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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mstn
myostatin
MGI:95691
64 phenotypes from 11 alleles in 16 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
MstnCmpt/Mstn+
either: HCI or HCR
abnormal body composition J:43299
abnormal muscle morphology J:43299
increased body weight J:43299
increased skeletal muscle mass J:43299
MstnCmpt/MstnCmpt
BEH
impaired skeletal muscle contractility J:119757
increased skeletal muscle mass J:119757
Mstnlean/Mstnlean
C57BL/6J-Mstnlean
abnormal circulating tumor necrosis factor level J:146513
abnormal gluconeogenesis J:146513
abnormal glucose homeostasis J:146513
decreased adiponectin level J:146513
decreased body weight J:146513
decreased circulating cholesterol level J:146513
decreased circulating glucose level J:146513
decreased circulating insulin level J:146513
decreased circulating leptin level J:146513
decreased circulating triglyceride level J:146513
decreased circulating tumor necrosis factor level J:146513
decreased epididymal fat pad weight J:146513
decreased percent body fat/body weight J:146513
decreased susceptibility to diet-induced hepatic steatosis J:146513
improved glucose tolerance J:146513
increased gastrocnemius weight J:146513
increased insulin sensitivity J:146513
increased lean body mass J:146513
increased quadriceps weight J:146513
insulin resistance J:146513
Mstntm1.1Mgs/Mstntm1.1Mgs
involves: 129S1/Sv * 129X1/SvJ * C57BL * FVB/N
abnormal enzyme/coenzyme level J:184622
abnormal muscle physiology J:184622
abnormal skeletal muscle morphology J:184622
increased body weight J:184622
increased skeletal muscle weight J:184622
oxidative stress J:184622
skeletal muscle hypertrophy J:184622
Mstntm1.1Swel/Mstntm1.1Swel
involves: 129S7/SvEvBrd-Hprt1 * C57BL/6J * FVB/N
abnormal muscle physiology J:106054
decreased body weight J:106054
increased body weight J:106054
increased muscle weight J:106054
Mstntm1Mgs/Mstntm1Mgs
Tg(Ckmm-cre)5Khn/?
involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB
abnormal muscle morphology J:83122
increased body weight J:83122
increased muscle weight J:83122
increased skeletal muscle fiber size J:83122
skeletal muscle hypertrophy J:83122
Mstntm1Sjl/Mstn+
B6N.129-Mstntm1Sjl
abnormal hormone level J:240862
Mstntm1Sjl/Mstntm1Sjl
B6N.129-Mstntm1Sjl
abnormal hormone level J:240862
increased skeletal muscle fiber diameter J:132807
increased skeletal muscle fiber number J:132807
increased skeletal muscle mass J:132807
Mstntm1Sjl/Mstntm1Sjl
involves: 129S1/Sv * 129X1/SvJ
abnormal skeletal muscle fiber morphology J:158173
increased skeletal muscle fiber number J:158173
Mstntm1Sjl/Mstntm1Sjl
involves: 129S1/Sv * 129X1/SvJ * BALB/c
increased heart weight J:122391
Mstntm1Sjl/Mstntm1Sjl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal lipid level J:75178
abnormal postnatal growth/weight/body size J:40054
decreased circulating leptin level J:75178
decreased epididymal fat pad weight J:75178
decreased inguinal fat pad weight J:75178
decreased kidney weight J:75178
decreased liver weight J:75178
decreased parametrial fat pad weight J:75178
decreased retroperitoneal fat pad weight J:75178
decreased total body fat amount J:75178
increased body size J:40054
increased body weight J:75178
increased food intake J:75178
increased muscle weight J:40054
increased skeletal muscle fiber number J:40054
increased skeletal muscle fiber size J:40054
increased skeletal muscle mass J:40054
increased skeletal muscle size J:75178
Mstntm1Sjl/Mstntm1Sjl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
abnormal femur morphology J:105955
abnormal trochanter morphology J:105955
increased bone mineral content J:105955
increased bone mineral density of femur J:105955
increased compact bone thickness J:105955
increased quadriceps weight J:105955
short femur J:105955
Mstntm1Swel/Mstntm1Swel
Tg(CAG-cre/Esr1*)5Amc/?
involves: 129S7/SvEvBrd-Hprt1 * C57BL/6 * CBA
increased skeletal muscle fiber diameter J:121233
increased skeletal muscle mass J:121233
Mstntm2Sjl/Mstn+
B6.129-Mstntm2Sjl
increased skeletal muscle mass J:132807
Mstntm2Sjl/Mstntm2Sjl
B6.129-Mstntm2Sjl
increased skeletal muscle fiber diameter J:132807
increased skeletal muscle fiber number J:132807
increased skeletal muscle mass J:132807
Mstntm3.1Sjl/Mstntm3.1Sjl
B6N.129S6(FVB)-Mstntm3.1Sjl/Sjl
normal muscle phenotype J:240862
Mstntm3.1Sjl/Mstntm3.1Sjl
Tg(CDX2-cre)101Erf/0
B6.Cg-Mstntm3.1Sjl Tg(CDX2-cre)101Erf/Sjl
abnormal hormone level J:240862
abnormal skeletal muscle morphology J:240862
increased skeletal muscle weight J:240862
skeletal muscle hyperplasia J:240862
skeletal muscle hypertrophy J:240862
Tg(Ckm*-Mstn)1Nfg/?
involves: BALB/c * C57BL/6
normal cardiovascular system phenotype J:122391
decreased skeletal muscle mass J:123052
Tg(Ckm-Mstn)1Nfg/?
involves: BALB/c * C57BL/6
abnormal heart left ventricle morphology J:122391
abnormal myocardium layer morphology J:123052
abnormal skeletal muscle fiber morphology J:123052
decreased body weight J:122391, J:123052
decreased heart weight J:122391
decreased skeletal muscle fiber size J:123052
decreased skeletal muscle mass J:123052
increased epididymal fat pad weight J:123052

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory