35 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aplp2tm1Dbo/Aplp2tm1Dbo Apptm1.1Zhe/Apptm1.1Zhe Chattm2(cre)Lowl/Chat+ involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J	abnormal neuromuscular synapse morphology	J:152457
Brsk2tm2.1Jrs/Brsk2tm2.1Jrs Chattm1(cre)Lowl/Chat+ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ	normal nervous system phenotype	J:201695
Chattm2(cre)Lowl/Chat+ Mecp2tm2Bird/Y involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	abnormal respiration	J:241788
	apnea	J:241788
	normal behavior/neurological phenotype	J:241788
	normal cardiovascular system phenotype	J:241788
	normal homeostasis/metabolism phenotype	J:241788
Chattm2(cre)Lowl/Chat+ Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NCr	abnormal inhibitory postsynaptic currents	J:202884
Chattm2(cre)Lowl/Chat+ Mapttm3(Sema3e)Arbr/Mapttm3(Sema3e)Arbr involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	abnormal motor neuron innervation pattern	J:149553
	normal behavior/neurological phenotype	J:149553
Chattm2(cre)Lowl/Chat+ Plxna2tm1a(EUCOMM)Wtsi/Plxna2tm1Hfu involves: 129S6/SvEvTac * C57BL/6N * CBA/JNCrlj	abnormal amacrine cell morphology	J:202884
	abnormal dendrite morphology	J:202884
	abnormal retina inner plexiform layer morphology	J:202884
Chattm2(cre)Lowl/Chat+ Mapttm2(FUS)Neas/Mapt+ B6.129-Mapttm2(FUS)Neas Chattm2(cre)Lowl	abnormal neuromuscular synapse morphology	J:232167
	motor neuron degeneration	J:232167
Chattm2(cre)Lowl/Chat+ Mapttm3(FUS)Neas/Mapt+ B6.129-Mapttm3(FUS)Neas Chattm2(cre)Lowl	abnormal neuromuscular synapse morphology	J:232167
	motor neuron degeneration	J:232167
Chattm2(cre)Lowl/Chat+ Cpeb2tm1.1Yshu/Cpeb2tm1.1Yshu involves: C57BL/6 * C57BL/6J * C57BL/6NJ * SJL/J	abnormal breathing pattern	J:237513
	abnormal whole-body plethysmography	J:237513
	apnea	J:237513
	decreased pulmonary respiratory rate	J:237513
	increased acetylcholine level	J:237513
	increased airway responsiveness	J:237513
	increased brain choline acetyltransferase activity	J:237513
Chattm2(cre)Lowl/Chat+ Stmn2em2Jmi/Stmn2em2Jmi involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N	abnormal neuromuscular synapse morphology	J:337175
	abnormal neuron morphology	J:337175
	decreased grip strength	J:337175
	preweaning lethality, incomplete penetrance	J:337175
Fustm1a(EUCOMM)Wtsi/Fustm1c(EUCOMM)Wtsi Chattm2(cre)Lowl/Chat+ involves: 129S6/SvEvTac * C3H * C57BL/6 * C57BL/6N	normal nervous system phenotype	J:232167
Mc4rtm1Lowl/Mc4rtm1Lowl Chattm1(cre)Lowl/Chat+ involves: 129S4/SvJae * 129S6/SvEvTac	hypertension	J:193452
	increased circulating insulin level	J:193452
Mc4rtm2Lowl/Mc4rtm2Lowl Chattm1(cre)Lowl/Chat+ Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ involves: 129S6/SvEvTac * C57BL/6NCr	abnormal nervous system electrophysiology	J:193452
	normal nervous system phenotype	J:193452
Mecp2tm1Jae/Y Chattm2(cre)Lowl/Chat+ involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J	abnormal heartbeat	J:241788
	normal behavior/neurological phenotype	J:241788
	decreased body temperature	J:241788
	decreased heart rate	J:241788
	increased heart rate variability	J:241788
	increased response of heart to induced stress	J:241788
	premature death	J:241788
	prolonged QT interval	J:241788
	normal respiratory system phenotype	J:241788
	ventricular premature beat	J:241788
	ventricular tachycardia	J:241788