Errfi1^tm1Jwj
Targeted Allele Detail

Summary

• Symbol: Errfi1^tm1Jwj
• Name: ERBB receptor feedback inhibitor 1; targeted mutation 1, Jae-Wook Jeong
• MGI ID: MGI:3769404
• Synonyms: Errf1^f, Mig-6^flox
• Gene: Errfi1 Location: Chr4:150938376-150953349 bp, + strand Genetic Position: Chr4, 81.5 cM, cytoband E1
• Alliance: Errfi1^tm1Jwj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129106
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A frt-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4 and an additional loxP site was inserted upstream of exon 2. The neo cassette was subsequently removed by flp-mediated recombination. (J:129106)

Disease models

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Errfi1^tm1Jwj

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Errfi1 Mutation: 18 strains or lines available

References

• Original: J:129106 Jin N, et al., Generation of a Mig-6 conditional null allele. Genesis. 2007 Nov;45(11):716-21
• All: 17 reference(s)