154 phenotypes from 16 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Col1a1Aga2/Col1a1+ C3HeB/FeJ-Col1a1Aga2	abnormal blood gas level	J:185988
	abnormal blood vessel morphology	J:185988
	abnormal cardiovascular system physiology	J:185988
	abnormal cell morphology	J:185988
	abnormal endoplasmic reticulum morphology	J:185988
	abnormal Golgi apparatus morphology	J:185988
	abnormal heart electrocardiography waveform feature	J:185988
	abnormal heart septum morphology	J:185988
	abnormal myocardium layer morphology	J:185988
	decreased body weight	J:185988
	decreased ventricle muscle contractility	J:185988
	heart right ventricle hypertrophy	J:185988
	increased QRS amplitude	J:185988
	lung inflammation	J:185988
	postnatal lethality, incomplete penetrance	J:185988
	pulmonary alveolar hemorrhage	J:185988
	rib fractures	J:185988
Col1a1Aga2/Col1a1+ involves: C3HeB/FeJ * C57BL/6J	abnormal adipose tissue distribution	J:129569
	abnormal compact bone lamellar structure	J:129569
	abnormal dermal layer morphology	J:129569
	abnormal enzyme/coenzyme level	J:129569
	abnormal femur morphology	J:129569
	abnormal fibula morphology	J:129569
	abnormal hormone level	J:129569
	abnormal ischium morphology	J:129569
	abnormal osteoblast morphology	J:129569
	abnormal osteoblast physiology	J:129569
	abnormal pubis morphology	J:129569
	abnormal skeleton morphology	J:129569
	decreased body length	J:129569
	decreased body size	J:129569
	decreased body weight	J:129569
	decreased bone mineral content	J:129569
	decreased bone mineral density	J:129569
	decreased circulating alkaline phosphatase level	J:129569
	decreased diameter of femur	J:129569
	decreased litter size	J:129569
	fragile skeleton	J:129569
	hemorrhage	J:129569
	increased circulating parathyroid hormone level	J:129569
	increased osteoblast apoptosis	J:129569
	intracranial hemorrhage	J:129569
	kyphoscoliosis	J:129569
	postnatal lethality, incomplete penetrance	J:129569
	short femur	J:129569
	thin neurocranium	J:129569
Col1a1Aga2/Col1a1Aga2 involves: C3HeB/FeJ * C57BL/6J	embryonic lethality, complete penetrance	J:129569
Col1a1m1Btlr/Col1a1m1Btlr C57BL/6J-Col1a1m1Btlr	abnormal autopod morphology	J:253622
	abnormal bone collagen fibril morphology	J:253622
	abnormal femur morphology	J:253622
	abnormal gait	J:132554
	abnormal locomotor behavior	J:253622
	abnormal tibia morphology	J:253622
	abnormal trabecular bone morphology	J:253622
	decreased body weight	J:253622
	decreased bone mass	J:132554
	decreased compact bone thickness	J:253622
	decreased hydroxyproline level	J:253622
	decreased length of long bones	J:253622
	fragile skeleton	J:253622
	hemorrhage	J:132554
	hindlimb paralysis	J:132554, J:253622
	short limbs	J:253622
	spinal hemorrhage	J:132554
Col1a1M1Jrt/Col1a1+ involves: C3H/HeJ * C57BL/6J	abnormal motor coordination/balance	J:216423
	decreased bone mineral density	J:216423
	fragile skeleton	J:216423
	weakness	J:216423
Col1a1M1Jrt/Col1a1+ involves: C3H/HeJ * C57BL/6J * FVB/NJ	abnormal bone collagen fibril morphology	J:216423
	abnormal bone mineralization	J:216423
	abnormal bone trabecula morphology	J:216423
	abnormal compact bone morphology	J:216423
	abnormal cutaneous collagen fibril morphology	J:216423
	abnormal dentin mineralization	J:216423
	abnormal extracellular matrix morphology	J:216423
	abnormal femur morphology	J:216423
	abnormal fertility/fecundity	J:216423
	abnormal gait	J:216423
	abnormal osteoblast morphology	J:216423
	abnormal tail movements	J:216423
	abnormal tendon collagen fibril morphology	J:216423
	decreased body size	J:216423
	decreased body weight	J:216423
	decreased bone mineral content	J:216423
	decreased bone mineral density	J:216423
	decreased bone strength	J:216423
	decreased bone trabecula number	J:216423
	decreased bone trabecular spacing	J:216423
	decreased collagen level	J:216423
	decreased percent body fat/body weight	J:216423
	decreased skin tensile strength	J:216423
	decreased tendon stiffness	J:216423
	decreased trabecular bone thickness	J:216423
	decreased trabecular bone volume	J:216423
	fragile skeleton	J:216423
	normal hearing/vestibular/ear phenotype	J:216423
	normal homeostasis/metabolism phenotype	J:216423
	increased bone resorption	J:216423
	increased bone trabecular spacing	J:216423
	increased osteoblast cell number	J:216423
	kyphosis	J:216423
	myocardium hypertrophy	J:216423
	osteoarthritis	J:216423
	thin body	J:216423
	thin tail	J:216423
Col1a1M1Jrt/Col1a1+ involves: C57BL/6 * FVB/N	abnormal autopod morphology	J:228439
	abnormal bone healing	J:228439
	abnormal locomotor behavior	J:228439
	abnormal mechanical nociception	J:228439
	abnormal olecranon morphology	J:228439
	abnormal pelvic girdle bone morphology	J:228439
	abnormal vertebral column morphology	J:228439
	arthritis	J:228439
	atlanto-occipital joint dislocation	J:228439
	decreased body weight	J:228439
	decreased bone trabecula number	J:228439
	decreased bone volume	J:228439
	decreased compact bone thickness	J:228439
	decreased length of long bones	J:228439
	decreased locomotor activity	J:228439
	decreased thermal nociceptive threshold	J:228439
	decreased vertical activity	J:228439
	fragile skeleton	J:228439
	osteophytes	J:228439
	scoliosis	J:228439
	short femur	J:228439
Col1a1M1Jrt/Col1a1M1Jrt involves: C3H/HeJ * C57BL/6J	prenatal lethality, complete penetrance	J:216423
Col1a1Mov13/Col1a1+ C57BL/6-Col1a1Mov13	abnormal coat/hair pigmentation	J:6514
Col1a1Mov13/Col1a1+ involves: C57BL/6	abnormal compact bone lamellar structure	J:107045
	abnormal compact bone morphology	J:107045
	abnormal dermal layer morphology	J:107045
	fragile skeleton	J:107045
	impaired hearing	J:107045
	increased susceptibility to age-related hearing loss	J:107045
Col1a1Mov13/Col1a1Mov13 C57BL/6-Col1a1Mov13	decreased bone ossification	J:16630
	delayed bone ossification	J:16630
Col1a1Mov13/Col1a1Mov13 involves: C57BL/6	embryonic growth arrest	J:6979
	embryonic lethality during organogenesis, complete penetrance	J:6979
Col1a1tm1(tetO-cas9)Sho/Col1a1tm1(tetO-cas9)Sho B6.Cg-Col1a1tm1(tetO-cas9)Sho	no abnormal phenotype detected	J:101977
Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:167431
Col1a1tm1.1Jcm/Col1a1+ either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)	abnormal chest morphology	J:59168
	abnormal cranium morphology	J:59168
	abnormal dental pulp cavity morphology	J:59168
	abnormal ischium morphology	J:59168
	abnormal limb morphology	J:59168
	abnormal long bone morphology	J:59168
	abnormal maxilla morphology	J:59168
	abnormal neurocranium morphology	J:59168
	abnormal pelvic girdle bone morphology	J:59168
	abnormal rib morphology	J:59168
	abnormal thoracic cage shape	J:59168
	abnormal turbinate morphology	J:59168
	abnormal vertebral body morphology	J:59168
	decreased body size	J:59168
	decreased bone mineralization	J:59168
	lung hemorrhage	J:59168
	neonatal lethality, incomplete penetrance	J:59168
	respiratory distress	J:59168
	rib fractures	J:59168
	thin neurocranium	J:59168
	thin ribs	J:59168
Col1a1tm1.1Jcm/Col1a1+ involves: 129X1/SvJ	abnormal neurocranium morphology	J:59168
	decreased body size	J:59168
	decreased bone mineralization	J:59168
	neonatal lethality, incomplete penetrance	J:59168
	respiratory distress	J:59168
	rib fractures	J:59168
	short vertebral body	J:59168
Col1a1tm1Bst/Col1a1tm1Bst involves: 129P2/OlaHsd * C57BL/6	abnormal aorta elastic tissue morphology	J:92016
	abnormal aorta tunica adventitia morphology	J:92016
	aneurysm	J:92016
	aortic dissection	J:92016
	hemorrhage	J:92016
	premature death	J:92016
Col1a1tm1Dab/Col1a1tm1Dab C.129S6-Col1a1tm1Dab	abnormal liver morphology	J:170561
	decreased susceptibility to injury	J:170561
Col1a1tm1Jae/Col1a1+ either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	abnormal uterus morphology	J:26504
	decreased litter size	J:26504
	focal hair loss	J:26504
	thick dermal layer	J:26504
Col1a1tm1Jae/Col1a1tm1Jae either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	abnormal myometrium morphology	J:26504
	abnormal uterus morphology	J:26504
	decreased litter size	J:26504
	focal hair loss	J:26504
	thick dermal layer	J:26504
Col1a1tm1Jae/Col1a1tm1Jae involves: 129S4/SvJae * C57BL/6	abnormal limb bone morphology	J:53079
	abnormal neurocranium morphology	J:90884
	abnormal osteoblast differentiation	J:85591, J:90884
	abnormal osteoclast physiology	J:53079
	abnormal osteocyte lacuna morphology	J:90884
	abnormal osteocyte morphology	J:90884
	decreased body weight	J:82606
	failure of bone resorption	J:85591
	increased osteoblast apoptosis	J:90884
	increased osteocyte apoptosis	J:90884
	joint contracture	J:53079
	ocular hypertension	J:82606
	osteopetrosis	J:85591
	normal skeleton phenotype	J:85591
	thick neurocranium	J:90884
	normal vision/eye phenotype	J:82606
Col1a1tm1Jcm/Col1a1+ either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)	abnormal neurocranium morphology	J:59168
	neonatal lethality, complete penetrance	J:59168
	respiratory distress	J:59168
	rib fractures	J:59168
	short vertebral body	J:59168
Col1a1tm2.1Bst/Col1a1tm2.1Bst involves: 129/Sv * 129P2/OlaHsd	preweaning lethality, incomplete penetrance	J:73906
Col1a1tm17(tetO-GFP,-cas9*)Slowe/Col1a1+ involves: 129S4/SvJae * C57BL/6	normal digestive/alimentary phenotype	J:222595
Col1a1tm18(tetO-GFP,-cas9*)Slowe/Col1a1+ involves: 129S4/SvJae * C57BL/6	normal digestive/alimentary phenotype	J:222595
Col1a1tm19(tetO-GFP,-cas9*)Slowe/Col1a1+ involves: 129S4/SvJae * C57BL/6	normal digestive/alimentary phenotype	J:222595
Col1a1tm20(tetO-GFP,-cas9*D10A)Slowe/Col1a1+ involves: 129S4/SvJae * C57BL/6	normal digestive/alimentary phenotype	J:222595