Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gria3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GRIA3
- Mouse genes Gria3
- Rat genes Gria3
- Zfish genes gria3a,gria3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gria3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004971	AMPA glutamate receptor activity	GRIA3	IDA		Human	PMID:21172611
Molecular Function	GO:0004971	AMPA glutamate receptor activity	Gria3	IDA		Rat	PMID:11834304\|RGD:728843
Molecular Function	GO:0001540	amyloid-beta binding	Gria3	IPI	ComplexPortal:CPX-1134,UniProtKB:P19491	Rat	PMID:20032460\|RGD:12907563
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	Gria3	IDA		Rat	PMID:11834304\|RGD:728843
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIA3	IDA		Human	PMID:12670305
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIA3	IMP		Human	PMID:12670305
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:Q64337	Mouse	MGI:MGI:5908340\|PMID:19004011
Molecular Function	GO:0005515	protein binding	Gria3	IPI	PR:P23819	Mouse	PMID:14687553
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:Q9EP80	Rat	PMID:10027300\|RGD:69384
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:Q9EP80	Rat	PMID:10340301\|RGD:8553694
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:P97879	Rat	PMID:11891216\|RGD:8553442
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:Q9EP80	Rat	PMID:11891216\|RGD:8553442
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:Q8VHW8	Rat	PMID:18817736\|RGD:8554789
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:P19491-2	Rat	PMID:26966189\|RGD:13432296
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:P19491-2	Rat	PMID:30975770\|RGD:150521641
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:P97879	Rat	PMID:9647694\|RGD:8553765
Molecular Function	GO:0005515	protein binding	Gria3	IPI	UniProtKB:Q9QUL6	Rat	PMID:9697854\|RGD:8553822
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gria3	IDA		Mouse	PMID:28103481
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gria3	IMP		Mouse	PMID:28103481
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Gria3	IDA		Mouse	PMID:22632720
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Gria3	IDA		Rat	PMID:19265014\|RGD:8554136
Cellular Component	GO:0032279	asymmetric synapse	Gria3	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0030425	dendrite	Gria3	IDA		Rat	PMID:15844209\|RGD:1642495
Cellular Component	GO:0043198	dendritic shaft	Gria3	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0043197	dendritic spine	Gria3	IDA		Rat	PMID:11348590\|RGD:8553683
Cellular Component	GO:0043197	dendritic spine	Gria3	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0043197	dendritic spine	Gria3	IDA		Rat	PMID:17207780\|RGD:1642304
Cellular Component	GO:0098978	glutamatergic synapse	Gria3	IDA		Rat	PMID:12761821\|RGD:13702231
Cellular Component	GO:0016020	membrane	Gria3	IDA		Mouse	PMID:17093100
Cellular Component	GO:0043025	neuronal cell body	Gria3	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Gria3	IDA		Mouse	PMID:28103481
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Gria3	IMP		Mouse	PMID:28103481
Cellular Component	GO:0043204	perikaryon	Gria3	IDA		Rat	PMID:15844209\|RGD:1642495
Cellular Component	GO:0014069	postsynaptic density	Gria3	IDA		Rat	PMID:10027300\|RGD:69384
Cellular Component	GO:0014069	postsynaptic density	Gria3	IDA		Rat	PMID:12077196\|RGD:1600985
Cellular Component	GO:0014069	postsynaptic density	Gria3	IDA		Rat	PMID:17207780\|RGD:1642304
Cellular Component	GO:0098839	postsynaptic density membrane	Gria3	IDA		Rat	PMID:12761821\|RGD:13702231
Cellular Component	GO:0045211	postsynaptic membrane	Gria3	IDA		Mouse	PMID:19063943
Cellular Component	GO:0045211	postsynaptic membrane	Gria3	IDA		Rat	PMID:16903873\|RGD:2316535
Cellular Component	GO:0048787	presynaptic active zone membrane	Gria3	IDA		Rat	PMID:12761821\|RGD:13702231
Cellular Component	GO:0042734	presynaptic membrane	Gria3	IDA		Rat	PMID:16903873\|RGD:2316535
Cellular Component	GO:0032991	protein-containing complex	Gria3	IPI	UniProtKB:Q9EP80	Rat	PMID:10027300\|RGD:69384
Cellular Component	GO:0043083	synaptic cleft	Gria3	IDA		Rat	PMID:17207780\|RGD:1642304
Cellular Component	GO:0043195	terminal bouton	Gria3	IDA		Rat	PMID:15844209\|RGD:1642495
Biological Process	GO:0007268	chemical synaptic transmission	Gria3	IMP		Mouse	MGI:MGI:6114265\|PMID:28103481
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Gria3	IMP		Mouse	MGI:MGI:6114265\|PMID:28103481
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Gria3	IMP		Mouse	MGI:MGI:6114265\|PMID:28103481
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Gria3	IMP		Mouse	MGI:MGI:6114265\|PMID:28103481
Biological Process	GO:0001919	regulation of receptor recycling	Gria3	IMP		Rat	PMID:11348590\|RGD:8553683
Biological Process	GO:0060992	response to fungicide	Gria3	IEP		Rat	PMID:19591855\|RGD:2325972
Biological Process	GO:0010226	response to lithium ion	Gria3	IEP		Rat	PMID:15269270\|RGD:8553901

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.