| GO term: | alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex |
| Synonym: | AMPA receptor |
| Synonym: | AMPA-selective glutamate receptor complex |
| GO id: | GO:0032281 |
| Definition: | An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. |
| Number of paths to term: | 23 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partcell peripheryplasma membraneplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcellcell partcell peripheryplasma membraneplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcellcell partplasma membraneplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcellcell partplasma membraneplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcellcell partplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcellcell partplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcell partcell peripheryplasma membraneplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcell partcell peripheryplasma membraneplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcell partplasma membraneplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcell partplasma membraneplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcell partplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentcell partplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmacromolecular complexprotein complexreceptor complexionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembranemembrane partintrinsic to membraneintegral to membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembranemembrane partintrinsic to membraneintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembranemembrane partplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembranemembrane partplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembraneplasma membraneplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembraneplasma membraneplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembrane partintrinsic to membraneintegral to membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembrane partintrinsic to membraneintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembrane partplasma membrane partintrinsic to plasma membraneintegral to plasma membraneionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexcellular_componentmembrane partplasma membrane partionotropic glutamate receptor complexalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [GO:0032281] (28 genes, 35 annotations)kainate selective glutamate receptor complexN-methyl-D-aspartate selective glutamate receptor complexMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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