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Mstntm1Mgs
Targeted Allele Detail
Summary
Symbol: Mstntm1Mgs
Name: myostatin; targeted mutation 1, Michel Georges
MGI ID: MGI:2661073
Synonyms: MSTNflox
Gene: Mstn  Location: Chr1:53100799-53107238 bp, + strand  Genetic Position: Chr1, 26.99 cM
Alliance: Mstntm1Mgs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83122
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsFlanking loxP sites and a neomycin resistance cassette were introduced to exon 3 via homologous recombination. (J:83122)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mstn Mutation:  33 strains or lines available
References
Original:  J:83122 Grobet L, et al., Modulating skeletal muscle mass by postnatal, muscle-specific inactivation of the myostatin gene. Genesis. 2003 Apr;35(4):227-38
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory