92 phenotypes from 12 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Raxtm1.1(cre/ERT2)Sbls/Rax+ Yap1tm1Hmc/Yap1tm1Hmc involves: 129S6/SvEvTac * C57BL/6NCrl	abnormal glial cell physiology	J:304126
	abnormal retina morphology	J:304126
	retina gliosis	J:304126
Tg(MYH7-Yap1*S112A)#Eno/? involves: C3H * C57BL/6	abnormal myocardial trabeculae morphology	J:189577
	abnormal myocardium layer morphology	J:189577
	thick myocardium	J:189577
Yap1M1Btlr/Yap1M1Btlr C57BL/6J-Yap1M1Btlr	increased susceptibility to induced colitis	J:267549
Yap1tm1.1Dupa/Yap1tm1.1Dupa Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: 129P2/OlaHsd * C57BL/6 * DBA	abnormal bile duct development	J:162628
	abnormal bile duct morphology	J:162628
	abnormal hepatocyte morphology	J:162628
	enlarged liver	J:162628
	increased circulating alanine transaminase level	J:162628
	increased circulating bilirubin level	J:162628
	increased hepatocyte apoptosis	J:162628
	increased hepatocyte proliferation	J:162628
	liver cirrhosis	J:162628
	liver fibrosis	J:162628
	macrovesicular hepatic steatosis	J:162628
	pale liver	J:162628
Yap1tm1.1Dupa/Yap1tm1.1Dupa Tg(Vil1-cre)997Gum/0 involves: 129P2/OlaHsd * C57BL/6J * SJL	abnormal enterocyte proliferation	J:165471
	normal digestive/alimentary phenotype	J:165471
	increased enterocyte apoptosis	J:165471
	increased susceptibility to induced colitis	J:165471
	increased susceptibility to weight loss	J:165471
	increased susceptibility to xenobiotic induced morbidity/mortality	J:165471
Yap1tm1.1Eno/Yap1tm1.1Eno Nkx2-5tm1(cre)Rjs/Nkx2-5+ involves: 129S/SvEv	abnormal myocardium layer morphology	J:189577
	decreased heart rate	J:189577
	embryonic lethality during organogenesis, complete penetrance	J:189577
	thin myocardium	J:189577
Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 involves: 129S/SvEv * FVB/N	abnormal atrial thrombosis	J:200670
	abnormal cardiovascular system physiology	J:200670
	cardiac fibrosis	J:200670
	decreased cardiac muscle contractility	J:200670
	dilated cardiomyopathy	J:200670
	dilated heart ventricle	J:200670
	increased myocardial infarct size	J:200670
	lethargy	J:200670
	premature death	J:200670
	respiratory distress	J:200670
	thin ventricular wall	J:200670
Yap1tm1.1Fcam/Yap1tm1.1Fcam Tg(KRT14-cre)1Amc/0 involves: 129S4/SvJae * C57BL/6 * CBA	abnormal epidermal layer morphology	J:171057
	abnormal epidermal stem cell morphology	J:171057
	abnormal epidermis stratum basale morphology	J:171057
	abnormal epidermis stratum corneum morphology	J:171057
	abnormal skin condition	J:171057
	decreased cell proliferation	J:171057
	impaired skin barrier function	J:171057
	increased cell proliferation	J:171057
	thin epidermis	J:171057
	thin epidermis stratum basale	J:171057
	thin skin	J:171057
Yap1tm1.1Fcam/Yap1tm2.1Fcam Tg(KRT14-cre)1Amc/0 involves: 129S4/SvJae * C57BL/6 * CBA	abnormal epidermal layer morphology	J:171057
	abnormal skin morphology	J:171057
	decreased cell proliferation	J:171057
	neonatal lethality, complete penetrance	J:171057
	thin skin	J:171057
Yap1tm1.1Hmc/Yap1+ involves: 129S6/SvEvTac * BALB/c * C57BL/6 * C57BL/6NCrl	abnormal electroretinogram waveform feature	J:304126
	abnormal glial cell physiology	J:304126
	abnormal retina morphology	J:304126
	abnormal retina progenitor cell morphology	J:304126
	abnormal ribbon synapse morphology	J:304126
	cataract	J:304126
	decreased b-wave amplitude	J:304126
	decreased retina cone cell number	J:304126
	retina cone cell degeneration	J:304126
	retina gliosis	J:304126
Yap1tm1.2Dupa/Yap1tm1.2Dupa Not Specified	preweaning lethality, complete penetrance	J:162628
Yap1tm1b(KOMP)Mbp/Yap1tm1b(KOMP)Mbp C57BL/6N-Yap1tm1b(KOMP)Mbp/MbpMmucd	preweaning lethality, complete penetrance	J:211773
Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ involves: 129 * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl	abnormal kidney cortex morphology	J:195266
	abnormal kidney development	J:195266
	abnormal kidney medulla morphology	J:195266
	abnormal kidney papilla morphology	J:195266
	abnormal loop of Henle morphology	J:195266
	abnormal metanephros morphology	J:195266
	abnormal nephrogenic zone morphology	J:195266
	abnormal proximal convoluted tubule morphology	J:195266
	abnormal renal glomerulus morphology	J:195266
	abnormal renal tubule morphology	J:195266
	anuria	J:195266
	decreased renal glomerulus number	J:195266
	decreased renal tubule number	J:195266
	impaired branching involved in ureteric bud morphogenesis	J:195266
	podocyte foot process effacement	J:195266
	postnatal lethality, complete penetrance	J:195266
	renal hypoplasia	J:195266
Yap1tm1Smil/Yap1tm1Smil either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * C57BL/6J * CD-1)	abnormal blood vessel morphology	J:102253
	abnormal dorsal-ventral axis patterning	J:102253
	abnormal embryo development	J:102253
	abnormal embryonic tissue morphology	J:102253
	abnormal nervous system morphology	J:102253
	abnormal posterior primitive streak morphology	J:102253
	abnormal rostral-caudal body axis extension	J:102253
	abnormal ventral body wall morphology	J:102253
	abnormal visceral yolk sac morphology	J:102253
	absent visceral yolk sac blood islands	J:102253
	decreased embryo size	J:102253
	disorganized yolk sac vascular plexus	J:102253
	embryonic lethality during organogenesis, complete penetrance	J:102253
	embryonic-extraembryonic boundary constriction	J:102253
	excessive folding of visceral yolk sac	J:102253
	incomplete embryo turning	J:102253
Yap1tm2.1Dupa/Yap1tm2.1Dupa Not Specified	increased incidence of tumors by chemical induction	J:223215