Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pink1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PINK1
- Mouse genes Pink1
- Rat genes Pink1
- Zfish genes pink1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pink1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	PINK1	IDA		Human	PMID:14607334
Molecular Function	GO:0005524	ATP binding	Pink1	IDA		Mouse	MGI:MGI:3587805\|PMID:14607334
Molecular Function	GO:0055131	C3HC4-type RING finger domain binding	PINK1	IPI	UniProtKB:O60260	Human	PMID:19880420
Molecular Function	GO:0010857	calcium-dependent protein kinase activity	PINK1	IDA		Human	PMID:19880420
Molecular Function	GO:0016301	kinase activity	PINK1	IDA		Human	PMID:15824318
Molecular Function	GO:0016301	kinase activity	Pink1	IDA		Mouse	PMID:14607334
Molecular Function	GO:0000287	magnesium ion binding	PINK1	IDA		Human	PMID:14607334
Molecular Function	GO:0000287	magnesium ion binding	Pink1	IDA		Mouse	MGI:MGI:3587805\|PMID:14607334
Molecular Function	GO:0002020	protease binding	PINK1	IPI	UniProtKB:Q9H300	Human	PMID:21138942
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q99497	Human	PMID:16632486
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q12931	Human	PMID:17579517
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:O60260	Human	PMID:19229105
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q99497	Human	PMID:19229105
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:O60260	Human	PMID:20153330
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9GZQ8	Human	PMID:20153330
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9BPZ7	Human	PMID:21177249
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q8IXI2	Human	PMID:22078885
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:O60260	Human	PMID:23933751
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9Y3I1	Human	PMID:23933751
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9Y3I1-1	Human	PMID:23933751
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:O60260	Human	PMID:24357652
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9UL15	Human	PMID:24475098
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q8WXH5	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9UMX5	Human	PMID:31536960
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:O15392	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:P00491	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:P28347-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:P63010-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q13113	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q6DN90-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q8N895	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q99932-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9BYZ2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9UBQ0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PINK1	IPI	UniProtKB:Q9UHY8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pink1	IPI	UniProtKB:Q9CQ45	Mouse	MGI:MGI:6383486\|PMID:31536960
Molecular Function	GO:0005515	protein binding	Pink1	IPI	RGD:1359733	Rat	PMID:17579517\|RGD:8693356
Molecular Function	GO:0005515	protein binding	Pink1	IPI	UniProtKB:Q5XHZ0	Rat	PMID:17579517\|RGD:8693356
Molecular Function	GO:0005515	protein binding	Pink1	IPI	UniProtKB:Q6IUR5	Rat	PMID:31536960\|RGD:15090841
Molecular Function	GO:0004672	protein kinase activity	PINK1	IMP		Human	PMID:25527497
Molecular Function	GO:0004672	protein kinase activity	PINK1	IMP		Human	PMID:32047033
Molecular Function	GO:0043422	protein kinase B binding	PINK1	IDA		Human	PMID:21177249
Molecular Function	GO:0106310	protein serine kinase activity	PINK1	IMP		Human	PMID:32484300
Molecular Function	GO:0106310	protein serine kinase activity	Pink1	IMP		Mouse	MGI:MGI:6508521\|PMID:32484300
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PINK1	IDA		Human	PMID:14607334
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PINK1	IDA		Human	PMID:17579517
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PINK1	IDA		Human	PMID:19880420
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PINK1	IDA		Human	PMID:24784582
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PINK1	IDA		Human	PMID:25527291
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pink1	IMP		Mouse	MGI:MGI:5574406\|PMID:24784582
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pink1	IDA		Mouse	MGI:MGI:3587805\|PMID:14607334
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pink1	IMP		Mouse	PMID:25305081
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pink1	IDA		Mouse	PMID:24652937
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pink1	IMP		Rat	PMID:17579517\|RGD:8693356
Molecular Function	GO:0044877	protein-containing complex binding	PINK1	IMP		Human	PMID:24270810
Molecular Function	GO:1904841	TORC2 complex binding	PINK1	IPI	UniProtKB:Q6R327	Human	PMID:21177249
Molecular Function	GO:0031625	ubiquitin protein ligase binding	PINK1	IPI	UniProtKB:O60260	Human	PMID:20798600
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Pink1	IPI	RGD:61797	Rat	PMID:28608965\|RGD:13432560
Cellular Component	GO:0097449	astrocyte projection	PINK1	IDA		Human	PMID:16702191
Cellular Component	GO:0030424	axon	PINK1	IDA		Human	PMID:16702191
Cellular Component	GO:0044297	cell body	PINK1	IDA		Human	PMID:16702191
Cellular Component	GO:0000785	chromatin	PINK1	IDA		Human	PMID:24798695
Cellular Component	GO:0005737	cytoplasm	PINK1	IDA		Human	PMID:16702191
Cellular Component	GO:0005856	cytoskeleton	PINK1	IDA		Human	PMID:24798695
Cellular Component	GO:0005829	cytosol	PINK1	IDA		Human	PMID:18957282
Cellular Component	GO:0005829	cytosol	PINK1	IDA		Human	PMID:19229105
Cellular Component	GO:0005829	cytosol	PINK1	IDA		Human	PMID:19880420
Cellular Component	GO:0005829	cytosol	PINK1	IDA		Human	PMID:20798600
Cellular Component	GO:0005829	cytosol	PINK1	IDA		Human	PMID:21138942
Cellular Component	GO:0005829	cytosol	PINK1	IDA		Human	PMID:21426348
Cellular Component	GO:0005829	cytosol	PINK1	IDA		Human	PMID:24798695
Cellular Component	GO:0005829	cytosol	pink1	IDA		Zfish	PMID:18701682
Cellular Component	GO:0005783	endoplasmic reticulum	PINK1	IDA		Human	PMID:31536960
Cellular Component	GO:0005783	endoplasmic reticulum	Pink1	IDA		Mouse	MGI:MGI:6383486\|PMID:31536960
Cellular Component	GO:0005783	endoplasmic reticulum	Pink1	IDA		Rat	PMID:31536960\|RGD:15090841
Cellular Component	GO:0030426	growth cone	Pink1	IDA		Rat	PMID:22238344\|RGD:12904027
Cellular Component	GO:0016020	membrane	PINK1	IDA		Human	PMID:24798695
Cellular Component	GO:0005743	mitochondrial inner membrane	PINK1	IDA		Human	PMID:17579517
Cellular Component	GO:0005743	mitochondrial inner membrane	PINK1	IDA		Human	PMID:21426348
Cellular Component	GO:0005743	mitochondrial inner membrane	Pink1	IDA		Mouse	PMID:24652937
Cellular Component	GO:0005743	mitochondrial inner membrane	Pink1	IDA		Rat	PMID:16702191\|RGD:2290300
Cellular Component	GO:0005743	mitochondrial inner membrane	Pink1	IDA		Rat	PMID:17579517\|RGD:8693356
Cellular Component	GO:0005758	mitochondrial intermembrane space	PINK1	IDA		Human	PMID:17579517
Cellular Component	GO:0005758	mitochondrial intermembrane space	PINK1	IDA		Human	PMID:21426348
Cellular Component	GO:0005758	mitochondrial intermembrane space	Pink1	IDA		Rat	PMID:17579517\|RGD:8693356
Cellular Component	GO:0005741	mitochondrial outer membrane	PINK1	IDA		Human	PMID:18687899
Cellular Component	GO:0005741	mitochondrial outer membrane	PINK1	IDA		Human	PMID:21426348
Cellular Component	GO:0005741	mitochondrial outer membrane	PINK1	IMP		Human	PMID:25527497
Cellular Component	GO:0005741	mitochondrial outer membrane	Pink1	IDA		Rat	PMID:16702191\|RGD:2290300
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:15087508
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:15824318
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:16702191
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:18957282
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:19229105
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:20798600
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:21138942
Cellular Component	GO:0005739	mitochondrion	PINK1	IGI	UniProtKB:Q9H300	Human	PMID:21355049
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:22354088
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:23933751
Cellular Component	GO:0005739	mitochondrion	PINK1	IMP		Human	PMID:24184327
Cellular Component	GO:0005739	mitochondrion	PINK1	IDA		Human	PMID:31536960
Cellular Component	GO:0005739	mitochondrion	Pink1	IDA		Mouse	MGI:MGI:6383486\|PMID:31536960
Cellular Component	GO:0005739	mitochondrion	Pink1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Pink1	IDA		Rat	PMID:31536960\|RGD:15090841
Cellular Component	GO:0005739	mitochondrion	pink1	IDA		Zfish	PMID:18701682
Cellular Component	GO:0005634	nucleus	PINK1	IDA		Human	PMID:24798695
Cellular Component	GO:0048471	perinuclear region of cytoplasm	PINK1	IDA		Human	PMID:16702191
Biological Process	GO:0000422	autophagy of mitochondrion	PINK1	IMP		Human	PMID:20798600
Biological Process	GO:0000422	autophagy of mitochondrion	PINK1	IMP		Human	PMID:23933751
Biological Process	GO:0000422	autophagy of mitochondrion	PINK1	IMP		Human	PMID:24896179
Biological Process	GO:0000422	autophagy of mitochondrion	pink1	IMP	ZFIN:ZDB-GENO-170925-8	Zfish	PMID:28366621
Biological Process	GO:0050432	catecholamine secretion	Pink1	IMP	MGI:MGI:3716083	Mouse	PMID:17563363
Biological Process	GO:1904881	cellular response to hydrogen sulfide	Pink1	IDA		Rat	PMID:28608965\|RGD:13432560
Biological Process	GO:0071456	cellular response to hypoxia	PINK1	IMP		Human	PMID:24553947
Biological Process	GO:0071456	cellular response to hypoxia	Pink1	IMP		Mouse	MGI:MGI:5558956\|PMID:24553947
Biological Process	GO:0034599	cellular response to oxidative stress	PINK1	IMP		Human	PMID:22764206
Biological Process	GO:0034599	cellular response to oxidative stress	Pink1	IMP		Mouse	MGI:MGI:3813389\|PMID:18687901
Biological Process	GO:0097237	cellular response to toxic substance	Pink1	IMP		Mouse	MGI:MGI:5431185\|PMID:22511790
Biological Process	GO:0014046	dopamine secretion	Pink1	IMP	MGI:MGI:3716083	Mouse	PMID:17563363
Biological Process	GO:0071542	dopaminergic neuron differentiation	pink1	IMP	ZFIN:ZDB-GENO-220818-2	Zfish	PMID:32859696
Biological Process	GO:0071542	dopaminergic neuron differentiation	pink1	IMP	ZFIN:ZDB-MRPHLNO-101007-6	Zfish	PMID:20600915
Biological Process	GO:0071542	dopaminergic neuron differentiation	pink1	IMP	ZFIN:ZDB-GENO-140514-3	Zfish	PMID:24027110
Biological Process	GO:0071542	dopaminergic neuron differentiation	pink1	IMP	ZFIN:ZDB-MRPHLNO-140225-6	Zfish	PMID:24027110
Biological Process	GO:0071542	dopaminergic neuron differentiation	pink1	IMP	ZFIN:ZDB-MRPHLNO-081202-1	Zfish	PMID:20141529
Biological Process	GO:0071542	dopaminergic neuron differentiation	pink1	IMP	ZFIN:ZDB-MRPHLNO-101007-5	Zfish	PMID:20600915
Biological Process	GO:0071542	dopaminergic neuron differentiation	pink1	IMP	ZFIN:ZDB-MRPHLNO-100428-1	Zfish	PMID:20141529
Biological Process	GO:0051649	establishment of localization in cell	Pink1	IMP	MGI:MGI:3716083	Mouse	PMID:17563363
Biological Process	GO:0072655	establishment of protein localization to mitochondrion	PINK1	IMP		Human	PMID:18957282
Biological Process	GO:0072655	establishment of protein localization to mitochondrion	PINK1	IMP		Human	PMID:25527497
Biological Process	GO:0030097	hemopoiesis	PINK1	IGI	UniProtKB:Q8CGY8	Human	PMID:33406421
Biological Process	GO:0035556	intracellular signal transduction	PINK1	IDA		Human	PMID:14607334
Biological Process	GO:0035556	intracellular signal transduction	Pink1	IDA		Mouse	MGI:MGI:3587805\|PMID:14607334
Biological Process	GO:0072656	maintenance of protein location in mitochondrion	PINK1	IMP		Human	PMID:25527497
Biological Process	GO:0000266	mitochondrial fission	Pink1	HMP		Rat	PMID:25421206\|RGD:11560775
Biological Process	GO:0007005	mitochondrion organization	PINK1	IMP		Human	PMID:18560593
Biological Process	GO:0007005	mitochondrion organization	pink1	IMP	ZFIN:ZDB-GENO-140514-3	Zfish	PMID:24027110
Biological Process	GO:0099074	mitochondrion to lysosome transport	PINK1	IMP		Human	PMID:24446486
Biological Process	GO:0000423	mitophagy	PINK1	IGI	UniProtKB:Q8CGY8	Human	PMID:33406421
Biological Process	GO:0043066	negative regulation of apoptotic process	Pink1	IMP		Rat	PMID:17579517\|RGD:8693356
Biological Process	GO:1902902	negative regulation of autophagosome assembly	PINK1	IMP		Human	PMID:19279012
Biological Process	GO:0031999	negative regulation of fatty acid beta-oxidation	Pink1	HMP		Rat	PMID:25421206\|RGD:11560775
Biological Process	GO:0010629	negative regulation of gene expression	Pink1	IMP		Mouse	MGI:MGI:5582017\|PMID:24475098
Biological Process	GO:0010629	negative regulation of gene expression	Pink1	IMP		Rat	PMID:24475098\|RGD:10047288
Biological Process	GO:1903384	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	PINK1	IDA		Human	PMID:21177249
Biological Process	GO:1903384	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	PINK1	IMP		Human	PMID:23261939
Biological Process	GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	Pink1	IMP		Mouse	MGI:MGI:5558956\|PMID:24553947
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	PINK1	IDA		Human	PMID:15087508
Biological Process	GO:1903751	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	PINK1	IDA		Human	PMID:17579517
Biological Process	GO:1903751	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Pink1	IMP		Rat	PMID:17579517\|RGD:8693356
Biological Process	GO:0016242	negative regulation of macroautophagy	PINK1	IMP		Human	PMID:19279012
Biological Process	GO:0090258	negative regulation of mitochondrial fission	PINK1	IMP		Human	PMID:19279012
Biological Process	GO:1901525	negative regulation of mitophagy	PINK1	IMP		Human	PMID:19279012
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	PINK1	IMP		Human	PMID:18560593
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Pink1	IMP		Mouse	MGI:MGI:3847070\|PMID:18560593
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Pink1	IMP		Mouse	MGI:MGI:5431185\|PMID:22511790
Biological Process	GO:1901215	negative regulation of neuron death	Pink1	IMP		Rat	PMID:20698836\|RGD:13463453
Biological Process	GO:1903202	negative regulation of oxidative stress-induced cell death	PINK1	IDA		Human	PMID:16632486
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	PINK1	IMP		Human	PMID:18560593
Biological Process	GO:0051402	neuron apoptotic process	pink1	IMP	ZFIN:ZDB-MRPHLNO-081202-1,ZFIN:ZDB-MRPHLNO-081202-2	Zfish	PMID:18701682
Biological Process	GO:0048823	nucleate erythrocyte development	pink1	IMP	ZFIN:ZDB-MRPHLNO-101007-5	Zfish	PMID:23454196
Biological Process	GO:0036289	peptidyl-serine autophosphorylation	PINK1	IMP		Human	PMID:25527497
Biological Process	GO:0018105	peptidyl-serine phosphorylation	PINK1	IDA		Human	PMID:17579517
Biological Process	GO:0018105	peptidyl-serine phosphorylation	PINK1	IDA		Human	PMID:19880420
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Pink1	IMP		Rat	PMID:17579517\|RGD:8693356
Biological Process	GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	Pink1	IMP		Rat	PMID:25154397\|RGD:12904014
Biological Process	GO:0033605	positive regulation of catecholamine secretion	Pink1	IMP	MGI:MGI:3716083	Mouse	PMID:17563363
Biological Process	GO:1903852	positive regulation of cristae formation	PINK1	IMP		Human	PMID:19279012
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Pink1	IMP		Mouse	MGI:MGI:5558956\|PMID:24553947
Biological Process	GO:0033603	positive regulation of dopamine secretion	Pink1	IMP	MGI:MGI:3716083	Mouse	PMID:17563363
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	PINK1	IDA		Human	PMID:19880420
Biological Process	GO:0016239	positive regulation of macroautophagy	PINK1	IMP		Human	PMID:20871098
Biological Process	GO:1902958	positive regulation of mitochondrial electron transport, NADH to ubiquinone	Pink1	IMP		Mouse	PMID:24652937
Biological Process	GO:0090141	positive regulation of mitochondrial fission	Pink1	IMP		Rat	PMID:21613270\|RGD:12903967
Biological Process	GO:0098779	positive regulation of mitophagy in response to mitochondrial depolarization	PINK1	IMP		Human	PMID:20871098
Biological Process	GO:1904783	positive regulation of NMDA glutamate receptor activity	Pink1	IMP		Rat	PMID:20698836\|RGD:13463453
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	PINK1	IDA		Human	PMID:21177249
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	PINK1	IMP		Human	PMID:24660806
Biological Process	GO:0035307	positive regulation of protein dephosphorylation	Pink1	IMP		Mouse	MGI:MGI:5558956\|PMID:24553947
Biological Process	GO:0001934	positive regulation of protein phosphorylation	PINK1	IDA		Human	PMID:25244949
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Pink1	IMP		Rat	PMID:17579517\|RGD:8693356
Biological Process	GO:1903955	positive regulation of protein targeting to mitochondrion	PINK1	HMP		Human	PMID:24270810
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	PINK1	IMP		Human	PMID:19880420
Biological Process	GO:0032226	positive regulation of synaptic transmission, dopaminergic	Pink1	IMP	MGI:MGI:3716083	Mouse	PMID:17563363
Biological Process	GO:0045727	positive regulation of translation	Pink1	IMP		Mouse	MGI:MGI:5558956\|PMID:24553947
Biological Process	GO:0006468	protein phosphorylation	PINK1	IDA		Human	PMID:14607334
Biological Process	GO:0006468	protein phosphorylation	PINK1	IMP		Human	PMID:18957282
Biological Process	GO:0006468	protein phosphorylation	PINK1	IDA		Human	PMID:21177249
Biological Process	GO:0006468	protein phosphorylation	PINK1	IDA		Human	PMID:25527291
Biological Process	GO:0006468	protein phosphorylation	PINK1	IMP		Human	PMID:25527497
Biological Process	GO:0006468	protein phosphorylation	PINK1	IDA		Human	PMID:32139798
Biological Process	GO:0006468	protein phosphorylation	Pink1	IDA		Mouse	MGI:MGI:3587805\|PMID:14607334
Biological Process	GO:0006468	protein phosphorylation	Pink1	IDA		Mouse	MGI:MGI:7432481\|PMID:32139798
Biological Process	GO:0050821	protein stabilization	PINK1	IMP		Human	PMID:19229105
Biological Process	GO:0050821	protein stabilization	Pink1	IMP		Mouse	MGI:MGI:3837120\|PMID:19229105
Biological Process	GO:0016567	protein ubiquitination	PINK1	IMP		Human	PMID:23933751
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	PINK1	IMP		Human	PMID:24446486
Biological Process	GO:0010310	regulation of hydrogen peroxide metabolic process	Pink1	IMP		Mouse	MGI:MGI:5558956\|PMID:24553947
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	PINK1	IMP		Human	PMID:18560593
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	PINK1	IMP		Human	PMID:21138942
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	PINK1	IGI	UniProtKB:Q9UL15	Human	PMID:24475098
Biological Process	GO:0010821	regulation of mitochondrion organization	PINK1	IMP		Human	PMID:21508222
Biological Process	GO:0043523	regulation of neuron apoptotic process	Pink1	IMP		Mouse	MGI:MGI:5431185\|PMID:22511790
Biological Process	GO:0002082	regulation of oxidative phosphorylation	PINK1	IDA		Human	PMID:20871098
Biological Process	GO:1903214	regulation of protein targeting to mitochondrion	PINK1	IGI	UniProtKB:Q9BXM7	Human	PMID:21508222
Biological Process	GO:1903214	regulation of protein targeting to mitochondrion	PINK1	IMP		Human	PMID:23212910
Biological Process	GO:1903214	regulation of protein targeting to mitochondrion	PINK1	IDA		Human	PMID:25244949
Biological Process	GO:0031396	regulation of protein ubiquitination	PINK1	IDA		Human	PMID:19880420
Biological Process	GO:0031396	regulation of protein ubiquitination	PINK1	IMP		Human	PMID:20871098
Biological Process	GO:0031396	regulation of protein ubiquitination	PINK1	IMP		Human	PMID:23212910
Biological Process	GO:0043254	regulation of protein-containing complex assembly	PINK1	IDA		Human	PMID:19880420
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	PINK1	IMP		Human	PMID:21138942
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	PINK1	IGI	UniProtKB:Q9UL15	Human	PMID:24475098
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	pink1	IMP	ZFIN:ZDB-MRPHLNO-101007-5	Zfish	PMID:23454196
Biological Process	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	pink1	IMP	ZFIN:ZDB-MRPHLNO-101007-5	Zfish	PMID:23454196
Biological Process	GO:0022904	respiratory electron transport chain	Pink1	IMP		Mouse	MGI:MGI:3813389\|PMID:18687901
Biological Process	GO:0002931	response to ischemia	Pink1	IEP		Rat	PMID:25791474\|RGD:12903964
Biological Process	GO:0006979	response to oxidative stress	PINK1	IGI	UniProtKB:Q9UL15	Human	PMID:24475098
Biological Process	GO:0060872	semicircular canal development	pink1	IMP	ZFIN:ZDB-MRPHLNO-090818-3	Zfish	PMID:19320994
Biological Process	GO:0036269	swimming behavior	pink1	IMP	ZFIN:ZDB-GENO-220818-2	Zfish	PMID:32859696

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.