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MstnCmpt
Spontaneous Allele Detail
Summary
Symbol: MstnCmpt
Name: myostatin; compact
MGI ID: MGI:1857404
Synonyms: Berlin High Line, BEHC/C), Compact, MstnCmpt-dl1Abc
Gene: Mstn  Location: Chr1:53100799-53107238 bp, + strand  Genetic Position: Chr1, 26.99 cM
Alliance: MstnCmpt page
Mutation
origin
Strain of Origin:  HCR
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsA 12 bp deletion of residues 775 to 786, corresponding to amino acids 224 to 228. This mutation affects the propeptide region which may play a role in the proper targeting, folding or secretion of the encoded protein. (J:48785)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mstn Mutation:  33 strains or lines available
References
Original:  J:43299 Varga L, et al., Inheritance and mapping of Compact (Cmpt), a new mutation causing hypermuscularity in mice. Genetics. 1997 Oct;147(2):755-64
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory