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Gene Ontology Browser
Term Detail
GO term:negative regulation of macroautophagy
Synonym: down regulation of macroautophagy
Synonym: down-regulation of macroautophagy
Synonym: downregulation of macroautophagy
Synonym: inhibition of macroautophagy
Synonym: negative regulation of starvation-induced autophagy
GO id:GO:0016242
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.
Number of paths to term: 18

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-anegative regulation of biological process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-aregulation of autophagy
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of cellular process
                                is-aregulation of autophagy
                                        is-aregulation of macroautophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-apositive regulation of macroautophagy +
                                                is-aregulation of aggrephagy +
                                                is-aregulation of autophagosome assembly +
                                                is-aregulation of autophagosome maturation +
                                                is-aregulation of lipophagy +
                                                is-aregulation of macromitophagy +
                                                is-aregulation of xenophagy +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-aautophagy
                                is-amacroautophagy
                                        is-aaggrephagy +
                                        part-ofautophagosome maturation +
                                        part-ofautophagosome organization +
                                        part-ofengulfment of target by autophagosome
                                        is-aglycophagy
                                        is-alipophagy +
                                        is-amacromitophagy +
                                        is-amacropexophagy
                                        negatively-regulatesnegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                is-anegative regulation of aggrephagy
                                                is-anegative regulation of autophagosome assembly
                                                is-anegative regulation of autophagosome maturation
                                                is-anegative regulation of lipophagy
                                                is-anegative regulation of macroautophagy by TORC1 signaling
                                                is-anegative regulation of macromitophagy +
                                                is-anegative regulation of xenophagy
                                        negatively-regulatesnegative regulation of macroautophagy by TORC1 signaling
                                        positively-regulatespositive regulation of macroautophagy +
                                        part-ofregulation of autophagosome size +
                                        regulatesregulation of macroautophagy +
                                        is-areticulophagy
                                        is-aribophagy
                                        is-axenophagy +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-aautophagy
                                is-amacroautophagy
                                        regulatesregulation of macroautophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-apositive regulation of macroautophagy +
                                                is-aregulation of aggrephagy +
                                                is-aregulation of autophagosome assembly +
                                                is-aregulation of autophagosome maturation +
                                                is-aregulation of lipophagy +
                                                is-aregulation of macromitophagy +
                                                is-aregulation of xenophagy +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-aautophagy
                                negatively-regulatesnegative regulation of autophagy
                                        is-anegative regulation of chaperone-mediated autophagy
                                        is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                is-anegative regulation of aggrephagy
                                                is-anegative regulation of autophagosome assembly
                                                is-anegative regulation of autophagosome maturation
                                                is-anegative regulation of lipophagy
                                                is-anegative regulation of macroautophagy by TORC1 signaling
                                                is-anegative regulation of macromitophagy +
                                                is-anegative regulation of xenophagy
                                        is-anegative regulation of mitophagy +
                                        is-anegative regulation of protein targeting to vacuole involved in autophagy
                                        is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-aautophagy
                                regulatesregulation of autophagy
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-aautophagy
                                regulatesregulation of autophagy
                                        is-aregulation of macroautophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-apositive regulation of macroautophagy +
                                                is-aregulation of aggrephagy +
                                                is-aregulation of autophagosome assembly +
                                                is-aregulation of autophagosome maturation +
                                                is-aregulation of lipophagy +
                                                is-aregulation of macromitophagy +
                                                is-aregulation of xenophagy +


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        negatively-regulatesnegative regulation of cellular process
                                is-anegative regulation of autophagy
                                        is-anegative regulation of chaperone-mediated autophagy
                                        is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                is-anegative regulation of aggrephagy
                                                is-anegative regulation of autophagosome assembly
                                                is-anegative regulation of autophagosome maturation
                                                is-anegative regulation of lipophagy
                                                is-anegative regulation of macroautophagy by TORC1 signaling
                                                is-anegative regulation of macromitophagy +
                                                is-anegative regulation of xenophagy
                                        is-anegative regulation of mitophagy +
                                        is-anegative regulation of protein targeting to vacuole involved in autophagy
                                        is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of autophagy
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of autophagy
                                        is-aregulation of macroautophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-apositive regulation of macroautophagy +
                                                is-aregulation of aggrephagy +
                                                is-aregulation of autophagosome assembly +
                                                is-aregulation of autophagosome maturation +
                                                is-aregulation of lipophagy +
                                                is-aregulation of macromitophagy +
                                                is-aregulation of xenophagy +


obsolete Gene_Ontology
        is-abiological_process
                negatively-regulatesnegative regulation of biological process
                        is-anegative regulation of cellular process
                                is-anegative regulation of autophagy
                                        is-anegative regulation of chaperone-mediated autophagy
                                        is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                is-anegative regulation of aggrephagy
                                                is-anegative regulation of autophagosome assembly
                                                is-anegative regulation of autophagosome maturation
                                                is-anegative regulation of lipophagy
                                                is-anegative regulation of macroautophagy by TORC1 signaling
                                                is-anegative regulation of macromitophagy +
                                                is-anegative regulation of xenophagy
                                        is-anegative regulation of mitophagy +
                                        is-anegative regulation of protein targeting to vacuole involved in autophagy
                                        is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-aregulation of biological process
                        is-anegative regulation of biological process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-aregulation of biological process
                        is-aregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-aregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of autophagy
                                        is-anegative regulation of autophagy
                                                is-anegative regulation of chaperone-mediated autophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-anegative regulation of mitophagy +
                                                is-anegative regulation of protein targeting to vacuole involved in autophagy
                                                is-asuppression by virus of host autophagy


obsolete Gene_Ontology
        is-abiological_process
                is-aregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of autophagy
                                        is-aregulation of macroautophagy
                                                is-anegative regulation of macroautophagy [GO:0016242] (24 genes, 30 annotations)
                                                        is-anegative regulation of aggrephagy
                                                        is-anegative regulation of autophagosome assembly
                                                        is-anegative regulation of autophagosome maturation
                                                        is-anegative regulation of lipophagy
                                                        is-anegative regulation of macroautophagy by TORC1 signaling
                                                        is-anegative regulation of macromitophagy +
                                                        is-anegative regulation of xenophagy
                                                is-apositive regulation of macroautophagy +
                                                is-aregulation of aggrephagy +
                                                is-aregulation of autophagosome assembly +
                                                is-aregulation of autophagosome maturation +
                                                is-aregulation of lipophagy +
                                                is-aregulation of macromitophagy +
                                                is-aregulation of xenophagy +


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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory