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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rbl1
RB transcriptional corepressor like 1
MGI:103300
107 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
E2f1tm1Meg/E2f1+
Rbl1tm1Htr/Rbl1tm1Htr
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129 * C57BL/6 * FVB/N * NMRI 		abnormal eye development J:124204
E2f1tm1Meg/E2f1tm1Meg
E2f3tm1.1Gle/E2f3tm1.1Gle
Rbl1tm1Htr/Rbl1tm1Htr
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129 * C57BL/6 * FVB/N * NMRI 		normal vision/eye phenotype J:124204
E2f1tm1Meg/E2f1tm1Meg
Rbl1tm1Htr/Rbl1tm1Htr
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129 * C57BL/6 * FVB/N * NMRI 		abnormal amacrine cell morphology J:124204
abnormal cone electrophysiology J:124204
abnormal retina bipolar cell morphology J:124204
abnormal retina inner plexiform layer morphology J:124204
abnormal retina morphology J:124204
decreased retina ganglion cell number J:124204
thin retina outer nuclear layer J:124204
E2f2tm1Zubi/E2f2tm1Zubi
Rbl1tm1Htr/Rbl1tm1Htr
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129 * C57BL/6 * FVB/N * NMRI 		abnormal eye development J:124204
abnormal retina bipolar cell morphology J:124204
decreased retina ganglion cell number J:124204
decreased retina rod cell number J:124204
E2f3tm1.1Gle/E2f3tm1.1Gle
Rbl1tm1Htr/Rbl1tm1Htr
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129 * C57BL/6 * FVB/N * NMRI 		abnormal amacrine cell morphology J:124204
abnormal eye development J:124204
abnormal retina bipolar cell morphology J:124204
decreased retina ganglion cell number J:124204
decreased retina rod cell number J:124204
Rb1tm1Tyj/Rb1+
Rbl1tm1Tyj/Rbl1+
involves: 129S2/SvPas * C57BL/6 		decreased tumor-free survival time J:34058
increased pituitary gland tumor incidence J:34058
Rb1tm1Tyj/Rb1+
Rbl1tm1Tyj/Rbl1tm1Tyj
involves: 129S2/SvPas * C57BL/6 		abnormal perineum morphology J:34058
abnormal retina morphology J:34058
abnormal retina photoreceptor morphology J:34058
decreased body size J:34058
decreased body weight J:34058
decreased tumor-free survival time J:34058
distended abdomen J:34058
increased pituitary gland tumor incidence J:34058
postnatal growth retardation J:34058
postnatal lethality, incomplete penetrance J:34058
premature death J:34058
vagina atresia J:34058
Rb1tm1Tyj/Rb1tm1Tyj
Rbl1tm1Mru/Rbl1tm1Mru
involves: 129S2/SvPas * 129S4/SvJae * BALB/c * C57BL/6 		increased neuronal precursor cell number J:92520
Rb1tm1Tyj/Rb1tm1Tyj
Rbl1tm1Tyj/Rbl1tm1Tyj
involves: 129S2/SvPas * C57BL/6 		abnormal vitelline vasculature morphology J:34058
decreased embryo size J:34058
embryonic lethality during organogenesis, incomplete penetrance J:34058
increased apoptosis J:34058
normal muscle phenotype J:34058
pale yolk sac J:34058
Rb1tm1Tyj/Rb1tm2Brn
Rbl1tm1Tyj/Rbl1+
Trp53tm1Brn/Trp53tm1Brn
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL 		abnormal retina morphology J:120315
increased retinoblastoma incidence J:120315
Rb1tm1Tyj/Rb1tm2Brn
Rbl1tm1Tyj/Rbl1+
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL 		abnormal eye posterior chamber morphology J:120315
abnormal retina morphology J:120315
decreased retina photoreceptor cell number J:120315
increased retinoblastoma incidence J:120315
Rb1tm1Tyj/Rb1tm2Brn
Rbl1tm1Tyj/Rbl1tm1Tyj
Trp53tm1Brn/Trp53tm1Brn
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL 		abnormal eye anterior chamber morphology J:120315
abnormal eye posterior chamber morphology J:120315
abnormal retina morphology J:120315
increased retinoblastoma incidence J:120315
Rb1tm1Tyj/Rb1tm2Brn
Rbl1tm1Tyj/Rbl1tm1Tyj
Trp53tm1Brn/Trp53tm1Tyj
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL 		abnormal cell proliferation J:120315
abnormal eye anterior chamber morphology J:120315
abnormal eye posterior chamber morphology J:120315
increased retinoblastoma incidence J:120315
Rb1tm2Brn/Rb1tm2Brn
Rbl1tm1Htr/Rbl1+
Trp53tm1Brn/Trp53tm1Brn
Tg(En2-cre)22Alj/0
involves: 129P2/OlaHsd * CD-1 		normal cellular phenotype J:83783
Rb1tm2Brn/Rb1tm2Brn
Rbl1tm1Htr/Rbl1+
Tg(En2-cre)22Alj/0
involves: 129P2/OlaHsd * CD-1 		abnormal cerebellum vermis morphology J:83783
abnormal neuronal precursor proliferation J:83783
ataxia J:83783
cerebellum hypoplasia J:83783
increased neuron apoptosis J:83783
Rb1tm2Brn/Rb1tm2Brn
Rbl1tm1Htr/Rbl1tm1Htr
Tg(En2-cre)22Alj/0
involves: 129P2/OlaHsd * CD-1 		abnormal cerebellar cortex morphology J:83783
abnormal cerebellum vermis morphology J:83783
abnormal neuronal precursor proliferation J:83783
abnormal Purkinje cell morphology J:83783
ataxia J:83783
thin cerebellar molecular layer J:83783
Rb1tm2Brn/Rb1tm2Brn
Rbl1tm1Htr/Rbl1tm1Htr
Tg(Pcp2-cre)756Mro/0
involves: 129P2/OlaHsd * FVB 		abnormal Purkinje cell morphology J:83783
Rb1tm2Brn/Rb1tm2Brn
Rbl1tm1Tyj/Rbl1tm1Tyj
Rbl2tm2Tyj/Rbl2tm2Tyj
involves: 129 * 129S2/SvPas * 129S4/SvJae 		hematuria J:217195
increased urinary bladder carcinoma incidence J:217195
Rb1tm3Tyj/Rb1tm3Tyj
Rbl1tm1Tyj/Rbl1tm1Tyj
Rbl2tm2.1Tyj/Rbl2tm2.1Tyj
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		increased hepatocellular carcinoma incidence J:177573
Rb1tm3Tyj/Rb1tm3Tyj
Rbl1tm1Tyj/Rbl1tm1Tyj
Tg(Nes-cre)1Atp/0
involves: 129S2/SvPas * 129S4/SvJae * FVB/N 		abnormal retina apoptosis J:91406
abnormal retina morphology J:91406
postnatal lethality J:91406
Rb1tm3Tyj/Rb1tm3Tyj
Rbl1tm1Tyj/Rbl1tm1Tyj
Tg(Pax6-cre,GFP)2Pgr/0
involves: 129S2/SvPas * 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB/N 		abnormal retina morphology J:119919
increased retinoblastoma incidence J:119919
Rbl1tm1.1Fad/Rbl1tm1.1Fad
Rbl2tm1Tyj/Rbl2tm1Tyj
involves: 129S2/SvPas * C57BL/6 * FVB/N 		abnormal bone mineralization J:217445
abnormal long bone epiphyseal ossification zone morphology J:217445
abnormal long bone epiphyseal plate proliferative zone J:217445
abnormal middle ear ossicle morphology J:217445
abnormal scapular spine morphology J:217445
normal cellular phenotype J:217445
decreased body size J:217445
decreased length of long bones J:217445
decreased long bone epiphyseal plate size J:217445
interparietal bone hypoplasia J:217445
neonatal lethality, incomplete penetrance J:217445
postnatal lethality, complete penetrance J:217445
short femur J:217445
short fibula J:217445
short radius J:217445
short tibia J:217445
short ulna J:217445
small supraoccipital bone J:217445
Rbl1tm1Tyj/Rbl1+
Rbl2tm1Tyj/Rbl2tm1Tyj
involves: 129S2/SvPas * C57BL/6 		normal limbs/digits/tail phenotype J:34725
postnatal growth retardation J:34725
Rbl1tm1Tyj/Rbl1tm1Tyj
Rbl2tm1Tyj/Rbl2+
involves: 129S2/SvPas * C57BL/6 		abnormal forelimb morphology J:34725
decreased body weight J:34725
delayed fertility J:34725
distended abdomen J:34725
postnatal lethality, incomplete penetrance J:34725
reduced female fertility J:34725
short forelimb J:34725
short limbs J:34725
short snout J:34725
Rbl1tm1Tyj/Rbl1tm1Tyj
Rbl2tm1Tyj/Rbl2tm1Tyj
involves: 129S2/SvPas * C57BL/6 		abnormal awl hair morphology J:82802
abnormal breathing pattern J:34725
abnormal chondrocyte morphology J:34725
abnormal craniofacial bone morphology J:34725
abnormal epidermis stratum granulosum morphology J:82802
abnormal forelimb morphology J:34725
abnormal guard hair morphology J:82802
abnormal hair cycle J:82802
abnormal hair follicle development J:82802
abnormal hair follicle orientation J:82802
abnormal humerus morphology J:34725
abnormal keratinocyte differentiation J:82802
abnormal limb bone morphology J:34725
abnormal long bone epiphyseal plate morphology J:34725
abnormal long bone epiphyseal plate proliferative zone J:34725
abnormal rib development J:34725
abnormal supraoccipital bone morphology J:34725
abnormal tooth development J:82802
abnormal tracheal cartilage morphology J:34725
abnormal zigzag hair morphology J:82802
absent incisors J:82802
apnea J:34725
decreased body size J:34725
decreased fetal size J:34725
decreased hair follicle number J:82802
delayed emergence of vibrissae J:82802
delayed endochondral bone ossification J:34725
distended abdomen J:34725
enlarged sebaceous gland J:82802
epidermal hyperplasia J:82802
increased diameter of humerus J:34725
increased diameter of radius J:34725
increased diameter of ulna J:34725
increased width of hypertrophic chondrocyte zone J:34725
interparietal bone hypoplasia J:34725
neonatal lethality, complete penetrance J:34725
parakeratosis J:82802
perinatal lethality, incomplete penetrance J:34725
short humerus J:34725
short limbs J:34725
short radius J:34725
short snout J:34725
short ulna J:34725
small incisors J:82802
small thoracic cage J:34725
underdeveloped hair follicles J:82802
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory