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Fryl Gene Detail
Summary
  • Symbol
    Fryl
  • Name
    FRY like transcription coactivator
  • Synonyms
    2310004H21Rik, 2510002A14Rik, 9030227G01Rik, mKIAA0826
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919563
    NCBI Gene: 72313
Location & Maps
more
  • Sequence Map
    Chr5:73019987-73256619 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      236633 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 38.44 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FRYL, FRY like transcription coactivator
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FRYL, FRY like transcription coactivator
    Orthology source: HomoloGene
  • Synonyms
    AF4p12, KIAA0826, MOR2
  • Links
    NCBI Gene ID: 285527
    neXtProt AC: NX_O94915

  • Chr Location
    4p11; chr4:48497363-48780312 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 103956
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: FRYL
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    238 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    378
  • Chemically induced (other)
    2
  • Gene trapped
    369
  • Radiation induced
    1
  • Spontaneous
    3
  • Targeted
    3
  • Genomic Mutations
    6 involving Fryl
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024870 VEGA Gene Model | MGI Sequence Detail 236633 C57BL/6J ±  kb
transcript OTTMUST00000061269 VEGA | MGI Sequence Detail 11340 Not Applicable  
polypeptide OTTMUSP00000030013 VEGA | MGI Sequence Detail 3007 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1894 from dbSNP Build 142
Protein
Information
less
  • UniProt
    21 Sequences
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR029473 Cell morphogenesis central region
    IPR025481 Cell morphogenesis protein C-terminal
    IPR025614 Cell morphogenesis protein N-terminal
Molecular
Reagents
less
  • All nucleic 142
    cDNA 142

    Microarray probesets 8
Other
Accession IDs
less
MGI:1914271, MGI:1922825, MGI:2141007, MGI:2443838
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 2
    Phenotypes 238
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory