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Human Disease and Mouse Model Detail
Human Disease Lung Cancer
OMIM ID: 211980
Synonyms Lung Cancer
View all models View ALL (28) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Kras* KRAS* View 13 models 1:1 Homology
     Cdkn2a* CDKN2A View 1 model 1:1 Homology
Ctnnb1* CTNNB1 View 1 model 1:1 Homology
Fgfr3* FGFR3 View 1 model 1:1 Homology
Foxm1* FOXM1 View 1 model 1:1 Homology
Robo1* ROBO1 View 1 model 1:1 Homology
Tgfbr2* TGFBR2 View 1 model 1:1 Homology
Trp53* TP53 View 4 models 1:1 Homology
Xpc* XPC View 2 models 1:1 Homology
     Braf BRAF*   1:1 Homology
Casp8 CASP8*   1:1 Homology
Cyp2a4, Cyp2a5 CYP2A6*, CYP2A7, CYP2A13   2:3 Homology
Dlec1 DLEC1*   1:1 Homology
Egfr EGFR*   1:1 Homology
Erbb2 ERBB2*   1:1 Homology
Ercc6 ERCC6*   1:1 Homology
Fasl FASLG*   1:1 Homology
Irf1 IRF1*   1:1 Homology
Map3k8 MAP3K8*   1:1 Homology
Park2 PARK2*   1:1 Homology
Pik3ca PIK3CA*   1:1 Homology
Ppp2r1b PPP2R1B*   1:1 Homology
Rassf1 RASSF1*   1:1 Homology
Slc22a18 SLC22A18*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(Actb-KRAS*G12V,-luc)#Lche View 1 model
  Tg(SFTPC-EML4/ALK)502-4Hima View 1 model
  Tg(SFTPC-env)1Yhch View 1 model
  Tg(SFTPC-EZR/ROS1)AShiba View 1 model
  Tg(Utg-TAg)7593Fjd View 1 model
  Tg(Utg-TAg)7736Fjd View 1 model
  Tg(Utg-TAg)#Fjd View 1 model
References Disease References using Mouse Models (30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory