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Fryl
Gene Detail
Symbol

Name
ID
Fryl
furry homolog-like (Drosophila)
MGI:1919563
Synonyms
2310004H21Rik, 2510002A14Rik, 9030227G01Rik, mKIAA0826
Feature Type
protein coding gene
Genetic Map
Chromosome 5
38.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:73020322-73256618 bp, - strand
From VEGA annotation of GRCm38

  236297 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:103956  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FRYL
Gene Tree: Fryl

Human
homologs
FRYL, FRY-like
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 285527
neXtProt AC: NX_O94915

Human Synonyms: AF4p12, KIAA0826

Human Chr (Location): 4p11; chr4:48497363-48780312 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(399) : Gene trapped(396) Radiation induced(1) Targeted(2)
Genomic Mutations involving Fryl (1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(4)
Interactions
Fryl interacts with 409 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process actin filament reorganization, cell morphogenesis, ...
Component cell cortex, site of polarized growth
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (40)    Tissues (11)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 40
cDNA source data(141)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase fryl ; ZFIN fryl    NEW 
Molecular
reagents
All nucleic(142) cDNA(142)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000024870 (Evidence)
Ensembl Gene Model ENSMUSG00000070733 (Evidence)
Entrez Gene 72313 (Evidence)
UniGene 260594
DFCI TC1577746, TC1612797, TC1589574, TC1637415, TC1662404, TC1631786, TC1625617, TC1661330, TC1645017, TC1660671, TC1650945
DoTS DT.101181920, DT.103570089, DT.101281505, DT.492599, DT.101355275, DT.91330409, DT.55137275, DT.55176999, DT.99839588, DT.101198841, DT.101273824
NIA Mouse Gene Index U360017, U043847
Consensus CDS Project CCDS19337.2, CCDS19338.1
International Mouse Phenotyping Consortium Status Fryl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024870 VEGA Gene Model | MGI Sequence Detail 236297 C57BL/6J ±  kb
transcript OTTMUST00000061269 VEGA | MGI Sequence Detail 11339 Not Applicable 
polypeptide OTTMUSP00000030013 VEGA | MGI Sequence Detail 3007 Not Applicable 

For the selected sequences
All sequences(142) RefSeq(35) UniProt(11)
Polymorphisms
SNPs within 2kb(1938 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1970)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
InterPro IPR025481 Cell morphogenesis protein C-terminal
InterPro IPR025614 Cell morphogenesis protein N-terminal
Protein Ontology PR:000007673 protein furry-like
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39
All references(42)
Other
accession IDs
MGI:1914271, MGI:1922825, MGI:2141007, MGI:2443838

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory