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Gene Ontology Browser
Term Detail
GO term:blood coagulation
Synonym: blood clotting
GO id:GO:0007596
Definition:The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of body fluid levels
                                        is-ahemostasis
                                                is-ablood coagulation [GO:0007596] (165 genes, 257 annotations)
                                                        part-ofblood coagulation, fibrin clot formation +
                                                        negatively-regulatesnegative regulation of blood coagulation +
                                                        part-ofplatelet activation +
                                                        positively-regulatespositive regulation of blood coagulation +
                                                        regulatesregulation of blood coagulation +
                                                        part-ofthrombocyte activation
                                                is-ahemolymph coagulation
                                                negatively-regulatesnegative regulation of hemostasis +
                                                positively-regulatespositive regulation of hemostasis +
                                                regulatesregulation of hemostasis +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-acoagulation
                                        is-ablood coagulation [GO:0007596] (165 genes, 257 annotations)
                                                part-ofblood coagulation, fibrin clot formation +
                                                negatively-regulatesnegative regulation of blood coagulation +
                                                part-ofplatelet activation +
                                                positively-regulatespositive regulation of blood coagulation +
                                                regulatesregulation of blood coagulation +
                                                part-ofthrombocyte activation
                                        is-ahemolymph coagulation
                                        negatively-regulatesnegative regulation of coagulation +
                                        positively-regulatespositive regulation of coagulation +
                                        regulatesregulation of coagulation +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-aregulation of body fluid levels
                                        is-ahemostasis
                                                is-ablood coagulation [GO:0007596] (165 genes, 257 annotations)
                                                        part-ofblood coagulation, fibrin clot formation +
                                                        negatively-regulatesnegative regulation of blood coagulation +
                                                        part-ofplatelet activation +
                                                        positively-regulatespositive regulation of blood coagulation +
                                                        regulatesregulation of blood coagulation +
                                                        part-ofthrombocyte activation
                                                is-ahemolymph coagulation
                                                negatively-regulatesnegative regulation of hemostasis +
                                                positively-regulatespositive regulation of hemostasis +
                                                regulatesregulation of hemostasis +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-aresponse to wounding
                                        is-awound healing
                                                part-ofangiogenesis involved in wound healing +
                                                part-ofblood coagulation [GO:0007596] (165 genes, 257 annotations)
                                                        part-ofblood coagulation, fibrin clot formation +
                                                        negatively-regulatesnegative regulation of blood coagulation +
                                                        part-ofplatelet activation +
                                                        positively-regulatespositive regulation of blood coagulation +
                                                        regulatesregulation of blood coagulation +
                                                        part-ofthrombocyte activation
                                                part-ofcallus formation
                                                part-ofepiboly involved in wound healing +
                                                part-ofepithelium regeneration +
                                                part-ofhemolymph coagulation
                                                negatively-regulatesnegative regulation of wound healing +
                                                part-ofplasma membrane repair
                                                part-ofpositive regulation of epithelial cell proliferation involved in wound healing
                                                positively-regulatespositive regulation of wound healing +
                                                regulatesregulation of wound healing +
                                                part-ofscab formation
                                                part-oftissue regeneration +
                                                is-awound healing involved in inflammatory response +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-acoagulation
                                        is-ablood coagulation [GO:0007596] (165 genes, 257 annotations)
                                                part-ofblood coagulation, fibrin clot formation +
                                                negatively-regulatesnegative regulation of blood coagulation +
                                                part-ofplatelet activation +
                                                positively-regulatespositive regulation of blood coagulation +
                                                regulatesregulation of blood coagulation +
                                                part-ofthrombocyte activation
                                        is-ahemolymph coagulation
                                        negatively-regulatesnegative regulation of coagulation +
                                        positively-regulatespositive regulation of coagulation +
                                        regulatesregulation of coagulation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-aregulation of body fluid levels
                                        is-ahemostasis
                                                is-ablood coagulation [GO:0007596] (165 genes, 257 annotations)
                                                        part-ofblood coagulation, fibrin clot formation +
                                                        negatively-regulatesnegative regulation of blood coagulation +
                                                        part-ofplatelet activation +
                                                        positively-regulatespositive regulation of blood coagulation +
                                                        regulatesregulation of blood coagulation +
                                                        part-ofthrombocyte activation
                                                is-ahemolymph coagulation
                                                negatively-regulatesnegative regulation of hemostasis +
                                                positively-regulatespositive regulation of hemostasis +
                                                regulatesregulation of hemostasis +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory