Apptm1.1Cep/Apptm1.1Cep
Psen1tm1Dgf/Psen1tm1Dgf
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
amyloid beta deposits |
J:66147,
J:102425
|
Apptm1Ck/Apptm1Ck
Psen1tm1Mpm/Psen1tm1Mpm
involves: 129 * 129S1/Sv * 129X1/SvJ
|
abnormal brain morphology |
J:191170
|
|
abnormal spatial working memory |
J:191170
|
|
amyloid beta deposits |
J:166379
|
|
enhanced contextual conditioning behavior |
J:191170
|
|
increased anxiety-related response |
J:191170
|
|
increased circulating corticosterone level |
J:191170
|
Apptm1Ck/Apptm1Ck
Psen1tm1Mpm/Psen1tm1Mpm
Tg(MAPT)8cPdav/0
B6.Cg-Tg(MAPT)8cPdav Psen1tm1Mpm Apptm1Ck
|
amyloid beta deposits |
J:209782
|
|
decreased locomotor activity |
J:209782
|
|
enhanced contextual conditioning behavior |
J:209782
|
|
increased anxiety-related response |
J:209782
|
|
increased fear-related response |
J:209782
|
|
tau protein deposits |
J:209782
|
Apptm3.1Zhe/Apptm3.1Zhe
Psen1tm1Mpm/Psen1tm1Mpm
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
|
amyloid beta deposits |
J:166379
|
Cx3cr1tm1Litt/Cx3cr1+
Psen1tm1Mpm/Psen1tm1Mpm
Tg(APPSwe,tauP301L)1Lfa/0
Tg(Thy1-YFP)HJrs/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal microglial cell morphology |
J:159680
|
|
abnormal microglial cell physiology |
J:159680
|
|
neuron degeneration |
J:159680
|
Cx3cr1tm1Litt/Cx3cr1tm1Litt
Psen1tm1Mpm/Psen1tm1Mpm
Tg(APPSwe,tauP301L)1Lfa/0
Tg(Thy1-YFP)HJrs/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
normal
nervous system phenotype |
J:159680
|
Mesp2tm4Ysa/Mesp2tm4Ysa
Psen1tm1Shs/Psen1tm1Shs
involves: C57BL/6 * CBA
|
abnormal vertebral arch morphology |
J:78989
|
Mesp2tm5(Notch1)Ysa/Mesp2tm5(Notch1)Ysa
Psen1tm1Shs/Psen1tm1Shs
involves: C57BL/6 * CBA
|
abnormal vertebral arch morphology |
J:78989
|
Psen1tm1.1Ruvi/Psen1tm1.1Ruvi
Tg(APP)8.9Btla/0
involves: 129S2/SvPas * C57BL/6J
|
amyloid beta deposits |
J:187475
|
|
astrocytosis |
J:187475
|
|
microgliosis |
J:187475
|
|
neurodegeneration |
J:187475
|
Psen1tm1.1Tcs/Psen1tm1.1Tcs
Tg(APPSWE)2576Kha/0
involves: C57BL/6 * C57BL/6J * SJL
|
abnormal short-term spatial reference memory |
J:175901
|
|
amyloid beta deposits |
J:175901
|
|
astrocytosis |
J:175901
|
Psen1tm1Bdes/Psen1+
Psen2tm1Bdes/Psen2tm1Bdes
involves: 129P2/OlaHsd
|
abnormal corneal epithelium morphology |
J:91235
|
|
abnormal epidermal layer morphology |
J:91235
|
|
abnormal skin condition |
J:91235
|
|
abnormal T cell subpopulation ratio |
J:91235
|
|
arteritis |
J:91235
|
|
autoimmune response |
J:91235
|
|
chronic inflammation |
J:91235
|
|
dermatitis |
J:91235
|
|
enlarged lymph nodes |
J:91235
|
|
enlarged spleen |
J:91235
|
|
epidermal cyst |
J:91235
|
|
epidermal hyperplasia |
J:91235
|
|
glomerulonephritis |
J:91235
|
|
hematuria |
J:91235
|
|
hyperkeratosis |
J:91235
|
|
increased anti-single stranded DNA antibody level |
J:91235
|
|
increased immunoglobulin level |
J:91235
|
|
increased incidence of corneal inflammation |
J:91235
|
|
increased inflammatory response |
J:91235
|
|
increased leukocyte cell number |
J:91235
|
|
increased susceptibility to autoimmune disorder |
J:91235
|
|
increased urine protein level |
J:91235
|
|
kidney inflammation |
J:91235
|
|
skin inflammation |
J:91235
|
|
skin lesions |
J:91235
|
|
spontaneous skin ulceration |
J:91235
|
Psen1tm1Bdes/Psen1tm1Bdes
Psen2tm1Bdes/Psen2tm1Bdes
involves: 129P2/OlaHsd * C57BL/6J
|
abnormal blood circulation |
J:58118
|
|
abnormal brain development |
J:58118
|
|
abnormal forebrain development |
J:58118
|
|
abnormal hindbrain development |
J:58118
|
|
abnormal visceral yolk sac morphology |
J:58118
|
|
abnormal vitelline vascular remodeling |
J:58118
|
|
abnormal vitelline vasculature morphology |
J:58118
|
|
caudal body truncation |
J:58118
|
|
distended pericardium |
J:58118
|
|
embryonic growth retardation |
J:58118
|
|
kinked neural tube |
J:58118
|
|
prenatal lethality, complete penetrance |
J:58118
|
Psen1tm1Dgf/Psen1+
Tg(APPSWE)2576Kha/0
involves: 129S1/Sv * 129X1/SvJ * CD-1 * C57BL/6 * SJL
|
amyloid beta deposits |
J:66147
|
|
gliosis |
J:66147
|
Psen1tm1Dgf/Psen1tm1Dgf
Tg(APPSWE)2576Kha/?
involves: 129 * C57BL/6 * CD-1 * SJL
|
amyloid beta deposits |
J:102425
|
Psen1tm1Jzt/Psen1tm1Jzt
Psen2tm1Ber/Psen2tm1Ber
Tg(Camk2a-cre)T29-1Stl/0
involves: C57BL/6 * CBA
|
abnormal apoptosis |
J:90685
|
|
abnormal cerebral cortex morphology |
J:90685
|
|
abnormal corpus callosum morphology |
J:90685
|
|
abnormal hippocampus molecular cell layer |
J:90685
|
|
abnormal neuron morphology |
J:90685
|
|
abnormal object recognition memory |
J:90685
|
|
enlarged lateral ventricles |
J:90685
|
|
enlarged third ventricle |
J:90685
|
|
gliosis |
J:90685
|
|
hyperactivity |
J:90685
|
|
neurodegeneration |
J:90685
|
|
weight loss |
J:90685
|
Psen1tm1Lpr/Psen1tm1Lpr
Tg(Thy1-APPSL)28Lpr/0
either: 129/Sv or (involves: 129/Sv * C57BL/6)
|
abnormal hippocampus pyramidal cell layer |
J:93770
|
|
amyloid beta deposits |
J:93770
|
Psen1tm1Lpr/Psen1tm1Lpr
Tg(Thy1-APPSL)28Lpr/0
involves: 129 * C57BL/6 * CBA
|
abnormal axon morphology |
J:128106
|
|
abnormal dentate gyrus morphology |
J:139736
|
|
abnormal frontal lobe morphology |
J:146342
|
|
abnormal hippocampus granule cell morphology |
J:139736
|
|
abnormal hippocampus morphology |
J:139736
|
|
abnormal myelin sheath morphology |
J:128106
|
|
abnormal neurite morphology |
J:128106
|
|
abnormal thalamus morphology |
J:146342
|
|
amyloid beta deposits |
J:128106,
J:128243,
J:139736,
J:146342
|
|
decreased body weight |
J:128106
|
|
decreased circulating cholesterol level |
J:128243
|
|
decreased neuron number |
J:146342
|
|
impaired coordination |
J:128106
|
|
increased circulating cholesterol level |
J:128243
|
|
limb grasping |
J:128106
|
Psen1tm1Mpm/Psen1tm1Mpm
Tg(APPSWE)2576Kha/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
amyloid beta deposits |
J:175901
|
Psen1tm1Mpm/Psen1tm1Mpm
Tg(APPSwe,tauP301L)1Lfa/?
B6.Cg-Psen1tm1Mpm Tg(APPSwe,tauP301L)1Lfa
|
abnormal behavior |
J:170670
|
Psen1tm1Mpm/Psen1tm1Mpm
Tg(APPSwe,tauP301L)1Lfa/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
amyloid beta deposits |
J:107286
|
|
neurofibrillary tangles |
J:107286
|
Psen1tm1Mpm/Psen1tm1Mpm
Tg(APPSwe,tauP301L)1Lfa/Tg(APPSwe,tauP301L)1Lfa
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal contextual conditioning behavior |
J:99604
|
|
abnormal learning/memory/conditioning |
J:99604
|
|
amyloid beta deposits |
J:99604
|
Psen1tm1Pcw/Psen1+
Psen2tm1Ber/Psen2+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
|
no abnormal phenotype detected |
J:58465
|
Psen1tm1Pcw/Psen1+
Psen2tm1Ber/Psen2tm1Ber
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
|
no abnormal phenotype detected |
J:58465
|
Psen1tm1Pcw/Psen1tm1Pcw
Psen2tm1Ber/Psen2+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
|
abnormal heart looping |
J:58465
|
|
abnormal neural tube morphology |
J:58465
|
|
delayed neural tube closure |
J:58465
|
|
embryonic lethality during organogenesis, complete penetrance |
J:58465
|
|
failure of somite differentiation |
J:58465
|
|
small heart |
J:58465
|
|
small second pharyngeal arch |
J:58465
|
Psen1tm1Pcw/Psen1tm1Pcw
Psen2tm1Ber/Psen2tm1Ber
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J
|
abnormal chorioallantoic fusion |
J:58465
|
|
abnormal forebrain morphology |
J:58465
|
|
abnormal midbrain development |
J:58465
|
|
abnormal neural tube morphology |
J:58465
|
|
abnormal paraxial mesoderm morphology |
J:58465
|
|
abnormal somite development |
J:58465
|
|
delayed neural tube closure |
J:58465
|
|
embryonic lethality during organogenesis, complete penetrance |
J:58465
|
|
failure of heart looping |
J:58465
|
|
kinked neural tube |
J:58465
|
|
small heart |
J:58465
|
|
small second pharyngeal arch |
J:58465
|
Psen1tm1Vln/Psen1tm1Vln
Tg(Thy1-APPLon)2Vln/0
Tg(Thy1-cre)1Vln/0
involves: FVB/N
|
abnormal long-term potentiation |
J:87229
|
|
abnormal object recognition memory |
J:87229
|
|
normal
nervous system phenotype |
J:87229
|
Psen1tm1Zhe/Psen1tm1Zhe
Tg(APPSWE)2576Kha/?
involves: 129S7/SvEvBrd * C57BL/6 * SJL
|
amyloid beta deposits |
J:107251
|
Psen1tm2Psgh/Psen1tm2Psgh
involves: 129S1/Sv * 129X1/SvJ
|
abnormal axial skeleton morphology |
J:80624
|
|
abnormal forebrain morphology |
J:80624
|
|
abnormal spinal cord morphology |
J:80624
|
|
abnormal vertebrae morphology |
J:80624
|
|
abnormal vertebral body morphology |
J:80624
|
|
abnormal vertebral column morphology |
J:80624
|
|
abnormal vertebral lamina morphology |
J:80624
|
|
decreased body size |
J:80624
|
|
hindlimb paralysis |
J:80624
|
|
intracranial hemorrhage |
J:80624
|
|
kinked tail |
J:80624
|
|
normal
nervous system phenotype |
J:80624
|
|
postnatal lethality, incomplete penetrance |
J:80624
|
|
premature death |
J:80624
|
|
prenatal lethality, incomplete penetrance |
J:80624
|
|
short tail |
J:80624
|
|
spinal hemorrhage |
J:80624
|
Psen1tm2Shn/Psen1tm2Shn
Psen2tm1Haa/Psen2+
Tg(Msx2-cre)5Rem/0
involves: 129S4/SvJae
|
abnormal hair follicle morphology |
J:94517
|
Psen1tm2Shn/Psen1tm2Shn
Psen2tm1Haa/Psen2tm1Haa
Tg(Msx2-cre)5Rem/0
involves: 129S4/SvJae * C57BL/6 * CBA
|
abnormal hair follicle inner root sheath morphology |
J:94517
|
|
abnormal hair follicle morphology |
J:94517
|
|
abnormal hair growth |
J:94517
|
|
absent sebocyte |
J:94517
|
|
decreased body size |
J:94517
|
|
epidermal cyst |
J:94517
|
|
epidermal hyperplasia |
J:94517
|
|
esophagus hyperplasia |
J:94517
|
|
focal hair loss |
J:94517
|
|
hair follicle degeneration |
J:94517
|
|
premature death |
J:94517
|
|
scaly skin |
J:94517
|
|
short hair |
J:94517
|
|
thick epidermis |
J:94517
|
|
thick skin |
J:94517
|
Psen1tm2Shn/Psen1tm4.1Shn
Psen2tm1Haa/Psen2tm1Haa
Tg(Camk2a-cre)1Shn/0
involves: 129 * 129S4/SvJae * C57BL/6 * C57BL/6J * CBA
|
abnormal cerebral cortex morphology |
J:219929
|
|
abnormal neocortex morphology |
J:219929
|
|
astrocytosis |
J:219929
|
|
decreased neuron number |
J:219929
|
|
microgliosis |
J:219929
|
|
neurodegeneration |
J:219929
|
Psen1tm3.1Shn/Psen1tm3.1Shn
Psen2tm1Haa/Psen2tm1Haa
involves: 129 * C57BL/6 * C57BL/6J * CBA
|
abnormal spatial working memory |
J:184454
|
Psen1tm4.1Shn/Psen1+
Psen2tm1Haa/Psen2tm1Haa
involves: 129 * C57BL/6 * C57BL/6J
|
abnormal spatial reference memory |
J:219929
|
|
decreased paired-pulse facilitation |
J:219929
|
|
impaired synaptic plasticity |
J:219929
|
|
increased synaptic depression |
J:219929
|
|
reduced long-term potentiation |
J:219929
|
Psen1tm4.1Shn/Psen1+
Tg(PDGFB-APP)5Lms/0
involves: 129 * C57BL/6 * C57BL/6J * DBA/2
|
normal
nervous system phenotype |
J:219929
|
Psen1tm4.1Shn/Psen1+
Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129 * C57BL/6 * C57BL/6J * DBA/2
|
amyloid beta deposits |
J:219929
|
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