43 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Foxo1tm1Whb/Foxo1+ Pdpk1tm1Maka/Pdpk1tm1Maka Tg(Ins2-cre)23Herr/0 involves: 129S4/SvJae * C57BL/6J * CBA/J	abnormal pancreas physiology	J:109010
	decreased circulating glucose level	J:109010
	increased circulating insulin level	J:109010
	increased pancreatic beta cell number	J:109010
Gt(ROSA)26Sortm1(CAG-Foxo1*)Jcbr/Gt(ROSA)26Sor+ Pdpk1tm1Jcbr/Pdpk1tm1Jcbr Tg(Pomc1-cre)16Lowl/0 involves: C57BL/6 * FVB/N	decreased circulating corticosterone level	J:134336
	decreased corticotroph cell number	J:134336
	normal homeostasis/metabolism phenotype	J:134336
Gt(ROSA)26Sortm1(Foxo1)Jnk/Gt(ROSA)26Sor+ Pdpk1tm1Maka/Pdpk1tm1Maka Tg(CAG-cat,-lacZ)11Miya/0 Tg(Pomc1-cre)16Lowl/0 involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N	increased body weight	J:162892
Gt(ROSA)26Sortm2(Foxo1)Jnk/Gt(ROSA)26Sor+ Pdpk1tm1Maka/Pdpk1tm1Maka Tg(CAG-cat,-lacZ)11Miya/0 Tg(Pomc1-cre)16Lowl/0 involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N	increased body weight	J:162892
	increased food intake	J:162892
	increased total body fat amount	J:162892
Gt(ROSA)26Sortm2(Pik3ca*)Dsa/Gt(ROSA)26Sor+ Krastm4Tyj/Kras+ Pdpk1tm1Mlw/Pdpk1tm1Mlw Ptf1atm1(cre)Hnak/Ptf1a+ involves: 129S4/SvJae * 129S6/SvEvTac	normal endocrine/exocrine gland phenotype	J:197054
	normal neoplasm	J:197054
Gt(ROSA)26Sortm2(Pik3ca*)Dsa/Gt(ROSA)26Sor+ Pdpk1tm1Mlw/Pdpk1tm1Mlw Ptf1atm1(cre)Hnak/Ptf1a+ involves: 129S6/SvEvTac	normal endocrine/exocrine gland phenotype	J:197054
	normal neoplasm	J:197054
Krastm4Tyj/Kras+ Pdpk1tm1Mlw/Pdpk1tm1Mlw Ptf1atm1(cre)Hnak/Ptf1a+ involves: 129S4/SvJae	abnormal pancreas morphology	J:197054
	normal neoplasm	J:197054
Krastm4Tyj/Kras+ Pdpk1tm1Mlw/Pdpk1tm1Mlw Tg(Cela1-cre/ERT)1Dam/0 involves: 129S4/SvJae	increased lung non-small cell carcinoma incidence	J:197054
	normal neoplasm	J:197054
Pdpk1tm1.1Mlw/Pdpk1tm1.1Mlw Rag2tm1Fwa/Rag2tm1Fwa Tnfrsf4tm2(cre)Nik/Tnfrsf4+ Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ involves: 129S/SvEv * 129X1/SvJ * C57BL/6	abnormal keratinocyte differentiation	J:226194
	dermatitis	J:226194
	epidermal hyperplasia	J:226194
	premature death	J:226194
Pdpk1tm1.1Mlw/Pdpk1tm1.1Mlw Tnfrsf4tm2(cre)Nik/Tnfrsf4+ Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ involves: 129X1/SvJ * C57BL/6	abnormal hypodermis fat layer morphology	J:226194
	abnormal keratinocyte differentiation	J:226194
	abnormal regulatory T cell number	J:226194
	abnormal T cell physiology	J:226194
	cachexia	J:226194
	dermatitis	J:226194
	enlarged lymph nodes	J:226194
	enlarged spleen	J:226194
	epidermal hyperplasia	J:226194
	hair follicle degeneration	J:226194
	hyperkeratosis	J:226194
	impaired skin barrier function	J:226194
	premature death	J:226194
	premature hair loss	J:226194
	scaly skin	J:226194
	skin fibrosis	J:226194
	skin hyperplasia	J:226194
	skin lesions	J:226194
	thick skin	J:226194
Pdpk1tm1Bcol/Pdpk1tm1Bcol involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal craniofacial morphology	J:102388
	abnormal eye pigmentation	J:102388
	abnormal forelimb morphology	J:102388
	decreased embryo size	J:102388
	perinatal lethality, complete penetrance	J:102388
	short mandible	J:102388
Pdpk1tm1Maka/Pdpk1tm1Maka Ptentm1Hwu/Ptentm1Hwu Tg(Zp3-cre)93Knw/0 involves: 129S4/SvJae * C57BL/6J	normal reproductive system phenotype	J:165798
Pdpk1tm1Maka/Pdpk1tm1Maka Stat3tm2Aki/Stat3tm2Aki Tg(Alb1-cre)1Dlr/0 involves: 129S4/SvJae * 129P2/OlaHsd * FVB/N	abnormal glucose homeostasis	J:109359
	impaired glucose tolerance	J:109359
Pdpk1tm1Maka/Pdpk1tm1Maka Tsc1tm1Djk/Tsc1tm1Djk Tg(Gdf9-icre)5092Coo/? involves: 129S4/SvJae * C57BL/6J	abnormal ovarian follicle morphology	J:155357