Cdc42Gt(Ex160)Byg/Cdc42Gt(Ex160)Byg
involves: 129P2/OlaHsd * C57BL/6
|
embryonic lethality between implantation and somite formation, complete penetrance |
J:70273
|
Cdc42tm1.1Ayam/Cdc42tm1.1Ayam Tg(Mpz-cre)94Imeg/0
Not Specified
|
abnormal craniofacial bone morphology |
J:250065
|
abnormal frontal bone morphology |
J:250065
|
abnormal mandible morphology |
J:250065
|
abnormal medial nasal prominence morphology |
J:250065
|
abnormal nasal bone morphology |
J:250065
|
abnormal nasal septum morphology |
J:250065
|
abnormal premaxilla morphology |
J:250065
|
abnormal secondary palate development |
J:250065
|
absent gastric milk in neonates |
J:250065
|
absent palatal shelf |
J:250065
|
cleft palate |
J:250065
|
facial cleft |
J:250065
|
failure of palatal shelf elevation |
J:250065
|
intracranial hemorrhage |
J:250065
|
maxillary shelf hypoplasia |
J:250065
|
neonatal lethality, incomplete penetrance |
J:250065
|
palatine bone horizontal plate hypoplasia |
J:250065
|
short maxilla |
J:250065
|
short premaxilla |
J:250065
|
short snout |
J:250065
|
Cdc42tm1.1Ayam/Cdc42tm1.1Ayam Tg(Prrx1-cre)1Cjt/0
involves: 129P2/OlaHsd * C57BL/6 * ICR * SJL
|
abnormal autopod joint morphology |
J:184022
|
abnormal autopod morphology |
J:184022
|
abnormal cartilage development |
J:184022
|
abnormal interdigital cell death |
J:184022
|
abnormal intramembranous bone ossification |
J:184022
|
abnormal joint morphology |
J:184022
|
abnormal limb bone morphology |
J:184022
|
abnormal limb morphology |
J:184022
|
abnormal long bone epiphyseal plate morphology |
J:184022
|
abnormal palatal shelf morphology |
J:184022
|
abnormal suckling behavior |
J:184022
|
abnormal xiphoid process morphology |
J:184022
|
brachydactyly |
J:184022
|
cleft palate |
J:184022
|
decreased birth body size |
J:184022
|
decreased body length |
J:184022
|
delayed fontanelle closure |
J:184022
|
disorganized long bone epiphyseal plate |
J:184022
|
fused metacarpal bones |
J:184022
|
fused phalanges |
J:184022
|
increased width of hypertrophic chondrocyte zone |
J:184022
|
interdigital webbing |
J:184022
|
neonatal lethality, incomplete penetrance |
J:184022
|
postnatal lethality, incomplete penetrance |
J:184022
|
short limbs |
J:184022
|
split sternum |
J:184022
|
syndactyly |
J:184022
|
weakness |
J:184022
|
Cdc42tm1.1Rac/Cdc42tm1.1Rac
involves: 129P2/OlaHsd * FVB/N
|
no abnormal phenotype detected |
J:197886
|
Cdc42tm1.1Rac/Cdc42tm1.1Rac Tg(GFAP-cre)25Mes/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal brain ependyma morphology |
J:197886
|
abnormal brain ventricle morphology |
J:197886
|
absent brain ependyma motile cilia |
J:197886
|
domed cranium |
J:197886
|
enlarged lateral ventricles |
J:197886
|
enlarged third ventricle |
J:197886
|
hydrocephaly |
J:197886
|
premature death |
J:197886
|
thin cerebral cortex |
J:197886
|
Cdc42tm1.1Rac/Cdc42tm1.1Rac Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
|
abnormal brain ependyma morphology |
J:197886
|
abnormal cell nucleus morphology |
J:197886
|
abnormal cerebral aqueduct morphology |
J:197886
|
abnormal cerebral cortex morphology |
J:197886
|
abnormal cortical plate morphology |
J:197886
|
abnormal cortical ventricular zone morphology |
J:197886
|
abnormal glial cell morphology |
J:197886
|
abnormal lateral ventricle morphology |
J:197886
|
abnormal neocortex morphology |
J:197886
|
abnormal neuronal precursor proliferation |
J:197886
|
abnormal spinal cord central canal morphology |
J:197886
|
abnormal third ventricle morphology |
J:197886
|
absent gastric milk in neonates |
J:197886
|
cerebral aqueductal stenosis |
J:197886
|
decreased locomotor activity |
J:197886
|
decreased neuronal precursor cell number |
J:197886
|
enlarged brain ventricles |
J:197886
|
intraventricular hemorrhage |
J:197886
|
postnatal lethality, complete penetrance |
J:197886
|
respiratory distress |
J:197886
|
small olfactory bulb |
J:197886
|
thin cerebral cortex |
J:197886
|
Cdc42tm1.1Yizh/Cdc42+
Not Specified
|
decreased ventricle muscle contractility |
J:174208
|
Cdc42tm1b(EUCOMM)Hmgu/Cdc42+
C57BL/6N-Cdc42tm1b(EUCOMM)Hmgu/H
|
abnormal cranium morphology |
J:211773
|
abnormal retina morphology |
J:211773
|
decreased circulating serum albumin level |
J:211773
|
enlarged kidney |
J:211773
|
increased circulating alkaline phosphatase level |
J:211773
|
increased circulating aspartate transaminase level |
J:211773
|
increased circulating cholesterol level |
J:211773
|
increased circulating HDL cholesterol level |
J:211773
|
Cdc42tm1b(EUCOMM)Hmgu/Cdc42tm1b(EUCOMM)Hmgu
C57BL/6N-Cdc42tm1b(EUCOMM)Hmgu/H
|
embryonic lethality prior to organogenesis |
J:211773
|
embryonic lethality prior to tooth bud stage |
J:211773
|
preweaning lethality, complete penetrance |
J:211773
|
Cdc42tm1Brak/Cdc42tm1Brak Lgr5tm1(cre/ERT2)Cle/Lgr5+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal crypts of Lieberkuhn morphology |
J:184563
|
absent Paneth cells |
J:184563
|
Cdc42tm1Brak/Cdc42tm1Brak Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
involves: 129 * C57BL/6J
|
abnormal kidney cortex morphology |
J:195266
|
abnormal kidney development |
J:195266
|
abnormal kidney papilla morphology |
J:195266
|
abnormal nephrogenic zone morphology |
J:195266
|
abnormal proximal convoluted tubule morphology |
J:195266
|
anuria |
J:195266
|
decreased renal glomerulus number |
J:195266
|
decreased renal tubule number |
J:195266
|
postnatal lethality, complete penetrance |
J:195266
|
renal hypoplasia |
J:195266
|
Cdc42tm1Brak/Cdc42tm1Brak Tg(KRT5-cre)5132Jlj/0
involves: C57BL/6J * DBA/2J
|
abnormal epidermal layer morphology |
J:105811
|
abnormal epidermis stratum corneum morphology |
J:105811
|
abnormal hair follicle matrix region morphology |
J:105811
|
abnormal hair follicle morphology |
J:105811
|
abnormal hair shaft morphology |
J:105811
|
abnormal keratinocyte morphology |
J:105811
|
absent hair follicle inner root sheath |
J:105811
|
dermal cyst |
J:105811
|
epidermal hyperplasia |
J:105811
|
hyperkeratosis |
J:105811
|
postnatal growth retardation |
J:105811
|
Cdc42tm1Brak/Cdc42tm1Brak Tg(Pax8-rtTA2S*M2)1Koes/0 Tg(tetO-cre)LC1Bjd/0
involves: BALB/c * C57BL/6 * DBA
|
abnormal renal tubule epithelium morphology |
J:221423
|
increased susceptibility to kidney reperfusion injury |
J:221423
|
Cdc42tm1Brak/Cdc42tm1Brak Tg(Pf4-icre)Q3Rsko/0
involves: 129 * C57BL/6
|
abnormal platelet activation |
J:160792
|
abnormal platelet dense granule physiology |
J:160792
|
abnormal platelet morphology |
J:160792
|
abnormal platelet physiology |
J:160792
|
increased bleeding time |
J:160792
|
increased platelet aggregation |
J:160792
|
increased susceptibility to induced thrombosis |
J:160792
|
thrombocytopenia |
J:160792
|
Cdc42tm1Brak/Cdc42tm1Brak Tg(Plp1-cre/ERT2)1Ueli/0
involves: C57BL/6 * DBA/2
|
abnormal myelin sheath morphology |
J:190437
|
Cdc42tm1Brak/Cdc42tm1Brak Tg(Vil1-cre)997Gum/0
involves: C57BL/6J * SJL
|
abnormal anus morphology |
J:184563
|
abnormal crypts of Lieberkuhn morphology |
J:184563
|
abnormal defecation |
J:184563
|
abnormal enterocyte morphology |
J:184563
|
abnormal intestinal enteroendocrine cell morphology |
J:184563
|
abnormal intestinal epithelium morphology |
J:184563
|
abnormal intestinal goblet cell morphology |
J:184563
|
abnormal intestine morphology |
J:184563
|
abnormal intestine physiology |
J:184563
|
abnormal small intestinal crypt cell physiology |
J:184563
|
decreased body size |
J:184563
|
decreased Paneth cell number |
J:184563
|
increased small intestinal crypt cell apoptosis |
J:184563
|
intestinal edema |
J:184563
|
postnatal growth retardation |
J:184563
|
premature death |
J:184563
|
Cdc42tm1Fwa/Cdc42tm1Fwa
involves: 129S6/SvEvTac
|
abnormal actin cytoskeleton morphology |
J:63261
|
absent embryonic epiblast |
J:63261
|
decreased embryo size |
J:63261
|
disorganized embryonic tissue |
J:63261
|
embryonic lethality between implantation and somite formation, complete penetrance |
J:63261
|
Cdc42tm1Yizh/Cdc42tm1Yizh Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd
|
abnormal embryonic neuroepithelium morphology |
J:116100
|
abnormal eye development |
J:116100
|
abnormal folding of telencephalic vesicles |
J:116100
|
abnormal telencephalon development |
J:116100
|
holoprosencephaly |
J:116100
|
lethality throughout fetal growth and development, complete penetrance |
J:116100
|
small embryonic telencephalon |
J:116100
|