Mstn^Cmpt
Spontaneous Allele Detail

Summary

• Symbol: Mstn^Cmpt
• Name: myostatin; compact
• MGI ID: MGI:1857404
• Synonyms: Berlin High Line, BEH^C/C), Compact, Mstn^Cmpt-dl1Abc
• Gene: Mstn Location: Chr1:53100799-53107238 bp, + strand Genetic Position: Chr1, 26.99 cM
• Alliance: Mstn^Cmpt page

Mutation origin

• Strain of Origin: HCR

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: A 12 bp deletion of residues 775 to 786, corresponding to amino acids 224 to 228. This mutation affects the propeptide region which may play a role in the proper targeting, folding or secretion of the encoded protein. (J:48785)
• Inheritance: Semidominant

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mstn Mutation: 33 strains or lines available

References

• Original: J:43299 Varga L, et al., Inheritance and mapping of Compact (Cmpt), a new mutation causing hypermuscularity in mice. Genetics. 1997 Oct;147(2):755-64
• All: 12 reference(s)