Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCR
  • Mouse genes Bcr
  • Rat genes Bcr
  • Zfish genes bcr,si:dkey-91m11.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Bcr	IPI	RGD:1316156	Rat	PMID:10403766|RGD:1600513
Molecular Function	GO:0005096	GTPase activator activity	BCR	IDA		Human	PMID:1903516
Molecular Function	GO:0005096	GTPase activator activity	BCR	IDA		Human	PMID:7479768
Molecular Function	GO:0005096	GTPase activator activity	Bcr	IDA		Mouse	PMID:17116687
Molecular Function	GO:0005096	GTPase activator activity	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:19703997
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	BCR	IMP		Human	PMID:23940119
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	BCR	IDA		Human	PMID:7479768
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P62993	Human	PMID:10887132
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P78352	Human	PMID:20962234
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P62993	Human	PMID:21706016
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:Q9H2K2	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:A2AM67	Human	PMID:25331951
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:Q6ZV89-1	Human	PMID:25331951
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:Q8JZW5	Human	PMID:25331951
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P62993	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P62993	Human	PMID:8112292
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P62993	Human	PMID:8955135
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P62993	Human	PMID:8995379
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P62993	Human	PMID:9174058
Molecular Function	GO:0005515	protein binding	BCR	IPI	UniProtKB:P62993	Human	PMID:9178913
Molecular Function	GO:0005515	protein binding	Bcr	IPI	UniProtKB:Q8JZW5	Mouse	MGI:MGI:5608604|PMID:25331951
Molecular Function	GO:0005515	protein binding	Bcr	IPI	PR:Q640L3	Mouse	PMID:17000758
Molecular Function	GO:0005515	protein binding	Bcr	IPI	UniProtKB:P31016	Rat	PMID:20962234|RGD:13702252
Cellular Component	GO:0005737	cytoplasm	Bcr	IDA		Rat	PMID:10403766|RGD:1600513
Cellular Component	GO:0005829	cytosol	Bcr	IDA		Mouse	PMID:17116687
Cellular Component	GO:0070062	extracellular exosome	BCR	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Bcr	IMP		Mouse	PMID:20962234
Cellular Component	GO:0098978	glutamatergic synapse	Bcr	IDA		Mouse	PMID:20962234
Cellular Component	GO:0098978	glutamatergic synapse	Bcr	IDA		Rat	PMID:20962234|RGD:13702252
Cellular Component	GO:0016020	membrane	BCR	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	Bcr	IDA		Mouse	PMID:17116687
Cellular Component	GO:0014069	postsynaptic density	Bcr	IDA		Mouse	MGI:MGI:5608604|PMID:25331951
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Bcr	IDA		Rat	PMID:20962234|RGD:13702252
Cellular Component	GO:0032991	protein-containing complex	BCR	IDA		Human	PMID:23382219
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Bcr	IMP		Mouse	PMID:20962234
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Bcr	IDA		Mouse	PMID:20962234
Biological Process	GO:0030036	actin cytoskeleton organization	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:17116687
Biological Process	GO:0090630	activation of GTPase activity	BCR	IMP		Human	PMID:23940119
Biological Process	GO:0090630	activation of GTPase activity	BCR	IDA		Human	PMID:7479768
Biological Process	GO:0007420	brain development	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:11684658
Biological Process	GO:0016477	cell migration	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:17116687
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:7889565
Biological Process	GO:0060216	definitive hemopoiesis	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:7889565
Biological Process	GO:0051649	establishment of localization in cell	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:17116687
Biological Process	GO:0048041	focal adhesion assembly	BCR	IMP		Human	PMID:23940119
Biological Process	GO:0048872	homeostasis of number of cells	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:7889565
Biological Process	GO:0042472	inner ear morphogenesis	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:11921339
Biological Process	GO:0065002	intracellular protein transmembrane transport	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:7889565
Biological Process	GO:0030216	keratinocyte differentiation	BCR	IMP		Human	PMID:23940119
Biological Process	GO:1905517	macrophage migration	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:17116687
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Bcr	IDA		Mouse	PMID:20962234
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Bcr	IMP		Mouse	PMID:20962234
Biological Process	GO:0060313	negative regulation of blood vessel remodeling	Bcr	IMP		Mouse	MGI:MGI:5475443|PMID:23152932
Biological Process	GO:0002692	negative regulation of cellular extravasation	Bcr	IMP		Mouse	MGI:MGI:5475443|PMID:23152932
Biological Process	GO:0050728	negative regulation of inflammatory response	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:19703997
Biological Process	GO:1905522	negative regulation of macrophage migration	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:17116687
Biological Process	GO:0043314	negative regulation of neutrophil degranulation	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:19703997
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:7889565
Biological Process	GO:0060268	negative regulation of respiratory burst	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:7889565
Biological Process	GO:0050885	neuromuscular process controlling balance	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:11921339
Biological Process	GO:0043312	neutrophil degranulation	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:19703997
Biological Process	GO:0006909	phagocytosis	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:17116687
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Bcr	IDA		Rat	PMID:11560856|RGD:1600511
Biological Process	GO:0050766	positive regulation of phagocytosis	Bcr	IGI	MGI:MGI:107771	Mouse	PMID:17116687
Biological Process	GO:0046777	protein autophosphorylation	Bcr	IDA		Rat	PMID:11560856|RGD:1600511
Biological Process	GO:0051726	regulation of cell cycle	Bcr	IDA		Mouse	PMID:11809706
Biological Process	GO:0051171	regulation of nitrogen compound metabolic process	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:7889565
Biological Process	GO:0035023	regulation of Rho protein signal transduction	BCR	IMP		Human	PMID:23940119
Biological Process	GO:0043114	regulation of vascular permeability	Bcr	IMP		Mouse	MGI:MGI:5475443|PMID:23152932
Biological Process	GO:0003014	renal system process	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:7889565
Biological Process	GO:0032496	response to lipopolysaccharide	Bcr	IMP	MGI:MGI:2154396	Mouse	PMID:19703997
Biological Process	GO:0007264	small GTPase mediated signal transduction	BCR	IMP		Human	PMID:23940119

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern