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Rgs13
Gene Detail
Symbol

Name
ID
Rgs13
regulator of G-protein signaling 13
MGI:2180585
Feature Type
protein coding gene
Genetic Map
Chromosome 1
62.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:144138654-144177372 bp, - strand
From VEGA annotation of GRCm38

  38719 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14774  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: RGS13
Protein SuperFamily: regulator of G protein signaling, RGS4 type
Gene Tree: Rgs13

Human
homologs
RGS13, regulator of G-protein signaling 13
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 6003
neXtProt AC: NX_O14921

Human Chr (Location): 1q31.2; chr1:192636138-192660311 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from APF )
 
Mice homozygous for a null allele exhibit increased mast cell degranulation and increased anaphylaxis.
 
Phenotype Images(2)
Interactions
Rgs13 interacts with 137 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (32)    Tissues (25)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 9
Northern blot 20
RT-PCR 1
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) Genomic(1) cDNA(8) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000020880 (Evidence)
Ensembl Gene Model ENSMUSG00000051079 (Evidence)
Entrez Gene 246709 (Evidence)
UniGene 38271
DFCI TC1591160, TC1637268
DoTS DT.101347442, DT.99847311
NIA Mouse Gene Index U021857
Consensus CDS Project CCDS15348.1
International Mouse Phenotyping Consortium Status Rgs13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020880 VEGA Gene Model | MGI Sequence Detail 38719 C57BL/6J ±  kb
transcript OTTMUST00000049361 VEGA | MGI Sequence Detail 1510 Not Applicable 
polypeptide OTTMUSP00000022853 VEGA | MGI Sequence Detail 158 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(4) UniProt(1)
Polymorphisms
PCR(1) : SNPs within 2kb(262 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024066 Regulator of G-protein signaling, domain 1
InterPro IPR016137 Regulator of G protein signalling superfamily
Protein Ontology PR:000013948 regulator of G-protein signaling 13
References
(Earliest) J:74612 Sierra DA, et al., Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics. 2002 Feb;79(2):177-85
(Latest) J:199530 Hwang IY, et al., Rgs13 constrains early B cell responses and limits germinal center sizes. PLoS One. 2013;8(3):e60139
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory