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Human Disease and Mouse Model Detail
Human Disease Down Syndrome
OMIM ID: 190685
Human Phenotype Ontology associations
View all models View ALL (22) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     DYRK1A Dyrk1a* View 5 models HomoloGene and HGNC
     DCR*   HGNC
GATA1* Gata1   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Dp(16Cbr1-Fam3b)1Rhr View 2 models
  Dp(16Hspa13-App)2Yah View 1 model
  Dp(16Lipi-Zbtb21)1TybEmcf View 1 model
  Rb(12.Ts171665Dn)2Cje View 1 model
  Tc(HSA21)1TybEmcf View 1 model
  Tg(DYRK1A)36Wjs View 1 model
  Tg(Dyrk1a)189N3Yah View 1 model
  Tg(MT1A-Dyrk1a)9Xest View 1 model
  Tg(MT1A-Dyrk1a)33Xest View 1 model
  Tg(MT1A-Dyrk1a)#Xest View 1 model
  Tg(RCAN1)M9Mapr View 1 model
  Ts(16C-tel)1Cje View 2 models
  Ts(1716)65Dn View 4 models
References Disease References using Mouse Models (74)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory