Braftm1(ARAF)Urr/Braftm1(ARAF)Urr
involves: 129S1/Sv * C57BL/6
|
embryonic lethality during organogenesis, incomplete penetrance |
J:112971
|
|
increased apoptosis |
J:112971
|
Braftm1(ARAF)Urr/Braftm1(ARAF)Urr
involves: 129S1/Sv * C57BL/6 * CD-1
|
abnormal cerebral cortex pyramidal cell morphology |
J:112971
|
|
abnormal somatosensory cortex morphology |
J:112971
|
|
abnormal stratification in cerebral cortex |
J:112971
|
|
abnormal telencephalon development |
J:112971
|
|
abnormal visual cortex morphology |
J:112971
|
|
decreased body weight |
J:112971
|
|
decreased embryo size |
J:112971
|
|
decreased spleen weight |
J:112971
|
|
decreased thymus weight |
J:112971
|
|
embryonic lethality during organogenesis, incomplete penetrance |
J:112971
|
|
premature death |
J:112971
|
|
thin cerebral cortex |
J:112971
|
Braftm1.1Brd/Braf+
Tg(Vil1-cre)997Gum/0
involves: 129S7/SvEvBrd * C57BL/6 * SJL
|
abnormal crypts of Lieberkuhn morphology |
J:199307
|
|
abnormal intestinal epithelium morphology |
J:199307
|
|
abnormal intestinal mucosa morphology |
J:199307
|
|
abnormal large intestine crypts of Lieberkuhn morphology |
J:199307
|
|
abnormal large intestine morphology |
J:199307
|
|
abnormal small intestinal villus morphology |
J:199307
|
|
abnormal small intestine morphology |
J:199307
|
|
branched small intestinal villi |
J:199307
|
|
increased carcinoma incidence |
J:199307
|
|
increased gastrointestinal tumor incidence |
J:199307
|
|
increased intestinal adenoma incidence |
J:199307
|
|
increased large intestine length |
J:199307
|
|
increased small intestine length |
J:199307
|
|
intestine polyps |
J:199307
|
Braftm1.1Eyc/Braftm1.1Eyc
either: (involves: 129S2/SvPas * FVB/N ) or (involves: 129S2/SvPas * BALB/c * C57BL/6)
|
normal
behavior/neurological phenotype |
J:168330
|
Braftm1.1Sva/Braftm1.1Sva
involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ
|
abnormal placenta labyrinth morphology |
J:105998
|
|
abnormal placenta morphology |
J:105998
|
|
abnormal placental labyrinth vasculature morphology |
J:105998
|
|
abnormal spongiotrophoblast layer morphology |
J:105998
|
|
abnormal trophoblast layer morphology |
J:105998
|
|
decreased embryo size |
J:105998
|
|
embryonic lethality during organogenesis, complete penetrance |
J:105998
|
Braftm1.1Sva/Braftm1.1Sva
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
embryonic growth retardation |
J:121660
|
|
embryonic lethality during organogenesis, complete penetrance |
J:121660
|
|
increased neuron apoptosis |
J:121660
|
Braftm1.1Wds/Braftm1.1Wds
involves: 129P2/OlaHsd * C57BL/6
|
embryonic growth retardation |
J:121660
|
|
embryonic lethality during organogenesis, complete penetrance |
J:121660
|
|
increased neuron apoptosis |
J:121660
|
Braftm1Bbd/Braf+
B6.129-Braftm1Bbd
|
abnormal basicranium morphology |
J:170095
|
|
abnormal cell morphology |
J:170095
|
|
abnormal frontal bone morphology |
J:170095
|
|
abnormal immune system physiology |
J:170095
|
|
abnormal kidney morphology |
J:170095
|
|
abnormal mating frequency |
J:170095
|
|
abnormal neurocranium morphology |
J:170095
|
|
abnormal pancreatic acinar cell morphology |
J:170095
|
|
abnormal parietal bone morphology |
J:170095
|
|
abnormal skin sebaceous gland morphology |
J:170095
|
|
abnormal thymus morphology |
J:170095
|
|
cataract |
J:170095
|
|
decreased body size |
J:170095
|
|
decreased body weight |
J:170095
|
|
decreased creatinine clearance |
J:170095
|
|
decreased thymocyte number |
J:170095
|
|
decreased white adipose tissue amount |
J:170095
|
|
enlarged heart |
J:170095
|
|
hyperactivity |
J:170095
|
|
increased locomotor activity |
J:170095
|
|
increased splenocyte apoptosis |
J:170095
|
|
increased thymocyte apoptosis |
J:170095
|
|
oliguria |
J:170095
|
|
premature death |
J:170095
|
|
round head |
J:170095
|
|
shortened head |
J:170095
|
|
thymus atrophy |
J:170095
|
Braftm1Bbd/Braf+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
abnormal basicranium morphology |
J:170095
|
|
abnormal cell morphology |
J:170095
|
|
abnormal frontal bone morphology |
J:170095
|
|
abnormal immune system physiology |
J:170095
|
|
abnormal kidney morphology |
J:170095
|
|
abnormal mating frequency |
J:170095
|
|
abnormal neurocranium morphology |
J:170095
|
|
abnormal pancreatic acinar cell morphology |
J:170095
|
|
abnormal parietal bone morphology |
J:170095
|
|
abnormal skin sebaceous gland morphology |
J:170095
|
|
abnormal thymus morphology |
J:170095
|
|
cataract |
J:170095
|
|
decreased body size |
J:170095
|
|
decreased body weight |
J:170095
|
|
decreased thymocyte number |
J:170095
|
|
decreased white adipose tissue amount |
J:170095
|
|
enlarged heart |
J:170095
|
|
hyperactivity |
J:170095
|
|
increased circulating noradrenaline level |
J:170095
|
|
increased locomotor activity |
J:170095
|
|
increased splenocyte apoptosis |
J:170095
|
|
increased thymocyte apoptosis |
J:170095
|
|
postnatal lethality, incomplete penetrance |
J:170095
|
|
premature death |
J:170095
|
|
round head |
J:170095
|
|
shortened head |
J:170095
|
|
thymus atrophy |
J:170095
|
Braftm1Bbd/Braf+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CD-1
|
abnormal astrocyte morphology |
J:170095
|
|
abnormal basicranium morphology |
J:170095
|
|
abnormal cell morphology |
J:170095
|
|
abnormal dermal melanocyte morphology |
J:170095
|
|
abnormal frontal bone morphology |
J:170095
|
|
abnormal immune system physiology |
J:170095
|
|
abnormal kidney morphology |
J:170095
|
|
abnormal mating frequency |
J:170095
|
|
abnormal neurocranium morphology |
J:170095
|
|
abnormal pancreatic acinar cell morphology |
J:170095
|
|
abnormal parietal bone morphology |
J:170095
|
|
abnormal skin sebaceous gland morphology |
J:170095
|
|
abnormal thymus morphology |
J:170095
|
|
cataract |
J:170095
|
|
convulsive seizures |
J:170095
|
|
decreased body size |
J:170095
|
|
decreased body weight |
J:170095
|
|
decreased thymocyte number |
J:170095
|
|
decreased white adipose tissue amount |
J:170095
|
|
enlarged heart |
J:170095
|
|
heart hyperplasia |
J:170095
|
|
hyperactivity |
J:170095
|
|
increased cardiac muscle contractility |
J:170095
|
|
increased gland tumor incidence |
J:170095
|
|
increased locomotor activity |
J:170095
|
|
increased lung adenoma incidence |
J:170095
|
|
increased metastatic potential |
J:170095
|
|
increased pheochromocytoma incidence |
J:170095
|
|
increased splenocyte apoptosis |
J:170095
|
|
increased thymocyte apoptosis |
J:170095
|
|
premature death |
J:170095
|
|
round head |
J:170095
|
|
shortened head |
J:170095
|
|
tachypnea |
J:170095
|
|
thymus atrophy |
J:170095
|
Braftm1Cpri/Braf+
involves: 129P2/OlaHsd
|
increased cell proliferation |
J:187371
|
|
increased lung adenoma incidence |
J:187371
|
|
increased lung tumor incidence |
J:187371
|
Braftm1Cpri/Braf+
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
abnormal liver morphology |
J:104375
|
|
decreased bone marrow cell number |
J:104375
|
|
decreased erythrocyte cell number |
J:104375
|
|
decreased leukocyte cell number |
J:104375
|
|
enlarged spleen |
J:104375
|
|
extramedullary hematopoiesis |
J:104375
|
|
increased leukemia incidence |
J:104375
|
|
premature death |
J:104375
|
Braftm1Cpri/Braf+
Tg(CMV-cre)1Cgn/0
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
|
embryonic lethality between implantation and somite formation, complete penetrance |
J:104375
|
Braftm1Cpri/Braf+
Scn10atm2(cre)Jwo/Scn10a+
involves: 129 * 129P2/OlaHsd
|
abnormal dorsal root ganglion morphology |
J:205122
|
|
abnormal innervation |
J:205122
|
|
abnormal nervous system electrophysiology |
J:205122
|
|
abnormal neuron physiology |
J:205122
|
|
normal
behavior/neurological phenotype |
J:205122
|
|
enhanced behavioral response to xenobiotic |
J:205122
|
|
excessive scratching |
J:205122
|
|
skin lesions |
J:205122
|
Braftm1Cpri/Braftm1Cpri
involves: 129P2/OlaHsd * C57BL/6
|
increased fibroblast proliferation |
J:104375
|
Braftm1Cpri/Braftm1Cpri
Tg(TPO-cre)1Shk/0
involves: 129P2/OlaHsd * FVB/NCr
|
decreased activity of thyroid gland |
J:168249
|
|
decreased body weight |
J:168249
|
|
increased circulating thyroid-stimulating hormone level |
J:168249
|
|
increased circulating thyroxine level |
J:168249
|
|
increased thyroid carcinoma incidence |
J:168249
|
|
increased thyroid tumor incidence |
J:168249
|
Braftm1Cpri/Braftm1Cpri
Tg(Tyr-cre/ERT2)1Lru/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
hyperpigmentation |
J:147434
|
|
increased melanoma incidence |
J:147434
|
|
increased skin tumor incidence |
J:147434
|
|
spontaneous skin ulceration |
J:147434
|
Braftm1Mmcm/Braf+
involves: 129P2/OlaHsd
|
increased lung adenocarcinoma incidence |
J:121715
|
|
increased lung adenoma incidence |
J:121715
|
|
increased lung tumor incidence |
J:121715
|
|
lung epithelium hyperplasia |
J:121715
|
|
premature death |
J:121715
|
Braftm1Mmcm/Braf+
involves: 129P2/OlaHsd
|
no abnormal phenotype detected |
J:121715
|
Braftm1Mmcm/Braf+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
increased thyroid carcinoma incidence |
J:208854
|
Braftm1Mmcm/Braf+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129P2/OlaHsd * C57BL/6 * FVB
|
normal
neoplasm |
J:239472
|
Braftm1Mmcm/Braf+
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129P2/OlaHsd * FVB
|
abnormal melanocyte morphology |
J:151023
|
|
skin lesions |
J:151023
|
Braftm1Mmcm/Braf+
Polr2atm1(cre/ERT2)Bbd/Polr2a+
involves: 129P2/OlaHsd * C57BL/6 * SJL
|
increased lung adenoma incidence |
J:121715
|
Braftm1Mmcm/Braf+
Tg(TPO-cre/ERT2)1139Tyj/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac
|
increased thyroid carcinoma incidence |
J:208854
|
|
respiratory failure |
J:208854
|
Braftm1Mmcm/Braf+
Tg(Tg-cre/ERT2)#Mmcm/0
involves: 129P2/OlaHsd
|
abnormal thyroid follicle morphology |
J:172205
|
|
abnormal thyroid gland morphology |
J:172205
|
|
decreased activity of thyroid gland |
J:172205
|
|
decreased circulating thyroxine level |
J:172205
|
|
enlarged thyroid gland |
J:172205
|
|
increased circulating thyroid-stimulating hormone level |
J:172205
|
|
increased thyroid carcinoma incidence |
J:172205
|
Braftm1Mmcm/Braftm1Mmcm
Cd207tm2.1(cre)Bjec/Cd207+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
increased dendritic cell number |
J:211690
|
|
liver inflammation |
J:211690
|
|
lung inflammation |
J:211690
|
Braftm1Mmcm/Braftm1Mmcm
Tg(Itgax-cre)1-1Reiz/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
|
anemia |
J:211690
|
|
cytokine storm |
J:211690
|
|
enlarged lymph nodes |
J:211690
|
|
granulomatous inflammation |
J:211690
|
|
hepatosplenomegaly |
J:211690
|
|
increased dendritic cell number |
J:211690
|
|
increased inflammatory response |
J:211690
|
|
premature death |
J:211690
|
Braftm1Mmcm/Braftm1Mmcm
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129P2/OlaHsd * FVB
|
abnormal melanocyte morphology |
J:151023
|
Braftm1Mmcm/?
Tg(TPO-cre)1Shk/0
involves: 129P2/OlaHsd * FVB/NCr
|
decreased birth weight |
J:172205
|
Braftm1Rima/Braf+
Tg(Tyr-cre/ERT2)1Lru/0
involves: C57BL/6 * DBA/2
|
normal
neoplasm |
J:161180
|
|
normal
pigmentation phenotype |
J:161180
|
Braftm1Sva/Braftm1.1Sva
Meox2tm1(cre)Sor/Meox2+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
|
lethality at weaning, complete penetrance |
J:105998
|
|
postnatal growth retardation |
J:105998
|
Braftm1Sva/Braftm1.1Sva
Tg(Nes-cre)1Kln/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
abnormal adenohypophysis morphology |
J:121660
|
|
abnormal body temperature homeostasis |
J:121660
|
|
abnormal growth hormone level |
J:121660
|
|
normal
behavior/neurological phenotype |
J:121660
|
|
decreased body weight |
J:121660
|
|
hyperactivity |
J:121660
|
|
hypoglycemia |
J:121660
|
|
lethality at weaning, incomplete penetrance |
J:121660
|
|
normal
nervous system phenotype |
J:121660
|
|
postnatal growth retardation |
J:121660
|
|
small adenohypophysis |
J:121660
|
|
thin cerebral cortex |
J:121660
|
Braftm1Sva/Braftm1Sva
Tg(Camk2a-cre)1557Sva/0
involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ * FVB
|
abnormal associative learning |
J:107042
|
|
abnormal spatial learning |
J:107042
|
|
reduced long-term potentiation |
J:107042
|
Braftm1Sva/Braftm1Sva
Tg(Tek-cre/ERT2)1Arnd/0
involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ
|
no abnormal phenotype detected |
J:105998
|
Braftm1Tumg/Braf+
Tg(CAG-cre)2Osb/0
involves: BALB/c * C57BL * C57BL/6J * DBA
|
enlarged heart |
J:226977
|
|
female infertility |
J:226977
|
|
hepatic necrosis |
J:226977
|
|
ostium secundum atrial septal defect |
J:226977
|
|
patent cardiac foramen ovale |
J:226977
|
|
postnatal growth retardation |
J:226977
|
|
postnatal lethality, incomplete penetrance |
J:226977
|
|
premature death |
J:226977
|
|
ruffled hair |
J:226977
|
|
sparse hair |
J:226977
|
Braftm1Tumg/Braf+
Tg(CAG-cre)2Osb/0
involves: C57BL * C57BL/6J * DBA
|
abnormal atrioventricular cushion morphology |
J:216228
|
|
abnormal coronary artery morphology |
J:216228
|
|
abnormal epicardium morphology |
J:216228
|
|
abnormal heart development |
J:216228
|
|
abnormal heart morphology |
J:216228
|
|
abnormal lymph organ development |
J:216228
|
|
abnormal myocardial trabeculae morphology |
J:216228
|
|
abnormal pulmonary valve cusp morphology |
J:216228
|
|
cyanosis |
J:216228
|
|
decreased liver weight |
J:216228
|
|
edema |
J:216228
|
|
enlarged heart |
J:216228
|
|
enlarged pulmonary valve |
J:216228
|
|
hemorrhage |
J:216228
|
|
hepatic necrosis |
J:216228
|
|
kyphosis |
J:216228
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:216228
|
|
mandible hypoplasia |
J:216228
|
|
mitral valve hypertrophy |
J:216228
|
|
neonatal lethality, complete penetrance |
J:216228
|
|
pulmonary alveolar hemorrhage |
J:216228
|
|
pulmonary valve hypertrophy |
J:216228
|
|
small liver |
J:216228
|
|
thick pulmonary valve |
J:216228
|
|
thick tricuspid valve |
J:216228
|
|
thin myocardium compact layer |
J:216228
|
|
tricuspid valve hypertrophy |
J:216228
|
|
ventricular septal defect |
J:216228
|
Braftm1Tumg/Braf+
Tg(CAG-cre)2Osb/0
involves: C57BL * C57BL/6J * DBA * ICR
|
abnormal locomotor behavior |
J:226977
|
|
abnormal myocardial fiber morphology |
J:226977
|
|
abnormal myocardial trabeculae morphology |
J:226977
|
|
atrial septal defect |
J:226977
|
|
decreased cranium length |
J:226977
|
|
decreased food intake |
J:226977
|
|
decreased vertical activity |
J:226977
|
|
female infertility |
J:226977
|
|
impaired contextual conditioning behavior |
J:226977
|
|
increased heart weight |
J:226977
|
|
kyphosis |
J:226977
|
|
long nails |
J:226977
|
|
nail dystrophy |
J:226977
|
|
ovary cyst |
J:226977
|
|
polydactyly |
J:226977
|
|
postnatal lethality, incomplete penetrance |
J:226977
|
|
pulmonary valve stenosis |
J:226977
|
|
round head |
J:226977
|
|
ruffled hair |
J:226977
|
|
slow postnatal weight gain |
J:226977
|
|
sparse hair |
J:226977
|
|
thick mitral valve cusps |
J:226977
|
|
thick pulmonary valve cusps |
J:226977
|
Braftm1Tumg/Braftm1Tumg
Tg(CAG-cre)2Osb/0
involves: C57BL * C57BL/6J * DBA * ICR
|
postnatal lethality, complete penetrance |
J:226977
|
Braftm1Wds/Braftm1.1Wds
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
|
abnormal adenohypophysis morphology |
J:121660
|
|
abnormal body temperature homeostasis |
J:121660
|
|
abnormal growth hormone level |
J:121660
|
|
normal
behavior/neurological phenotype |
J:121660
|
|
decreased body weight |
J:121660
|
|
hyperactivity |
J:121660
|
|
hypoglycemia |
J:121660
|
|
lethality at weaning, incomplete penetrance |
J:121660
|
|
normal
nervous system phenotype |
J:121660
|
|
postnatal growth retardation |
J:121660
|
|
small adenohypophysis |
J:121660
|
|
thin cerebral cortex |
J:121660
|
Braftm1Zim/Braftm1Zim
involves: 129
|
abnormal aorta morphology |
J:41257
|
|
abnormal apoptosis |
J:41257
|
|
abnormal blood vessel morphology |
J:41257
|
|
abnormal cardinal vein morphology |
J:41257
|
|
abnormal head morphology |
J:41257
|
|
abnormal neuron morphology |
J:41257
|
|
abnormal vascular endothelial cell morphology |
J:41257
|
|
abnormal vitelline vasculature morphology |
J:41257
|
|
decreased embryo weight |
J:41257
|
|
decreased heart rate |
J:41257
|
|
embryonic lethality during organogenesis, complete penetrance |
J:41257
|
|
hematoma |
J:41257
|
|
hemopericardium |
J:41257
|
|
hemorrhage |
J:41257
|
|
increased vascular endothelial cell number |
J:41257
|
|
intraventricular hemorrhage |
J:41257
|
|
poor circulation |
J:41257
|
Braftm1Zim/Braftm1Zim
involves: 129/Sv * C57BL/6 * CD-1
|
abnormal telencephalon development |
J:112971
|
|
embryonic lethality during organogenesis, complete penetrance |
J:112971
|
Braftm2.1Eyc/Braftm2.1Eyc
either: (involves: 129S2/SvPas * FVB/N ) or (involves: 129S2/SvPas * BALB/c * C57BL/6)
|
normal
behavior/neurological phenotype |
J:168330
|
|
impaired long-term object recognition memory |
J:168330
|
Braftm2.1Urr/Braftm2.1Urr
involves: 129 * C57BL/6 * FVB/N
|
no abnormal phenotype detected |
J:199842
|
Braftm2.1Urr/Braftm2.1Urr
Tg(Nes-cre)1Kln/0
involves: 129 * C57BL/6 * SJL
|
abnormal cerebellar molecular layer |
J:199842
|
|
abnormal cerebellum morphology |
J:199842
|
|
abnormal cerebellum vermis lobule I morphology |
J:199842
|
|
abnormal cerebellum vermis lobule II morphology |
J:199842
|
|
abnormal cerebellum vermis lobule III morphology |
J:199842
|
|
abnormal cerebellum vermis lobule morphology |
J:199842
|
|
abnormal cerebellum vermis lobule V morphology |
J:199842
|
|
abnormal cerebellum vermis lobule VII morphology |
J:199842
|
|
abnormal cerebellum vermis lobule X morphology |
J:199842
|
|
abnormal hippocampus granule cell layer |
J:199842
|
|
abnormal Purkinje cell dendrite morphology |
J:199842
|
|
abnormal Purkinje cell morphology |
J:199842
|
|
cerebellum hypoplasia |
J:199842
|
|
decreased body size |
J:199842
|
|
decreased body weight |
J:199842
|
|
decreased brain weight |
J:199842
|
|
decreased Purkinje cell number |
J:199842
|
|
impaired balance |
J:199842
|
|
impaired coordination |
J:199842
|
|
impaired neuron differentiation |
J:199842
|
|
increased aggression |
J:199842
|
|
increased neuronal precursor proliferation |
J:199842
|
|
postnatal lethality, incomplete penetrance |
J:199842
|
|
premature death |
J:199842
|
Braftm2.2Urr/Braftm2.2Urr
involves: 129 * C57BL/6 * FVB/N
|
decreased embryo size |
J:199842
|
|
embryonic growth retardation |
J:199842
|
|
embryonic lethality during organogenesis, complete penetrance |
J:199842
|
|
small placenta |
J:199842
|
Braftm2Cpri/Braf+
involves: C57BL/6
|
normal
cellular phenotype |
J:187371
|
|
normal
respiratory system phenotype |
J:187371
|
Braftm2Cpri/Braf+
Tg(CMV-cre)1Cgn/0
B6.Cg-Braftm2Cpri Tg(CMV-cre)1Cgn
|
abnormal eye morphology |
J:187371
|
|
abnormal facial morphology |
J:187371
|
|
abnormal myometrium morphology |
J:187371
|
|
cardiac hypertrophy |
J:187371
|
|
cataract |
J:187371
|
|
decreased body height |
J:187371
|
|
decreased body weight |
J:187371
|
|
enlarged heart |
J:187371
|
|
enlarged spleen |
J:187371
|
|
increased intestinal adenoma incidence |
J:187371
|
|
increased myocardial fiber size |
J:187371
|
|
increased skin papilloma incidence |
J:187371
|
|
increased spleen weight |
J:187371
|
|
increased susceptibility to ischemic brain injury |
J:187371
|
|
intestine polyps |
J:187371
|
|
long incisors |
J:187371
|
|
lymphoid hyperplasia |
J:187371
|
|
premature death |
J:187371
|
|
thick interventricular septum |
J:187371
|
|
thick ventricular wall |
J:187371
|
|
uterus prolapse |
J:187371
|
Braftm2Urr/Braftm2Urr
involves: 129 * C57BL/6
|
no abnormal phenotype detected |
J:199842
|
Braftm2Urr/Braftm2Urr
Tg(Nes-cre)1Kln/0
involves: 129 * C57BL/6 * SJL
|
abnormal cerebellar molecular layer |
J:199842
|
|
abnormal cerebellum morphology |
J:199842
|
|
abnormal cerebellum vermis lobule I morphology |
J:199842
|
|
abnormal cerebellum vermis lobule II morphology |
J:199842
|
|
abnormal cerebellum vermis lobule III morphology |
J:199842
|
|
abnormal cerebellum vermis lobule morphology |
J:199842
|
|
abnormal cerebellum vermis lobule V morphology |
J:199842
|
|
abnormal cerebellum vermis lobule VII morphology |
J:199842
|
|
abnormal cerebellum vermis lobule X morphology |
J:199842
|
|
abnormal hippocampus granule cell layer |
J:199842
|
|
abnormal neuronal precursor proliferation |
J:199842
|
|
abnormal Purkinje cell dendrite morphology |
J:199842
|
|
abnormal Purkinje cell morphology |
J:199842
|
|
cerebellum hypoplasia |
J:199842
|
|
decreased body size |
J:199842
|
|
decreased body weight |
J:199842
|
|
decreased brain weight |
J:199842
|
|
decreased Purkinje cell number |
J:199842
|
|
impaired balance |
J:199842
|
|
impaired coordination |
J:199842
|
|
impaired neuron differentiation |
J:199842
|
|
increased aggression |
J:199842
|
|
postnatal lethality, incomplete penetrance |
J:199842
|
|
premature death |
J:199842
|
Gt(ROSA)26Sortm11(CAG-Braf*/ERT2)Rkuhn/Gt(ROSA)26Sortm11(CAG-Braf*/ERT2)Rkuhn
involves: 129S6/SvEvTac * C57BL/6J
|
no abnormal phenotype detected |
J:196873
|
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