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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Erbb3
erb-b2 receptor tyrosine kinase 3
MGI:95411
16 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
ApcMin/Apc+
Erbb3tm1.1Dwt/Erbb3tm2.1Dwt
Tg(Vil1-cre)997Gum/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL 		decreased tumor incidence J:152703
normal digestive/alimentary phenotype J:152703
intestine polyps J:152703
Erbb2tm1Cbm/Erbb2+
Erbb3tm2Cbm/Erbb3+
Nrg1tm1Cbm/Nrg1+
involves: 129P2/OlaHsd 		abnormal myelination J:90038
abnormal nerve conduction J:90038
Erbb3msp1/Erbb3msp1
Sox10tm1Weg/Sox10+
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J 		embryonic lethality during organogenesis, incomplete penetrance J:138775
hypopigmentation J:138775
lethality throughout fetal growth and development, incomplete penetrance J:138775
preweaning lethality, complete penetrance J:138775
Erbb3tm1.1(ERBB3)Mul/Erbb3+
Tg(MMTV-Erbb2*)NDL2-5Mul/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		increased mammary gland tumor incidence J:189292
increased tumor latency J:189292
Erbb3tm1.1(ERBB3)Mul/Erbb3tm1.1(ERBB3)Mul
Tg(MMTV-Erbb2*)NDL2-5Mul/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		decreased metastatic potential J:189292
increased mammary gland tumor incidence J:189292
increased tumor latency J:189292
Erbb3tm2Cbm/Erbb3tm3Cbm
Erbb4tm1Fej/Erbb4tm1Fej
Cnptm1(cre)Kan/?
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal myelination J:145464
normal nervous system phenotype J:145464
postnatal lethality, complete penetrance J:145464
Erbb3tm3Cbm/Erbb3tm3Cbm
Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky/?
Tg(Dhh-cre)1Mejr/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal myelination J:207470
Erbb3tm3Cbm/Erbb3tm3Cbm
Gt(ROSA)26Sortm8(Map2k1*,EGFP)Rsky/?
Tg(Dhh-cre)1Mejr/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal myelination J:207470
decreased myelin sheath thickness J:207470
hypermyelination J:207470
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory