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Gstp2
Gene Detail
 Symbol
Name
ID
Gstp2
glutathione S-transferase, pi 2
MGI:95864
Synonyms Gst3, Gst-3, Gst p-2, GSTpiA
Feature Type protein coding gene
Genetic Map
Chromosome 19
3.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr19:4040351-4042165 bp, - strand
From Ensembl annotation of GRCm38

  1815 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:660  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 2 dog; 2 zebrafish

Gene Tree: Gstp2

Human
homologs
Human Homolog GSTP1, glutathione S-transferase pi 1
NCBI Gene ID 2950
neXtProt AC  NX_P09211
Human Synonyms  DFN7, FAEES3, GST3, GSTP, HEL-S-22, PI
Human Chr (Location)  11q13; chr11:67583595-67586653 (+)  GRCh38
Alleles
and
phenotypes
All alleles(15) : Targeted(2) Gene trapped(13)
 
Mutant mice with null mutations in both Gstp1 and Gstp2 exhibit an increased susceptibility to DMBA and TPA induced skin papillomas. Male mutant mice exhibit an increased body weight with age.
 
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process glutathione metabolic process, metabolic process
Component cytoplasm, cytosol, ...
Function dinitrosyl-iron complex binding, drug binding, ...
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (95)    Tissues (95)    Images (13)
Theiler Stages: 22, 28
Assay TypeResults
Immunohistochemistry 1
RNA in situ 94
cDNA source data(15)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(22) Genomic(6) cDNA(15) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000038155 (Evidence)
Entrez Gene14869 (Evidence)
UniGene441542
DoTSDT.102559019, DT.94162746
EC2.5.1.18
Consensus CDS ProjectCCDS29412.1
International Mouse Knockout Project StatusGstp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038155 Ensembl Gene Model | MGI Sequence Detail 1815 C57BL/6J ±  kb
transcript ENSMUST00000042700 Ensembl | MGI Sequence Detail 633 Not Applicable 
polypeptide ENSMUSP00000038931 Ensembl | MGI Sequence Detail 210 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(82 from dbSNP Build 137)    SNPs within 2kb including multiple locations(126)
Protein-related
information
ResourceIDDescription
InterPro IPR004046 Glutathione S-transferase, C-terminal
InterPro IPR010987 Glutathione S-transferase, C-terminal-like
InterPro IPR004045 Glutathione S-transferase, N-terminal
InterPro IPR003082 Glutathione S-transferase, Pi class
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000008393 glutathione S-transferase P 2
References (Earliest) J:10161 Board PG, et al., Isolation of a cDNA clone and localization of the human glutathione S-transferase 3 genes to chromosome bands 11q13 and 12q13-14. Ann Hum Genet. 1989 Jul;53(Pt 3):205-13
(Latest) J:191045 Huebner AJ, et al., Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46
All references(60)
Other
accession IDs
MGD-MRK-10306, MGD-MRK-10311, MGD-MRK-10323

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory