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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pgr
progesterone receptor
MGI:97567
83 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Apctm1Rsmi/\Apctm1Rsmi
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal internal female genitalia morphology J:210095
abnormal oviduct morphology J:210095
endometrium hyperplasia J:210095
increased granulosa cell tumor incidence J:210095
increased ovary tumor incidence J:210095
increased reproductive system tumor incidence J:210095
ovary cyst J:210095
\Atg16l1tm1c(EUCOMM)Wtsi/\Atg16l1tm1c(EUCOMM)Wtsi
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		abnormal decidualization J:287978
decreased litter size J:287978
impaired embryo implantation J:287978
reduced female fertility J:287978
\Errfi1tm1Jwj/\Errfi1tm1Jwj
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ 		abnormal uterus morphology J:150007
endometrium hyperplasia J:150007
female infertility J:150007
increased endometrial carcinoma incidence J:150007
increased endometrial gland number J:150007
increased uterus weight J:150007
\Errfi1tm1Jwj/\Errfi1tm1Jwj
\Pgrtm2(cre)Lyd/\Pgr+
\Ptentm1Hwu/\Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		abnormal endometrium morphology J:162027
endometrium hyperplasia J:162027
increased endometrial carcinoma incidence J:162027
increased metastatic potential J:162027
increased uterus weight J:162027
premature death J:162027
\Ezh2tm2Sho/\Ezh2tm2Sho
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal endometrial gland morphology J:290765
abnormal endometrium morphology J:290765
abnormal parturition J:290765
abnormal uterine epithelium development J:290765
decreased litter size J:290765
decreased uterine NK cell number J:290765
dystocia J:290765
endometrium hyperplasia J:290765
enlarged uterine horn J:290765
increased endometrial gland number J:290765
reduced female fertility J:290765
\Foxa2tm1Khk/\Foxa2tm1Khk
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal decidualization J:165229
abnormal embryo invasion J:165229
abnormal endometrial gland development J:165229
abnormal uterus physiology J:165229
decreased endometrial gland number J:165229
decreased litter size J:165229
impaired embryo implantation J:165229
reduced female fertility J:165229
\Gata2tm1Sac/\Gata2tm1Sac
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ 		abnormal decidualization J:240902
abnormal endometrium morphology J:240902
abnormal uterus physiology J:240902
failure of embryo implantation J:240902
female infertility J:240902
\Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:218222
\Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?
\Pgrtm2(cre)Lyd/\Pgr+
\Ptentm1Hwu/\Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		abnormal uterus physiology J:218222
endometrium hyperplasia J:218222
increased papilloma incidence J:218222
increased uterus weight J:218222
premature death J:218222
\Gt(ROSA)26Sortm1(CAG-NR2F1)Mjts/\Gt(ROSA)26Sor+
\Nr2f2tm2.1Tsa/\Nr2f2tm2.1Tsa
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ 		normal reproductive system phenotype J:162256
\Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/\Gt(ROSA)26Sor+
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal embryo attachment J:233595
abnormal embryo development J:233595
abnormal maternal decidual layer morphology J:233595
abnormal placenta morphology J:233595
abnormal trophoblast giant cell proliferation J:233595
abnormal uterine-embryonic axis J:233595
abnormal uterus morphology J:233595
decreased litter size J:233595
decreased placental labyrinth size J:233595
impaired embryo implantation J:233595
impaired spacing of implantation sites J:233595
reduced female fertility J:233595
normal reproductive system phenotype J:233595
twin decidual capsule J:233595
\Gt(ROSA)26Sortm2(CAG-Nr5a1)Fjd/\Gt(ROSA)26Sor+
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ 		abnormal decidualization J:269597
abnormal endometrial gland development J:269597
abnormal endometrial gland morphology J:269597
abnormal endometrium morphology J:269597
abnormal uterus morphology J:269597
enlarged endometrial glands J:269597
enlarged uterine horn J:269597
female infertility J:269597
uterus cyst J:269597
uterus inflammation J:269597
\Hdac3tm1.1Eno/\Hdac3tm1.1Eno
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal decidualization J:269518
abnormal embryo attachment J:269518
abnormal endometrium morphology J:269518
abnormal uterine receptivity J:269518
abnormal uterus physiology J:269518
endometrium fibrosis J:269518
failure of embryo implantation J:269518
female infertility J:269518
normal homeostasis/metabolism phenotype J:269518
increased collagen level J:269518
normal reproductive system phenotype J:269518
\Klf5tm1Jaw/\Klf5tm1Jaw
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ 		abnormal decidualization J:179912
abnormal embryo attachment J:179912
abnormal uterine receptivity J:179912
decreased litter size J:179912
failure of embryo implantation J:179912
female infertility J:179912
normal homeostasis/metabolism phenotype J:179912
impaired embryo implantation J:179912
reduced female fertility J:179912
\Leprtm1.1Chua/\Leprtm1.1Chua
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129 * C57BL/6J * FVB/NJ 		abnormal embryo implantation J:324160
abnormal parturition J:324160
decreased litter size J:324160
delayed parturition J:324160
dystocia J:324160
normal embryo phenotype J:324160
normal homeostasis/metabolism phenotype J:324160
pup cannibalization J:324160
reduced female fertility J:324160
normal reproductive system phenotype J:324160
\Men1tm1.2Zqw/\Men1tm1.2Zqw
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal decidualization J:322043
abnormal DNA methylation J:322043
abnormal embryo development J:322043
abnormal placenta development J:322043
abnormal trophoblast giant cell morphology J:322043
decreased litter size J:322043
decreased uterine NK cell number J:322043
embryonic growth retardation J:322043
impaired embryo implantation J:322043
increased endometrial gland number J:322043
increased miscarriage rate J:322043
reduced female fertility J:322043
\Ncoa1tm1Bwo/\Ncoa1tm1Bwo
\Ncoa2tm1.1Ipc/\Ncoa2tm1.1Ipc
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129/Sv * 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		abnormal decidualization J:117006
\Ncoa2tm1.1Ipc/\Ncoa2tm1.1Ipc
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ 		abnormal branching of the mammary ductal tree J:117006
abnormal decidualization J:117006
failure of embryo implantation J:117006
female infertility J:117006
normal reproductive system phenotype J:117006
\Ncoa6tm3Jxu/\Ncoa6tm3Jxu
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129/Sv * C57BL/6 * SJL 		abnormal decidualization J:189065
abnormal luminal closure J:189065
abnormal uterine receptivity J:189065
female infertility J:189065
\Nr2f2tm2.1Tsa/\Nr2f2tm2.1Tsa
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ 		female infertility J:162256
\Pgrtm2(cre)Lyd/\Pgr+
\Trp53tm1Brn/\Trp53tm1Brn
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		normal reproductive system phenotype J:139053
\Pgrtm2(cre)Lyd/\Pgr+
\Ptentm1Hwu/\Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		abnormal uterus physiology J:162027
decreased uterus weight J:218222
endometrium hyperplasia J:162027
increased endometrial carcinoma incidence J:162027, J:218222
increased papilloma incidence J:218222
increased uterus weight J:162027, J:218222
premature death J:218222
\Pgrtm2(cre)Lyd/\Pgr+
\Ptentm1Hwu/\Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		endometrium hyperplasia J:139053
increased endometrial carcinoma incidence J:139053
premature death J:139053
\Pgrtm2(cre)Lyd/\Pgr+
\Ptentm1Hwu/\Ptentm1Hwu
\Trp53tm1Brn/\Trp53tm1Brn
involves: 129 * C57BL/6 		endometrium hyperplasia J:139053
enlarged uterus J:139053
increased endometrial carcinoma incidence J:139053
premature death J:139053
\Pgrtm2(cre)Lyd/\Pgr+
\Rbpjtm1Hon/\Rbpjtm1Hon
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal decidualization J:326956
\Pgrtm2(cre)Lyd/\Pgr+
\Criptotm2.2Mms/\Criptotm2.2Mms
involves: 129/Sv * C57BL/6N * CD-1 		abnormal decidualization J:324146
abnormal embryo attachment J:324146
abnormal endometrial gland morphology J:324146
abnormal luminal closure J:324146
abnormal pregnancy J:324146
abnormal uterine environment J:324146
abnormal uterine-embryonic axis J:324146
decreased litter size J:324146
delayed embryo implantation J:324146
endometrium inflammation J:324146
failure of embryo implantation J:324146
female infertility J:324146
reduced female fertility J:324146
\Pgrtm2(cre)Lyd/\Pgr+
\Ror1tm1.1Meg/\Ror1tm1.1Meg
\Ror2tm1.1Meg/\Ror2tm1.1Meg
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		abnormal embryo attachment J:233595
abnormal maternal decidual layer morphology J:233595
decreased litter size J:233595
reduced female fertility J:233595
\Pgrtm2(cre)Lyd/\Pgr+
\Wnt5atm1.1Tpy/\Wnt5atm1.1Tpy
involves: 129S1/Sv * 129X1/SvJ 		abnormal embryo attachment J:233595
abnormal embryo development J:233595
abnormal maternal decidual layer morphology J:233595
abnormal placenta morphology J:233595
abnormal trophoblast giant cell proliferation J:233595
abnormal uterine-embryonic axis J:233595
abnormal uterus morphology J:233595
decreased litter size J:233595
decreased placental labyrinth size J:233595
impaired embryo implantation J:233595
impaired spacing of implantation sites J:233595
reduced female fertility J:233595
normal reproductive system phenotype J:233595
twin decidual capsule J:233595
\Pgrmc1tm1.1Jjp/\Pgrmc1tm1.1Jjp
\Pgrmc2tm1.1Jjp/\Pgrmc2+
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		enlarged endometrial glands J:247103
\Pgrmc1tm1.1Jjp/\Pgrmc1tm1.1Jjp
\Pgrmc2tm1.1Jjp/\Pgrmc2tm1.1Jjp
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal endometrial gland morphology J:247103
abnormal endometrium morphology J:247103
decreased litter size J:247103
early reproductive senescence J:247103
enlarged endometrial glands J:247103
increased endometrial gland number J:247103
reduced female fertility J:247103
uterus cyst J:247103
\Pgrmc2tm1.1Jjp/\Pgrmc2+
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		enlarged endometrial glands J:247103
\Pgrmc2tm1.1Jjp/\Pgrmc2tm1.1Jjp
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal endometrial gland morphology J:247103
abnormal endometrium morphology J:247103
decreased circulating progesterone level J:247103
decreased litter size J:247103
decreased uterine NK cell number J:247103
early reproductive senescence J:247103
enlarged endometrial glands J:247103
increased endometrial gland number J:247103
reduced female fertility J:247103
uterus cyst J:247103
\Phb1tm1.1Bwo/\Phb1tm1.1Bwo
\Pgrtm2(cre)Lyd/?
involves: 129S7/SvEvBrd * C57BL/6 		abnormal endometrium morphology J:173884
abnormal uterus morphology J:173884
abnormal uterus size J:173884
decreased uterus weight J:173884
normal endocrine/exocrine gland phenotype J:173884
endometrium hypoplasia J:173884
female infertility J:173884
normal homeostasis/metabolism phenotype J:173884
thin uterine horn J:173884
\Phb2tm2.1Katz/\Phb2+
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ 		abnormal mammary gland duct morphology J:178347
\Phb2tm2.1Katz/\Phb2tm2.1Katz
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ 		abnormal mammary gland duct morphology J:178347
abnormal mammary gland morphology J:178347
normal reproductive system phenotype J:178347
\Tg(CMV-GAL4)1Shy/0
\Tg(Pgr)2Shy/0
Not Specified 		abnormal branching of the mammary ductal tree J:45538
abnormal mammary gland duct morphology J:45538
mammary gland duct hyperplasia J:45538
\Tg(CMV-GAL4)1Shy/0
\Tg(Pgr)3Shy/0
Not Specified 		abnormal mammary gland development J:83103
\Tsc2tm1.1Mjg/\Tsc2tm1.1Mjg
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129S1/Sv * 129X1/SvJ 		abnormal myometrium morphology J:221228
endometrium hyperplasia J:221228
enlarged uterus J:221228
increased endometrial gland number J:221228
increased lung tumor incidence J:221228
increased metastatic potential J:221228
increased uterus leiomyoma incidence J:221228
increased uterus weight J:221228
internal hemorrhage J:221228
\Vmn2r53em1Ktou/\Vmn2r53+
\Pgrtm1.1(cre)Shah/\Pgr+
involves: 129S/SvEv * BALB/cCrSlc * C57BL/6J 		decreased aggression towards male mice J:327623
\Vmn2r53em1Ktou/\Vmn2r53em1Ktou
\Pgrtm1.1(cre)Shah/\Pgr+
involves: 129S/SvEv * BALB/cCrSlc * C57BL/6J 		decreased aggression towards male mice J:327623
\Wnt7atm1.1Tesp/\Wnt7atm1.1Tesp
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL 		abnormal postimplantation uterine environment J:175291
absent endometrial glands J:175291
female infertility J:175291
\Wnt11tm1.1Khay/\Wnt11tm1.2Khay
\Pgrtm2(cre)Lyd/\Pgr+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal uterus physiology J:170159
increased endometrial gland number J:170159
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory