| GO term: | guanyl-nucleotide exchange factor activity |
| Synonym: | GDP-dissociation stimulator activity |
| Synonym: | GDS |
| Synonym: | GEF |
| Synonym: | GNRP |
| Synonym: | guanyl-nucleotide release factor activity |
| Synonym: | guanyl-nucleotide releasing factor |
| GO id: | GO:0005085 |
| Definition: | Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionenzyme regulator activitynucleoside-triphosphatase regulator activityGTPase regulator activityGTPase activator activity +GTPase inhibitor activityguanyl-nucleotide exchange factor activity [GO:0005085] (167 genes, 297 annotations)ARF guanyl-nucleotide exchange factor activitycyclic nucleotide-dependent guanyl-nucleotide exchange factor activityRas guanyl-nucleotide exchange factor activity +Sar guanyl-nucleotide exchange factor activitysmall GTPase regulator activity +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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