51 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh Nrastm1.1Nesh/Nrastm1.1Nesh Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(Tyr-cre/ERT2)13Bos/0 B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh Stk11tm1.1Rdp	increased cutaneous melanoma incidence	J:220627
	increased metastatic potential	J:220627
Krastm4Tyj/Kras+ Stk11tm1.1Rdp/Stk11tm1.1Rdp involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N	increased lung adenocarcinoma incidence	J:124682
	increased lung large cell carcinoma incidence	J:124682
	increased lung squamous cell carcinoma incidence	J:124682
	increased lung tumor incidence	J:124682
	increased metastatic potential	J:124682
	premature death	J:124682
Krastm4Tyj/Kras+ Stk11tm1.1Rdp/Stk11tm1.2Rdp involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N	increased lung adenocarcinoma incidence	J:124682
	increased lung large cell carcinoma incidence	J:124682
	increased lung squamous cell carcinoma incidence	J:124682
	increased lung tumor incidence	J:124682
	increased metastatic potential	J:124682
	premature death	J:124682
Krastm4Tyj/Kras+ Stk11tm1.2Rdp/Stk11tm1.2Rdp involves: 129S4/SvJae * 129S6/SvEvTac	increased macrophage cell number	J:197037
Krastm4Tyj/Kras+ Stk11tm1.1Gne/Stk11tm1.1Gne involves: 129S4/SvJae * C57BL/6N	pancreas cyst	J:195229
Pdx1tm1Egs/Pdx1+ Stk11tm1.1Gne/Stk11tm1.1Gne involves: 129S1/Sv * C57BL/6N	increased cell proliferation	J:195229
	pancreas cyst	J:195229
Ptentm2Mak/Ptentm2Mak Stk11tm1Keis/Stk11tm1Keis Tg(Cyp1a1-cre/ERT)1Dwi/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA	abnormal urinary bladder mucosa morphology	J:169565
	abnormal urinary bladder urothelium morphology	J:169565
	enlarged urinary bladder	J:169565
	increased urinary bladder carcinoma incidence	J:169565
	premature death	J:169565
	urinary bladder obstruction	J:169565
Ptgs2tm1Jed/Ptgs2+ Stk11tm1Tpm/Stk11+ involves: 129S7/SvEvBrd * C57BL/6 * CD-1	gastric polyps	J:93361
	intestine polyps	J:93361
Ptgs2tm1Jed/Ptgs2tm1Jed Stk11tm1Tpm/Stk11+ involves: 129S7/SvEvBrd * C57BL/6 * CD-1	decreased tumor incidence	J:93361
	gastric polyps	J:93361
	intestine polyps	J:93361
Stk11tm1.1Mlfr/Stk11+ Trp53tm1Tyj/Trp53+ involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	distended abdomen	J:104347
	gastric polyps	J:104347
	increased hamartoma incidence	J:104347
	increased lymphoma incidence	J:104347
	increased osteosarcoma incidence	J:104347
	increased sarcoma incidence	J:104347
	premature death	J:104347
Stk11tm1.1Mlfr/Stk11+ Trp53tm1Tyj/Trp53tm1Tyj involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	colon polyps	J:104347
	increased hamartoma incidence	J:104347
	premature death	J:104347
Stk11tm1Mmt/Stk11+ Trp53tm1Brd/Trp53+ involves: 129S7/SvEvBrd * 129X1/SvJ	increased hamartoma incidence	J:107275
Stk11tm1Mmt/Stk11+ Trp53tm1Brd/Trp53tm1Brd involves: 129S7/SvEvBrd * 129X1/SvJ	abnormal hepatocyte morphology	J:107275
	increased hamartoma incidence	J:107275
	increased hepatocellular carcinoma incidence	J:107275
	increased liver tumor incidence	J:107275
	increased ovary tumor incidence	J:107275
	increased tumor incidence	J:107275
	premature death	J:107275
Stk11tm1Rdp/Stk11tm1Rdp Tg(MMTV-Erbb2*,-cre)1Mul/0 involves: 129S6/SvEvTac * C57BL/6	abnormal mammary gland morphology	J:198481
	decreased tumor latency	J:198481
	increased mammary gland tumor incidence	J:198481
Stk11tm2.1Tpm/Stk11tm2.1Tpm involves: BALB/c * C57BL/6	abnormal dorsal aorta morphology	J:70892
	abnormal head mesenchyme morphology	J:70892
	abnormal neural fold formation	J:70892
	abnormal neural tube closure	J:70892
	abnormal notochord morphology	J:70892
	abnormal placental labyrinth vasculature morphology	J:70892
	abnormal somite development	J:70892
	abnormal spongiotrophoblast layer morphology	J:70892
	abnormal vascular smooth muscle morphology	J:70892
	abnormal visceral yolk sac morphology	J:70892
	abnormal vitelline vasculature morphology	J:70892
	absent first pharyngeal arch	J:70892
	absent vitelline blood vessels	J:70892
	delayed chorioallantoic fusion	J:70892
	embryonic lethality during organogenesis, complete penetrance	J:70892
	failure of initiation of embryo turning	J:70892
	first pharyngeal arch hypoplasia	J:70892
	placenta hemorrhage	J:70892
	small placenta	J:70892