Kif7^maki
Chemically induced Allele Detail

Summary

• Symbol: Kif7^maki
• Name: kinesin family member 7; matariki
• MGI ID: MGI:4355980
• Gene: Kif7 Location: Chr7:79347846-79365468 bp, - strand Genetic Position: Chr7, 45.09 cM, cytoband D2
• Alliance: Kif7^maki page

Diaphragmatic hernia in Kif7^maki/Kif7^maki mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced a T-to-C missense mutation (c.389T>C) resulting in an p.L130P mutation in the conserved region of the motor domain of the encoded protein. (J:151965)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif7 Mutation: 39 strains or lines available

References

• Original: J:151965 Liem KF Jr, et al., Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13377-82
• All: 3 reference(s)