About   Help   FAQ
Gstp2
Gene Detail
 Symbol
Name
ID
Gstp2
glutathione S-transferase, pi 2
MGI:95864
Synonyms Gst3, Gst-3, Gst p-2, GSTpiA
Feature Type protein coding gene
Genetic Map
Chromosome 19
3.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr19:4040285-4042236 bp, - strand
From VEGA annotation of GRCm38

  1952 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:660  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 2 dog; 3 western clawed frog; 2 zebrafish

Gene Tree: Gstp2

Human
homologs
Human Homolog GSTP1, glutathione S-transferase pi 1
NCBI Gene ID 2950
neXtProt AC  NX_P09211
Human Synonyms  DFN7, FAEES3, GST3, GSTP, HEL-S-22, PI
Human Chr (Location)  11q13; chr11:67583595-67586653 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(13) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mutant mice with null mutations in both Gstp1 and Gstp2 exhibit an increased susceptibility to DMBA and TPA induced skin papillomas. Male mutant mice exhibit an increased body weight with age.
 
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process glutathione metabolic process, metabolic process
Component cytoplasm, cytosol, ...
Function dinitrosyl-iron complex binding, drug binding, ...
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (95)    Tissues (95)    Images (13)
Theiler Stages: 22, 28
Assay TypeResults
Immunohistochemistry 1
RNA in situ 94
cDNA source data(15)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(22) Genomic(6) cDNA(15) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000046063 (Evidence)
Ensembl Gene ModelENSMUSG00000038155 (Evidence)
Entrez Gene14869 (Evidence)
UniGene441542
DoTSDT.102559019, DT.94162746
EC2.5.1.18
Consensus CDS ProjectCCDS29412.1
International Mouse Knockout Project StatusGstp2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000046063 VEGA Gene Model | MGI Sequence Detail 1952 C57BL/6J ±  kb
transcript OTTMUST00000120280 VEGA | MGI Sequence Detail 770 Not Applicable 
polypeptide OTTMUSP00000066650 VEGA | MGI Sequence Detail 210 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(84 from dbSNP Build 137)    SNPs within 2kb including multiple locations(128)
Protein-related
information
ResourceIDDescription
InterPro IPR004046 Glutathione S-transferase, C-terminal
InterPro IPR010987 Glutathione S-transferase, C-terminal-like
InterPro IPR004045 Glutathione S-transferase, N-terminal
InterPro IPR003082 Glutathione S-transferase, Pi class
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000008393 glutathione S-transferase P 2
References (Earliest) J:10161 Board PG, et al., Isolation of a cDNA clone and localization of the human glutathione S-transferase 3 genes to chromosome bands 11q13 and 12q13-14. Ann Hum Genet. 1989 Jul;53(Pt 3):205-13
(Latest) J:191045 Huebner AJ, et al., Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46
All references(61)
Other
accession IDs
MGD-MRK-10306, MGD-MRK-10311, MGD-MRK-10323

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/26/2014
MGI 5.19
The Jackson Laboratory