Gt(ROSA)26Sor^{tm1(CAG-Errfi1)Jwj}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Errfi1)Jwj}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jae-Wook Jeong
• MGI ID: MGI:5707028
• Synonyms: Mig-6^LSL
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Errfi1)Jwj} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218222
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A construct consisting of a CAG promoter, floxed stop cassette and Errfi1 cDNA was inserted into the locus via homologous recombination. (J:218222)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:218222 Kim TH, et al., Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation. Cancer Res. 2014 Dec 15;74(24):7371-82
• All: 2 reference(s)