Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes F12
  • Mouse genes F12
  • Rat genes F12
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set F12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008233	peptidase activity	F12	IMP	MGI:MGI:3720935	Mouse	PMID:15351846
Molecular Function	GO:0005515	protein binding	F12	IPI	UniProtKB:P04196	Human	PMID:21304106
Molecular Function	GO:0005515	protein binding	F12	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	F12	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	F12	IPI	UniProtKB:Q07021	Human	PMID:8710908
Molecular Function	GO:0004252	serine-type endopeptidase activity	F12	IDA		Human	PMID:18725990
Molecular Function	GO:0004252	serine-type endopeptidase activity	F12	IDA		Human	PMID:6793628
Cellular Component	GO:0062023	collagen-containing extracellular matrix	F12	HDA		Human	PMID:25037231
Cellular Component	GO:0070062	extracellular exosome	F12	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	F12	IDA		Human	PMID:6793628
Cellular Component	GO:0005615	extracellular space	F12	IMP	MGI:MGI:3720935	Mouse	PMID:15351846
Cellular Component	GO:0005615	extracellular space	F12	IDA		Rat	PMID:2324612|RGD:11041779
Biological Process	GO:0007596	blood coagulation	F12	IMP	MGI:MGI:3720935	Mouse	PMID:15351846
Biological Process	GO:0007596	blood coagulation	F12	IDA		Rat	PMID:10048754|RGD:2290183
Biological Process	GO:0002542	Factor XII activation	F12	IDA		Human	PMID:18725990
Biological Process	GO:0002353	plasma kallikrein-kinin cascade	F12	IDA		Human	PMID:18725990
Biological Process	GO:0002353	plasma kallikrein-kinin cascade	F12	IDA		Human	PMID:6793628
Biological Process	GO:0030194	positive regulation of blood coagulation	F12	IDA		Human	PMID:6793628
Biological Process	GO:0051919	positive regulation of fibrinolysis	F12	IDA		Human	PMID:89876
Biological Process	GO:0010756	positive regulation of plasminogen activation	F12	IDA		Human	PMID:89876
Biological Process	GO:0016540	protein autoprocessing	F12	IDA		Human	PMID:18725990
Biological Process	GO:0016485	protein processing	F12	IDA		Human	PMID:18725990
Biological Process	GO:0051788	response to misfolded protein	F12	IDA		Human	PMID:18725990
Biological Process	GO:0031638	zymogen activation	F12	IDA		Human	PMID:18725990
Biological Process	GO:0031638	zymogen activation	F12	IDA		Human	PMID:6793628
Biological Process	GO:0031638	zymogen activation	F12	IDA		Human	PMID:89876

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern