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Ar
Gene Detail
Symbol

Name
ID
Ar
androgen receptor
MGI:88064
Feature Type
protein coding gene
Genetic Map
Chromosome X
42.82 cM
Detailed Genetic Map ± 1 cM


Mapping data(33)
Sequence Map
ChrX:98149721-98323215 bp, + strand
From VEGA annotation of GRCm38

  173495 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:28  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: androgen receptor
Gene Tree: Ar

Human
homologs
Human Homolog AR, androgen receptor
NCBI Gene ID 367
neXtProt AC  NX_P10275
Human Synonyms  AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Human Chr (Location)  Xq12; chrX:67544032-67730619 (+)  GRCh38
Disease Associations  (5) Diseases Associated with Human AR
Mutations,
alleles, and
phenotypes
All mutations/alleles(24) : Endonuclease-mediated(1) Spontaneous(3) Targeted(20)
Incidental mutations (data from Mutagenetix , APF )
 
Hemizygous mutant males are androgen-resistant and therefore have small, undescended testes, and lack epididymal structures, vas deferens, and male accessory glands. They resemble females physically and behaviorally, but lack female reproductive organs.
 
Human Diseases Modeled Using Mouse Ar (5)    Alleles Annotated to Human Diseases(9)    Phenotype Images(4)
Interactions
Ar interacts with 505 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (50 records)
Data Summary: Results (185)    Tissues (150)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 16
RNA in situ 148
RT-PCR 21
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(51) Genomic(14) cDNA(26) Primer pair(7) Other(4)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000018072 (Evidence)
Ensembl Gene ModelENSMUSG00000046532 (Evidence)
Entrez Gene11835 (Evidence)
DFCITC1588979, TC1605269, TC1611475
DoTSDT.101716332, DT.111022595, DT.482461
NIA Mouse Gene IndexU020040
PDB2QPY
Consensus CDS ProjectCCDS30294.1
International Mouse Knockout Project StatusAr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018072 VEGA Gene Model | MGI Sequence Detail 173495 C57BL/6J ±  kb
transcript OTTMUST00000043610 VEGA | MGI Sequence Detail 9096 Not Applicable 
polypeptide OTTMUSP00000019597 VEGA | MGI Sequence Detail 899 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(1)
Polymorphisms
All PCR and RFLP(7) : PCR(2) RFLP(5) SNPs within 2kb(495 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001103 Androgen receptor
InterPro IPR008946 Nuclear hormone receptor, ligand-binding
InterPro IPR000536 Nuclear hormone receptor, ligand-binding, core
InterPro IPR013088 Zinc finger, NHR/GATA-type
InterPro IPR001628 Zinc finger, nuclear hormone receptor-type
Protein Ontology PR:000004191 androgen receptor
References
(Earliest) J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
(Latest) J:213061 De Gendt K, et al., Genome-wide identification of AR-regulated genes translated in Sertoli cells in vivo using the RiboTag approach. Mol Endocrinol. 2014 Apr;28(4):575-91
All references(380)
Disease annotation references (11)
Other
accession IDs
MGD-MRK-1384, MGD-MRK-15046, MGI:2148007

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory