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Gene Ontology Browser
Term Detail
GO term:zymogen activation
Synonym: zymogen activation by proteolytic cleavage
GO id:GO:0031638
Definition:The proteolytic processing of an inactive enzyme to an active form.
Number of paths to term: 3

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-agene expression
                                                part-ofprotein maturation
                                                        is-aprotein processing
                                                                is-aactivation of plasma proteins involved in acute inflammatory response +
                                                                is-aCAAX-box protein processing
                                                                is-adibasic protein processing +
                                                                is-amitochondrial protein processing +
                                                                negatively-regulatesnegative regulation of protein processing +
                                                                is-aNotch receptor processing, ligand-independent
                                                                is-apeptide bond cleavage involved in epidermal growth factor receptor ligand maturation
                                                                is-apeptide hormone processing +
                                                                positively-regulatespositive regulation of protein processing +
                                                                is-aprotein autoprocessing
                                                                is-aprotein initiator methionine removal involved in protein maturation
                                                                is-aprotein processing in phagocytic vesicle
                                                                is-aprotein splicing +
                                                                regulatesregulation of protein processing +
                                                                is-asignal peptide processing +
                                                                is-asterol regulatory element binding protein cleavage +
                                                                is-avacuolar protein processing +
                                                                is-aviral protein processing
                                                                is-azymogen activation [GO:0031638] (101 genes, 133 annotations)
                                                                        is-aactivation of cysteine-type endopeptidase activity +
                                                                        is-aplasminogen activation +
                                                                        is-atrypsinogen activation
                                                                        is-azymogen activation in other organism +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein maturation
                                                        is-aprotein processing
                                                                is-aactivation of plasma proteins involved in acute inflammatory response +
                                                                is-aCAAX-box protein processing
                                                                is-adibasic protein processing +
                                                                is-amitochondrial protein processing +
                                                                negatively-regulatesnegative regulation of protein processing +
                                                                is-aNotch receptor processing, ligand-independent
                                                                is-apeptide bond cleavage involved in epidermal growth factor receptor ligand maturation
                                                                is-apeptide hormone processing +
                                                                positively-regulatespositive regulation of protein processing +
                                                                is-aprotein autoprocessing
                                                                is-aprotein initiator methionine removal involved in protein maturation
                                                                is-aprotein processing in phagocytic vesicle
                                                                is-aprotein splicing +
                                                                regulatesregulation of protein processing +
                                                                is-asignal peptide processing +
                                                                is-asterol regulatory element binding protein cleavage +
                                                                is-avacuolar protein processing +
                                                                is-aviral protein processing
                                                                is-azymogen activation [GO:0031638] (101 genes, 133 annotations)
                                                                        is-aactivation of cysteine-type endopeptidase activity +
                                                                        is-aplasminogen activation +
                                                                        is-atrypsinogen activation
                                                                        is-azymogen activation in other organism +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein maturation
                                                is-aprotein processing
                                                        is-aactivation of plasma proteins involved in acute inflammatory response +
                                                        is-aCAAX-box protein processing
                                                        is-adibasic protein processing +
                                                        is-amitochondrial protein processing +
                                                        negatively-regulatesnegative regulation of protein processing +
                                                        is-aNotch receptor processing, ligand-independent
                                                        is-apeptide bond cleavage involved in epidermal growth factor receptor ligand maturation
                                                        is-apeptide hormone processing +
                                                        positively-regulatespositive regulation of protein processing +
                                                        is-aprotein autoprocessing
                                                        is-aprotein initiator methionine removal involved in protein maturation
                                                        is-aprotein processing in phagocytic vesicle
                                                        is-aprotein splicing +
                                                        regulatesregulation of protein processing +
                                                        is-asignal peptide processing +
                                                        is-asterol regulatory element binding protein cleavage +
                                                        is-avacuolar protein processing +
                                                        is-aviral protein processing
                                                        is-azymogen activation [GO:0031638] (101 genes, 133 annotations)
                                                                is-aactivation of cysteine-type endopeptidase activity +
                                                                is-aplasminogen activation +
                                                                is-atrypsinogen activation
                                                                is-azymogen activation in other organism +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory