
abnormal gait |
J:60986
|
|
abnormal left lung morphology |
J:60986
|
|
abnormal lung morphology |
J:60986
|
|
abnormal motor neuron morphology |
J:60986
|
|
abnormal notochord morphology |
J:60986
|
|
abnormal right lung accessory lobe morphology |
J:60986
|
|
abnormal right lung cranial lobe morphology |
J:60986
|
|
cryptorchism |
J:60986
|
|
decreased body size |
J:60986
|
|
impaired righting response |
J:60986
|
|
neonatal lethality, incomplete penetrance |
J:60986
|
|
small lung |
J:60986
|
Gli1tm1Alj/Gli1tm1Alj
Gli2tm1Alj/Gli2tm1Alj
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal digit morphology |
J:60986
|
|
abnormal lung morphology |
J:60986
|
|
abnormal motor neuron morphology |
J:60986
|
|
abnormal telencephalon morphology |
J:60986
|
|
absent pituitary gland |
J:60986
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:60986
|
|
perinatal lethality, complete penetrance |
J:60986
|
|
small lung |
J:60986
|
Gli1tm2Alj/Gli1+
Gli2tm1Alj/Gli2tm1Alj
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * Swiss Webster
|
small lung |
J:79392
|
Gli1tm2Alj/Gli1+
Gli2tm1Alj/Gli2tm1Alj
Gli3Xt/Gli3Xt
involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster
|
abnormal motor neuron morphology |
J:87948
|
|
abnormal neuron differentiation |
J:87948
|
|
abnormal neuronal precursor cell number |
J:87948
|
|
abnormal neuronal precursor proliferation |
J:87948
|
|
abnormal spinal cord morphology |
J:87948
|
|
abnormal ventral interneuron 3 morphology |
J:87948
|
|
abnormal ventral interneuron morphology |
J:87948
|
|
absent floor plate |
J:87948
|
|
decreased motor neuron number |
J:87948
|
Gli1tm2Alj/Gli1tm2Alj
Gli2tm1Alj/Gli2+
involves: 129 * Black Swiss * Swiss Webster
|
abnormal floor plate morphology |
J:79392
|
|
persistence of notochord tissue |
J:79392
|
|
small lung |
J:79392
|
Gli1tm2Alj/Gli1tm2Alj
Gli2tm1Alj/Gli2tm1Alj
involves: 129/Sv * Black Swiss * Swiss Webster
|
impaired lung lobe morphogenesis |
J:79392
|
|
polydactyly |
J:79392
|
|
small lung |
J:79392
|
Gli1tm2Alj/Gli1tm2Alj
Gli2tm3.1(Gli1)Alj/Gli2tm3.1(Gli1)Alj
involves: 129/Sv * Black Swiss * Swiss Webster
|
normal
nervous system phenotype |
J:79392
|
Gli1tm2Alj/Gli1tm2Alj
Gli2tm5.1(GLI3)Alj/Gli2tm5.1(GLI3)Alj
involves: 129S6/SvEvTac * Swiss Webster
|
abnormal ventral interneuron 3 morphology |
J:87948
|
|
absent floor plate |
J:87948
|
Gli2tm1(cre/ERT2)Tipe/Gli2+
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+
involves: 129X1/SvJ
|
abnormal bronchioalveolar stem cell morphology |
J:264185
|
|
abnormal pulmonary alveolus morphology |
J:264185
|
|
decreased type II pneumocyte number |
J:264185
|
|
emphysema |
J:264185
|
|
overexpanded pulmonary alveolus |
J:264185
|
Gli2tm1Alj/Gli2+
Gli3Xt/Gli3Xt
involves: 101/H * 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster
|
increased neuronal precursor cell number |
J:87948
|
Gli2tm1Alj/Gli2+
Gli3Xt-J/Gli3+
involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1
|
polydactyly |
J:38381
|
Gli2tm1Alj/Gli2+
Gli3Xt-J/Gli3Xt-J
involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1
|
abnormal skeleton morphology |
J:38381
|
|
fusion of vertebral arches |
J:38381
|
|
polyphalangy |
J:38381
|
Gli2tm1Alj/Gli2+
Kif7tm1.2Hui/Kif7tm1.2Hui
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * CD-1
|
abnormal neural tube morphology |
J:152259
|
Gli2tm1Alj/Gli2tm1Alj
Gli3Xt-J/Gli3+
involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1
|
abnormal cartilage development |
J:38381
|
|
abnormal digit morphology |
J:38381
|
|
abnormal long bone morphology |
J:38381
|
|
abnormal skeleton morphology |
J:38381
|
|
abnormal vertebrae development |
J:38381
|
|
mandible hypoplasia |
J:38381
|
|
polydactyly |
J:38381
|
|
short femur |
J:38381
|
|
short fibula |
J:38381
|
|
short humerus |
J:38381
|
|
short radius |
J:38381
|
|
short tibia |
J:38381
|
|
short ulna |
J:38381
|
|
split sternum |
J:38381
|
Gli2tm1Alj/Gli2tm1Alj
Gli3Xt-J/Gli3Xt-J
involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1
|
embryonic lethality, complete penetrance |
J:38381
|
Gli2tm1Alj/Gli2tm1Alj
Gli3Xt-J/Gli3Xt-J
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * Swiss Webster
|
abnormal ventral interneuron 0 morphology |
J:92067
|
|
abnormal ventral interneuron 1 morphology |
J:92067
|
|
abnormal ventral interneuron 2 morphology |
J:92067
|
|
abnormal ventral interneuron 3 morphology |
J:92067
|
|
abnormal ventral interneuron morphology |
J:92067
|
|
decreased motor neuron number |
J:92067
|
Gli2tm1Alj/Gli2tm1Alj
Gli3Xt/Gli3+
involves: 101/H * 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster
|
increased neuronal precursor cell number |
J:87948
|
Gli2tm1Alj/Gli2tm1Alj
Gli3Xt/Gli3+
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal lung bud morphology |
J:49603
|
|
abnormal lung development |
J:49603
|
|
abnormal lung morphology |
J:49603
|
|
abnormal tracheal cartilage morphology |
J:49603
|
|
esophageal atresia |
J:49603
|
|
pulmonary hypoplasia |
J:49603
|
|
trachea stenosis |
J:49603
|
|
tracheoesophageal fistula |
J:49603
|
Gli2tm1Alj/Gli2tm1Alj
Gli3Xt/Gli3Xt
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal endoderm development |
J:49603
|
|
abnormal esophagus development |
J:49603
|
|
abnormal foregut morphology |
J:49603
|
|
abnormal lung development |
J:49603
|
|
abnormal trachea development |
J:49603
|
|
absent esophagus |
J:49603
|
|
absent lungs |
J:49603
|
|
absent trachea |
J:49603
|
|
embryonic lethality during organogenesis, incomplete penetrance |
J:49603
|
Gli2tm1Alj/Gli2tm1Alj
Ift122sopb/Ift122sopb
involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J
|
abnormal neural tube morphology |
J:168317
|
Gli2tm1Alj/Gli2tm1Alj
Kif7maki/Kif7maki
Tg(Hlxb9-GFP)1Tmj/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
|
abnormal neural tube morphology |
J:151965
|
|
absent floor plate |
J:151965
|
Gli2tm1Alj/Gli2tm1Alj
Pax6Sey/Pax6Sey
involves: 129S1/Sv * 129X1/SvJ
|
abnormal neuron differentiation |
J:112802
|
Gli2tm1Alj/Gli2tm1Alj
Ptch1tm1Mps/Ptch1tm1Mps
involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
|
abnormal brain development |
J:79392
|
|
abnormal spinal cord morphology |
J:79392
|
|
abnormal ventral interneuron 3 morphology |
J:79392
|
|
embryonic lethality during organogenesis, complete penetrance |
J:79392
|
|
exencephaly |
J:79392
|
|
increased motor neuron number |
J:79392
|
|
normal
nervous system phenotype |
J:79392
|
Gli2tm1Blnw/Gli2tm1Blnw
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal maxillary dental arch morphology |
J:145182
|
|
abnormal maxillary frontal process morphology |
J:145182
|
|
abnormal neural tube closure |
J:145182
|
|
abnormal neural tube morphology |
J:145182
|
|
exencephaly |
J:145182
|
|
polydactyly |
J:145182
|
|
prenatal lethality, complete penetrance |
J:145182
|
Gli2tm1Blnw/Gli2tm1Blnw
Shhtm1Chg/Shhtm1Chg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
normal
cellular phenotype |
J:145182
|
|
normal
nervous system phenotype |
J:145182
|
Gli2tm2.1Alj/Gli2+
Gli3Xt-J/Gli3Xt-J
involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster
|
abnormal mammary gland bud morphology |
J:112460
|
Gli2tm2.1Alj/Gli2+
Shhtm1Chg/Shhtm1Chg
either: (involves: 129) or (involves: 129 * Black Swiss)
|
abnormal spinal cord morphology |
J:73074
|
|
abnormal telencephalon development |
J:73074
|
|
decreased embryo size |
J:73074
|
Gli2tm2.1Alj/Gli2tm2.1Alj
Gli3Xt-J/Gli3+
involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster
|
normal
reproductive system phenotype |
J:112460
|
Gli2tm2.1Alj/Gli2tm2.1Alj
Gli3Xt-J/Gli3Xt-J
involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster
|
embryonic lethality during organogenesis, complete penetrance |
J:112460
|
Gli2tm2.1Alj/Gli2tm2.1Alj
Shhtm1Chg/Shhtm1Chg
either: (involves: 129) or (involves: 129 * Black Swiss)
|
abnormal spinal cord interneuron morphology |
J:73074
|
|
absent floor plate |
J:73074
|
|
cyclopia |
J:73074
|
|
decreased motor neuron number |
J:73074
|
Gli2tm2.1Alj/Gli2tm2.1Alj
Tmem107schlei/Tmem107schlei
involves: 129S6/SvEvTac * C3HeB/FeJ * C57BL/6J
|
abnormal floor plate morphology |
J:186552
|
Gli2tm2.1Alj/Gli2tm3(Gli1)Alj
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)
|
no abnormal phenotype detected |
J:73074
|
Gli2tm2.1Alj/Gli2tm3.1(Gli1)Alj
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)
|
normal
nervous system phenotype |
J:73074
|
|
progressive hair loss |
J:73074
|
|
normal
respiratory system phenotype |
J:73074
|
Gli2tm2.1Alj/Gli2tm3.1(Gli1)Alj
Shhtm1Chg/Shhtm1Chg
either: (involves: 129) or (involves: 129 * Black Swiss)
|
abnormal diencephalon morphology |
J:73074
|
|
abnormal ventral interneuron 3 morphology |
J:73074
|
|
absent floor plate |
J:73074
|
|
decreased motor neuron number |
J:73074
|
|
megacephaly |
J:73074
|
Gli2tm3(Gli1)Alj/Gli2tm3(Gli1)Alj
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)
|
bradykinesia |
J:73074
|
|
decreased body size |
J:73074
|
|
impaired limb coordination |
J:73074
|
|
postnatal lethality, incomplete penetrance |
J:73074
|
|
premature death |
J:73074
|
|
progressive hair loss |
J:73074
|
Gli2tm3(Gli1)Alj/Gli2tm3(Gli1)Alj
involves: 129S6/SvEvTac * Black Swiss * Swiss Webster
|
normal
reproductive system phenotype |
J:112460
|
Gli2tm3(Gli1)Alj/Gli2tm3(Gli1)Alj
Gli3Xt-J/Gli3+
involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster
|
abnormal mammary gland bud morphology |
J:112460
|
Gli2tm3.1(Gli1)Alj/Gli2+
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)
|
progressive hair loss |
J:73074
|
Gli2tm3.1(Gli1)Alj/Gli2+
Gli3Xt-J/Gli3+
either: (involves: 129S6/SvEvTac * C3H/HeJ) or (involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ)
|
male infertility |
J:73074
|
|
polydactyly |
J:73074
|
|
premature death |
J:73074
|
|
progressive hair loss |
J:73074
|
Gli2tm3.1(Gli1)Alj/Gli2tm3.1(Gli1)Alj
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)
|
normal
nervous system phenotype |
J:73074
|
|
preweaning lethality, complete penetrance |
J:73074
|
Gli2tm3.1Blnw/Gli2tm3.1Blnw
Ptch1tm1Mps/?
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H * C57BL/6
|
abnormal neural tube morphology |
J:186503
|
Gli2tm4.1(Gli2)Alj/Gli2tm4.1(Gli2)Alj
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)
|
no abnormal phenotype detected |
J:73074
|
Gli2tm5(GLI3)Alj/Gli2tm1Alj
involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
|
abnormal neural tube morphology |
J:87948
|
|
absent floor plate |
J:87948
|
Gli2tm5(GLI3)Alj/Gli2tm5(GLI3)Alj
involves: Swiss Webster
|
abnormal floor plate morphology |
J:87948
|
|
abnormal neuron specification |
J:87948
|
|
abnormal ventral interneuron 3 morphology |
J:87948
|
Gli2tm5.1(GLI3)Alj/Gli2tm5.1(GLI3)Alj
involves: Swiss Webster
|
abnormal neuron specification |
J:87948
|
|
postnatal lethality, complete penetrance |
J:87948
|
Gli2tm5.1(GLI3)Alj/Gli2tm5.1(GLI3)Alj
Gli3Xt/Gli3Xt
involves: 101/H * C3H/HeH * C57BL * CBA/H * Swiss Webster
|
abnormal ventral interneuron 3 morphology |
J:87948
|
|
absent floor plate |
J:87948
|
|
normal
limbs/digits/tail phenotype |
J:87948
|
Gli3Xt-J/Gli3Xt-J
Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+
Ihhtm1Amc/Ihhtm1Amc
Tg(Col2a1-cre)3Amc/0
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ
|
abnormal long bone diaphysis morphology |
J:154905
|
|
decreased body size |
J:154905
|
|
perinatal lethality, complete penetrance |
J:154905
|
|
short limbs |
J:154905
|
|
normal
skeleton phenotype |
J:154905
|
Gt(ROSA)26Sortm1(Gli2)Jmao/Gt(ROSA)26Sor+
Smotm2Amc/Smotm2Amc
Nkx3-2tm1(cre)Wez/Nkx3-2+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
|
normal
digestive/alimentary phenotype |
J:199664
|
Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+
Ihhtm1Amc/Ihhtm1Amc
involves: 129S1/Sv * 129X1/SvJ
|
abnormal long bone epiphyseal plate proliferative zone |
J:154905
|
|
abnormal long bone hypertrophic chondrocyte zone |
J:154905
|
|
abnormal osteoblast differentiation |
J:154905
|
|
disorganized long bone epiphyseal plate |
J:154905
|
Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+
Ihhtm1Amc/Ihhtm1Amc
Tg(Col2a1-cre)3Amc/0
involves: 129S1/Sv * 129X1/SvJ
|
abnormal long bone epiphyseal plate proliferative zone |
J:154905
|
|
abnormal long bone hypertrophic chondrocyte zone |
J:154905
|
|
abnormal osteoblast differentiation |
J:154905
|
|
abnormal perichondrium morphology |
J:154905
|
|
disorganized long bone epiphyseal plate |
J:154905
|
|
perinatal lethality, complete penetrance |
J:154905
|
|
normal
skeleton phenotype |
J:154905
|
Excel File
Analysis Tools