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Human Disease and Mouse Model Detail
Human Disease Down Syndrome
OMIM ID: 190685
View all models View ALL (20) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Dyrk1a* DYRK1A View 7 models 1:1 Homology
Rcan1* RCAN1 View 1 model 1:1 Homology
     Gata1 GATA1*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Dp(16Cbr1-Fam3b)1Rhr View 2 models
  Rb(12.Ts171665Dn)2Cje View 1 model
  Tc(HSA21)1TybEmcf View 1 model
  Tg(DYRK1A)36Wjs View 1 model
  Tg(Dyrk1a)189N3Yah View 1 model
  Tg(MT1A-Dyrk1a)9Xest View 1 model
  Tg(MT1A-Dyrk1a)33Xest View 1 model
  Tg(MT1A-Dyrk1a)#Xest View 1 model
  Tg(RCAN1)M9Mapr View 1 model
  Ts(16C-tel)1Cje View 2 models
  Ts(1716)65Dn View 4 models
References Disease References using Mouse Models (48)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory