Phenotypes associated with this allele

• Allele Symbol: Mstn^tm1Mgs
• Allele Name: targeted mutation 1, Michel Georges
• Allele ID: MGI:2661073
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Mstn^tm1Mgs/Mstn^tm1Mgs Tg(Ckmm-cre)5Khn/?	involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB	MGI:2661075

Genotype
MGI:2661075

cn1

• Allelic Composition: Mstn^tm1Mgs/Mstn^tm1Mgs; Tg(Ckmm-cre)5Khn/?
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:83122 )

• mutants weigh 23% and 26% more than controls at 2 months and 5 months of age, respectively

muscle

abnormal muscle morphology ( J:83122 )

• generalized muscle hypertrophy, resulting in a 'double-muscling' phenotype

• superficial muscle layers exhibit a more severe hypertrophy than the deep layers

increased skeletal muscle fiber size ( J:83122 )

increased muscle weight ( J:83122 )

skeletal muscle hypertrophy ( J:83122 )